Proteolytic processing and cell biological functions of the amyloid precursor protein

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I.-S. Yoon, E. Chen, T. Busse, E. Repetto, M. K. Lakshmana, E. H. Koo, and D. E. Kang
Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway
FASEB J, September 1, 2007; 21(11): 2742 - 2752.
[Abstract] [Full Text] [PDF]

A. Ma, M. Boulton, B. Zhao, C. Connon, J. Cai, and J. Albon
A Role for Notch Signaling in Human Corneal Epithelial Cell Differentiation and Proliferation
Invest. Ophthalmol. Vis. Sci., August 1, 2007; 48(8): 3576 - 3585.
[Abstract] [Full Text] [PDF]

A. Marutle, M. Ohmitsu, M. Nilbratt, N. H. Greig, A. Nordberg, and K. Sugaya
Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine
PNAS, July 24, 2007; 104(30): 12506 - 12511.
[Abstract] [Full Text] [PDF]

P. Satpute-Krishnan, J. A. DeGiorgis, M. P. Conley, M. Jang, and E. L. Bearer
A peptide zipcode sufficient for anterograde transport within amyloid precursor protein
PNAS, October 31, 2006; 103(44): 16532 - 16537.
[Abstract] [Full Text] [PDF]

Z. Muresan and V. Muresan
Neuritic Deposits of Amyloid-{beta} Peptide in a Subpopulation of Central Nervous System-Derived Neuronal Cells.
Mol. Cell. Biol., July 1, 2006; 26(13): 4982 - 4997.
[Abstract] [Full Text] [PDF]

B. A. Tate and P. M. Mathews
Targeting the Role of the Endosome in the Pathophysiology of Alzheimer's Disease: A Strategy for Treatment
Sci. Aging Knowl. Environ., June 28, 2006; 2006(10): re2 - re2.
[Abstract] [Full Text] [PDF]

T. E. Willnow and O. M. Andersen
Pin-pointing APP Processing
Mol. Interv., June 1, 2006; 6(3): 137 - 139.
[Abstract] [Full Text] [PDF]

M. Ahmad, T. Takino, H. Miyamori, T. Yoshizaki, M. Furukawa, and H. Sato
Cleavage of Amyloid-{beta} Precursor Protein (APP) by Membrane-Type Matrix Metalloproteinases.
J. Biochem., March 1, 2006; 139(3): 517 - 526.
[Abstract] [Full Text] [PDF]

L. Kalvodova, N. Kahya, P. Schwille, R. Ehehalt, P. Verkade, D. Drechsel, and K. Simons
Lipids as Modulators of Proteolytic Activity of BACE: INVOLVEMENT OF CHOLESTEROL, GLYCOSPHINGOLIPIDS, AND ANIONIC PHOSPHOLIPIDS IN VITRO
J. Biol. Chem., November 4, 2005; 280(44): 36815 - 36823.
[Abstract] [Full Text] [PDF]

K. A. Ryan and S. W. Pimplikar
Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain
J. Cell Biol., October 24, 2005; 171(2): 327 - 335.
[Abstract] [Full Text] [PDF]

O. M. Andersen, J. Reiche, V. Schmidt, M. Gotthardt, R. Spoelgen, J. Behlke, C. A. F. von Arnim, T. Breiderhoff, P. Jansen, X. Wu, et al.
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
PNAS, September 20, 2005; 102(38): 13461 - 13466.
[Abstract] [Full Text] [PDF]

Z. Muresan and V. Muresan
c-Jun NH2-Terminal Kinase-Interacting Protein-3 Facilitates Phosphorylation and Controls Localization of Amyloid-{beta} Precursor Protein
J. Neurosci., April 13, 2005; 25(15): 3741 - 3751.
[Abstract] [Full Text] [PDF]

A. B. Reiss
Cholesterol and a

				R. A. Nixon Autophagy, amyloidogenesis and Alzheimer disease J. Cell Sci., December 1, 2007; 120(23): 4081 - 4091. [Abstract] [Full Text] [PDF]

				V. Schmidt, A. Sporbert, M. Rohe, T. Reimer, A. Rehm, O. M. Andersen, and T. E. Willnow SorLA/LR11 Regulates Processing of Amyloid Precursor Protein via Interaction with Adaptors GGA and PACS-1 J. Biol. Chem., November 9, 2007; 282(45): 32956 - 32964. [Abstract] [Full Text] [PDF]

				M. S. Wolfe and S. Y. Guenette APP at a glance J. Cell Sci., September 15, 2007; 120(18): 3157 - 3161. [Full Text] [PDF]

				I.-S. Yoon, E. Chen, T. Busse, E. Repetto, M. K. Lakshmana, E. H. Koo, and D. E. Kang Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway FASEB J, September 1, 2007; 21(11): 2742 - 2752. [Abstract] [Full Text] [PDF]

				A. Ma, M. Boulton, B. Zhao, C. Connon, J. Cai, and J. Albon A Role for Notch Signaling in Human Corneal Epithelial Cell Differentiation and Proliferation Invest. Ophthalmol. Vis. Sci., August 1, 2007; 48(8): 3576 - 3585. [Abstract] [Full Text] [PDF]

				A. Marutle, M. Ohmitsu, M. Nilbratt, N. H. Greig, A. Nordberg, and K. Sugaya Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine PNAS, July 24, 2007; 104(30): 12506 - 12511. [Abstract] [Full Text] [PDF]

				P. Satpute-Krishnan, J. A. DeGiorgis, M. P. Conley, M. Jang, and E. L. Bearer A peptide zipcode sufficient for anterograde transport within amyloid precursor protein PNAS, October 31, 2006; 103(44): 16532 - 16537. [Abstract] [Full Text] [PDF]

				Z. Muresan and V. Muresan Neuritic Deposits of Amyloid-{beta} Peptide in a Subpopulation of Central Nervous System-Derived Neuronal Cells. Mol. Cell. Biol., July 1, 2006; 26(13): 4982 - 4997. [Abstract] [Full Text] [PDF]

				B. A. Tate and P. M. Mathews Targeting the Role of the Endosome in the Pathophysiology of Alzheimer's Disease: A Strategy for Treatment Sci. Aging Knowl. Environ., June 28, 2006; 2006(10): re2 - re2. [Abstract] [Full Text] [PDF]

				T. E. Willnow and O. M. Andersen Pin-pointing APP Processing Mol. Interv., June 1, 2006; 6(3): 137 - 139. [Abstract] [Full Text] [PDF]

				M. Ahmad, T. Takino, H. Miyamori, T. Yoshizaki, M. Furukawa, and H. Sato Cleavage of Amyloid-{beta} Precursor Protein (APP) by Membrane-Type Matrix Metalloproteinases. J. Biochem., March 1, 2006; 139(3): 517 - 526. [Abstract] [Full Text] [PDF]

				L. Kalvodova, N. Kahya, P. Schwille, R. Ehehalt, P. Verkade, D. Drechsel, and K. Simons Lipids as Modulators of Proteolytic Activity of BACE: INVOLVEMENT OF CHOLESTEROL, GLYCOSPHINGOLIPIDS, AND ANIONIC PHOSPHOLIPIDS IN VITRO J. Biol. Chem., November 4, 2005; 280(44): 36815 - 36823. [Abstract] [Full Text] [PDF]

				K. A. Ryan and S. W. Pimplikar Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain J. Cell Biol., October 24, 2005; 171(2): 327 - 335. [Abstract] [Full Text] [PDF]

				O. M. Andersen, J. Reiche, V. Schmidt, M. Gotthardt, R. Spoelgen, J. Behlke, C. A. F. von Arnim, T. Breiderhoff, P. Jansen, X. Wu, et al. Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein PNAS, September 20, 2005; 102(38): 13461 - 13466. [Abstract] [Full Text] [PDF]

				Z. Muresan and V. Muresan c-Jun NH2-Terminal Kinase-Interacting Protein-3 Facilitates Phosphorylation and Controls Localization of Amyloid-{beta} Precursor Protein J. Neurosci., April 13, 2005; 25(15): 3741 - 3751. [Abstract] [Full Text] [PDF]