Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Maellaro, E.
	Articles by Pompella, A.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Maellaro, E.
	Articles by Pompella, A.


Social Bookmarking

	What's this?

Andrews, N. C. and Faller, D. V (1991). A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucl. Acids Res 19, 2499-2504.[Free Full Text]

Bittinger, F., Gonz\207lez-Garc\222a, J. L., Klein, C. L., Brochhausen, C., Offner, F. and Kirkpatrick, C. J (1998). Production of superoxide by human malignant melanoma cells. Melanoma Res 8, 381-387.[Medline]

Blair, S. L., Heerdt, P., Sachar, S., Abolhoda, A., Hochwald, S., Cheng, H. and Burt, M (1997). Glutathione metabolism in patients with non-small cell lung cancers. Cancer Res 57, 152-155.[Abstract/Free Full Text]

Burdon, R. H (1995). Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Rad. Biol. Med 18, 775-794.[Medline]

Clark, S. and Konstantopoulos, N (1993). Sulfhydryl agents modulate insulin-and epidermal growth factor (EGF)-receptor kinase via reaction with intracellular receptor domains: differential effects on basal versus activated receptors. Biochem. J 292, 217-223.

Clement, M.-V. and Stamenkovic, I (1996). Superoxide anion is a natural inhibitor of Fas-mediated cell death. EMBO J 15, 216-225.[Medline]

Cotgreave, I. A. and Gerdes, R. G (1998). Recent trends in glutathione biochemistry \320 Glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation?. Biochem. Biophys. Res. Commun 242, 1-9.[Medline]

Del Bello, B., Paolicchi, A., Comporti, M., Pompella, A. and Maellaro, E (1999). Hydrogen peroxide produced during gamma-glutamyl transpeptidase activity is involved in prevention of apoptosis and maintenance of cell proliferation in U937 cells. FASEB J 13, 69-79.[Abstract/Free Full Text]

Dominici, S., Valentini, M., Maellaro, E., Del Bello, B., Paolicchi, A., Lorenzini, E., Tongiani, R., Comporti, M. and Pompella, A (1999). Redox modulation of cell surface protein thiols in U937 lymphoma cells: the role of gamma-glutamyl transpeptidase-dependent H2O2production and S-thiolation. Free Rad. Biol. Med 27, 623-635.[Medline]

Drozdz, R., Parmentier, C., Hachad, H., Leroy, P., Siest, G. and Wellman, M (1998). gamma-Glutamyltransferase dependent generation of reactive oxygen species from aglutathione/transferrin system. Free Rad. Biol. Med 25, 786-92.[Medline]

Flohe, L., Brigelius-Flohe, R., Saliou, C., Traber, M. G. and Packer, L (1997). Redox regulation of NF-kappa B activation. Free Rad. Biol. Med 22, 1115-1126.[Medline]

Gallagher, D. L., Betteridge, L. J., Patel, M. K. and Schachter, M (1993). Effect of oxidants on vascular smooth muscle proliferation. Biochem. Soc. Trans 21, 98-.

Genaro, A. M., Hortelano, S., Alvarez, A., Mart\223nez-A., C. and Bosc\210, L (1995). Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. J. Clin. Invest 95, 1884-1890.

Griffith, O. W. and Meister A (1979). Translocation of intracellular glutathione to membrane bound gamma-glutamyl transpeptidase as a discrete step in the gamma-glutamyl cycle: glutathionuria after inhibition of the transpeptidase. Proc. Nat. Acad. Sci. USA 76, 268-279.[Abstract/Free Full Text]

Griffith, O. W. and Tate, S. S (1980). The apparent glutathione-oxidase activity of-glutamyl transpeptidase. J. Biol. Chem 255, 5011-5014.[Abstract/Free Full Text]

Hanigan, M. H. and Frierson, H. F. Jr (1996). Immunohistochemical detection of gamma-glutamyl transpeptidase in normal human tissue. J. Histochem. Cytochem 44, 1101-1108.[Abstract]

Herbert, J. M., Bono, F. and Savi, P (1996). The mitogenic effect of H2O2for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor. FEBS Lett 395, 43-47.[Medline]

Higgins, K. A., Perez, J. R., Coleman, T. A., Dorshkind, K., McComas, W. A., Sarmiento, U. M., Rosen, C. A. and Narayanan, R (1993). Antisense inhibition of the p65 subunit of NF-B blocks tumorigenicity and causes tumor regeression. Proc. Nat. Acad. Sci. USA 90, 9901-9905.[Abstract/Free Full Text]

Hochwald, S. N., Harrison, L. E., Rose, D. M., Anderson, M. and Burt, M. E (1997). Elevation of glutathione and related enzyme activities in high-grade and metastatic extremity soft tissue sarcoma. Ann. Surg. Oncol 4, 303-309.[Medline]

Huang, R. P., Wu, J. X., Fan, Y. and Adamson, E. D (1996). UV activates growth factor receptors via reactive oxygen intermediates. J. Cell Biol 133, 211-220.[Abstract/Free Full Text]

Huseby, N. E. and Str\232mme, J. H (1974). Practical points regarding routine determination of gamma-glutamyl transferase (-GT) in serum with a kinetic method at 37degC. Scand.J. Clin. Lab. Invest 34, 357-361.[Medline]

Lander, H. M (1997). An essential role for free radicals and derived species in signal transduction. FASEB J 11, 118-124.[Abstract]

Lash, L. H. and Jones, D. P (1986). Purification and properties of the membranal thiol oxidase from porcine kidney. Arch. Biochem. Biophys 247, 120-130.[Medline]

Maellaro, E., Del Bello, B. and Comporti, M (1996). Protection by ascorbate against apoptosis of thymocytes: implications of ascorbate-induced nonlethal oxidative stress and poly(ADP-ribosyl)ation. Exp. Cell Res 226, 105-113.[Medline]

Melezinek, I., Borovansky, J., Elleder, M. and Bubnova, E (1998). Tumour tissue is a source of gamma-glutamyl transpeptidase sialoform in the sera of melanoma-bearing mice. Melanoma Res 8, 39-45.[Medline]

Mohanty, J. G., Jaffe, J. S., Shulman, E. S. and Raible, D. G (1997). A highly sensitive fluorescent micro-assay of H2O2release from activated human leukocytes using a dihydroxyphenoxazine derivative. J. Immunol. Meth 202, 133-141.[Medline]

Monteiro, H. P. and Stern, A (1996). Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways. Free Rad. Biol. Med 21, 323-333.[Medline]

Murata, J., Ricciardi-Castagnoli, P., Dessous L'Eglise Mange, P., Martin,F. and Juillerat-Jeanneret, L (1997). Microglial cells induce cytotoxic effects toward colon carcinoma cells: mesurement of tumor cytotoxicity with a gamma-glutamyl transpeptidase assay. Int. J. Cancer 70, 69-174.

Murray, J. L., Lerner, M. P. and Nordquist, R. E (1982). Elevated gamma-glutamyl transpeptidase levels in malignant melanoma. Cancer 49, 1439-1443.[Medline]

Nakamura, H., Nakamura, K. and Yodoi, J (1997). Redox regulation of cellular activation. Annu. Rev. Immunol 15, 351-369.[Medline]

Nappi, A. J. and Vass, E (1996). Hydrogen peroxide generation associated with the oxidations of eumelanin precursors 5, 6-dihydroxyindole and 5, 6-dihydroxyindole-2-carboxylic acid. Melanoma Res 6, 341-349.[Medline]

Nose, K., Shibanuma, M., Kikuchi, K., Kageyama, H., Sakiyama, S. and Kuroki, T (1991). Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell line. Eur. J. Biochem 201, 99-106.[Medline]

Paolicchi, A., Pompella, A., Tonarelli, P., Gadducci, A., Genazzani, A. R., Zunino, F., Pratesi, G. and Tongiani, R (1996). Gamma-glutamyl transpeptidase activity in human ovarian carcinoma. Anticancer Res 16, 3053-3058.[Medline]

Paolicchi, A., Tongiani, R., Tonarelli, P., Comporti, M. and Pompella, A (1997). Gamma-glutamyl transpeptidase-dependent lipid peroxidation in isolated hepatocytes and HepG2 hepatoma cells. Free Rad. Biol. Med 22, 853-860.[Medline]

Perego, P., Giarola, M., Righetti, S. C., Supino, R., Caserini, C., Delia, D., Pierotti, M. A., Miyashita, T., Reed, J. C. and Zunino, F (1996). Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res 56, 556-562.[Abstract/Free Full Text]

Perego, P., Paolicchi, A., Tongiani, R., Pompella, A., Tonarelli, P., Carenini, N., Romanelli, S. and Zunino, F (1997). The cell-specific anti-proliferative effect of reduced glutathione is mediated by-glutamyl transpeptidase-dependent extracellular pro-oxidant reactions. Int. J. Cancer 71, 246-250.[Medline]

Pompella, A., Romani, A., Benedetti, A. and Comporti, M (1991). Loss of membrane protein thiols and lipid peroxidation in allyl alcohol hepatotoxicity. Biochem. Pharmacol 41, 1255-1259.[Medline]

Pompella, A., Cambiaggi, C., Dominici, S., Paolicchi, A., Tongiani, R. and Comporti, M (1996). Single-cell investigation by laser scanning confocal microscopy of cytochemical alterations resulting from extracellular oxidant challenge. Histochem. Cell Biol 105, 173-178.[Medline]

Powis, G., Briehl, M. and Oblong, J (1995). Redox signalling and the control of cell growth and death. Pharmac. Ther 68, 149-173.

Radi, R., Beckman, J. S., Bush, K. M. and Freeman, B. A (1991). Peroxynitrite oxidation of sulfhydryls \320 The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem 266, 4244-4250.[Abstract/Free Full Text]

Reed, D. J., Babson, J. R., Beatty, P. W., Brodie, A. E., Ellis, W. W. and Potter, D. W (1980). High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides. Anal. Biochem 106, 55-62.[Medline]

Rodeck, U (1993). Growth factor independence and growth regulatory pathways in human melanoma development. Cancer Metast. Rev 12, 219-226.[Medline]

Schmid, E., El Benna, J., Galter, D., Klein, G. and Dr\232ge, W (1998). Redox priming of the insulin receptor-chain associated with altered tyrosine kinase activity and insulin responsiveness in the absence of tyrosine autophosphorylation. FASEB J 12, 863-870.[Abstract/Free Full Text]

Schulman, J. D., Goodman, S. I., Mace, J. W., Patrick, A. D., Tietze, S. and Butler, E. J (1975). Glutathionuria: inborn error of metabolism due to tissue deficiency of gamma-glutamyl transpeptidase. Biochem. Biophys. Res. Commun 65, 68-74.[Medline]

Sen, Ch. K (1998). Redox signaling and the emerging therapeutic potential of thiol antioxidants. Biochem. Pharmacol 55, 1747-1758.[Medline]

Seres, T., Ravichandran, V., Moriguchi, T., Rokutan, K., Thomas, J. A. and Johnston, R. B (1996). Protein S-thiolation and dethiolation during the respiratory burst in human monocytes \320 A reversible post-transational modification with potential for buffering the effects of oxidant stress. J. Immunol 156, 1973-1980.[Abstract]

Shattuck-Brandt, R. L. and Richmond, A (1997). Enhanced degradation of I- k B alpha contributes to endogenous activation of NF-B in Hs294T melanoma cells. Cancer Res 57, 3032-3039.[Abstract/Free Full Text]

Stark, A.-A., Zeiger, E. and Pagano, D. A (1993). Glutathione metabolism by-glutamyl transpeptidase leads to lipid peroxidation: characterization of the system and relevance to hepatocarcinogenesis. Carcinogenesis 14, 183-189.[Abstract/Free Full Text]

Supino, R., Mapelli, E., Sanfilippo, O. and Silvestro, L (1992). Biological and enzymatic features of human melanoma clones with different invasive potential. Melanoma Res 2, 377-384.[Medline]

Suzuki, Y. J., Forman, H. J. and Sevanian, A (1997). Oxidants as stimulators of signal transduction. Free Rad. Biol. Med 22, 269-285.[Medline]

Szatrowski, T. P. and Nathan, C. F (1991). Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res 51, 794-798.[Abstract/Free Full Text]

Sze, G., Kaplowitz, N., Ookhtens, M. and Lu, S. C (1993). Bidirectional membrane transport of intact glutathione in HepG2 cells. Am. J. Physiol 28, 1128-.

T\212ger, M., Ittenson, A., Franke, A., Frey, A., Gassen, H. G. and Ansorge, S (1995). -Glutamyl transpeptidase \320 cellular expression in populations of normal human mononuclear cells and patients suffering from leukemias. Ann. Hematol 70, 237-242.[Medline]

Tate, S. S. and Meister, A (1985). -Glutamyl transpeptidase from kidney. Meth. Enzymol 113, 400-419.[Medline]

Tew, K. D., Monks, A., Barone, L., Rosser, D., Akerman, G., Montali, J. A., Wheatmley, J. B. and Schmidt, D. E. Jr (1996). Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. Mol. Pharmacol 50, 149-159.[Abstract]

Thomas, J. A., Chai, Y.-C. and Jung, C.-H (1994). Protein S-thiolation and dethiolation. Meth. Enzymol 233, 385-395.[Medline]

Toyokuni, S., Okamoto, K., Yodoi, J. and Hiai, H (1995). Persistent oxidative stress in cancer. FEBS Lett 358, 1-3.[Medline]

Tsutsumi, M., Sakamuro, D., Takada, A., Zang, S. C., Furukawa, T. and Taniguchi, N (1996). Detection of a unique gamma-glutamyl transpeptidase messenger RNA species closely related to the development of hepatocellular carcinoma in humans: a new candidate for early diagnosis of hepatocellular carcinoma. Hepatology 23, 1093-1097.[Medline]

Warren, B. S., Naylor, M. F., Winberg, L. D., Yoshimi, N., Volpe, J. P., Gimenez-Conti, I. and Slaga, T. J (1993). Induction and inhibition of tumor progression. Proc. Soc. Exp. Biol. Med 202, 9-15.[Medline]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

H. Z. Ozsoy, N. Sivasubramanian, E. D. Wieder, S. Pedersen, and D. L. Mann
Oxidative Stress Promotes Ligand-independent and Enhanced Ligand-dependent Tumor Necrosis Factor Receptor Signaling
J. Biol. Chem., August 22, 2008; 283(34): 23419 - 23428.
[Abstract] [Full Text] [PDF]

D. Giustarini, I. Dalle-Donne, S. Lorenzini, A. Milzani, and R. Rossi
Age-related influence on thiol, disulfide, and protein-mixed disulfide levels in human plasma.
J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2006; 61(10): 1030 - 1038.
[Abstract] [Full Text] [PDF]

C. Petti, A. Molla, C. Vegetti, S. Ferrone, A. Anichini, and M. Sensi
Coexpression of NRASQ61R and BRAFV600E in Human Melanoma Cells Activates Senescence and Increases Susceptibility to Cell-Mediated Cytotoxicity.
Cancer Res., July 1, 2006; 66(13): 6503 - 6511.
[Abstract] [Full Text] [PDF]

E. Ruttmann, L. J. Brant, H. Concin, G. Diem, K. Rapp, H. Ulmer, and the Vorarlberg Health Monitoring and Promotion Pro
{gamma}-Glutamyltransferase as a Risk Factor for Cardiovascular Disease Mortality: An Epidemiological Investigation in a Cohort of 163 944 Austrian Adults
Circulation, October 4, 2005; 112(14): 2130 - 2137.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Maellaro, E.

Articles by Pompella, A.

Search for Related Content

PubMed

PubMed Citation

Articles by Maellaro, E.

Articles by Pompella, A.

Social Bookmarking

What's this?

				D. Giustarini, I. Dalle-Donne, S. Lorenzini, A. Milzani, and R. Rossi Age-related influence on thiol, disulfide, and protein-mixed disulfide levels in human plasma. J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2006; 61(10): 1030 - 1038. [Abstract] [Full Text] [PDF]

				C. Petti, A. Molla, C. Vegetti, S. Ferrone, A. Anichini, and M. Sensi Coexpression of NRASQ61R and BRAFV600E in Human Melanoma Cells Activates Senescence and Increases Susceptibility to Cell-Mediated Cytotoxicity. Cancer Res., July 1, 2006; 66(13): 6503 - 6511. [Abstract] [Full Text] [PDF]

				E. Ruttmann, L. J. Brant, H. Concin, G. Diem, K. Rapp, H. Ulmer, and the Vorarlberg Health Monitoring and Promotion Pro {gamma}-Glutamyltransferase as a Risk Factor for Cardiovascular Disease Mortality: An Epidemiological Investigation in a Cohort of 163 944 Austrian Adults Circulation, October 4, 2005; 112(14): 2130 - 2137. [Abstract] [Full Text] [PDF]