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Q. Chen, H. Kimura, and D. Schubert A novel mechanism for the regulation of amyloid precursor protein metabolism J. Cell Biol., July 8, 2002; 158(1): 79 - 89. [Abstract] [Full Text] [PDF] |
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P. E. Tarr, R. Roncarati, G. Pelicci, P. G. Pelicci, and L. D'Adamio Tyrosine Phosphorylation of the beta -Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc J. Biol. Chem., May 3, 2002; 277(19): 16798 - 16804. [Abstract] [Full Text] [PDF] |
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N. Kawaguchi, X. Xu, R. Tajima, P. Kronqvist, C. Sundberg, F. Loechel, R. Albrechtsen, and U. M. Wewer ADAM 12 Protease Induces Adipogenesis in Transgenic Mice Am. J. Pathol., May 1, 2002; 160(5): 1895 - 1903. [Abstract] [Full Text] [PDF] |
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Q. Hu, B. H. Cool, B. Wang, M. G. Hearn, and G. M. Martin A candidate molecular mechanism for the association of an intronic polymorphism of FE65 with resistance to very late onset dementia of the Alzheimer type Hum. Mol. Genet., February 1, 2002; 11(4): 465 - 475. [Abstract] [Full Text] [PDF] |
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S. F. Lichtenthaler, D. Beher, H. S. Grimm, R. Wang, M. S. Shearman, C. L. Masters, and K. Beyreuther The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain PNAS, January 17, 2002; (2002) 32395699. [Abstract] [Full Text] [PDF] |
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N. Zambrano, M. Bimonte, S. Arbucci, D. Gianni, T. Russo, and P. Bazzicalupo feh-1 and apl-1, the Caenorhabditis elegans orthologues of mammalian Fe65 and {beta}-amyloid precursor protein genes, are involved in the same pathway that controls nematode pharyngeal pumping J. Cell Sci., January 4, 2002; 115(7): 1411 - 1422. [Abstract] [Full Text] [PDF] |
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Y. Gao and S. W. Pimplikar The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus PNAS, December 6, 2001; (2001) 261463298. [Abstract] [Full Text] [PDF] |
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A. Kinoshita, C. M. Whelan, C. J. Smith, I. Mikhailenko, G. W. Rebeck, D. K. Strickland, and B. T. Hyman Demonstration by Fluorescence Resonance Energy Transfer of Two Sites of Interaction between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein: Role of the Intracellular Adapter Protein Fe65 J. Neurosci., November 1, 2001; 21(21): 8354 - 8361. [Abstract] [Full Text] [PDF] |
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W. T. Kimberly, J. B. Zheng, S. Y. Guenette, and D. J. Selkoe The Intracellular Domain of the beta -Amyloid Precursor Protein Is Stabilized by Fe65 and Translocates to the Nucleus in a Notch-like Manner J. Biol. Chem., October 19, 2001; 276(43): 40288 - 40292. [Abstract] [Full Text] [PDF] |
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L. S. B. Goldstein Kinesin molecular motors: Transport pathways, receptors, and human disease PNAS, June 19, 2001; 98(13): 6999 - 7003. [Abstract] [Full Text] [PDF] |
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S. B. Prusiner Neurodegenerative Diseases and Prions N. Engl. J. Med., May 17, 2001; 344(20): 1516 - 1526. [Full Text] [PDF] |
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R. Kopan and A. Goate A common enzyme connects Notch signaling and Alzheimer's disease Genes & Dev., November 15, 2000; 14(22): 2799 - 2806. [Full Text] |
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G. Minopoli, P. de Candia, A. Bonetti, R. Faraonio, N. Zambrano, and T. Russo The beta -Amyloid Precursor Protein Functions as a Cytosolic Anchoring Site That Prevents Fe65 Nuclear Translocation J. Biol. Chem., February 23, 2001; 276(9): 6545 - 6550. [Abstract] [Full Text] [PDF] |
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H. Iwata, T. Tomita, K. Maruyama, and T. Iwatsubo Subcellular Compartment and Molecular Subdomain of beta -Amyloid Precursor Protein Relevant to the Abeta 42-promoting Effects of Alzheimer Mutant Presenilin 2 J. Biol. Chem., June 8, 2001; 276(24): 21678 - 21685. [Abstract] [Full Text] [PDF] |
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O. Berezovska, C. Jack, A. Deng, N. Gastineau, G. W. Rebeck, and B. T. Hyman Notch1 and Amyloid Precursor Protein Are Competitive Substrates for Presenilin1-dependent gamma -Secretase Cleavage J. Biol. Chem., August 3, 2001; 276(32): 30018 - 30023. [Abstract] [Full Text] [PDF] |
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H. T. Mueller, J.-P. Borg, B. Margolis, and R. S. Turner Modulation of Amyloid Precursor Protein Metabolism by X11alpha /Mint-1. A DELETION ANALYSIS OF PROTEIN-PROTEIN INTERACTION DOMAINS J. Biol. Chem., December 8, 2000; 275(50): 39302 - 39306. [Abstract] [Full Text] [PDF] |
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S. F. Lichtenthaler, D. Beher, H. S. Grimm, R. Wang, M. S. Shearman, C. L. Masters, and K. Beyreuther The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain PNAS, February 5, 2002; 99(3): 1365 - 1370. [Abstract] [Full Text] [PDF] |
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E. Kojro, G. Gimpl, S. Lammich, W. Marz, and F. Fahrenholz From the Cover: Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10 PNAS, May 8, 2001; 98(10): 5815 - 5820. [Abstract] [Full Text] [PDF] |
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Y. Gao and S. W. Pimplikar The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus PNAS, December 18, 2001; 98(26): 14979 - 14984. [Abstract] [Full Text] [PDF] |
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