Contraction of collagen matrices mediated by alpha2beta1A and alpha(v)beta3 integrins

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Bell, E., Ivarsson, B. and Merrill, C (1979). Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc. Nat. Acad. Sci. USA 76, 1274-1278.[Abstract/Free Full Text]

Brown, R. A., Talas, G., Porter, R. A., McGrouther, D. A. and Eastwood, M (1996). Balanced mechanical forces and microtubule contribution to fibroblast contraction. J. Cell. Physiol 169, 439-447.[Medline]

Carver, W., Molano, I., Reaves, T. A., Borg, T. K. and Terracio,L (1995). Role of the1 1integrin complex in collagen gel contraction in vitro by fibroblasts. J. Cell. Physiol 165, 425-437.[Medline]

Chen, Y., O'Toole, T. E., Leong, L., Liu, B., Diaz-Gonzalez, F. and Ginsberg, M. H (1995). Beta 3 integrin-mediated fibrin clot retraction by nucleated cells: differing behavior ofIIb 3andv 3. Blood 86, 2606-2615.[Abstract/Free Full Text]

Chiquet-Ehrismann, R., Tannheimer, M., Koch, M., Brunner, A., Spring, J., Martin, D., Baumgartner, S. and Chiquet, M (1994). Tenascin-C expression by fibroblasts is elevated in stressed collagen gels. J. Cell Biol 127, 2093-2101.[Abstract/Free Full Text]

Clark, R. A., Folkvord, J. M., Hart, C. E., Murray, M. J. and McPherson, J. M (1989). Platelet isoforms of platelet-derived growth factor stimulate fibroblasts to contract collagen matrices. J. Clin. Invest 84, 1036-1040.

Clark, R. A (1993). Regulation of fibroplasia in cutaneous wound repair. Am. J. Med. Sci 306, 42-48.[Medline]

Clark, R. A., Nielsen, L. D., Welch, M. P. and McPherson, J. M (1995). Collagen matrices attenuate the collagen-synthetic response of cultured fibroblasts to TGF-beta. J. Cell Sci 108, 1251-1261.[Abstract]

Davies, P. F (1995). Flow-mediated endothelial mechanotransduction. Physiol. Rev 75, 519-560.[Abstract/Free Full Text]

Davis, G. E (1992). Affinity of integrins for damaged extracellular matrix:v 3 binds to denatured collagen type Ic through RGD sites. Biochem. Biophys. Res. Commun 182, 1025-1031.[Medline]

Eckes, B., C. Msauch, G. Huppe and T. Krieg (1993). Downregulation of collagen synthesis in fibroblasts within three-dimensional collagen lattices involves transcription mechanisms. FEBS Lett 318, 129-133.[Medline]

Edelman, J., M. Chan, B. M. C. Uniyal, S. Onodera, H. Wang, D. Z. Damjanovich, L. Latzer, D. B. Finberg and J. M. Bergelson (1994). The mouse VLA-2 homologue supports collagen and laminin adhesion but not virus binding. Cell Adhes. Commun 2, 131-143.[Medline]

Ehrlich, H. P. and D. J. Wyler (1983). Fibroblast contraction of collagen lattices in vitro : Inhibition by chronic inflammatory cell mediators. J. Cell. Physiol 116, 345-351.[Medline]

Eicholtz, T., K. Jalink, I. Fahrenfort and Moolenaar, W. H (1993). The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem. J 291, 677-680.

Elsdale, T. and Bard, J (1972). Collagen substrata for studies on cell behavior. J. Cell Biol 54, 626-637.[Abstract/Free Full Text]

F\212ssler, R., Pfaff, M., Murphy, J., Noegel, A. A., Johansson, S., Timpl, R. and Albrecht, R (1995). Lack of1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts. J. Cell Biol 128, 979-988.[Abstract/Free Full Text]

Greiling, D. and Clark, R. A (1997). Fibronectin provides a conduit for fibroblast transmigration from collagenous stroma into fibrin clot provisional matrix. J. Cell Sci 110, 861-870.[Abstract]

Grinnell, F (1994). Fibroblasts, myofibroblasts, and wound contraction. J. Cell Biol 124, 401-404.[Free Full Text]

Grinnell, F., Ho, C. H., Lin, Y. C. and Skuta, G (1999). Differences in the regulation of fibroblast contraction of floating versus stress collagen matrices. J. Biol. Chem 274, 918-923.[Abstract/Free Full Text]

Guidry, C. and Grinnell, F (1985). Studies on the mechanism of hydrated collagen gel reorganization by human skin fibroblasts. J. Cell Sci 79, 67-81.[Abstract]

Gullberg, D., Tingsrom, A., Thuresson, A., Olsson, L., Terracio, L., Borg, T. K. and Rubin, K (1990). Beta 1 integrin-mediated collagen gel contraction is stimulated by PDGF. Exp. Cell. Res 186, 264-272.[Medline]

Halliday, N. L. and Tomasek, J. J (1995). Mechanical properties of the extracellular matrix influence fibronectin fibril assembly invitro. Exp. Cell Res 217, 109-117.[Medline]

Ingber, D (1991). Integrins as mechanochemical transducers. Curr. Opin. Cell Biol 3, 841-848.[Medline]

Katagiri, Y., Hiroyama, T., Akamatsu, N., Suzuki, H., Yamazaki, H. and Tanoue,K (1995). Involvement ofv 3integrin in mediating fibrin gel retraction. J. Biol. Chem 270, 1785-1790.[Abstract/Free Full Text]

Kitamura, M., Maruyama, N., Mitarai, T., Nagasawa, R., Yoshida, H. and Sakai, O (1992). Extracellular matrix contraction by cultured mesangial cells: modulation by transforming growth factor-and matrix components. Exp. Mol. Path 56, 132-143.[Medline]

Klein, C. E., Dressel, D., Steinmayer, T., Mauch, C., Eckes, B., Krieg, T., Bankert, R. B. and Weber, L (1991). Integrin2 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils. J. Cell Biol 115, 1427-1436.[Abstract/Free Full Text]

Kolodney, M. S. and Wysolmerski, R. B (1992). Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study. J. Cell Biol 11, 73-82.

Koyoma, H., Raines, E. W., Bornfeldt, K. E., Roberts, J. M. and Ross, R (1996). Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of cdk2 inhibition. Cell 87, 1069-1078.[Medline]

Lambert, C. A., Soudant, E. P., Nusgens, B. V. and Lapiere, C. M (1998). Pretranslational regulation of extracellular matrix macromolecules and collagenase expression in fibroblasts by mechanical forces. Lab. Invest 66, 444-451.[Medline]

Langholz, O., Rockel, D., Mauch, C., Kozlowska, E., Bank, I., Krieg, T. and Eckes, B (1995). Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by1 1and2 1integrins. J. Cell Biol 131, 1903-1915.[Abstract/Free Full Text]

Lee, M.-J., Van Brocklyn, J. R., Thangada, S., Liu, C. H., Hand, A. R., Menzeleev, R., Spiegel, S. and Hla, T (1998). Sphingosine-1-phosphate as a ligand for the G-protein-coupled receptor EDG-1. Science 279, 1552-1555.[Abstract/Free Full Text]

Lee, Y. R., Oshita, Y., Tsuboi, R. and Ogawa, H (1996). Combination of insulin-like growth factor (IGF)-1 and IGF-binding protein-1 promotes fibroblast-embedded collagen gel contraction. Endocrinology 137, 5278-5283.[Abstract]

Maniotis, A. J., Chen, C. S. and Ingber,D. E (1997). Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc. Nat. Acad. Sci. USA 94, 849-854.[Abstract/Free Full Text]

Mochitate, K., Pawelek, P. and Grinnell, F (1991). Stress relaxation of contracted collagen gels: disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis. Exp. Cell Res 193, 198-207.[Medline]

Moulin, V., Castilloux, G., Auger, F. A., Garrel, D., O'Conner-McCourt, M. D. and Germain, L (1998). Modulated response to cytokines of human wound healing myofibroblasts compared to dermal fibroblasts. Exp. Cell Res 238, 283-293.[Medline]

Moroi, M. and Jung, S. M (1997). Platelet receptors for collagen. Thromb. & Haemostas 78, 439-444.[Medline]

Nakagawa, S., Pawelek, P. and Grinnell, F (1989). Long-term culture of fibroblasts in contracted collagen gels: effects on cell growth and biosynthetic activity. J. Invest. Dermatol 93, 792-798.[Medline]

Pierschbacher, M. D. and Ruoslahti, E (1984). The cell attachment activity of fibronectin can be duplicated by small fragments of the molecule. Nature 309, 30-33.[Medline]

Pilcher, B. K., Levine, N. S. and Tomasek, J. J (1995). Thrombin promotion of isometric contraction in fibroblasts: its extracellular mechanism of action. Plast. Reconstr. Surg 96, 1188-1195.[Medline]

Rayan, G. M., Parizi, M. and Tomasek, J. J (1995). Pharmacologic regulation of Dupuytren's fibroblast contraction in vitro. J. Hand Surg 21, 1065-1070.

Riikonen, T., Koivisot, L., Viihinen, P. and Heino, J (1995). Transforming growth factor-regulates collagen gel contraction by increasing 21integrin expression in osteogenic cells. J. Biol. Chem 270, 376-382.[Abstract/Free Full Text]

Rosenfeldt, H., Lee, D. J. and Grinnell,F (1998). Increased c-fos mRNA expression by human fibroblasts contracting stressed collagen matrices. Mol. Cell. Biol 18, 2659-2667.[Abstract/Free Full Text]

Sakai, T., Peyruchaud, O., F\212ssler, R. and Mosher, D. F (1998). Restoration of1A integrins is required for lysophosphatidic acid-induced migration of 1-null mouse fibroblastic cells. J. Biol. Chem 273, 19378-19382.[Abstract/Free Full Text]

Schneller, M., Vuori, K. and Ruoslahti, E (1997). v 3integrin associates with activated insulin and PDGPreceptors and potentiates the biological activity of PDGF. EMBO J 18, 5600-5607.

Shiro, J. A., Chan, B. M. C., Roswit, W. T., Kassner, P. D., Pentland, A. P., Hemler, M. D., Eisen, A. Z. and Kupper,T. S (1991). Integrins2 1(VLA-2) mediates reorganization and contraction of collagen matrices by human cells. Cell 67, 403-410.[Medline]

Shyy, J. and Chien, S (1997). Role of integrins in cellular responses to mechanical stress and adhesion. Curr. Opin. Cell Biol 9, 707-713.[Medline]

Stopak, D. and Harris, A. K (1982). Connective tissue morphogenesis by fibroblast traction. Dev. Biol 90, 383-398.[Medline]

Thoreson, W. B., Khandalavala, B. N., Manahan, R. G., Polyak, I. A., Liu, J. L. and Chacko, D. M (1997). Lysophosphatidic acid stimulates proliferation of human retinal pigment epithelial cells. Curr. Eye Res 16, 698-702.[Medline]

Tomasek, J. J., Hay, E. D. and Fujiwara, K (1982). Collagen modulates cell shape and cytoskeleton of embryonic corneal and fibroma fibroblasts: distribution of actin,-actin, and myosin. Dev. Biol 92, 107-122.[Medline]

Tomasek, J. J., Haaksma, C. J., Eddy, R. J. and Vaughan,M. B (1992). Fibroblast contraction occurs on release of tension in attached collagen lattices: Dependency on an organized actin cytoskeleton and serum. Anat. Record 232, 359-368.[Medline]

Vernon, R. B. and Sage, E. H (1996). Contraction of fibrillar type 1 collagen by endothelial cells: A study in vitro. J. Cell. Biochem 60, 185-197.[Medline]

Wakita, H., Matsushita, K., Nishimura, K., Tokura, Y., Furukawa, F. andTakigawa, M (1998). Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes. J. Invest. Dermatol 110, 253-258.[Medline]

Wennerberg, K., Lohikangas, L., Gullberg, D., Pfaff, M., Johansson, S. and F\212ssler,R (1996). 1 Integrin-dependent and-independent polymerization of fibronectin. J. Cell Biol 132, 227-238.[Abstract/Free Full Text]

Wennstrom, S., Siegbahn, A., Yokote, K., Arvidsson, A. K., Heldin, C. H., Moris, S. and Claesson-Welsh, L (1994). Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3kinase. Oncogene 9, 651-660.[Medline]

Werb, Z., Tremble, P. and Damsky, C (1990). Regulation of extracellular matrix degradation by extracellular matrix interactions. Cell Diff. Dev 32, 299-306.[Medline]

Xu, J. and Clark, R. A. F (1996). Extracellular matrix alters PDGF regulation of fibroblast integrins. J. Cell Biol 132, 239-249.[Abstract/Free Full Text]

Xu, J., Zutter, M. M., Santoro, S. A. and Clark, R. A (1998). A three-dimensional collagen lattice activates NF-B in human fibroblasts: role in integrin 2 gene expression and tissue remodeling. J. Cell Biol 140, 709-719.[Abstract/Free Full Text]

Yatomi, Y., Yamamura, S., Ruan, F. and Igarashi, Y (1997). Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. J. Biol. Chem 272, 5291-5297.[Abstract/Free Full Text]

Zhang, Q., Peyruchaud, O., French, K. J., Magnusson, M. K. and Mosher, D. F (1999). Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a rho-dependent signal pathway. Blood 93, 2984-2990.[Abstract/Free Full Text]

Zondag, G. C. M., Postma, F. R., Van Etten, I., Verlaan, I. and Moolenaar, W. H (1998). Sphingosine-1-phosphate signaling through the G-protein-coupled receptor Edg-1. Biochem. J 333, 605-609.

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				O. S. Svendsen, A. Liden, T. Nedrebo, K. Rubin, and R. K. Reed Integrin {alpha}v{beta}3 acts downstream of insulin in normalization of interstitial fluid pressure in sepsis and in cell-mediated collagen gel contraction Am J Physiol Heart Circ Physiol, August 1, 2008; 295(2): H555 - H560. [Abstract] [Full Text] [PDF]

				H. Xia, D. Diebold, R. Nho, D. Perlman, J. Kleidon, J. Kahm, S. Avdulov, M. Peterson, J. Nerva, P. Bitterman, et al. Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis J. Exp. Med., July 7, 2008; 205(7): 1659 - 1672. [Abstract] [Full Text] [PDF]

				H. Jiang, S. Rhee, C.-H. Ho, and F. Grinnell Distinguishing fibroblast promigratory and procontractile growth factor environments in 3-D collagen matrices FASEB J, July 1, 2008; 22(7): 2151 - 2160. [Abstract] [Full Text] [PDF]

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				R. S. Nho, H. Xia, D. Diebold, J. Kahm, J. Kleidon, E. White, and C. A. Henke PTEN Regulates Fibroblast Elimination during Collagen Matrix Contraction J. Biol. Chem., November 3, 2006; 281(44): 33291 - 33301. [Abstract] [Full Text] [PDF]

				C. Franco, B. Ho, D. Mulholland, G. Hou, M. Islam, K. Donaldson, and M. P. Bendeck Doxycycline Alters Vascular Smooth Muscle Cell Adhesion, Migration, and Reorganization of Fibrillar Collagen Matrices Am. J. Pathol., May 1, 2006; 168(5): 1697 - 1709. [Abstract] [Full Text] [PDF]

				A. Liden, A. Berg, T. Nedrebo, R. K. Reed, and K. Rubin Platelet-Derived Growth Factor BB-Mediated Normalization of Dermal Interstitial Fluid Pressure After Mast Cell Degranulation Depends on {beta}3 but Not {beta}1 Integrins Circ. Res., March 17, 2006; 98(5): 635 - 641. [Abstract] [Full Text] [PDF]

				D. G. McNeel, J. Eickhoff, F. T. Lee, D. M. King, D. Alberti, J. P. Thomas, A. Friedl, J. Kolesar, R. Marnocha, J. Volkman, et al. Phase I Trial of a Monoclonal Antibody Specific for {alpha}v{beta}3 Integrin (MEDI-522) in Patients with Advanced Malignancies, Including an Assessment of Effect on Tumor Perfusion Clin. Cancer Res., November 1, 2005; 11(21): 7851 - 7860. [Abstract] [Full Text] [PDF]

				H. Jiang and F. Grinnell Cell-Matrix Entanglement and Mechanical Anchorage of Fibroblasts in Three-dimensional Collagen Matrices Mol. Biol. Cell, November 1, 2005; 16(11): 5070 - 5076. [Abstract] [Full Text] [PDF]

				A. L. Feire, H. Koss, and T. Compton Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain PNAS, October 26, 2004; 101(43): 15470 - 15475. [Abstract] [Full Text] [PDF]

				J. Jokinen, E. Dadu, P. Nykvist, J. Kapyla, D. J. White, J. Ivaska, P. Vehvilainen, H. Reunanen, H. Larjava, L. Hakkinen, et al. Integrin-mediated Cell Adhesion to Type I Collagen Fibrils J. Biol. Chem., July 23, 2004; 279(30): 31956 - 31963. [Abstract] [Full Text] [PDF]

				N. Ferri, K. J. Garton, and E. W. Raines An NF-{kappa}B-dependent Transcriptional Program Is Required for Collagen Remodeling by Human Smooth Muscle Cells J. Biol. Chem., May 23, 2003; 278(22): 19757 - 19764. [Abstract] [Full Text] [PDF]

				E. Tamariz and F. Grinnell Modulation of Fibroblast Morphology and Adhesion during Collagen Matrix Remodeling Mol. Biol. Cell, November 1, 2002; 13(11): 3915 - 3929. [Abstract] [Full Text] [PDF]