Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status

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Andrews, N. C. and Faller, D. V (1991). A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucl. Acids Res 19, 2499-2504.[Free Full Text]

Bittinger, F., Gonz\207lez-Garc\222a, J. L., Klein, C. L., Brochhausen, C., Offner, F. and Kirkpatrick, C. J (1998). Production of superoxide by human malignant melanoma cells. Melanoma Res 8, 381-387.[Medline]

Blair, S. L., Heerdt, P., Sachar, S., Abolhoda, A., Hochwald, S., Cheng, H. and Burt, M (1997). Glutathione metabolism in patients with non-small cell lung cancers. Cancer Res 57, 152-155.[Abstract/Free Full Text]

Burdon, R. H (1995). Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Rad. Biol. Med 18, 775-794.[Medline]

Clark, S. and Konstantopoulos, N (1993). Sulfhydryl agents modulate insulin-and epidermal growth factor (EGF)-receptor kinase via reaction with intracellular receptor domains: differential effects on basal versus activated receptors. Biochem. J 292, 217-223.

Clement, M.-V. and Stamenkovic, I (1996). Superoxide anion is a natural inhibitor of Fas-mediated cell death. EMBO J 15, 216-225.[Medline]

Cotgreave, I. A. and Gerdes, R. G (1998). Recent trends in glutathione biochemistry \320 Glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation?. Biochem. Biophys. Res. Commun 242, 1-9.[Medline]

Del Bello, B., Paolicchi, A., Comporti, M., Pompella, A. and Maellaro, E (1999). Hydrogen peroxide produced during gamma-glutamyl transpeptidase activity is involved in prevention of apoptosis and maintenance of cell proliferation in U937 cells. FASEB J 13, 69-79.[Abstract/Free Full Text]

Dominici, S., Valentini, M., Maellaro, E., Del Bello, B., Paolicchi, A., Lorenzini, E., Tongiani, R., Comporti, M. and Pompella, A (1999). Redox modulation of cell surface protein thiols in U937 lymphoma cells: the role of gamma-glutamyl transpeptidase-dependent H2O2production and S-thiolation. Free Rad. Biol. Med 27, 623-635.[Medline]

Drozdz, R., Parmentier, C., Hachad, H., Leroy, P., Siest, G. and Wellman, M (1998). gamma-Glutamyltransferase dependent generation of reactive oxygen species from aglutathione/transferrin system. Free Rad. Biol. Med 25, 786-92.[Medline]

Flohe, L., Brigelius-Flohe, R., Saliou, C., Traber, M. G. and Packer, L (1997). Redox regulation of NF-kappa B activation. Free Rad. Biol. Med 22, 1115-1126.[Medline]

Gallagher, D. L., Betteridge, L. J., Patel, M. K. and Schachter, M (1993). Effect of oxidants on vascular smooth muscle proliferation. Biochem. Soc. Trans 21, 98-.

Genaro, A. M., Hortelano, S., Alvarez, A., Mart\223nez-A., C. and Bosc\210, L (1995). Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J. Clin. Invest 95, 1884-1890.

Griffith, O. W. and Meister A (1979). Translocation of intracellular glutathione to membrane bound gamma-glutamyl transpeptidase as a discrete step in the gamma-glutamyl cycle: glutathionuria after inhibition of the transpeptidase. Proc. Nat. Acad. Sci. USA 76, 268-279.[Abstract/Free Full Text]

Griffith, O. W. and Tate, S. S (1980). The apparent glutathione-oxidase activity of-glutamyl transpeptidase. J. Biol. Chem 255, 5011-5014.[Abstract/Free Full Text]

Hanigan, M. H. and Frierson, H. F. Jr (1996). Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue. J. Histochem. Cytochem 44, 1101-1108.[Abstract]

Herbert, J. M., Bono, F. and Savi, P (1996). The mitogenic effect of H2O2for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor. FEBS Lett 395, 43-47.[Medline]

Higgins, K. A., Perez, J. R., Coleman, T. A., Dorshkind, K., McComas, W. A., Sarmiento, U. M., Rosen, C. A. and Narayanan, R (1993). Antisense inhibition of the p65 subunit of NF-B blocks tumorigenicity and causes tumor regeression. Proc. Nat. Acad. Sci. USA 90, 9901-9905.[Abstract/Free Full Text]

Hochwald, S. N., Harrison, L. E., Rose, D. M., Anderson, M. and Burt, M. E (1997). Elevation of glutathione and related enzyme activities in high-grade and metastatic extremity soft tissue sarcoma. Ann. Surg. Oncol 4, 303-309.[Abstract]

Huang, R. P., Wu, J. X., Fan, Y. and Adamson, E. D (1996). UV activates growth factor receptors via reactive oxygen intermediates. J. Cell Biol 133, 211-220.[Abstract/Free Full Text]

Huseby, N. E. and Str\232mme, J. H (1974). Practical points regarding routine determination of gamma-glutamyl transferase (-GT) in serum with a kinetic method at 37degC. Scand.J. Clin. Lab. Invest 34, 357-361.[Medline]

Lander, H. M (1997). An essential role for free radicals and derived species in signal transduction. FASEB J 11, 118-124.[Abstract]

Lash, L. H. and Jones, D. P (1986). Purification and properties of the membranal thiol oxidase from porcine kidney. Arch. Biochem. Biophys 247, 120-130.[Medline]

Maellaro, E., Del Bello, B. and Comporti, M (1996). Protection by ascorbate against apoptosis of thymocytes: implications of ascorbate-induced nonlethal oxidative stress and poly(ADP-ribosyl)ation. Exp. Cell Res 226, 105-113.[Medline]

Melezinek, I., Borovansky, J., Elleder, M. and Bubnova, E (1998). Tumour tissue is a source of gamma-glutamyl transpeptidase sialoform in the sera of melanoma-bearing mice. Melanoma Res 8, 39-45.[Medline]

Mohanty, J. G., Jaffe, J. S., Shulman, E. S. and Raible, D. G (1997). A highly sensitive fluorescent micro-assay of H2O2release from activated human leukocytes using a dihydroxyphenoxazine derivative. J. Immunol. Meth 202, 133-141.[Medline]

Monteiro, H. P. and Stern, A (1996). Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways. Free Rad. Biol. Med 21, 323-333.[Medline]

Murata, J., Ricciardi-Castagnoli, P., Dessous L'Eglise Mange, P., Martin,F. and Juillerat-Jeanneret, L (1997). Microglial cells induce cytotoxic effects toward colon carcinoma cells: mesurement of tumor cytotoxicity with a gamma-glutamyl transpeptidase assay. Int. J. Cancer 70, 69-174.

Murray, J. L., Lerner, M. P. and Nordquist, R. E (1982). Elevated gamma-glutamyl transpeptidase levels in malignant melanoma. Cancer 49, 1439-1443.[Medline]

Nakamura, H., Nakamura, K. and Yodoi, J (1997). Redox regulation of cellular activation. Annu. Rev. Immunol 15, 351-369.[Medline]

Nappi, A. J. and Vass, E (1996). Hydrogen peroxide generation associated with the oxidations of eumelanin precursors 5, 6-dihydroxyindole and 5, 6-dihydroxyindole-2-carboxylic acid. Melanoma Res 6, 341-349.[Medline]

Nose, K., Shibanuma, M., Kikuchi, K., Kageyama, H., Sakiyama, S. and Kuroki, T (1991). Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell line. Eur. J. Biochem 201, 99-106.[Medline]

Paolicchi, A., Pompella, A., Tonarelli, P., Gadducci, A., Genazzani, A. R., Zunino, F., Pratesi, G. and Tongiani, R (1996). Gamma-glutamyl transpeptidase activity in human ovarian carcinoma. Anticancer Res 16, 3053-3058.[Medline]

Paolicchi, A., Tongiani, R., Tonarelli, P., Comporti, M. and Pompella, A (1997). Gamma-glutamyl transpeptidase-dependent lipid peroxidation in isolated hepatocytes and HepG2 hepatoma cells. Free Rad. Biol. Med 22, 853-860.[Medline]

Perego, P., Giarola, M., Righetti, S. C., Supino, R., Caserini, C., Delia, D., Pierotti, M. A., Miyashita, T., Reed, J. C. and Zunino, F (1996). Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res 56, 556-562.[Abstract/Free Full Text]

Perego, P., Paolicchi, A., Tongiani, R., Pompella, A., Tonarelli, P., Carenini, N., Romanelli, S. and Zunino, F (1997). The cell-specific anti-proliferative effect of reduced glutathione is mediated by-glutamyl transpeptidase-dependent extracellular pro-oxidant reactions. Int. J. Cancer 71, 246-250.[Medline]

Pompella, A., Romani, A., Benedetti, A. and Comporti, M (1991). Loss of membrane protein thiols and lipid peroxidation in allyl alcohol hepatotoxicity. Biochem. Pharmacol 41, 1255-1259.[Medline]

Pompella, A., Cambiaggi, C., Dominici, S., Paolicchi, A., Tongiani, R. and Comporti, M (1996). Single-cell investigation by laser scanning confocal microscopy of cytochemical alterations resulting from extracellular oxidant challenge. Histochem. Cell Biol 105, 173-178.[Medline]

Powis, G., Briehl, M. and Oblong, J (1995). Redox signalling and the control of cell growth and death. Pharmac. Ther 68, 149-173.

Radi, R., Beckman, J. S., Bush, K. M. and Freeman, B. A (1991). Peroxynitrite oxidation of sulfhydryls \320 The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem 266, 4244-4250.[Abstract/Free Full Text]

Reed, D. J., Babson, J. R., Beatty, P. W., Brodie, A. E., Ellis, W. W. and Potter, D. W (1980). High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal. Biochem 106, 55-62.[Medline]

Rodeck, U (1993). Growth factor independence and growth regulatory pathways in human melanoma development. Cancer Metast. Rev 12, 219-226.[Medline]

Schmid, E., El Benna, J., Galter, D., Klein, G. and Dr\232ge, W (1998). Redox priming of the insulin receptor-chain associated with altered tyrosine kinase activity and insulin responsiveness in the absence of tyrosine autophosphorylation. FASEB J 12, 863-870.[Abstract/Free Full Text]

Schulman, J. D., Goodman, S. I., Mace, J. W., Patrick, A. D., Tietze, S. and Butler, E. J (1975). Glutathionuria: inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase. Biochem. Biophys. Res. Commun 65, 68-74.[Medline]

Sen, Ch. K (1998). Redox signaling and the emerging therapeutic potential of thiol antioxidants. Biochem. Pharmacol 55, 1747-1758.[Medline]

Seres, T., Ravichandran, V., Moriguchi, T., Rokutan, K., Thomas, J. A. and Johnston, R. B (1996). Protein S-thiolation and dethiolation during the respiratory burst in human monocytes \320 A reversible post-transational modification with potential for buffering the effects of oxidant stress. J. Immunol 156, 1973-1980.[Abstract]

Shattuck-Brandt, R. L. and Richmond, A (1997). Enhanced degradation of I- k B alpha contributes to endogenous activation of NF-B in Hs294T melanoma cells. Cancer Res 57, 3032-3039.[Abstract/Free Full Text]

Stark, A.-A., Zeiger, E. and Pagano, D. A (1993). Glutathione metabolism by-glutamyl transpeptidase leads to lipid peroxidation: characterization of the system and relevance to hepatocarcinogenesis. Carcinogenesis 14, 183-189.[Abstract/Free Full Text]

Supino, R., Mapelli, E., Sanfilippo, O. and Silvestro, L (1992). Biological and enzymatic features of human melanoma clones with different invasive potential. Melanoma Res 2, 377-384.[Medline]

Suzuki, Y. J., Forman, H. J. and Sevanian, A (1997). Oxidants as stimulators of signal transduction. Free Rad. Biol. Med 22, 269-285.[Medline]

Szatrowski, T. P. and Nathan, C. F (1991). Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 51, 794-798.[Abstract/Free Full Text]

Sze, G., Kaplowitz, N., Ookhtens, M. and Lu, S. C (1993). Bidirectional membrane transport of intact glutathione in HepG2 cells. Am. J. Physiol 28, 1128-.

T\212ger, M., Ittenson, A., Franke, A., Frey, A., Gassen, H. G. and Ansorge, S (1995). -Glutamyl transpeptidase \320 cellular expression in populations of normal human mononuclear cells and patients suffering from leukemias. Ann. Hematol 70, 237-242.[Medline]

Tate, S. S. and Meister, A (1985). -Glutamyl transpeptidase from kidney. Meth. Enzymol 113, 400-419.[Medline]

Tew, K. D., Monks, A., Barone, L., Rosser, D., Akerman, G., Montali, J. A., Wheatmley, J. B. and Schmidt, D. E. Jr (1996). Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. Mol. Pharmacol 50, 149-159.[Abstract]

Thomas, J. A., Chai, Y.-C. and Jung, C.-H (1994). Protein S-thiolation and dethiolation. Meth. Enzymol 233, 385-395.[Medline]

Toyokuni, S., Okamoto, K., Yodoi, J. and Hiai, H (1995). Persistent oxidative stress in cancer. FEBS Lett 358, 1-3.[Medline]

Tsutsumi, M., Sakamuro, D., Takada, A., Zang, S. C., Furukawa, T. and Taniguchi, N (1996). Detection of a unique gamma-glutamyl transpeptidase messenger RNA species closely related to the development of hepatocellular carcinoma in humans: a new candidate for early diagnosis of hepatocellular carcinoma. Hepatology 23, 1093-1097.[Medline]

Warren, B. S., Naylor, M. F., Winberg, L. D., Yoshimi, N., Volpe, J. P., Gimenez-Conti, I. and Slaga, T. J (1993). Induction and inhibition of tumor progression. Proc. Soc. Exp. Biol. Med 202, 9-15.[Medline]

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				C. Petti, A. Molla, C. Vegetti, S. Ferrone, A. Anichini, and M. Sensi Coexpression of NRASQ61R and BRAFV600E in Human Melanoma Cells Activates Senescence and Increases Susceptibility to Cell-Mediated Cytotoxicity. Cancer Res., July 1, 2006; 66(13): 6503 - 6511. [Abstract] [Full Text] [PDF]

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