The Ku70 autoantigen interacts with p40phox in B lymphocytes

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Abo, A., Boyhan, A., West, I., Thrasher, A. J. and Segal, A. W (1992). Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245. J. Biol. Chem 267, 16767-16770.[Abstract/Free Full Text]

Ajmani, A. K., Satoh, M., Reap, E., Cohen, P. L. and Reeves, W. H (1995). Absence of autoantigen Ku in mature human neutrophils and humanpromyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis. J. Exp. Med 181, 2049-2058.[Abstract/Free Full Text]

Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, D. J (1990). Basic local alignment search tool. J. Mol. Biol 215, 403-410.[Medline]

Anderson, C. W (1993). DNA damage and the DNA-activated protein kinase. Trends Biochem. Sci 18, 433-437.[Medline]

Aruffo, A. and Seed, B (1987). Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA 84, 8573-8577.[Abstract/Free Full Text]

Bandyopadhyay, D., Mandal, M., Adam, L., Mendelsohn, J. and Kumar, R (1998). Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells. J. Biol. Chem 273, 1568-1573.[Abstract/Free Full Text]

Bannister, A. J., Gottlieb, T. M., Kouzarides, T. and Jackson, S. P (1993). c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif. Nucleic Acids Res 21, 1289-1295.[Abstract/Free Full Text]

Barlev, N. A., Poltoratsky, V., Owen-Hughes, T., Ying, C., Liu, L., Workman, J. L. and Berger, S. L (1998). Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell Biol 18, 1349-1358.[Abstract/Free Full Text]

Blunt, T., Finnie, N. J., Taccioli, G. E., Smith, G. C., Demengeot, J., Gottlieb, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A., et al (1995). Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80, 813-823.[Medline]

Carter, T., Vancurova, I., Sun, I., Lou, W. and DeLeon, S (1990). A DNA-activated protein kinase from HeLa cell nuclei. Mol. Cell. Biol 10, 6460-6471.[Abstract/Free Full Text]

Chan, D. C., Bedford, M. T. and Leder, P (1996). Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J 15, 1045-1054.[Medline]

Cohen-Tanugi, L., Morel, F., Pilloud-Dagher, M. C., Seigneurin, J. M., Francois, P., Bost, M. and Vignais, P. V (1991). Activation of O2()-generating oxidase in an heterologous cell-free system derived from Epstein-Barr-virus-transformed human B lymphocytes and bovine neutrophils. Application to the study of defects in cytosolic factors in chronic granulomatous disease. Eur. J. Biochem 202, 649-655.[Medline]

Dvir, A., Stein, L. Y., Calore, B. L. and Dynan, W. S (1993). Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J. Biol. Chem 268, 10440-10447.[Abstract/Free Full Text]

Dynan, W. S. and Yoo, S (1998). Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res 26, 1551-1559.[Abstract/Free Full Text]

Einbond, A. and Sudol, M (1996). Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett 384, 1-8.[Medline]

Elango, N., Vivekananda, J., Strong, R. and Katz, M. S (1997). Nuclei isolation from bone cells for nuclear run-on assays. Biotechniques 23, 422-424.[Medline]

Estojak, J., Brent, R. and Golemis, E. A (1995). Correlation of two-hybrid affinity data with in vitro measurements. Mol. Cell. Biol 15, 5820-5829.[Abstract]

Falzon, M., Fewell, J. W. and Kuff, E. L (1993). EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single-to double-strand transitions in DNA. J. Biol. Chem 268, 10546-10552.[Abstract/Free Full Text]

Fewell, J. W. and Kuff, E. L (1996). Intracellular redistribution of Ku immunoreactivity in response to cell-cell contact and growth modulating components in the medium. J. Cell Sci 109, 1937-1946.[Abstract]

Fuchs, A., Bouin, A. P., Rabilloud, T. and Vignais, P. V (1997). The 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cells. Eur. J. Biochem 249, 531-539.[Medline]

Fuchs, A., Dagher, M. C., Faure, J. and Vignais, P. V (1996). Topological organization of the cytosolic activating complex of the superoxide-generating NADPH-oxidase. Pinpointing the sites of interaction between p47phoz, p67phox and p40phox using the two-hybrid system. Biochim. Biophys. Acta 1312, 39-47.[Medline]

Fuchs, A., Dagher, M. C., Jouan, A. and Vignais, P. V (1994). Activation of the O2()-generating NADPH oxidase in a semi-recombinant cell-free system. Assessment of the function of Rac in the activation process. Eur. J. Biochem 226, 587-595.[Medline]

Fuchs, A., Dagher, M. C. and Vignais, P. V (1995). Mapping the domains of interaction of p40phox with both p47phox and p67phox of the neutrophil oxidase complex using the two-hybrid system. J. Biol. Chem 270, 5695-5697.[Abstract/Free Full Text]

Giffin, W., Kwast-Welfeld, J., Rodda, D. J., Prefontaine, G. G., Traykova-Andonova, M., Zhang, Y., Weigel, N. L., Lefebvre, Y. A. and Hache, R. J (1997). Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J. Biol. Chem 272, 5647-5658.[Abstract/Free Full Text]

Giffin, W., Torrance, H., Rodda, D. J., Prefontaine, G. G., Pope, L. and Hache, R. J (1996). Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature 380, 265-268.[Medline]

Gottlieb, T. M. and Jackson, S. P (1993). The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131-142.[Medline]

Grawunder, U., Finnie, N., Jackson, S. P., Riwar, B. and Jessberger, R (1996). Expression of DNA-dependent protein kinase holoenzyme upon induction of lymphocyte differentiation and V(D)J recombination. Eur. J. Biochem 241, 931-940.[Medline]

Griffith, A. J., Blier, P. R., Mimori, T. and Hardin, J. A (1992). Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA. J. Biol. Chem 267, 331-338.[Abstract/Free Full Text]

Hammarsten, O. and Chu, G (1998). DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc. Natl. Acad. Sci. USA 95, 525-530.[Abstract/Free Full Text]

Hartley, K. O., Gell, D., Smith, G. C., Zhang, H., Divecha, N., Connelly, M. A., Admon, A., Lees-Miller, S. P., Anderson, C. W. and Jackson, S. P (1995). DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 82, 849-856.[Medline]

Henderson, L. M. and Chappel, J. B (1996). NADPH oxidase of neutrophils. Biochim. Biophys. Acta 1273, 87-107.[Medline]

Higashiura, M., Shimizu, Y., Tanimoto, M., Morita, T. and Yagura, T (1992). Immunolocalization of Ku-proteins (p80/p70): localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes. Exp. Cell Res 201, 444-451.[Medline]

Hollenberg, S. M., Sternglanz, R., Cheng, P. F. and Weintraub, H (1995). Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell Biol 15, 3813-3822.[Abstract]

Jackson, S. P. and Jeggo, P. A (1995). DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci 20, 412-415.[Medline]

Lees-Miller, S. P., Chen, Y. R. and Anderson, C. W (1990). Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol. Cell. Biol 10, 6472-6481.[Abstract/Free Full Text]

Lees-Miller, S. P., Godbout, R., Chan, D. W., Weinfeld, M., Day, R. S. R., Barron, G. M. and Allalunis-Turner, J (1995). Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 267, 1183-1185.[Abstract/Free Full Text]

Li, G. C., Yang, S. H., Kim, D., Nussenzweig, A., Ouyang, H., Wei, J., Burgman, P. and Li, L (1995). Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen. Proc. Natl. Acad. Sci. USA 92, 4512-4516.[Abstract/Free Full Text]

Maly, F. E., Cross, A. R., Jones, O. T., Wolf-Vorbeck, G., Walker, C., Dahinden, C. A. and De Weck, A. L (1988). The superoxide generating system of B cell lines. Structural homology with the phagocytic oxidase and triggering via surface Ig. J. Immunol 140, 2334-2339.[Abstract]

Mimori, T. and Hardin, J. A (1986). Mechanism of interaction between Ku protein and DNA. J. Biol. Chem 261, 10375-10379.[Abstract/Free Full Text]

Mizuki, K., Kadomatsu, K., Hata, K., Ito, T., Fan, Q. W., Kage, Y., Fukumaki, Y., Sakaki, Y., Takeshige, K. and Sumimoto, H (1998). Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex. Eur. J. Biochem 251, 573-582.[Medline]

Morel, F., Cohen Tanugi Cholley, L., Brandolin, G., Dianoux, A. C., Martel, C., Champelovier, P., Seigneurin, J. M., Francois, P., Bost, M. and Vignais, P. V (1993). The O2generating oxidase of B lymphocytes: Epstein-Barr virus-immortalized B lymphocytes as a tool for the identification of defective components of the oxidase in chronic granulomatous disease. Biochim. Biophys. Acta 1182, 101-109.[Medline]

Nakamura, R., Sumimoto, H., Mizuki, K., Hata, K., Ago, T., Kitajima, S., Takeshige, K., Sakaki, Y. and Ito, T (1998). The PC motif: a novel and evolutionarily conserved sequence involved in interaction between p40phox and p67phox, SH3 domain-containing cytosolic factors of the phagocyte NADPH oxidase. Eur. J. Biochem 251, 583-589.[Medline]

Ochem, A. E., Skopac, D., Costa, M., Rabilloud, T., Vuillard, L., Simoncsits, A., Giacca, M. and Falaschi, A (1997). Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen. J. Biol. Chem 272, 29919-29926.[Abstract/Free Full Text]

Ono, M., Tucker, P. W. and Capra, J. D (1996). Ku is a general inhibitor of DNA-protein complex formation and transcription. Mol. Immunol 33, 787-796.[Medline]

Reeves, W. H (1992). Antibodies to the p70/p80 (Ku) antigens in systemic lupus erythematosus. Rheum. Dis. Clin. North Am 18, 391-414.[Medline]

Romero, F., Dargemont, C., Pozo, F., Reeves, W. H., Camonis, J., Gisselbrecht, S. and Fischer, S (1996). p95vav associates with the nuclear protein Ku-70. Mol. Cell. Biol 16, 37-44.[Abstract]

Rotrosen, D., Yeung, C. L., Leto, T. L., Malech, H. L. and Kwong, C. H (1992). Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase. Science 256, 1459-1462.[Abstract/Free Full Text]

Sathyamoorthy, M., de Mendez, I., Adams, A. G. and Leto, T. L (1997). p40(phox) Down-regulates NADPH Oxidase Activity through Interactions with Its SH3 Domain. J. Biol. Chem 272, 9141-9146.[Abstract/Free Full Text]

Taccioli, G. E., Gottlieb, T. M., Blunt, T., Priestley, A., Demengeot, J., Mizuta, R., Lehmann, A. R., Alt, F. W., Jackson, S. P. and Jeggo, P. A (1994). Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265, 1442-1445.[Abstract/Free Full Text]

Thrasher, A. J., Keep, N. H., Wientjes, F. and Segal, A. W (1994). Chronic granulomatous disease. Biochim. Biophys. Acta 1227, 1-24.[Medline]

Tuteja, N., Tuteja, R., Ochem, A., Taneja, P., Huang, N. W., Simoncsits, A., Susic, S., Rahman, K., Marusic, L., Chen, J. and et al (1994). Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen. EMBO J 13, 4991-5001.[Medline]

Van Aelst, L., Barr, M., Marcus, S., Polverino, A. and Wigler, M (1993). Complex formation between RAS and RAF and other protein kinases. Proc. Natl. Acad. Sci. USA 90, 6213-6217.[Abstract/Free Full Text]

Vojtek, A. B., Hollenberg, S. M. and Cooper, J. A (1993). Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74, 205-214.[Medline]

Wen, W., Meinkoth, J. L., Tsien, R. Y. and Taylor, S. S (1995). Identification of a signal for rapid export of proteins from the nucleus. Cell 82, 463-473.[Medline]

Yaneva, M. and Jhiang, S (1991). Expression of the Ku protein during cell proliferation. Biochim. Biophys. Acta 1090, 181-187.[Medline]

Yaneva, M., Kowalewski, T. and Lieber, M. R (1997). Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J 16, 5098-5112.[Medline]

Yang, S. H., Nussenzweig, A., Li, L., Kim, D., Ouyang, H., Burgman, P. and Li, G. C (1996). Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits. Mol. Cell. Biol 16, 3799-3806.[Abstract]

Zhan, S., Vazquez, N., Zhan, S., Wientjes, F. B., Budarf, M. L., Schrock, E., Ried, T., Green, E. D. and Chanock, S. J (1996). Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex. Blood 88, 2714-2721.[Abstract/Free Full Text]

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				M. Geiszt NADPH oxidases: New kids on the block Cardiovasc Res, July 15, 2006; 71(2): 289 - 299. [Abstract] [Full Text] [PDF]

				C. Massenet, S. Chenavas, C. Cohen-Addad, M.-C. Dagher, G. Brandolin, E. Pebay-Peyroula, and F. Fieschi Effects of p47phox C Terminus Phosphorylations on Binding Interactions with p40phox and p67phox: STRUCTURAL AND FUNCTIONAL COMPARISON OF p40phox and p67phox SH3 DOMAINS J. Biol. Chem., April 8, 2005; 280(14): 13752 - 13761. [Abstract] [Full Text] [PDF]

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				K. D. Brown, T. A. Lataxes, S. Shangary, J. L. Mannino, J. F. Giardina, J. Chen, and R. Baskaran Ionizing Radiation Exposure Results in Up-regulation of Ku70 via a p53/Ataxia-Telangiectasia-mutated Protein-dependent Mechanism J. Biol. Chem., February 25, 2000; 275(9): 6651 - 6656. [Abstract] [Full Text] [PDF]