E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation

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A. E. Aplin, B. P. Hogan, J. Tomeu, and R. L. Juliano
Cell adhesion differentially regulates the nucleocytoplasmic distribution of active MAP kinases
J. Cell Sci., January 7, 2002; 115(13): 2781 - 2790.
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A. T. Ho, E. B. Voura, P. D. Soloway, K. L. M. Watson, and R. Khokha
MMP Inhibitors Augment Fibroblast Adhesion through Stabilization of Focal Adhesion Contacts and Up-regulation of Cadherin Function
J. Biol. Chem., October 19, 2001; 276(43): 40215 - 40224.
[Abstract] [Full Text] [PDF]

A. M. Carothers, K. A. Melstrom Jr., J. D. Mueller, M. J. Weyant, and M. M. Bertagnolli
Progressive Changes in Adherens Junction Structure during Intestinal Adenoma Formation in Apc Mutant Mice
J. Biol. Chem., October 12, 2001; 276(42): 39094 - 39102.
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A. Stockinger, A. Eger, J. Wolf, H. Beug, and R. Foisner
E-cadherin regulates cell growth by modulating proliferation-dependent {beta}-catenin transcriptional activity
J. Cell Biol., September 17, 2001; 154(6): 1185 - 1196.
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J. Sussman, D. Stokoe, N. Ossina, and E. Shtivelman
Protein kinase B phosphorylates AHNAK and regulates its subcellular localization
J. Cell Biol., September 3, 2001; 154(5): 1019 - 1030.
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A. E. Aplin, S. A. Stewart, R. K. Assoian, and R.L. Juliano
Integrin-mediated adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1
J. Cell Biol., April 9, 2001; 153(2): 273 - 282.
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P Goichberg, M Shtutman, A Ben-Ze'ev, and B Geiger
Recruitment of (&bgr;)-catenin to cadherin-mediated intercellular adhesions is involved in myogenic induction
J. Cell Sci., January 4, 2001; 114(7): 1309 - 1319.
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A Somasiri, A Howarth, D Goswami, S Dedhar, and C. Roskelley
Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells
J. Cell Sci., January 3, 2001; 114(6): 1125 - 1136.
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M. van de Wetering, N. Barker, I. C. Harkes, M. van der Heyden, N. J. Dijk, A. Hollestelle, J. G. M. Klijn, H. Clevers, and M. Schutte
Mutant E-cadherin Breast Cancer Cells Do Not Display Constitutive Wnt Signaling
Cancer Res., January 1, 2001; 61(1): 278 - 284.
[Abstract] [Full Text]

V Noe, B Fingleton, K Jacobs, H. Crawford, S Vermeulen, W Steelant, E Bruyneel, L. Matrisian, and M Mareel
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
J. Cell Sci., January 1, 2001; 114(1): 111 - 118.
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C. Y. Sasaki, H. Lin, P. J. Morin, and D. L. Longo
Truncation of the Extracellular Region Abrogrates Cell Contact but Retains the Growth-suppressive Activity of E-cadherin
Cancer Res., December 1, 2000; 60(24): 7057 - 7065.
[Abstract] [Full Text]

U Kaufmann, C Zuppinger, Z Waibler, M Rudiger, C Urbich, B Martin, B. Jockusch, H Eppenberger, and A Starzinski-Powitz
The armadillo repeat region targets ARVCF to cadherin-based cellular junctions
J. Cell Sci., January 11, 2000; 113(22): 4121 - 4135.
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A. Eger, A. Stockinger, B. Schaffhauser, H. Beug, and R. Foisner
Epithelial Mesenchymal Transition by c-Fos Estrogen Receptor Activation Involves Nuclear Translocation of {beta}-Catenin and Upregulation of {beta}-Catenin/Lymph

				A. Badde and D. Schulte A Role for Receptor Protein Tyrosine Phosphatase {lambda} in Midbrain Development J. Neurosci., June 11, 2008; 28(24): 6152 - 6164. [Abstract] [Full Text] [PDF]

				W.-H. Lien, O. Klezovitch, M. Null, and V. Vasioukhin {alpha}E-catenin is not a significant regulator of {beta}-catenin signaling in the developing mammalian brain J. Cell Sci., May 1, 2008; 121(9): 1357 - 1362. [Abstract] [Full Text] [PDF]

				P. Ortega, A. Moran, C. de Juan, C. Frias, S. Hernandez, J.-A. Lopez-Asenjo, A. Sanchez-Pernaute, A. Torres, P. Iniesta, and M. Benito Differential Wnt Pathway Gene Expression and E-Cadherin Truncation in Sporadic Colorectal Cancers with and without Microsatellite Instability Clin. Cancer Res., February 15, 2008; 14(4): 995 - 1001. [Abstract] [Full Text] [PDF]

				T. Ezaki, R.-J. Guo, H. Li, A. B. Reynolds, and J. P. Lynch The homeodomain transcription factors Cdx1 and Cdx2 induce E-cadherin adhesion activity by reducing beta- and p120-catenin tyrosine phosphorylation Am J Physiol Gastrointest Liver Physiol, July 1, 2007; 293(1): G54 - G65. [Abstract] [Full Text] [PDF]

				M. Toyoshima, N. Tanaka, J. Aoki, Y. Tanaka, K. Murata, M. Kyuuma, H. Kobayashi, N. Ishii, N. Yaegashi, and K. Sugamura Inhibition of Tumor Growth and Metastasis by Depletion of Vesicular Sorting Protein Hrs: Its Regulatory Role on E-Cadherin and {beta}-Catenin Cancer Res., June 1, 2007; 67(11): 5162 - 5171. [Abstract] [Full Text] [PDF]

				M. Perrais, X. Chen, M. Perez-Moreno, and B. M. Gumbiner E-Cadherin Homophilic Ligation Inhibits Cell Growth and Epidermal Growth Factor Receptor Signaling Independently of Other Cell Interactions Mol. Biol. Cell, June 1, 2007; 18(6): 2013 - 2025. [Abstract] [Full Text] [PDF]

				B. Humar, R. Fukuzawa, V. Blair, A. Dunbier, H. More, A. Charlton, H. K. Yang, W. H. Kim, A. E. Reeve, I. Martin, et al. Destabilized Adhesion in the Gastric Proliferative Zone and c-Src Kinase Activation Mark the Development of Early Diffuse Gastric Cancer Cancer Res., March 15, 2007; 67(6): 2480 - 2489. [Abstract] [Full Text] [PDF]

				Y. L. Pon and A. S. T. Wong Gonadotropin-Induced Apoptosis in Human Ovarian Surface Epithelial Cells Is Associated with Cyclooxygenase-2 Up-Regulation via the {beta}-Catenin/T-Cell Factor Signaling Pathway Mol. Endocrinol., December 1, 2006; 20(12): 3336 - 3350. [Abstract] [Full Text] [PDF]

				R. Hou, L. Liu, S. Anees, S. Hiroyasu, and N. E.S. Sibinga The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals J. Cell Biol., May 8, 2006; 173(3): 417 - 429. [Abstract] [Full Text] [PDF]

				E. Krieghoff, J. Behrens, and B. Mayr Nucleo-cytoplasmic distribution of {beta}-catenin is regulated by retention. J. Cell Sci., April 1, 2006; 119(Pt 7): 1453 - 1463. [Abstract] [Full Text] [PDF]

				X. Wu, F. Quondamatteo, T. Lefever, A. Czuchra, H. Meyer, A. Chrostek, R. Paus, L. Langbein, and C. Brakebusch Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. Genes & Dev., March 1, 2006; 20(5): 571 - 585. [Abstract] [Full Text] [PDF]

				H. Andersen, J. Mejlvang, S. Mahmood, I. Gromova, P. Gromov, E. Lukanidin, M. Kriajevska, J. K. Mellon, and E. Tulchinsky Immediate and Delayed Effects of E-Cadherin Inhibition on Gene Regulation and Cell Motility in Human Epidermoid Carcinoma Cells Mol. Cell. Biol., October 15, 2005; 25(20): 9138 - 9150. [Abstract] [Full Text] [PDF]

				C. J. Gottardi and B. M. Gumbiner Distinct molecular forms of {beta}-catenin are targeted to adhesive or transcriptional complexes J. Cell Biol., October 25, 2004; 167(2): 339 - 349. [Abstract] [Full Text] [PDF]

				R.-J. Guo, E. Huang, T. Ezaki, N. Patel, K. Sinclair, J. Wu, P. Klein, E.-R. Suh, and J. P. Lynch Cdx1 Inhibits Human Colon Cancer Cell Proliferation by Reducing {beta}-Catenin/T-cell Factor Transcriptional Activity J. Biol. Chem., August 27, 2004; 279(35): 36865 - 36875. [Abstract] [Full Text] [PDF]

				M. S. Keller, T. Ezaki, R.-J. Guo, and J. P. Lynch Cdx1 or Cdx2 expression activates E-cadherin-mediated cell-cell adhesion and compaction in human COLO 205 cells Am J Physiol Gastrointest Liver Physiol, July 1, 2004; 287(1): G104 - G114. [Abstract] [Full Text] [PDF]

				C. H. M. Castro, C. S. Shin, J. P. Stains, S.-L. Cheng, S. Sheikh, G. Mbalaviele, V. L. Szejnfeld, and R. Civitelli Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis J. Cell Sci., June 1, 2004; 117(13): 2853 - 2864. [Abstract] [Full Text] [PDF]

				N. A. Graham and A. R. Asthagiri Epidermal Growth Factor-mediated T-cell Factor/Lymphoid Enhancer Factor Transcriptional Activity Is Essential but Not Sufficient for Cell Cycle Progression in Nontransformed Mammary Epithelial Cells J. Biol. Chem., May 28, 2004; 279(22): 23517 - 23524. [Abstract] [Full Text] [PDF]

				B. H. Hoang, T. Kubo, J. H. Healey, R. Yang, S. S. Nathan, E. A. Kolb, B. Mazza, P. A. Meyers, and R. Gorlick Dickkopf 3 Inhibits Invasion and Motility of Saos-2 Osteosarcoma Cells by Modulating the Wnt-{beta}-Catenin Pathway Cancer Res., April 15, 2004; 64(8): 2734 - 2739. [Abstract] [Full Text] [PDF]

				C. J. Gottardi and B. M. Gumbiner Role for ICAT in {beta}-catenin-dependent nuclear signaling and cadherin functions Am J Physiol Cell Physiol, April 1, 2004; 286(4): C747 - C756. [Abstract] [Full Text] [PDF]

				M. C. Faux, J. L. Ross, C. Meeker, T. Johns, H. Ji, R. J. Simpson, M. J. Layton, and A. W. Burgess Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion J. Cell Sci., January 22, 2004; 117(3): 427 - 439. [Abstract] [Full Text] [PDF]

				N. K. Veeramachaneni, H. Kubokura, L. Lin, J. A. Pippin, G. A. Patterson, J. A. Drebin, and R. J. Battafarano Down-regulation of beta catenin inhibits the growth of esophageal carcinoma cells J. Thorac. Cardiovasc. Surg., January 1, 2004; 127(1): 92 - 98. [Abstract] [Full Text] [PDF]

				Y. Guan, N. M. Rubenstein, K. L. Failor, P. L. Woo, and G. L. Firestone Glucocorticoids Control {beta}-Catenin Protein Expression and Localization through Distinct Pathways that Can Be Uncoupled by Disruption of Signaling Events Required for Tight Junction Formation in Rat Mammary Epithelial Tumor Cells Mol. Endocrinol., January 1, 2004; 18(1): 214 - 227. [Abstract] [Full Text] [PDF]

				D. Okamura, T. Kimura, T. Nakano, and Y. Matsui Cadherin-mediated cell interaction regulates germ cell determination in mice Development, December 29, 2003; 130(26): 6423 - 6430. [Abstract] [Full Text] [PDF]

				J. Sanceau, S. Truchet, and B. Bauvois Matrix Metalloproteinase-9 Silencing by RNA Interference Triggers the Migratory-adhesive Switch in Ewing's Sarcoma Cells J. Biol. Chem., September 19, 2003; 278(38): 36537 - 36546. [Abstract] [Full Text] [PDF]

				B. J. Katafiasz, M. T. Nieman, M. J. Wheelock, and K. R. Johnson Characterization of Cadherin-24, a Novel Alternatively Spliced Type II Cadherin J. Biol. Chem., July 18, 2003; 278(30): 27513 - 27519. [Abstract] [Full Text] [PDF]

				J. Piedra, S. Miravet, J. Castano, H. G. Palmer, N. Heisterkamp, A. Garcia de Herreros, and M. Dunach p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate {beta}-Catenin Tyr-142 Phosphorylation and {beta}-Catenin-{alpha}-Catenin Interaction Mol. Cell. Biol., April 1, 2003; 23(7): 2287 - 2297. [Abstract] [Full Text] [PDF]

				J. Gotoh, M. Obata, M. Yoshie, S. Kasai, and K. Ogawa Cyclin D1 over-expression correlates with {beta}-catenin activation, but not with H-ras mutations, and phosphorylation of Akt, GSK3{beta} and ERK1/2 in mouse hepatic carcinogenesis Carcinogenesis, March 1, 2003; 24(3): 435 - 442. [Abstract] [Full Text] [PDF]

				G. Li and R. Iyengar Calpain as an effector of the Gq signaling pathway for inhibition of Wnt/beta -catenin-regulated cell proliferation PNAS, October 1, 2002; 99(20): 13254 - 13259. [Abstract] [Full Text] [PDF]

				M. S. Lee, K. A. D'Amour, and J. Papkoff A yeast model system for functional analysis of {beta}-catenin signaling J. Cell Biol., September 16, 2002; 158(6): 1067 - 1078. [Abstract] [Full Text] [PDF]

				R. DasGupta, H. Rhee, and E. Fuchs A developmental conundrum: a stabilized form of {beta}-catenin lacking the transcriptional activation domain triggers features of hair cell fate in epidermal cells and epidermal cell fate in hair follicle cells J. Cell Biol., July 22, 2002; 158(2): 331 - 344. [Abstract] [Full Text] [PDF]