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Arama, E., Yanai, A., Kilfin, G., Bernstein, A. and Motro, B (1998). Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system. Oncogene 16, 1813-1823.[Medline]

Archer, J. and Solomon, F (1994). Deconstructing the microtubule-organizing center. Cell 76, 589-591.[Medline]

Barton, A. B., Davies, C. J., Hutchison, C. A. D. and Kaback, D. B (1992). Cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the FUN52 gene, whose product has homology to protein kinases. Gene 117, 137-140.[Medline]

Boleti, H., Karsenti, E. and Vernos, I (1996). Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis. Cell 84, 49-59.[Medline]

Brinkley, B. R (1985). Microtubule organizing centers. Annu. Rev. Cell Biol 1, 145-172.

Centonze, V. E. and Borisy, G. G (1990). Nucleation of microtubules from mitotic centrosomes is modulated by a phosphorylated epitope. J. Cell Sci 95, 405-411.[Abstract/Free Full Text]

Compton, D. A (1998). Focusing on spindle poles. J. Cell Sci 111, 1477-1481.[Abstract]

Descombes, P. and Nigg, E. A (1998). The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J 17, 1328-1335.[Medline]

Evans, L., Mitchison, T. and Kirschner, M (1985). Influence of the centrosome on the structure of nucleated microtubules. J. Cell Biol 100, 1185-1191.[Abstract/Free Full Text]

Fava, F., Raynaud-Messina, B., Leung-Tack, J., Mazzolini, L., Li, M., Guillemot, J. C., Cachot, D., Tollon, Y., Ferrara, P. and Wright, M (1999). Human 76p: a new member of the-tubulin-associated protein family. J. Cell Biol 147, 857-868.[Abstract/Free Full Text]

Felix, M.-A., Antony, C., Wright, M. and Maro, B (1994). Centrosome assembly in vitro: role of gamma-tubulin recruitment in Xenopus sperm aster formation. J. Cell Biol 124, 19-31.[Abstract/Free Full Text]

Fry, A. M., Schultz, S. J., Bartek, J. and Nigg, E. A (1995). Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans. J. Biol. Chem 2705, 12899-12905.

Fry, A. M. and Nigg, E. A (1997). Characterization of mammalian NIMA-related kinases. Meth. Enzymol 283, 270-282.[Medline]

Fry, A. M., Meraldi, P. and Nigg, E. A (1998). A centrosomal function for the human Nek2 protein kinase, a member of the NIMA-family of cell cycle regulators. EMBO J 17, 470-481.[Medline]

Fry, A. M., Mayor, T., Meraldi, P., Stierhof, Y.-D., Tanaka, K. and Nigg, E. A (1998). C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. J. Cell Biol 141, 1563-1574.[Abstract/Free Full Text]

Fry, A. M., Arnaud, L. and Nigg, E. A (1999). Activity of the human centrosomal kinase, Nek2, depends upon an unusual leucine zipper dimerization motif. J. Biol. Chem 274, 16304-16310.[Abstract/Free Full Text]

Glotzer, M., Murray, A. W. and Kirschner, M. W (1991). Cyclin is degraded by the ubiquitin pathway. Nature 349, 132-138.[Medline]

Jones, D. G. and Rosamond, J (1990). Isolation of a novel protein kinase-encoding gene from yeast by oligodeoxyribonucleotide probing. Gene 90, 87-92.[Medline]

Kellogg, D. R., Moritz, M. and Alberts, B. M (1994). The centrosome and cellular organization. Annu. Rev. Biochem 63, 639-674.[Medline]

Krien, M. J. E., Bugg, S. J., Palatsides, M., Asouline, G., Morimyo, M. and O'Connell, M. J (1998). A NIMA homologue promotes chromatin condensation in fission yeast. J. Cell Sci 111, 967-976.[Abstract]

Lu, K. P. and Means, A. R (1994). Expression of the non-catalytic domain of the NIMA kinase causes a G2arrest in Aspergillus nidulans. EMBO J 13, 2103-2113.[Medline]

Lu, K. P. and Hunter, T (1995). Evidence for a NIMA-like mitotic pathway in vertebrate cells. Cell 81, 413-424.[Medline]

Martin, O. C., Gunawardane, R. N., Iwamatsu, A. and Zheng, Y (1998). Xgrip109: atubulin-associated protein with an essential role in tubulin ring complex (TuRC) assembly and centrosome function. J. Cell Biol 141, 675-687.[Abstract/Free Full Text]

Merdes, A., Ramyar, K., Vechio, J. D. and Cleveland, D. W (1996). A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell 87, 447-458.[Medline]

Merdes, A. and Cleveland, D. W (1997). Pathways of spindle pole formation: different mechanisms; conserved components. J. Cell Biol 138, 953-956.[Free Full Text]

Merdes, A. and Cleveland, D. W (1998). The role of NuMA in the interphase nucleus. J. Cell Sci 111, 71-79.[Abstract]

Murray, A. W (1991). Cell cycle extracts. Meth. Cell Biol 36, 581-605.[Medline]

Navara, C. S., Hewitson, L. C., Simerly, C. R., Sutovsky, P. and Schatten, G (1997). The implications of a paternally derived centrosome during human fertilization: consequences for reproduction and the treatment of male factor infertility. Am. J. Reprod. Immunol 37, 39-49.

O'Connell, M. J., Norbury, C. and Nurse, P (1994). Premature chromatin condensation upon accumulation of NIMA. EMBO J 13, 4926-4937.[Medline]

Oakley, B. R. and Morris, N. R (1983). A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase. J. Cell Biol 96, 1155-1158.[Abstract/Free Full Text]

Osmani, S. A., Pu, R. T. and Morris, N. R (1988). Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase. Cell 53, 237-244.[Medline]

Osmani, A. H., McGuire, S. L. and Osmani, S. A (1991). Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. Cell 67, 283-291.[Medline]

Osmani, A. H., O'Donnell, K., Pu, R. T. and Osmani, S. A (1991). Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint. EMBO J 10, 2669-2679.[Medline]

Pu, R. T., Xu, G., Wu, L., Vierula, J., O'Donnell, K., Ye, X. S. and Osmani, S. A (1995). Isolation of a functional homolog of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans and functional analysis of conserved residues. J. Biol. Chem 270, 18110-18116.[Abstract/Free Full Text]

Rhee, K. and Wolgemuth, D. J (1997). The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes. Development 124, 2167-2177.[Abstract]

Sawin, K. E. and Mitchison, T. J (1991). Mitotic spindle assembly by two different pathways in vitro. J. Cell Biol 112, 925-940.[Abstract/Free Full Text]

Schatten, G (1994). The centrosome and its mode of inheritance: the reduction of the centrosome during gametogenesis and its restoration during fertilization. Dev. Biol 165, 299-335.[Medline]

Schnackenberg, B. J., Khodjakov, A., Reider, C. L. and Palazzo, R. E (1998). The disassembly and reassembly of functional centrosomes in vitro. Proc. Nat. Acad. Sci. USA 95, 9295-9300.[Abstract/Free Full Text]

Schultz, S. J., Fry, A. M., Sutterlin, C., Ried, T. and Nigg, E. A (1994). Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell Growth Differ 5, 625-635.[Abstract]

Schweitzer, B. and Philippsen, P (1992). NPK1, a nonessential protein kinase gene in Saccharomyces cerevisiae with similarity to Aspergillus nidulans nimA. Mol. Gen. Genet 234, 164-167.[Medline]

Simerly, C., Zoran, S. S., Payne, C., Dominko, T., Sutovsky, P., Navarra,C. S., Salisbury, J. L. and Schatten, G (1999). Biparental inheritance of-tubulin during human fertilization: molecular reconstitution of functional zygotic centrosomes in inseminated human oocytes and in cell-free extracts nucleated by human sperm. Mol. Biol. Cell 10, 2955-2969.[Abstract/Free Full Text]

Smith, J. C. and Tata, J. R (1991). Xenopus cell lines. Meth. Cell Biol 36, 635-654.[Medline]

Stearns, T., Evans, L. and Kirschner, M (1991). -Tubulin is a highly conserved component of the centrosome. Cell 65, 825-836.[Medline]

Stearns, T. and Kirschner, M (1994). In vitro reconstitution of centrosome assembly and function: the central role of-tubulin. Cell 76, 623-637.[Medline]

Tanaka, K., Parvinen, M. and Nigg, E. A (1997). The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis. Exp. Cell Res 237, 264-274.[Medline]

Tassin, A.-M., Celati, C., Moudjou, M. and Bornens, M (1998). Characterization of the human homologue of the yeast Spc98p and its association with-tubulin. J. Cell Biol 141, 689-701.[Abstract/Free Full Text]

Uto, K., Nakajo, N. and Sagata, N (1999). Two structural variants of Nek2 kinase, termed Nek2A and Nek2B, are differentially expressed in Xenopus tissues and development. Dev. Biol 208, 456-464.[Medline]

Vandre, D. D., Davis, F. M., Rao, P. N. and Borisy, G. G (1984). Phosphoproteins are components of mitotic microtubule organising centers. Proc. Nat. Acad. Sci. USA 81, 4439-4443.[Abstract/Free Full Text]

Vandre, D. D., Davis, F. M., Rao, P. N. and Borisy, G. G (1986). Distribution of cytoskeletal proteins sharing a conserved phosphorylated epitope. Eur. J. Cell Biol 41, 72-81.[Medline]

Wu, L., Osmani, S. A. and Mirabito, P. M (1998). A role for NIMA in the nuclear localization of cyclin B in Aspergillus nidulans. J. Cell Biol 141, 1575-1587.[Abstract/Free Full Text]

Ye, X. S., Fincher, R. R., Tang, A., O'Donnell, K. and Osmani, S. A (1996). Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis. EMBO J 15, 3599-3610.[Medline]

Ye, X. S., Fincher, R. R., Tang, A., Osmani, A. H. and Osmani, S. A (1998). Regulation of the anaphase-promoting complex/cyclosome by bimAAPC3and proteolysis of NIMA. Mol. Biol. Cell 9, 3019-3030.[Abstract/Free Full Text]

Zheng, Y., Wong, M. L., Alberts, B. and Mitchison, T (1995). Nucleation of microtubule assembly by a-tubulin-containing ring complex. Nature 378, 578-583.[Medline]

Zimmerman, W., Sparks, C. A. and Doxsey, S. J (1999). Amorphous no longer: the centrosome comes into focus. Curr. Opin. Cell Biol 11, 122-128.[Medline]




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