A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Dennis, S.
	Articles by Papkoff, J.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Dennis, S.
	Articles by Papkoff, J.


Social Bookmarking

	What's this?

Aberle, H., Bauer, A., Stappert, J., Kispert, A. and Kemler, R (1997). -catenin is a target for the ubiquitin-proteasome pathway. EMBO J 16, 3797-3804.[Medline]

Bhanot, P., Brink, M., Harryman-Samos, C., Hsieh, J.-C., Wang, Y., Macke, J. P., Andrew, d., Nathans, J. and Nusse, R (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230.[Medline]

Bienz, M (1998). TCF: transcriptional activator or repressor?. Curr. Opin. Cell Biol 10, 366-372.[Medline]

Bradley, R. S., Cowin, P. and Brown, A. M. C (1993). Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. J. Cell Biol 123, 1857-1865.[Abstract/Free Full Text]

Cadigan, K. M. and Nusse, R (1997). Wnt signaling: a common theme in animal development. Genes & Develop 11, 3286-3305.[Free Full Text]

Clevers, H. and Van De Wetering, M (1997). TCF/LEF factors earn their wings. Trends Genet 13, 485-489.[Medline]

Cox, R. T. and Peifer, M (1998). Wingless signaling: The inconvenient complexities of life. Curr. Biol 8, 140-.

Finch, P. W., He, X., Kelley, M. J., Uren, A., Schaudies, R. P., Popescu, N. C., Rudikoff, S., Aaronson, S. A., Varmus, H. A. and Rubin, J. S (1997). Purification and molecular cloning of a secreted, frizzled-related antagonist of Wnt action. Proc. Nat. Acad. Sci. USA 94, 6770-6775.[Abstract/Free Full Text]

Hinck, L., Nelson, W. J. and Papkoff, J (1994). Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing-catenin binding to the cell adhesion protein cadherin. J. Cell Biol 124, 729-741.[Abstract/Free Full Text]

Hoang, B., Moos, M., Jr., Vukicevic, S. and Luyten, F. P (1996). Primary structure and tissue distribution of FRZB, a novel protein related to Drosphila frizzled, suggest a role in skeletal morphogenesis. J. Biol. Chem 271, 26131-26137.[Abstract/Free Full Text]

Hoang, B. H., Thomas, J. T., Abdul-Karim, F. W., Correia, K. M., Conlon, R. A., Luyten, F. P. and Ballock, R. T (1998). Expression pattern of two frizzled -related genes, Frzb-1 and Sfrp-1 , During mouse embryogenesis suggests a role for modulating action of Wnt family members. Dev. Dynam 212, 364-372.[Medline]

Klingensmith, J. and Nusse, R (1994). Signaling by wingless in Drosophila. Dev. Biol 166, 396-414.[Medline]

Leyns, L., Bouwmeester, T., Kim, S.-H., Piccolo, S. and De Robertis, E. M (1997). Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann Organizer. Cell 88, 747-756.[Medline]

Lin, K., Wang, S., Julius, M. A., Kitajewski, J., Moos, M., Jr. and Luyten, F. P (1997). The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling. Proc. Nat. Acad. Sci. USA 94, 11196-11200.[Abstract/Free Full Text]

Mayr, T., U., D., Kuhl, M., Drexler, H. C. A., Lottspeich, F., Deutzmann, R., Wedlich, D. and Risau, W (1997). Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mech. Dev 63, 109-125.[Medline]

McMahon, A. P. and Moon, R. T (1989). Ectopic expression of the proto-oncogenein Xenopus embryos leads to duplication of the embryonic axis. Cell 58, 1075-1084.[Medline]

Melkonyan, H. S., Chang, W. C., Shapiro, J. P., Mahedevappa, M., Fitzpatrick, P. A., Kiefer, M. C., Tomei, L. D. and Urmansky, S. R (1997). SARPs: A family of secreted apoptosis-related proteins. Proc. Nat. Acad. Sci. USA 94, 13636-13641.[Abstract/Free Full Text]

Miller, J. R. and Moon, R. T (1996). Signal transduction through-catenin and specification of cell fate during embryogenesis. Genes Dev 10, 2527-2539.[Free Full Text]

Moon, R. T., Brown, J. D., Yang-Snyder, J. A. and Miller, J. R (1997). Structurally related receptors and antagonists compete for secreted Wnt ligands. Cell 88, 725-728.[Medline]

Nusse, R. and Varmus, H. E (1992). Wnt genes. Cell 69, 1073-1087.[Medline]

Nusse, R (1997). A versatile transcriptional effector of wingless signaling. Cell 89, 321-323.[Medline]

Olson, D. J., Christian, J. L. and Moon, R. T (1991). Effect of Wnt-1 and related proteins on gap junctional communication in Xenopus embryos. Science 252, 1173-1176.[Free Full Text]

Orford, K., Crockett, C., Jensen, J. P., Weissman, A. M. and Byers, S. W (1997). Serine phosphorylation-regulated ubiquitination and degradation of-catenin. J. Biol. Chem 272, 24735-24738.[Abstract/Free Full Text]

Ozawa, M., Baribault, H. and Kemler, R (1989). The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J 8, 1711-1717.[Medline]

Papkoff, J., Brown, A. M. C. and Varmus, H. E (1987). The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway. Mol. Cell. Biol 7, 3978-3984.[Abstract/Free Full Text]

Papkoff, J (1989). Inducible overexpression and secretion of Int-1 protein. Mol. Cell. Biol 9, 3377-3384.[Abstract/Free Full Text]

Papkoff, J. and Schryver, B (1990). Secreted int-1 protein is associated with the cell surface. Mol. Cell. Biol 10, 2723-2730.[Abstract/Free Full Text]

Papkoff, J., Rubinfeld, B., Schryver, B. and Polakis, P (1996). Wnt-1regulates free pools of catenins and stabilizes APC-catenin complexes. Mol. Cell Biol 16, 2128-2134.[Abstract]

Papkoff, J (1997). Regulation of complexed and free catenin pools by distinct mechanisms: Differential effects of Wnt-1 and v-Src. J. Biol. Chem 272, 4536-4543.[Abstract/Free Full Text]

Papkoff, J. and Aikawa, M (1998). Wnt-1 and HGF regulate GSK3activity and -catenin signaling in mammary epithelial cells. Biochem. Biophys. Res. Commun 247, 851-858.[Medline]

Peifer, M., McCrea, P. D., Green, K. J., Wieschaus, E. and Gumbiner, B. M (1992). The vertebrate adhesive junction proteins-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties. J. Cell Biol 118, 681-691.[Abstract/Free Full Text]

Perrimon, N (1996). Serpentine proteins slither into the Wingless and Hedgehog fields. Cell 86, 513-516.[Medline]

Phillips, R. G. and Whittle, J. R. S (1993). Wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development 118, 427-438.[Abstract]

Polakis, P (1997). The adenomatous polyposis coli (APC) tumor suppressor. Biochim. Biophys. Acta 1332, 127-.

Rattner, A., Hsieh, J.-C., Smallwood, P. M., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. and Nathans, J (1997). A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc. Nat. Acad. Sci. USA 94, 2859-2863.[Abstract/Free Full Text]

Shimizu, H., Julius, M. A., Giarre, M., Zheng, Z., Brown, A. M. and Kitajewski, J (1997). Transformation by Wnt family proteins correlates with regulation of beta-catenin. Cell Growth Differ 8, 1349-1358.[Abstract]

Siegfried, E. and Perrimon, N (1994). Drosphila wingless: A paradigm for the function and mechanism of Wnt signaling. BioEssays 16, 395-404.[Medline]

Skaer, H. and Martinez Arias, A (1992). The wingless product is required for cell proliferation in the Malphigian tubule anlage of Drosophila melanogaster. Development 116, 745-754.[Abstract]

Smolich, B. D., McMahon, J. A., McMahon, A. P. and Papkoff, J (1993). Wnt family proteins are secreted and associated with the cell surface. Mol. Biol. Cell 4, 1267-1275.[Abstract]

Takeichi, M (1991). Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.[Abstract/Free Full Text]

Wang, S., Krinks, M., Lin, K., Luyten, F. P. and Moos, M. Jr (1997). Frzb, a secreted protein expressed in the Spemann Organizer, binds and inhibits Wnt-8. Cell 88, 757-766.[Medline]

Wang, S., Krinks, M. and Moos, M. Jr (1997). Frzb-1, an antagonist of Wnt-1 and Wnt-8, does not block signaling by Wnts-3A,-5A, or-11. Biochem. Biophys. Res. Commun 236, 502-504.[Medline]

Willert, K. and Nusse, R (1998). -catenin: a key mediator of Wnt signaling. Curr. Opin. Gen. Dev 8, 95-102.[Medline]

Wong, G. T., Gavin, B. J. and McMahon, A. P (1994). Differential transformation of mammary epithelial cells by Wnt genes. Mol. Cell. Biol 14, 6278-6286.[Abstract/Free Full Text]

Xu, W., D'Amore, P. A. and Sokol, S. Y (1998). Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist. Development 125, 4767-4776.[Abstract]

Zorn, A. M (1997). Cell-cell signalling: Frog frizbees. Curr. Biol 7, 501-.

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

S. Saini, J. Liu, S. Yamamura, S. Majid, K. Kawakami, H. Hirata, and R. Dahiya
Functional Significance of Secreted Frizzled-Related Protein 1 in Metastatic Renal Cell Carcinomas
Cancer Res., September 1, 2009; 69(17): 6815 - 6822.
[Abstract] [Full Text] [PDF]

D. Romaker, M. Puetz, S. Teschner, J. Donauer, M. Geyer, P. Gerke, B. Rumberger, B. Dworniczak, P. Pennekamp, B. Buchholz, et al.
Increased Expression of Secreted Frizzled-Related Protein 4 in Polycystic Kidneys
J. Am. Soc. Nephrol., January 1, 2009; 20(1): 48 - 56.
[Abstract] [Full Text] [PDF]

P. Bovolenta, P. Esteve, J. M. Ruiz, E. Cisneros, and J. Lopez-Rios
Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease
J. Cell Sci., March 15, 2008; 121(6): 737 - 746.
[Abstract] [Full Text] [PDF]

P. Dufourcq, L. Leroux, J. Ezan, B. Descamps, J.-M. D. Lamaziere, P. Costet, C. Basoni, C. Moreau, U. Deutsch, T. Couffinhal, et al.
Regulation of Endothelial Cell Cytoskeletal Reorganization by a Secreted Frizzled-Related Protein-1 and Frizzled 4- and Frizzled 7-Dependent Pathway: Role in Neovessel Formation
Am. J. Pathol., January 1, 2008; 172(1): 37 - 49.
[Abstract] [Full Text] [PDF]

M. Kobune, H. Chiba, J. Kato, K. Kato, K. Nakamura, Y. Kawano, K. Takada, R. Takimoto, T. Takayama, H. Hamada, et al.
Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism
Mol. Cancer Ther., June 1, 2007; 6(6): 1774 - 1784.
[Abstract] [Full Text] [PDF]

G. Peng and M. Westerfield
Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists
Development, August 15, 2006; 133(16): 3191 - 3200.
[Abstract] [Full Text] [PDF]

C. Lamy, U. Rothbacher, D. Caillol, and P. Lemaire
Ci-FoxA-a is the earliest zygotic determinant of the ascidian anterior ectoderm and directly activates Ci-sFRP1/5
Development, August 1, 2006; 133(15): 2835 - 2844.
[Abstract] [Full Text] [PDF]

T. Pukrop, F. Klemm, Th. Hagemann, D. Gradl, M. Schulz, S. Siemes, L. Trumper, and C. Binder
Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines
PNAS, April 4, 2006; 103(14): 5454 - 5459.
[Abstract] [Full Text] [PDF]

W. Satoh, T. Gotoh, Y. Tsunematsu, S. Aizawa, and A. Shimono
Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis
Development, March 15, 2006; 133(6): 989 - 999.
[Abstract] [Full Text] [PDF]

M. S. Joesting, S. Perrin, B. Elenbaas, S. E. Fawell, J. S. Rubin, O. E. Franco, S. W. Hayward, G. R. Cunha, and P. C. Marker
Identification of SFRP1 as a Candidate Mediator of Stromal-to-Epithelial Signaling in Prostate Cancer
Cancer Res., November 15, 2005; 65(22): 10423 - 10430.
[Abstract] [Full Text] [PDF]

L. Barandon, P. Dufourcq, P. Costet, C. Moreau, C. Allieres, D. Daret, P. D. Santos, J.-M. D. Lamaziere, T. Couffinhal, and C. Duplaa
Involvement of FrzA/sFRP-1 and the Wnt/Frizzled Pathway in Ischemic Preconditioning
Circ. Res., June 24, 2005; 96(12): 1299 - 1306.
[Abstract] [Full Text] [PDF]

J. Ezan, L. Leroux, L. Barandon, P. Dufourcq, B. Jaspard, C. Moreau, C. Allieres, D. Daret, T. Couffinhal, and C. Duplaa
FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo
Cardiovasc Res, September 1, 2004; 63(4): 731 - 738.
[Abstract] [Full Text] [PDF]

P. Dufourcq, T. Couffinhal, J. Ezan, L. Barandon, C. Moreau, D. Daret, and C. Duplaa
FrzA, a Secreted Frizzled Related Protein, Induced Angiogenic Response
Circulation, December 10, 2002; 106(24): 3097 - 3103.
[Abstract] [Full Text] [PDF]

J.-i. Hanai, J. Gloy, S. A. Karumanchi, S. Kale, J. Tang, G. Hu, B. Chan, R. Ramchandran, V. Jha, V. P. Sukhatme, et al.
Endostatin is a potential inhibitor of Wnt signaling
J. Cell Biol., August 5, 2002; 158(3): 529 - 539.
[Abstract] [Full Text] [PDF]

V. A. Schneider and M. Mercola
Wnt antagonism initiates cardiogenesis in Xenopus laevis
Genes & Dev., February 1, 2001; 15(3): 304 - 315.
[Abstract] [Full Text]

P. Polakis
Wnt signaling and cancer
Genes & Dev., August 1, 2000; 14(15): 1837 - 1851.
[Full Text]

A. S. Kim, S. A. Anderson, J. L. R. Rubenstein, D. H. Lowenstein, and S. J. Pleasure
Pax-6 Regulates Expression of SFRP-2 and Wnt-7b in the Developing CNS
J. Neurosci., March 1, 2001; 21(5): RC132 - RC132.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Dennis, S.

Articles by Papkoff, J.

Search for Related Content

PubMed

PubMed Citation

Articles by Dennis, S.

Articles by Papkoff, J.

Social Bookmarking

What's this?

				D. Romaker, M. Puetz, S. Teschner, J. Donauer, M. Geyer, P. Gerke, B. Rumberger, B. Dworniczak, P. Pennekamp, B. Buchholz, et al. Increased Expression of Secreted Frizzled-Related Protein 4 in Polycystic Kidneys J. Am. Soc. Nephrol., January 1, 2009; 20(1): 48 - 56. [Abstract] [Full Text] [PDF]

				P. Bovolenta, P. Esteve, J. M. Ruiz, E. Cisneros, and J. Lopez-Rios Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease J. Cell Sci., March 15, 2008; 121(6): 737 - 746. [Abstract] [Full Text] [PDF]

				P. Dufourcq, L. Leroux, J. Ezan, B. Descamps, J.-M. D. Lamaziere, P. Costet, C. Basoni, C. Moreau, U. Deutsch, T. Couffinhal, et al. Regulation of Endothelial Cell Cytoskeletal Reorganization by a Secreted Frizzled-Related Protein-1 and Frizzled 4- and Frizzled 7-Dependent Pathway: Role in Neovessel Formation Am. J. Pathol., January 1, 2008; 172(1): 37 - 49. [Abstract] [Full Text] [PDF]

				M. Kobune, H. Chiba, J. Kato, K. Kato, K. Nakamura, Y. Kawano, K. Takada, R. Takimoto, T. Takayama, H. Hamada, et al. Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism Mol. Cancer Ther., June 1, 2007; 6(6): 1774 - 1784. [Abstract] [Full Text] [PDF]

				G. Peng and M. Westerfield Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists Development, August 15, 2006; 133(16): 3191 - 3200. [Abstract] [Full Text] [PDF]

				C. Lamy, U. Rothbacher, D. Caillol, and P. Lemaire Ci-FoxA-a is the earliest zygotic determinant of the ascidian anterior ectoderm and directly activates Ci-sFRP1/5 Development, August 1, 2006; 133(15): 2835 - 2844. [Abstract] [Full Text] [PDF]

				T. Pukrop, F. Klemm, Th. Hagemann, D. Gradl, M. Schulz, S. Siemes, L. Trumper, and C. Binder Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines PNAS, April 4, 2006; 103(14): 5454 - 5459. [Abstract] [Full Text] [PDF]

				W. Satoh, T. Gotoh, Y. Tsunematsu, S. Aizawa, and A. Shimono Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis Development, March 15, 2006; 133(6): 989 - 999. [Abstract] [Full Text] [PDF]

				M. S. Joesting, S. Perrin, B. Elenbaas, S. E. Fawell, J. S. Rubin, O. E. Franco, S. W. Hayward, G. R. Cunha, and P. C. Marker Identification of SFRP1 as a Candidate Mediator of Stromal-to-Epithelial Signaling in Prostate Cancer Cancer Res., November 15, 2005; 65(22): 10423 - 10430. [Abstract] [Full Text] [PDF]

				L. Barandon, P. Dufourcq, P. Costet, C. Moreau, C. Allieres, D. Daret, P. D. Santos, J.-M. D. Lamaziere, T. Couffinhal, and C. Duplaa Involvement of FrzA/sFRP-1 and the Wnt/Frizzled Pathway in Ischemic Preconditioning Circ. Res., June 24, 2005; 96(12): 1299 - 1306. [Abstract] [Full Text] [PDF]

				J. Ezan, L. Leroux, L. Barandon, P. Dufourcq, B. Jaspard, C. Moreau, C. Allieres, D. Daret, T. Couffinhal, and C. Duplaa FrzA/sFRP-1, a secreted antagonist of the Wnt-Frizzled pathway, controls vascular cell proliferation in vitro and in vivo Cardiovasc Res, September 1, 2004; 63(4): 731 - 738. [Abstract] [Full Text] [PDF]

				P. Dufourcq, T. Couffinhal, J. Ezan, L. Barandon, C. Moreau, D. Daret, and C. Duplaa FrzA, a Secreted Frizzled Related Protein, Induced Angiogenic Response Circulation, December 10, 2002; 106(24): 3097 - 3103. [Abstract] [Full Text] [PDF]

				J.-i. Hanai, J. Gloy, S. A. Karumanchi, S. Kale, J. Tang, G. Hu, B. Chan, R. Ramchandran, V. Jha, V. P. Sukhatme, et al. Endostatin is a potential inhibitor of Wnt signaling J. Cell Biol., August 5, 2002; 158(3): 529 - 539. [Abstract] [Full Text] [PDF]

				V. A. Schneider and M. Mercola Wnt antagonism initiates cardiogenesis in Xenopus laevis Genes & Dev., February 1, 2001; 15(3): 304 - 315. [Abstract] [Full Text]

				P. Polakis Wnt signaling and cancer Genes & Dev., August 1, 2000; 14(15): 1837 - 1851. [Full Text]

				A. S. Kim, S. A. Anderson, J. L. R. Rubenstein, D. H. Lowenstein, and S. J. Pleasure Pax-6 Regulates Expression of SFRP-2 and Wnt-7b in the Developing CNS J. Neurosci., March 1, 2001; 21(5): RC132 - RC132. [Abstract] [Full Text] [PDF]