Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription

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[Abstract] [Full Text] [PDF]

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J. Biol. Chem., October 1, 2004; 279(40): 41998 - 42007.
[Abstract] [Full Text] [PDF]

D. W. Young, S. K. Zaidi, P. S. Furcinitti, A. Javed, A. J. van Wijnen, J. L. Stein, J. B. Lian, and G. S. Stein
Quantitative signature for architectural organization of regulatory factors using intranuclear informatics
J. Cell Sci., October 1, 2004; 117(21): 4889 - 4896.
[Abstract] [Full Text] [PDF]

G. L. Barnes, K. E. Hebert, M. Kamal, A. Javed, T. A. Einhorn, J. B. Lian, G. S. Stein, and L. C. Gerstenfeld
Fidelity of Runx2 Activity in Breast Cancer Cells Is Required for the Generation of Metastases-Associated Osteolytic Disease
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[Abstract] [Full Text] [PDF]

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Homeobox Protein Msx2 Acts as a Molecular Defense Mechanism for Preventing Ossification in Ligament Fibroblasts
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[Abstract] [Full Text] [PDF]

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VWRPY motif-dependent and -independent roles of AML1/Runx1 transcription factor in murine hematopoietic development
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[Abstract] [Full Text] [PDF]

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Molecular cloning and characterization of Mustang, a novel nuclear protein expressed during skeletal development and regeneration
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[Abstract] [Full Text] [PDF]

S. K. Zaidi, D. W. Young, S. M. Pockwinse, A. Javed, J. B. Lian, J. L. Stein, A. J. van Wijnen, and G. S. Stein
Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells
PNAS, December 9, 2003; 100(25): 14852 - 14857.
[Abstract] [Full Text] [PDF]

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Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4-/CD8+ Thymocytes
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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

M. Lepourcelet and R. A. Shivdasani
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[Abstract] [Full Text] [PDF]

J. J. Westendorf, S. K. Zaidi, J. E. Cascino, R. Kahler, A. J. van Wijnen, J. B. Lian, M. Yoshida, G. S. Stein, and X. Li
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[Abstract] [Full Text] [PDF]

K. S. Harrington, A. Javed, H. Drissi, S. McNeil, J. B. Lian, J. L. Stein, A. J. van Wijnen, Y.-L. Wang, and G. S. Stein
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J. Cell Sci., November 1, 2002; 115(21): 4167 - 4176.
[Abstract] [Full Text] [PDF]

S. K. Zaidi, A. J. Sullivan, A. J. van Wijnen, J. L. Stein, G. S. Stein, and J. B. Lian
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[Abstract] [Full Text] [PDF]

H. N. Nuthall, J. Husain, K. W. McLarren, and S. Stifani
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[Abstract] [Full Text] [PDF]

R. C. D'Alonzo, N. Selvamurugan, G. Karsenty, and N. C. Partridge
Physical Interaction of the Activator Protein-1 Factors c-Fos and c-Jun with Cbfa1 for Collagenase-3 Promoter Activation
J. Biol. Chem., January 4, 2002; 277(1): 816 - 822.
[Abstract] [Full Text]

W. Liu, S. Toyosawa, T. Furuichi, N. Kanatani, C. Yoshida, Y. Liu, M. Himeno, S. Narai, A. Yamaguchi, and T. Komori
Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures
J. Cell Biol., October 1, 2001; 155(1): 157 - 166.
[Abstract] [Full Text] [PDF]

C. Banerjee, A. Javed, J.-Y. Choi, J. Green, V. Rosen, A. J. van Wijnen, J. L. Stein, J. B. Lian, and G. S. Stein
Differential Regulation of the Two Principal Runx2/Cbfa1 N-Terminal Isoforms in Response to Bone Morphogenetic Protein-2 during Development of the Osteoblast Phenotype
Endocrinology, September 1, 2001; 142(9): 4026 - 4039.
[Abstract] [Full Text] [PDF]

J.-Y. Choi, J. Pratap, A. Javed, S. K. Zaidi, L. Xing, E. Balint, S. Dalamangas, B. Boyce, A. J. van Wijnen, J. B. Lian, et al.
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development
PNAS, June 28, 2001; (2001) 151236498.
[Abstract] [Full Text] [PDF]

A. Javed, G. L. Barnes, B. O. Jasanya, J. L. Stein, L. Gerstenfeld, J. B. Lian, and G. S. Stein
runt Homology Domain Transcription Factors (Runx, Cbfa, and AML) Mediate Repression of the Bone Sialoprotein Promoter: Evidence for Promoter Context-Dependent Activity of Cbfa Proteins
Mol. Cell. Biol., April 15, 2001; 21(8): 2891 - 2905.
[Abstract] [Full Text]

S. K. Zaidi, A. Javed, J.-Y. Choi, A. J. van Wijnen, J. L. Stein, J. B. Lian, and G. S. Stein
A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene
J. Cell Sci., January 9, 2001; 114(17): 3093 - 3102.
[Abstract] [Full Text] [PDF]

K. W. McLarren, F. M. Theriault, and S. Stifani
Association with the Nuclear Matrix and Interaction with Groucho and RUNX Proteins Regulate the Transcription Repression Activity of the Basic Helix Loop Helix Factor Hes1
J. Biol. Chem., January 5, 2001; 276(2): 1578 - 1584.
[Abstract] [Full Text] [PDF]

J. Hess, D. Porte, C. Munz, and P. Angel
AP-1 and Cbfa/Runt Physically Interact and Regulate Parathyroid Hormone-dependent MMP13 Expression in Osteoblasts through a New Osteoblast-specific Element 2/AP-1 Composite Element
J. Biol. Chem., June 1, 2001; 276(23): 20029 - 20038.
[Abstract] [Full Text] [PDF]

S. Gutierrez, A. Javed, D. K. Tennant, M. van Rees, M. Montecino, G. S. Stein, J. L. Stein, and J. B. Lian
CCAAT/Enhancer-binding Proteins (C/EBP) beta and delta Activate Osteocalcin Gene Transcription and Synergize with Runx2 at the C/EBP Element to Regulate Bone-specific Expression
J. Biol. Chem., January 4, 2002; 277(2): 1316 - 1323.
[Abstract] [Full Text] [PDF]

J.-Y. Choi, J. Pratap, A. Javed, S. K. Zaidi, L. Xing, E. Balint, S. Dalamangas, B. Boyce, A. J. van Wijnen, J. B. Lian, et al.
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development
PNAS, July 17, 2001; 98(15): 8650 - 8655.
[Abstract] [Full Text] [PDF]

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