Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages

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Articles by Suen, P. W.

Articles by Lowell, C. A.

				D. Okutani, M. Lodyga, B. Han, and M. Liu Src protein tyrosine kinase family and acute inflammatory responses Am J Physiol Lung Cell Mol Physiol, August 1, 2006; 291(2): L129 - L141. [Abstract] [Full Text] [PDF]

				C. Giagulli, L. Ottoboni, E. Caveggion, B. Rossi, C. Lowell, G. Constantin, C. Laudanna, and G. Berton The Src Family Kinases Hck and Fgr Are Dispensable for Inside-Out, Chemoattractant-Induced Signaling Regulating beta2 Integrin Affinity and Valency in Neutrophils, but Are Required for beta2 Integrin-Mediated Outside-In Signaling Involved in Sustained Adhesion J. Immunol., July 1, 2006; 177(1): 604 - 611. [Abstract] [Full Text] [PDF]

				M. A. Sanjuan, N. Rao, K.-T. A. Lai, Y. Gu, S. Sun, A. Fuchs, W.-P. Fung-Leung, M. Colonna, and L. Karlsson CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion. J. Cell Biol., March 27, 2006; 172(7): 1057 - 1068. [Abstract] [Full Text] [PDF]

				E. G. Arias-Salgado, F. Haj, C. Dubois, B. Moran, A. Kasirer-Friede, B. C. Furie, B. Furie, B. G. Neel, and S. J. Shattil PTP-1B is an essential positive regulator of platelet integrin signaling J. Cell Biol., August 29, 2005; 170(5): 837 - 845. [Abstract] [Full Text] [PDF]

				V. Munugalavadla, J. Borneo, D. A. Ingram, and R. Kapur p85{alpha} subunit of class IA PI-3 kinase is crucial for macrophage growth and migration Blood, July 1, 2005; 106(1): 103 - 109. [Abstract] [Full Text] [PDF]

				F. J. Pixley, Y. Xiong, R. Y.-L. Yu, E. A. Sahai, E. R. Stanley, and B. H. Ye BCL6 suppresses RhoA activity to alter macrophage morphology and motility J. Cell Sci., May 1, 2005; 118(9): 1873 - 1883. [Abstract] [Full Text] [PDF]

				R. A. Clemens, S. A. Newbrough, E. Y. Chung, S. Gheith, A. L. Singer, G. A. Koretzky, and E. J. Peterson PRAM-1 Is Required for Optimal Integrin-Dependent Neutrophil Function Mol. Cell. Biol., December 15, 2004; 24(24): 10923 - 10932. [Abstract] [Full Text] [PDF]

				W. S. Choi, T. Hiragun, J. H. Lee, Y. M. Kim, H.-P. Kim, A. Chahdi, E. Her, J. W. Han, and M. A. Beaven Activation of RBL-2H3 Mast Cells Is Dependent on Tyrosine Phosphorylation of Phospholipase D2 by Fyn and Fgr Mol. Cell. Biol., August 15, 2004; 24(16): 6980 - 6992. [Abstract] [Full Text] [PDF]

				P. Scapini, M. Morini, C. Tecchio, S. Minghelli, E. Di Carlo, E. Tanghetti, A. Albini, C. Lowell, G. Berton, D. M. Noonan, et al. CXCL1/Macrophage Inflammatory Protein-2-Induced Angiogenesis In Vivo Is Mediated by Neutrophil-Derived Vascular Endothelial Growth Factor-A J. Immunol., April 15, 2004; 172(8): 5034 - 5040. [Abstract] [Full Text] [PDF]

				N. Yokoyama and W. T. Miller Biochemical Properties of the Cdc42-associated Tyrosine Kinase ACK1: SUBSTRATE SPECIFICITY, AUTOPHOSPHORYLATION, AND INTERACTION WITH Hck J. Biol. Chem., November 28, 2003; 278(48): 47713 - 47723. [Abstract] [Full Text] [PDF]

				D. Pradip, X. Peng, and D. L. Durden Rac2 Specificity in Macrophage Integrin Signaling: POTENTIAL ROLE FOR Syk KINASE J. Biol. Chem., October 24, 2003; 278(43): 41661 - 41669. [Abstract] [Full Text] [PDF]

				S. Pereira and C. Lowell The Lyn Tyrosine Kinase Negatively Regulates Neutrophil Integrin Signaling J. Immunol., August 1, 2003; 171(3): 1319 - 1327. [Abstract] [Full Text] [PDF]

				G. O. C. Cory, R. Garg, R. Cramer, and A. J. Ridley Phosphorylation of Tyrosine 291 Enhances the Ability of WASp to Stimulate Actin Polymerization and Filopodium Formation J. Biol. Chem., November 15, 2002; 277(47): 45115 - 45121. [Abstract] [Full Text] [PDF]

				M. Ernst, M. Inglese, G. M. Scholz, K. W. Harder, F. J. Clay, S. Bozinovski, P. Waring, R. Darwiche, T. Kay, P. Sly, et al. Constitutive Activation of the Src Family Kinase Hck Results in Spontaneous Pulmonary Inflammation and an Enhanced Innate Immune Response J. Exp. Med., September 2, 2002; 196(5): 589 - 604. [Abstract] [Full Text] [PDF]

				M. M. Monick, L. Powers, N. Butler, T. Yarovinsky, and G. W. Hunninghake Interaction of matrix with integrin receptors is required for optimal LPS-induced MAP kinase activation Am J Physiol Lung Cell Mol Physiol, August 1, 2002; 283(2): L390 - L402. [Abstract] [Full Text] [PDF]

				M. P. Scott, F. Zappacosta, E. Y. Kim, R. S. Annan, and W. T. Miller Identification of Novel SH3 Domain Ligands for the Src Family Kinase Hck. WISKOTT-ALDRICH SYNDROME PROTEIN (WASP), WASP-INTERACTING PROTEIN (WIP), AND ELMO1 J. Biol. Chem., July 26, 2002; 277(31): 28238 - 28246. [Abstract] [Full Text] [PDF]

				L. Vicentini, P. Mazzi, E. Caveggion, S. Continolo, L. Fumagalli, J. A. Lapinet-Vera, C. A. Lowell, and G. Berton Fgr Deficiency Results in Defective Eosinophil Recruitment to the Lung During Allergic Airway Inflammation J. Immunol., June 15, 2002; 168(12): 6446 - 6454. [Abstract] [Full Text] [PDF]

				S. Carreno, E. Caron, C. Cougoule, L. J. Emorine, and I. Maridonneau-Parini p59Hck Isoform Induces F-actin Reorganization to Form Protrusions of the Plasma Membrane in a Cdc42- and Rac-dependent Manner J. Biol. Chem., May 31, 2002; 277(23): 21007 - 21016. [Abstract] [Full Text] [PDF]

				A. Obergfell, K. Eto, A. Mocsai, C. Buensuceso, S. L. Moores, J. S. Brugge, C. A. Lowell, and S. J. Shattil Coordinate interactions of Csk, Src, and Syk kinases with {alpha}IIb{beta}3 initiate integrin signaling to the cytoskeleton J. Cell Biol., April 15, 2002; 157(2): 265 - 275. [Abstract] [Full Text] [PDF]

				J. H. Lee, N. Kaminski, G. Dolganov, G. Grunig, L. Koth, C. Solomon, D. J. Erle, and D. Sheppard Interleukin-13 Induces Dramatically Different Transcriptional Programs in Three Human Airway Cell Types Am. J. Respir. Cell Mol. Biol., October 1, 2001; 25(4): 474 - 485. [Abstract] [Full Text] [PDF]

				P. Piccardoni, R. Sideri, S. Manarini, A. Piccoli, N. Martelli, G. de Gaetano, C. Cerletti, and V. Evangelista Platelet/polymorphonuclear leukocyte adhesion: a new role for SRC kinases in Mac-1 adhesive function triggered by P-selectin Blood, July 1, 2001; 98(1): 108 - 116. [Abstract] [Full Text] [PDF]

				S. Meconi, C. Capo, M. Remacle-Bonnet, G. Pommier, D. Raoult, and J.-L. Mege Activation of Protein Tyrosine Kinases by Coxiella burnetii: Role in Actin Cytoskeleton Reorganization and Bacterial Phagocytosis Infect. Immun., April 1, 2001; 69(4): 2520 - 2526. [Abstract] [Full Text] [PDF]

				S. Pereira, M. Zhou, A. Mocsai, and C. Lowell Resting Murine Neutrophils Express Functional {{alpha}}4 Integrins that Signal Through Src Family Kinases J. Immunol., March 15, 2001; 166(6): 4115 - 4123. [Abstract] [Full Text] [PDF]

				G. Scholz, S. D. Hartson, K. Cartledge, N. Hall, J. Shao, A. R. Dunn, and R. L. Matts p50Cdc37 Can Buffer the Temperature-Sensitive Properties of a Mutant of Hck Mol. Cell. Biol., September 15, 2000; 20(18): 6984 - 6995. [Abstract] [Full Text]

				S. Carreno, M.-E. Gouze, S. Schaak, L. J. Emorine, and I. Maridonneau-Parini Lack of Palmitoylation Redirects p59Hck from the Plasma Membrane to p61Hck-positive Lysosomes J. Biol. Chem., November 10, 2000; 275(46): 36223 - 36229. [Abstract] [Full Text] [PDF]

				J. M. Watson, T. W. Harding, V. Golubovskaya, J. S. Morris, D. Hunter, X. Li, J. S. Haskill, and H. S. Earp Inhibition of the Calcium-dependent Tyrosine Kinase (CADTK) Blocks Monocyte Spreading and Motility J. Biol. Chem., January 26, 2001; 276(5): 3536 - 3542. [Abstract] [Full Text] [PDF]