Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha

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				C. Paul, S. Teng, and P. T.K. Saunders A Single, Mild, Transient Scrotal Heat Stress Causes Hypoxia and Oxidative Stress in Mouse Testes, Which Induces Germ Cell Death Biol Reprod, May 1, 2009; 80(5): 913 - 919. [Abstract] [Full Text] [PDF]

				U. Berchner-Pfannschmidt, S. Frede, C. Wotzlaw, and J. Fandrey Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing Eur. Respir. J., July 1, 2008; 32(1): 210 - 217. [Abstract] [Full Text] [PDF]

				N. M. Romero, M. Irisarri, P. Roth, A. Cauerhff, C. Samakovlis, and P. Wappner Regulation of the Drosophila Hypoxia-Inducible Factor {alpha} Sima by CRM1-Dependent Nuclear Export Mol. Cell. Biol., May 15, 2008; 28(10): 3410 - 3423. [Abstract] [Full Text] [PDF]

				D. H. Shin, Y.-S. Chun, D. S. Lee, L. E. Huang, and J.-W. Park Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1 Blood, March 15, 2008; 111(6): 3131 - 3136. [Abstract] [Full Text] [PDF]

				P. A. Carroll, H. L. Kenerson, R. S. Yeung, and M. Lagunoff Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Activates Hypoxia-Induced Factors J. Virol., November 1, 2006; 80(21): 10802 - 10812. [Abstract] [Full Text] [PDF]

				H. Choi, Y.-S. Chun, S.-W. Kim, M.-S. Kim, and J.-W. Park Curcumin Inhibits Hypoxia-Inducible Factor-1 by Degrading Aryl Hydrocarbon Receptor Nuclear Translocator: A Mechanism of Tumor Growth Inhibition Mol. Pharmacol., November 1, 2006; 70(5): 1664 - 1671. [Abstract] [Full Text] [PDF]

				G. L. Semenza Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1 Exp Physiol, September 1, 2006; 91(5): 803 - 806. [Abstract] [Full Text] [PDF]

				D. P. Stiehl, R. Wirthner, J. Koditz, P. Spielmann, G. Camenisch, and R. H. Wenger Increased Prolyl 4-Hydroxylase Domain Proteins Compensate for Decreased Oxygen Levels: EVIDENCE FOR AN AUTOREGULATORY OXYGEN-SENSING SYSTEM J. Biol. Chem., August 18, 2006; 281(33): 23482 - 23491. [Abstract] [Full Text] [PDF]

				X. Zheng, J. L. Ruas, R. Cao, F. A. Salomons, Y. Cao, L. Poellinger, and T. Pereira Cell-Type-Specific Regulation of Degradation of Hypoxia-Inducible Factor 1{alpha}: Role of Subcellular Compartmentalization Mol. Cell. Biol., June 15, 2006; 26(12): 4628 - 4641. [Abstract] [Full Text] [PDF]

				H. Kim, H. Jeon, H. Kong, Y. Yang, B. Choi, Y. M. Kim, L. Neckers, and Y. Jung A Molecular Mechanism for the Anti-Inflammatory Effect of Taurine-Conjugated 5-Aminosalicylic Acid in Inflamed Colon Mol. Pharmacol., April 1, 2006; 69(4): 1405 - 1412. [Abstract] [Full Text] [PDF]

				E. B. Rankin, D. F. Higgins, J. A. Walisser, R. S. Johnson, C. A. Bradfield, and V. H. Haase Inactivation of the Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Suppresses von Hippel-Lindau Disease-Associated Vascular Tumors in Mice Mol. Cell. Biol., April 15, 2005; 25(8): 3163 - 3172. [Abstract] [Full Text] [PDF]

				K.-H. Lee, J.-W. Park, and Y.-S. Chun Non-hypoxic transcriptional activation of the aryl hydrocarbon receptor nuclear translocator in concert with a novel hypoxia-inducible factor-1alpha isoform Nucleic Acids Res., October 12, 2004; 32(18): 5499 - 5511. [Abstract] [Full Text] [PDF]

				G. Hopfl, O. Ogunshola, and M. Gassmann HIFs and tumors--causes and consequences Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2004; 286(4): R608 - R623. [Abstract] [Full Text] [PDF]

				M.A. Palladino, J.D. Powell, N. Korah, and L. Hermo Expression and Localization of Hypoxia-Inducible Factor-1 Subunits in the Adult Rat Epididymis Biol Reprod, April 1, 2004; 70(4): 1121 - 1130. [Abstract] [Full Text] [PDF]

				S. Welsh, R. Williams, L. Kirkpatrick, G. Paine-Murrieta, and G. Powis Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1{alpha} Mol. Cancer Ther., March 1, 2004; 3(3): 233 - 244. [Abstract] [Full Text]

				G. R. Macpherson, S. S.W. Ng, S. L. Forbes, G. Melillo, T. Karpova, J. McNally, T. P. Conrads, T. D. Veenstra, A. Martinez, F. Cuttitta, et al. Anti-angiogenic activity of human endostatin is HIF-1-independent in vitro and sensitive to timing of treatment in a human saphenous vein assay Mol. Cancer Ther., September 1, 2003; 2(9): 845 - 854. [Abstract] [Full Text] [PDF]

				A. Chauchereau, L. Amazit, M. Quesne, A. Guiochon-Mantel, and E. Milgrom Sumoylation of the Progesterone Receptor and of the Steroid Receptor Coactivator SRC-1 J. Biol. Chem., March 28, 2003; 278(14): 12335 - 12343. [Abstract] [Full Text] [PDF]

				I. Stolze, U. Berchner-Pfannschmidt, P. Freitag, C. Wotzlaw, J. Rossler, S. Frede, H. Acker, and J. Fandrey Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells Blood, September 18, 2002; 100(7): 2623 - 2628. [Abstract] [Full Text] [PDF]

				J. D. Powell, R. Elshtein, D. J. Forest, and M. A. Palladino Stimulation of Hypoxia-Inducible Factor-1 Alpha (HIF-1{alpha}) Protein in the Adult Rat Testis Following Ischemic Injury Occurs Without an Increase in HIF-1{alpha} Messenger RNA Expression Biol Reprod, September 1, 2002; 67(3): 995 - 1002. [Abstract] [Full Text] [PDF]

				R. H. WENGER Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression FASEB J, August 1, 2002; 16(10): 1151 - 1162. [Abstract] [Full Text] [PDF]

				N. Sang, J. Fang, V. Srinivas, I. Leshchinsky, and J. Caro Carboxyl-Terminal Transactivation Activity of Hypoxia-Inducible Factor 1{alpha} Is Governed by a von Hippel-Lindau Protein-Independent, Hydroxylation-Regulated Association with p300/CBP Mol. Cell. Biol., May 1, 2002; 22(9): 2984 - 2992. [Abstract] [Full Text] [PDF]

				G. Hopfl, R. H. Wenger, U. Ziegler, T. Stallmach, O. Gardelle, R. Achermann, M. Wergin, B. Kaser-Hotz, H. M. Saunders, K. J. Williams, et al. Rescue of Hypoxia-inducible Factor-1{alpha}-deficient Tumor Growth by Wild-Type Cells Is Independent of Vascular Endothelial Growth Factor Cancer Res., May 1, 2002; 62(10): 2962 - 2970. [Abstract] [Full Text] [PDF]

				A. M. Arsham, D. R. Plas, C. B. Thompson, and M. C. Simon Phosphatidylinositol 3-Kinase/Akt Signaling Is Neither Required for Hypoxic Stabilization of HIF-1alpha nor Sufficient for HIF-1-dependent Target Gene Transcription J. Biol. Chem., April 19, 2002; 277(17): 15162 - 15170. [Abstract] [Full Text] [PDF]

				Y.-S. Chun, E. Choi, E.-J. Yeo, J. H. Lee, M.-S. Kim, and J.-W. Park A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses J. Cell Sci., March 13, 2002; 114(22): 4051 - 4061. [Abstract] [Full Text] [PDF]

				D. M. Katschinski, L. Le, D. Heinrich, K. F. Wagner, T. Hofer, S. G. Schindler, and R. H. Wenger Heat Induction of the Unphosphorylated Form of Hypoxia-inducible Factor-1alpha Is Dependent on Heat Shock Protein-90 Activity J. Biol. Chem., March 8, 2002; 277(11): 9262 - 9267. [Abstract] [Full Text] [PDF]

				H. H. Marti, D. M. Katschinski, K. F. Wagner, L. Schaffer, B. Stier, and R. H. Wenger Isoform-Specific Expression of Hypoxia-Inducible Factor-1{alpha} During the Late Stages of Mouse Spermiogenesis Mol. Endocrinol., February 1, 2002; 16(2): 234 - 243. [Abstract] [Full Text] [PDF]

				B. Santiago-Josefat, E. Pozo-Guisado, S. Mulero-Navarro, and P. M. Fernandez-Salguero Proteasome Inhibition Induces Nuclear Translocation and Transcriptional Activation of the Dioxin Receptor in Mouse Embryo Primary Fibroblasts in the Absence of Xenobiotics Mol. Cell. Biol., March 1, 2001; 21(5): 1700 - 1709. [Abstract] [Full Text]

				R. M. Wanner, P. Spielmann, D. M. Stroka, G. Camenisch, I. Camenisch, A. Scheid, D. R. Houck, C. Bauer, M. Gassmann, and R. H. Wenger Epolones induce erythropoietin expression via hypoxia-inducible factor-1alpha activation Blood, August 15, 2000; 96(4): 1558 - 1565. [Abstract] [Full Text] [PDF]

				M. Garayoa, A. Martínez, S. Lee, R. Pío, W. G. An, L. Neckers, J. Trepel, L. M. Montuenga, H. Ryan, R. Johnson, et al. Hypoxia-Inducible Factor-1 (HIF-1) Up-Regulates Adrenomedullin Expression in Human Tumor Cell Lines during Oxygen Deprivation: A Possible Promotion Mechanism of Carcinogenesis Mol. Endocrinol., June 1, 2000; 14(6): 848 - 862. [Abstract] [Full Text]

				K. W. Braun, W. A. Tribley, M. D. Griswold, and K. H. Kim Follicle-stimulating Hormone Inhibits All-trans-retinoic Acid-induced Retinoic Acid Receptor alpha Nuclear Localization and Transcriptional Activation in Mouse Sertoli Cell Lines J. Biol. Chem., February 11, 2000; 275(6): 4145 - 4151. [Abstract] [Full Text] [PDF]