Induction of vascular smooth muscle cell tenascin-C gene expression by denatured type I collagen is dependent upon a beta3 integrin-mediated mitogen-activated protein kinase pathway and a 122-base pair promoter element

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Jones, P. L.
	Articles by Rabinovitch, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Jones, P. L.
	Articles by Rabinovitch, M.

Assoian, R. and Marcantonio, E (1996). The extracellular matrix as a cell cycle control element in atherschlerosis and restenosis. J. Clin. Invest 98, 2436-2439.[Medline]

Basbaum C. B. and Werb, Z (1996). Focalized proteolysis: spatial and temporal regulation of extracellular matrix degradation at the cell surface. Curr. Opin. Cell Biol 8, 731-738.

Bendeck, M., Zempo, N., Clowes, A., Galardy, R. and Reidy, M (1994). Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat. Circ. Res 75, 539-545.[Abstract/Free Full Text]

Brooks, P., Stromblad, S., Sanders, L., von Schalscha, T., Aimes, R., Stetler-Stevenson, W., Quigley, J. and Cheresh, D (1996). Localizationof matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with v3 integrin. Cell 85, 683-693.[Medline]

Chen, C. S., Mrksich, M., Huang, S., Whitesides, G. M. and Ingber, D. E (1997). Geometric control of cell life and death. Science 276, 1425-1428.[Abstract/Free Full Text]

Chen, Q., Kinsch, M. S., Lin, T. H., Burridge, K. and Juliano, R. L (1994). Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J. Biol. Chem 6, 26602-26605.

Chiquet-Ehrismann, R., Tannheimer, M., Koch, M., Brunner, A., Spring, J., Martin, D., Baumgartner, S. and Chiquet, M (1994). Tenascin-C expression by fibroblasts is elevated in stressed collagen gels. J. Cell Biol 127, 2093-2101.[Abstract/Free Full Text]

Chiquet-Ehrismann, R., Hagios, C. and Schenk, S (1995). The complexity of regulating tenascins. BioEssays 17, 873-878.[Medline]

Copertino, D. W., Jenkinson, S., Jones, F. S. and Edelman, G. M (1995). Structural and functional similarities between the promoters for mouse tenascin and chicken cytotactin. Proc. Natl. Acad. Sci. USA 92, 2131-2135.[Abstract/Free Full Text]

Copertino, D. W., Edelman, G. M. and Jones, F. S (1997). Multiple promoter elements differentially regulate the expression of the mouse tenascin gene. Proc. Natl. Acad. Sci. USA 94, 1846-1851.[Abstract/Free Full Text]

Davis, G. E (1992). Affinity of integrins for damaged extracellular matrix: Alpha v beta 3 binds to denatured collagen type I through RGD sites. Biochem. Biophys. Res. Commun 182, 1025-1031.[Medline]

Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J. and Saltiel, A. R (1995). A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92, 7686-7689.[Abstract/Free Full Text]

Eliceiri, B. P., Klemke, R., Stromblad, S. and Cheresh, D. A (1998). Integrinv 3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J. Cell Biol 140, 1255-1263.[Abstract/Free Full Text]

Folkman, J. and Moscona, A (1978). Role of cell shape in growth control. Nature 273, 345-349.[Medline]

Gherzi, R., Carnemolla, B., Siri, A., Ponassi, M., Balza, E. and Zardi, L (1995). Human tenascin gene. Structure of the 5-region, identification, and characterization of the transcription regulatory sequences. J. Biol. Chem 270, 3429-3434.[Abstract/Free Full Text]

Gherzi, R., Briata, P., Boncinelli, E., Ponassi, M., Querze, G., Viti F., Corte, G. and Zardi, L (1997). The human homeodomain protein OTX2 binds to the human tenascin-C promoter and trans-represses its activity in transfected cells. DNA Cell Biol 16, 559-567.[Medline]

Hedin, U., Bottger, B. A., Forsberg, E., Johansson, S. and Thyberg, J (1988). Diverse effects of fibronectin and laminin on phenotypic properties of cultured arterial smooth muscle cells. J. Cell Biol 107, 307-319.[Abstract/Free Full Text]

Hedin, U., Holm, J. and Hansson, G (1991). Induction of tenascin-C in rat arterial injury: relationship to altered smooth muscle cell phenotype. Am. J. Path 139, 649-656.[Abstract]

Hill, C. S. and Treisman, R (1995). Transcriptional Regulation by Extracellular signals; Mechanisms and Specificity. Cell 80, 199-211.[Medline]

Jones, F. S., Chalepakis, G., Gruss, P. and Edelman, G. M (1992). Activation of the cytotactin promoter by the homeobox-containing gene Evx-1. Proc. Natl. Acad. Sci. USA 89, 2091-2095.[Abstract/Free Full Text]

Jones, P. L., Schmidhauser, C. and Bissell, M. J (1993). Regulation of gene expression and cell function by extracellular matrix. Crit. Rev. Euk. Gene Expr 3, 137-154.[Medline]

Jones P. L., Boudreau, N., Myers, C. A., Erikson, H. P. and Bissell M. J (1995). Tenascin-C inhibits extracellular matrix-dependent gene expression in mammary epithelial cells. J. Cell Sci 108, 519-527.[Abstract]

Jones, P. L. and Rabinovitch, M (1996). Tenascin-C is induced with progressive pulmonary vascular disease in rats and is functionally related to increased smooth muscle cell proliferation. Circ. Res 79, 1131-1142.[Abstract/Free Full Text]

Jones, P., Cowan, L. and Rabinovitch, M (1997). Tenascin-C, prolifaeration and subendothelial fibronectin in progresive prulmonary vascular disease. Am. J. Path 150, 1349-1360.[Abstract]

Jones, P. L., Crack, J. and Rabinovitch, M (1997). Regulation of tenascin-C, a vascular smooth muscle cells survival factor that interacts with thev 3 integrin to promote epidermal growth factor receptor phosphorylation and growth. J. Cell Biol 139, 279-293.[Abstract/Free Full Text]

Juliano, R (1996). Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation. BioEssays 18, 911-911.[Medline]

Kageyama, R. and Pastan, I (1989). Molecular cloning and characterization of a human DNA binding factor that represses transcription. Cell 59, 815-825.[Medline]

Kheradmand, F., Werner, E., Tremble, P., Symons, M. and Werb Z (1998). Role of Rac1 and oxygen radicals in collagenase-1 expression induced by cell shape. Science 280, 898-902.[Abstract/Free Full Text]

Klemke, R. L., Cai, S., Giannini, A. L., Gallagher, P. J., de Lanerolle, P. and Cheresh, D. A (1997). Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol 137, 481-92.[Abstract/Free Full Text]

Koyama, H., Raines, E., Bornfeldt, K., Roberts, J. and Ross, R (1996). Fibrillar collagen inhbits arterial smooth muscle cell proliferation through regulation of Cdk2 inhibitors. Cell 87, 1069-1078.[Medline]

Krosl, J., Baban, S., Krosl, G., Rozenfeld, S., Largman, C. and Sauvageau, G (1998). Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1. Oncogene 16, 3403-3412.[Medline]

Mackie, E (1997). Molecules in focus: Tenascin-C. Int. J. Biochem. Cell Biol 29, 1133-1137.[Medline]

Maniero, F., Murgia, C., Wary, K. K., Curatola, A. M., Pepe, A., Blumberg, M., Westwick, J. K., Der, C. J. and Giancotti, F. G (1997). The coupling of6 4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation. EMBO J 16, 2365-2375.[Medline]

Messent, A. J., Tuckwell, D. S., Knauper, V., Humphries, M. J., Murphy, G. and Gavrilovic, J (1998). Effects of collagenase-cleavage of type I collagen on alpha2beta1 integrin-mediated cell adhesion. J. Cell Sci 111, 1127-1135.[Abstract]

Miano, J. M., Firulli, A. B., Olson, E. N., Hara, P., Giachelli, C. M. and Schwartz, S. M (1996). Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells. Proc. Natl. Acad. Sci. USA 93, 900-905.[Abstract/Free Full Text]

Miyamoto, S., Teramoto, H., Gutkind, J. S. and Yamada, K. M (1996). Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J. Cell Biol 135, 1633-1642.[Abstract/Free Full Text]

Montgomery, A., Reisfeld, R. and Cheresh, D (1994). Integrinv 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc. Natl. Acad. Sci. USA 91, 8856-8860.[Abstract/Free Full Text]

Mooney, D. J., Langer, R. and Ingber, D. E (1995). Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix. J. Cell Sci 108, 2311-2320.[Abstract]

Myers, C. A., Schmidhauser, C., Mellentin-Michelotti, J., Fragoso, G., Roskelley, C. D., Casperson, G., Mossi, R., Pujuguet, P., Hager, G. and Bissell, M. J (1998). Characterization of BCE-1, a transcriptional enhancer regulated by prolactin and extracellular matrix and modulated by the state of histone acetylation. Mol. Cell. Biol 18, 2184-2195.[Abstract/Free Full Text]

Nelson, H. C., Finch, J. T., Luisi, B. F. and Klug, A (1987). The structure of an oligo(dA).oligo(dT) tract and its biological implications. Nature 330, 221-226.[Medline]

Prieto, A., Edelman, G. and Crossin, K (1993). Multiple integrins mediate attachment to cytotactin/tenascin. Proc. Natl. Acad. Sci.USA 90, 10154-10158.[Abstract/Free Full Text]

Preissner, K., May, A., Wohn, K. Germer, M. and Kanse, S (1997). Molecular crosstalk between adhesion receptors and proteolytic cascades in vascular remodeling. Thromb. Haemostasis 78, 88-95.[Medline]

Rabinovitch, M (1997). Pulmonary hypertension: updating a mysterious disease. Card. Res 34, 268-272.[Free Full Text]

Reardon, B. J., Winters, R. S., Gordon, D. and Winter, E (1993). A peptide motif that recognizes A.T tracts in DNA. Proc. Natl. Acad. Sci. USA 90, 11327-11331.[Abstract/Free Full Text]

Renshaw, M. W., Ren, X. D. and Schwartz, M. A (1997). Growth factor activation of MAP kinase requires cell adhesion. EMBO J 16, 5592-5599.[Medline]

Schlaepfer, D. D., Hanks, S., Hunter, T. and van der Geer, P (1994). Integrin-mediated signal transduction linked to Ras pathway by Grb2 binding to focal adhesion kinase. Nature 372, 786-791.[Medline]

Slepian M., Mssia, S., Dehdashti, B., Fritz, A. and Whitesell, L (1998). Beta-3 integrins rather than beta-1 integrins dominate integrin-matrix interactions involved in postinjury smooth muscle cell migration. Circ 97, 1818-1827.[Abstract/Free Full Text]

Sriramarao, P., Mendler, M. and Bourdon, M (1993). Endothelial cell attachment and spreading on human tenascin is mediated by2 1 andv 3 integrins. J. Cell Sci 105, 1001-1012.[Abstract]

Srivatsa, S. S., Fitzpatrick L. A., Tsao, P. W., Reilly, T. M., Holmes, D. R. Jr., Schwartz, R. S. and Mousa, S. A (1997). Selective alpha v beta3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin alpha v beta 3 and osteopontin expression during neointima formation. Card. Res 36, 408-428.[Abstract/Free Full Text]

Stouffer, G., Hu, Z., Sajid, M., Li, H., Jin, G., Nakada M., Hanson S. andRunge, M (1998). Beta3 integrins are upregulated after vascular injury and modulate thrombosponsin and thrombin-induced proliferation of cultured smooth muscle cells. Circ 97, 907-915.[Abstract/Free Full Text]

Strauss, B., Robinson, R., Batchelor, W., Chisholm, R., Ravi, G., Natarajan, M., Logan, R., Mehta, S., Levy, D., Ezrin, A. and Keeley, F. W (1996). In vivo collagen turnover following experimental balloon angioplasty injury and the role of matrix metalloproteinases. Circ. Res 79, 541-550.[Abstract/Free Full Text]

Streuli, C. H. and Bissell, M. J (1990). Expression of extracellular matrix components is regulated by substratum. J. Cell Biol 110, 1405-1415.[Abstract/Free Full Text]

Tannenbaum, J. E., Waleh, N. S., Mauray, F., Breuss, J., Pytela. R., Kramer, R. H. and Clyman, R. I (1995). Transforming growth factor beta1 inhibits fetal lamb ductus arteriosus smooth muscle cell migration. Ped. Res 37, 561-570.[Medline]

Thyberg, J (1996). Differentiated properties and proliferation of arterial smooth muscle cells in culture. Int. Rev. Cytol 169, 183-265.[Medline]

Tuckwell, D. S. Ayad, S., Grant, M. E., Takigawa, M. and Humphries, M. J (1994). Conformation dependence of integrin-type II collagen binding. Inability of collagen peptides to support alpha 2 beta 1 binding, and mediation of adhesion to denatured collagen by a novel alpha 5 beta 1-fibronectin bridge. J. Cell Sci 107, 993-1005.[Abstract]

Weaver, V. M., Petersen, O. W., Wang, F., Larabell, C. A., Briand, P., Damsky, C. and Bissell, M. J (1997). Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol 137, 231-245.[Abstract/Free Full Text]

Yokosaki, Y., Monis, H., Chen, J. and Sheppard, D (1996). Differential effects of the integrins9 1,v 3 andv 6 on cell proliferative responses to tenascin. Roles of the Beta subunit extracellular and cytoplasmic domains. J. Biol. Chem 271, 24144-24150.[Abstract/Free Full Text]

Zempo, N., Kenagy, R., Bendeck, M., Clowes, M. and Reidy, M (1994). Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery. J. Vasc. Surg 20, 209-217.[Medline]

Zempo, N., Koyama N., Kenagy, R., Lea, H. and Clowes, A (1996). Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetc matrix metalloproteinase inhbitor. Arterio. Thromb. Vasc. Biol 16, 28-33.[Abstract/Free Full Text]

Zhou, B., Boudreau, N., Coulber, C., Hammarback, J. and Rabinovitch, M (1997). Microtubule-associated protein 1 light chain 3 is a fibronectin mRNA-binding protein linked to mRNA translation in lamb vascular smooth muscle cells. J. Clin. Invest 100, 3070-3082.[Medline]

Zhu, X. and Assoian, R. K (1995). Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation. Mol. Biol. Cell 6, 273-282.[Abstract]

This article has been cited by other articles:

A. Della Corte, C. Quarto, C. Bancone, C. Castaldo, F. Di Meglio, D. Nurzynska, L. S. De Santo, M. De Feo, M. Scardone, S. Montagnani, et al.
Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: Focus on cell matrix signaling
J. Thorac. Cardiovasc. Surg., January 1, 2008; 135(1): 8 - 18.
[Abstract] [Full Text] [PDF]

H. Y. Sung, H. Guan, A. Czibula, A. R. King, K. Eder, E. Heath, S. K. Suvarna, S. K. Dower, A. G. Wilson, S. E. Francis, et al.
Human Tribbles-1 Controls Proliferation and Chemotaxis of Smooth Muscle Cells via MAPK Signaling Pathways
J. Biol. Chem., June 22, 2007; 282(25): 18379 - 18387.
[Abstract] [Full Text] [PDF]

P. L. Jones
Move On!: Smooth Muscle Cell Motility Paired Down
Circ. Res., March 30, 2007; 100(6): 757 - 760.
[Full Text] [PDF]

A. Umesh, M. A. Thompson, E. N. Chini, K.-P. Yip, and J. S. K. Sham
Integrin Ligands Mobilize Ca2+ from Ryanodine Receptor-gated Stores and Lysosome-related Acidic Organelles in Pulmonary Arterial Smooth Muscle Cells
J. Biol. Chem., November 10, 2006; 281(45): 34312 - 34323.
[Abstract] [Full Text] [PDF]

R. Chapados, K. Abe, K. Ihida-Stansbury, D. McKean, A. T. Gates, M. Kern, S. Merklinger, J. Elliott, A. Plant, H. Shimokawa, et al.
ROCK Controls Matrix Synthesis in Vascular Smooth Muscle Cells: Coupling Vasoconstriction to Vascular Remodeling
Circ. Res., October 13, 2006; 99(8): 837 - 844.
[Abstract] [Full Text] [PDF]

K. Ihida-Stansbury, D. M. McKean, K. B. Lane, J. E. Loyd, L. A. Wheeler, N. W. Morrell, and P. L. Jones
Tenascin-C is induced by mutated BMP type II receptors in familial forms of pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol, October 1, 2006; 291(4): L694 - L702.
[Abstract] [Full Text] [PDF]

K. J. Aitken, G. Block, A. Lorenzo, D. Herz, N. Sabha, O. Dessouki, F. Fung, M. Szybowska, L. Craig, and D. J. Bagli
Mechanotransduction of Extracellular Signal-Regulated Kinases 1 and 2 Mitogen-Activated Protein Kinase Activity in Smooth Muscle Is Dependent on the Extracellular Matrix and Regulated by Matrix Metalloproteinases
Am. J. Pathol., August 1, 2006; 169(2): 459 - 470.
[Abstract] [Full Text] [PDF]

K. von Wnuck Lipinski, P. Keul, N. Ferri, S. Lucke, G. Heusch, J. W. Fischer, and B. Levkau
Integrin-Mediated Transcriptional Activation of Inhibitor of Apoptosis Proteins Protects Smooth Muscle Cells Against Apoptosis Induced by Degraded Collagen
Circ. Res., June 23, 2006; 98(12): 1490 - 1497.
[Abstract] [Full Text] [PDF]

K. von Wnuck Lipinski, P. Keul, S. Lucke, G. Heusch, J. Wohlschlaeger, H. A. Baba, and B. Levkau
Degraded collagen induces calpain-mediated apoptosis and destruction of the X-chromosome-linked inhibitor of apoptosis (xIAP) in human vascular smooth muscle cells
Cardiovasc Res, February 15, 2006; 69(3): 697 - 705.
[Abstract] [Full Text] [PDF]

S. L. Merklinger, P. L. Jones, E. C. Martinez, and M. Rabinovitch
Epidermal Growth Factor Receptor Blockade Mediates Smooth Muscle Cell Apoptosis and Improves Survival in Rats With Pulmonary Hypertension
Circulation, July 19, 2005; 112(3): 423 - 431.
[Abstract] [Full Text] [PDF]

S. Greenway, R. J. van Suylen, G. Du Marchie Sarvaas, E. Kwan, N. Ambartsumian, E. Lukanidin, and M. Rabinovitch
S100A4/Mts1 Produces Murine Pulmonary Artery Changes Resembling Plexogenic Arteriopathy and Is Increased in Human Plexogenic Arteriopathy
Am. J. Pathol., January 1, 2004; 164(1): 253 - 262.
[Abstract] [Full Text] [PDF]

T. Manes, D.-Q. Zheng, S. Tognin, A. S. Woodard, P. C. Marchisio, and L. R. Languino
{alpha}v{beta}3 integrin expression up-regulates cdc2, which modulates cell migration
J. Cell Biol., May 26, 2003; 161(4): 817 - 826.
[Abstract] [Full Text] [PDF]

D. M. McKean, L. Sisbarro, D. Ilic, N. Kaplan-Alburquerque, R. Nemenoff, M. Weiser-Evans, M. J. Kern, and P. L. Jones
FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration
J. Cell Biol., April 28, 2003; 161(2): 393 - 402.
[Abstract] [Full Text] [PDF]

R. Castellon, S. Caballero, H. K. Hamdi, S. R. Atilano, A. M. Aoki, R. W. Tarnuzzer, M. C. Kenney, M. B. Grant, and A. V. Ljubimov
Effects of Tenascin-C on Normal and Diabetic Retinal Endothelial Cells in Culture
Invest. Ophthalmol. Vis. Sci., August 1, 2002; 43(8): 2758 - 2766.
[Abstract] [Full Text] [PDF]

M. Wang and E. G. Lakatta
Altered Regulation of Matrix Metalloproteinase-2 in Aortic Remodeling During Aging
Hypertension, April 1, 2002; 39(4): 865 - 873.
[Abstract] [Full Text] [PDF]

P. L. Jones, R. Chapados, H. S. Baldwin, G. W. Raff, E. V. Vitvitsky, T. L. Spray, and J. W. Gaynor
Altered hemodynamics controls matrix metalloproteinase activity and tenascin-C expression in neonatal pig lung
Am J Physiol Lung Cell Mol Physiol, January 1, 2002; 282(1): L26 - L35.
[Abstract] [Full Text] [PDF]

B. Jian, P. L. Jones, Q. Li, E. R. Mohler III, F. J. Schoen, and R. J. Levy
Matrix Metalloproteinase-2 Is Associated with Tenascin-C in Calcific Aortic Stenosis
Am. J. Pathol., July 1, 2001; 159(1): 321 - 327.
[Abstract] [Full Text] [PDF]

C. Rescan, A. Coutant, H. Talarmin, N. Theret, D. Glaise, C. Guguen-Guillouzo, and G. Baffet
Mechanism in the Sequential Control of Cell Morphology and S Phase Entry by Epidermal Growth Factor Involves Distinct MEK/ERK Activations
Mol. Biol. Cell, March 1, 2001; 12(3): 725 - 738.
[Abstract] [Full Text]

N. Vyavahare, P. L. Jones, S. Tallapragada, and R. J. Levy
Inhibition of Matrix Metalloproteinase Activity Attenuates Tenascin-C Production and Calcification of Implanted Purified Elastin in Rats
Am. J. Pathol., September 1, 2000; 157(3): 885 - 893.
[Abstract] [Full Text] [PDF]

P. Babal, S. M. Manuel, J. W. Olson, and M. N. Gillespie
Cellular disposition of transported polyamines in hypoxic rat lung and pulmonary arteries
Am J Physiol Lung Cell Mol Physiol, March 1, 2000; 278(3): L610 - L617.
[Abstract] [Full Text] [PDF]

E Stringa, V Knauper, G Murphy, and J Gavrilovic
Collagen degradation and platelet-derived growth factor stimulate the migration of vascular smooth muscle cells
J. Cell Sci., January 6, 2000; 113(11): 2055 - 2064.
[Abstract] [PDF]

K. N. Cowan, P. L. Jones, and M. Rabinovitch
Regression of Hypertrophied Rat Pulmonary Arteries in Organ Culture Is Associated With Suppression of Proteolytic Activity, Inhibition of Tenascin-C, and Smooth Muscle Cell Apoptosis
Circ. Res., May 28, 1999; 84(10): 1223 - 1233.
[Abstract] [Full Text] [PDF]

F. S. Jones, R. Meech, D. B. Edelman, R. J. Oakey, and P. L. Jones
Prx1 Controls Vascular Smooth Muscle Cell Proliferation and Tenascin-C Expression and Is Upregulated With Prx2 in Pulmonary Vascular Disease
Circ. Res., July 20, 2001; 89(2): 131 - 138.
[Abstract] [Full Text] [PDF]

S. W. Galt, S. Lindemann, D. Medd, L. L. Allen, L. W. Kraiss, E. S. Harris, S. M. Prescott, T. M. McIntyre, A. S. Weyrich, and G. A. Zimmerman
Differential Regulation of Matrix Metalloproteinase-9 by Monocytes Adherent to Collagen and Platelets
Circ. Res., September 14, 2001; 89(6): 509 - 516.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Jones, P. L.

Articles by Rabinovitch, M.

Search for Related Content

PubMed

PubMed Citation

Articles by Jones, P. L.

Articles by Rabinovitch, M.

				H. Y. Sung, H. Guan, A. Czibula, A. R. King, K. Eder, E. Heath, S. K. Suvarna, S. K. Dower, A. G. Wilson, S. E. Francis, et al. Human Tribbles-1 Controls Proliferation and Chemotaxis of Smooth Muscle Cells via MAPK Signaling Pathways J. Biol. Chem., June 22, 2007; 282(25): 18379 - 18387. [Abstract] [Full Text] [PDF]

				P. L. Jones Move On!: Smooth Muscle Cell Motility Paired Down Circ. Res., March 30, 2007; 100(6): 757 - 760. [Full Text] [PDF]

				A. Umesh, M. A. Thompson, E. N. Chini, K.-P. Yip, and J. S. K. Sham Integrin Ligands Mobilize Ca2+ from Ryanodine Receptor-gated Stores and Lysosome-related Acidic Organelles in Pulmonary Arterial Smooth Muscle Cells J. Biol. Chem., November 10, 2006; 281(45): 34312 - 34323. [Abstract] [Full Text] [PDF]

				R. Chapados, K. Abe, K. Ihida-Stansbury, D. McKean, A. T. Gates, M. Kern, S. Merklinger, J. Elliott, A. Plant, H. Shimokawa, et al. ROCK Controls Matrix Synthesis in Vascular Smooth Muscle Cells: Coupling Vasoconstriction to Vascular Remodeling Circ. Res., October 13, 2006; 99(8): 837 - 844. [Abstract] [Full Text] [PDF]

				K. Ihida-Stansbury, D. M. McKean, K. B. Lane, J. E. Loyd, L. A. Wheeler, N. W. Morrell, and P. L. Jones Tenascin-C is induced by mutated BMP type II receptors in familial forms of pulmonary arterial hypertension Am J Physiol Lung Cell Mol Physiol, October 1, 2006; 291(4): L694 - L702. [Abstract] [Full Text] [PDF]

				K. J. Aitken, G. Block, A. Lorenzo, D. Herz, N. Sabha, O. Dessouki, F. Fung, M. Szybowska, L. Craig, and D. J. Bagli Mechanotransduction of Extracellular Signal-Regulated Kinases 1 and 2 Mitogen-Activated Protein Kinase Activity in Smooth Muscle Is Dependent on the Extracellular Matrix and Regulated by Matrix Metalloproteinases Am. J. Pathol., August 1, 2006; 169(2): 459 - 470. [Abstract] [Full Text] [PDF]

				K. von Wnuck Lipinski, P. Keul, N. Ferri, S. Lucke, G. Heusch, J. W. Fischer, and B. Levkau Integrin-Mediated Transcriptional Activation of Inhibitor of Apoptosis Proteins Protects Smooth Muscle Cells Against Apoptosis Induced by Degraded Collagen Circ. Res., June 23, 2006; 98(12): 1490 - 1497. [Abstract] [Full Text] [PDF]

				K. von Wnuck Lipinski, P. Keul, S. Lucke, G. Heusch, J. Wohlschlaeger, H. A. Baba, and B. Levkau Degraded collagen induces calpain-mediated apoptosis and destruction of the X-chromosome-linked inhibitor of apoptosis (xIAP) in human vascular smooth muscle cells Cardiovasc Res, February 15, 2006; 69(3): 697 - 705. [Abstract] [Full Text] [PDF]

				S. L. Merklinger, P. L. Jones, E. C. Martinez, and M. Rabinovitch Epidermal Growth Factor Receptor Blockade Mediates Smooth Muscle Cell Apoptosis and Improves Survival in Rats With Pulmonary Hypertension Circulation, July 19, 2005; 112(3): 423 - 431. [Abstract] [Full Text] [PDF]

				S. Greenway, R. J. van Suylen, G. Du Marchie Sarvaas, E. Kwan, N. Ambartsumian, E. Lukanidin, and M. Rabinovitch S100A4/Mts1 Produces Murine Pulmonary Artery Changes Resembling Plexogenic Arteriopathy and Is Increased in Human Plexogenic Arteriopathy Am. J. Pathol., January 1, 2004; 164(1): 253 - 262. [Abstract] [Full Text] [PDF]

				T. Manes, D.-Q. Zheng, S. Tognin, A. S. Woodard, P. C. Marchisio, and L. R. Languino {alpha}v{beta}3 integrin expression up-regulates cdc2, which modulates cell migration J. Cell Biol., May 26, 2003; 161(4): 817 - 826. [Abstract] [Full Text] [PDF]

				D. M. McKean, L. Sisbarro, D. Ilic, N. Kaplan-Alburquerque, R. Nemenoff, M. Weiser-Evans, M. J. Kern, and P. L. Jones FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration J. Cell Biol., April 28, 2003; 161(2): 393 - 402. [Abstract] [Full Text] [PDF]

				R. Castellon, S. Caballero, H. K. Hamdi, S. R. Atilano, A. M. Aoki, R. W. Tarnuzzer, M. C. Kenney, M. B. Grant, and A. V. Ljubimov Effects of Tenascin-C on Normal and Diabetic Retinal Endothelial Cells in Culture Invest. Ophthalmol. Vis. Sci., August 1, 2002; 43(8): 2758 - 2766. [Abstract] [Full Text] [PDF]

				M. Wang and E. G. Lakatta Altered Regulation of Matrix Metalloproteinase-2 in Aortic Remodeling During Aging Hypertension, April 1, 2002; 39(4): 865 - 873. [Abstract] [Full Text] [PDF]

				P. L. Jones, R. Chapados, H. S. Baldwin, G. W. Raff, E. V. Vitvitsky, T. L. Spray, and J. W. Gaynor Altered hemodynamics controls matrix metalloproteinase activity and tenascin-C expression in neonatal pig lung Am J Physiol Lung Cell Mol Physiol, January 1, 2002; 282(1): L26 - L35. [Abstract] [Full Text] [PDF]

				B. Jian, P. L. Jones, Q. Li, E. R. Mohler III, F. J. Schoen, and R. J. Levy Matrix Metalloproteinase-2 Is Associated with Tenascin-C in Calcific Aortic Stenosis Am. J. Pathol., July 1, 2001; 159(1): 321 - 327. [Abstract] [Full Text] [PDF]

				C. Rescan, A. Coutant, H. Talarmin, N. Theret, D. Glaise, C. Guguen-Guillouzo, and G. Baffet Mechanism in the Sequential Control of Cell Morphology and S Phase Entry by Epidermal Growth Factor Involves Distinct MEK/ERK Activations Mol. Biol. Cell, March 1, 2001; 12(3): 725 - 738. [Abstract] [Full Text]

				N. Vyavahare, P. L. Jones, S. Tallapragada, and R. J. Levy Inhibition of Matrix Metalloproteinase Activity Attenuates Tenascin-C Production and Calcification of Implanted Purified Elastin in Rats Am. J. Pathol., September 1, 2000; 157(3): 885 - 893. [Abstract] [Full Text] [PDF]

				P. Babal, S. M. Manuel, J. W. Olson, and M. N. Gillespie Cellular disposition of transported polyamines in hypoxic rat lung and pulmonary arteries Am J Physiol Lung Cell Mol Physiol, March 1, 2000; 278(3): L610 - L617. [Abstract] [Full Text] [PDF]

				E Stringa, V Knauper, G Murphy, and J Gavrilovic Collagen degradation and platelet-derived growth factor stimulate the migration of vascular smooth muscle cells J. Cell Sci., January 6, 2000; 113(11): 2055 - 2064. [Abstract] [PDF]

				K. N. Cowan, P. L. Jones, and M. Rabinovitch Regression of Hypertrophied Rat Pulmonary Arteries in Organ Culture Is Associated With Suppression of Proteolytic Activity, Inhibition of Tenascin-C, and Smooth Muscle Cell Apoptosis Circ. Res., May 28, 1999; 84(10): 1223 - 1233. [Abstract] [Full Text] [PDF]

				F. S. Jones, R. Meech, D. B. Edelman, R. J. Oakey, and P. L. Jones Prx1 Controls Vascular Smooth Muscle Cell Proliferation and Tenascin-C Expression and Is Upregulated With Prx2 in Pulmonary Vascular Disease Circ. Res., July 20, 2001; 89(2): 131 - 138. [Abstract] [Full Text] [PDF]

				S. W. Galt, S. Lindemann, D. Medd, L. L. Allen, L. W. Kraiss, E. S. Harris, S. M. Prescott, T. M. McIntyre, A. S. Weyrich, and G. A. Zimmerman Differential Regulation of Matrix Metalloproteinase-9 by Monocytes Adherent to Collagen and Platelets Circ. Res., September 14, 2001; 89(6): 509 - 516. [Abstract] [Full Text] [PDF]