Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages

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Aderem, A. and Underhill, D. M (1999). Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol 17, 593-623.[Medline]

Albillos, A., Dernick, G., Horstmann, H., Almers, W., Alvarez de Toledo, G. and Lindau, M (1997). The exocytotic event in chromaffin cells revealed by patch amperometry. Nature 389, 509-512.[Medline]

Alpuche-Aranda, C., Racoosin, E. L., Swanson, J. A. and Miller, S. I (1994). Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes. J. Exp. Med 179, 601-608.[Abstract/Free Full Text]

Alvarez de Toledo, G., Fernandez-Chacon, R. and Fernandez, J. M (1993). Release of secretory products during transient vesicle fusion. Nature 363, 554-558.[Medline]

Alvarez-Dominguez, C., Barbieri, A. M., Beron, W., Wandinger-Ness, A. and Stahl, P. D (1996). Phagocytosed live Listeria monocytogenes influences rab5-regulated in vitro phagosome-endosome fusion. J. Biol. Chem 271, 13834-13843.[Abstract/Free Full Text]

Alvarez-Dominguez, C. and Stahl, P. D (1999). Increased expression of Rab5a correlates directly with accelerated maturation of Listeria monocytogenes phagosomes. J. Biol. Chem 274, 11459-11462.[Abstract/Free Full Text]

Appel, R. D., Palagi, P. M., Walther, D., Vargas, J. R., Sanchez, J. C., Ravier, F., Pasquali, C. and Hochstrasser, D. F (1997). Melanie II\320a third-generation software package for analysis of two-dimensional electrophoresis images: I. Features and user interface. Electrophoresis 18, 2724-2734.[Medline]

Araki, N., Johnson, M. T. and Swanson, J. A (1996). A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages. J. Cell Biol 135, 1249-1260.[Abstract/Free Full Text]

Berthiaume, E. P., Medina, C. and Swanson, J. A (1995). Molecular size-fractionation during endocytosis in macrophages. J. Cell Biol 129, 989-998.[Abstract/Free Full Text]

Blocker, A., Severin, F. F., Burkhardt, J. K., Bingham, J. B., Yu, H., Olivo, J. C., Schroer, T. A., Hyman, A. A. and Griffiths, G (1997). Molecular requirements for bi-directional movement of phagosomes along microtubules. J. Cell Biol 137, 113-129.[Abstract/Free Full Text]

Blocker, A., Griffiths, G., Olivo, J. C., Hyman, A. A. and Severin, F. F (1998). A role for microtubule dynamics in phagosome movement. J. Cell Sci 111, 303-312.[Abstract]

Bucci, C., Parton, R. G., Mather, I. H., Stunnenberg, H., Simons, K., Hofflack, B. and Zerial, M (1992). The small GTPase rab 5 functions as a regulatory factor in the early endocytic pathway. Cell 70, 715-728.[Medline]

Caron, E. and Hall, A (1998). Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282, 1717-1721.[Abstract/Free Full Text]

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K. and Zerial, M (1990). Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments. Cell 62, 317-329.[Medline]

Clague, M. J., Urbe, S., Aniento, F. and Gruenberg, J (1994). Vacuolar ATPase activity is required for endosomal carrier vesicle formation. J. Biol. Chem 269, 21-24.[Abstract/Free Full Text]

Claus, V., Jahraus, A., Tjelle, T., Berg, T., Kirschke, H., Faulstich, H. and Griffiths, G (1998). Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages. Enrichment of cathepsin H in early endosomes. J. Biol. Chem 273, 9842-9851.[Abstract/Free Full Text]

D'Arrigo, A., Bucci, C., Toh, B. H. and Stenmark, H (1997). Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes. Eur. J. Cell Biol 72, 95-103.[Medline]

Desjardins, M., Huber, L. A., Parton, R. G. and Griffiths, G (1994). Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J. Cell Biol 124, 677-688.[Abstract/Free Full Text]

Desjardins, M., Celis, J. E., van Meer, G., Dieplinger, H., Jahraus, A., Griffiths, G. and Huber, L. A (1994). Molecular characterization of phagosomes. J. Biol. Chem 269, 32194-32200.[Abstract/Free Full Text]

Desjardins, M. and Descoteaux, A (1997). Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan. J. Exp. Med 185, 2061-2068.[Abstract/Free Full Text]

Desjardins, M., Nzala, N. N., Corsini, R. and Rondeau, C (1997). Maturation of phagosomes is accompanied by changes in their fusion properties and size-selective acquisition of solute materials from endosomes. J. Cell Sci 110, 2303-2314.[Abstract]

Evan, G. I., Lewis, G. K., Ramsay, G. and Bishop, J. M (1985). Isolation of monoclonal antibodies specific for human c- myc proto-oncogene product. Mol. Cell. Biol 5, 3610-3616.[Abstract/Free Full Text]

Feng, Y., Press, B. and Wandinger-Ness, A (1995). Rab 7: an important regulator of late endocytic membrane traffic. J. Cell Biol 131, 1435-1452.[Abstract/Free Full Text]

Funato, K., Beron, W., Yang, C. Z., Mukhopadhyay, A. and Stahl, P. D (1997). Reconstitution of phagosome-lysosome fusion in streptolysin O-permeabilized cells. J. Biol. Chem 272, 16147-16151.[Abstract/Free Full Text]

Geppert, M. and Sudhof, T. C (1998). RAB3 and synaptotagmin: the yin and yang of synaptic membrane fusion. Annu. Rev. Neurosci 21, 75-95.[Medline]

Gonzalez, L. Jr and Scheller, R. H (1999). Regulation of membrane trafficking: structural insights from a Rab/effector complex. Cell 96, 755-758.[Medline]

Gorvel, J. P., Chavrier, P., Zerial, M. and Gruenberg, J (1991). rab5 controls early endosome fusion in vitro. Cell 64, 915-925.[Medline]

Hackam, D. J., Rotstein, O. D., Bennett, M. K., Klip, A., Grinstein, S. and Manolson, M. F (1996). Characterization and subcellular localization of target membrane soluble NSF attachment protein receptors (t-SNAREs) in macrophages. Syntaxins 2, 3, and 4 are present on phagosomal membranes. J. Immunol 156, 4377-4383.[Abstract]

Hackam, D. J., Rotstein, O. D., Sjolin, C., Schreiber, A. D., Trimble, W. S. and Grinstein, S (1998). v-SNARE-dependent secretion is required for phagocytosis. Proc. Nat. Acad. Sci. USA 95, 11691-11696.[Abstract/Free Full Text]

Jahraus, A., Storrie, B., Griffiths, G. and Desjardins, M (1994). Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment. J. Cell Sci 107, 145-157.[Abstract]

Jahraus, A., Tjelle, T. E., Berg, T., Habermann, A., Storrie, B., Ullrich, O. and Griffiths, G (1998). In vitro fusion of phagosomes with different endocytic organelles from J774 macrophages. J. Biol. Chem 273, 30379-30390.[Abstract/Free Full Text]

Kornfeld, S. and Mellman, I (1989). The biogenesis of lysosomes. Annu. Rev. Cell Biol 5, 483-525.

McBride, H. M., Rybin, V., Murphy, C., Giner, A., Teasdale, R. and Zerial, M (1999). Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13. Cell 98, 377-386.[Medline]

Mellman, I (1992). The importance of being acid: the role of acidification in intracellular membrane traffic. J. Exp. Biol 172, 39-45.[Free Full Text]

Meresse, S., Gorvel, J. P. and Chavrier, P (1995). The rab7 GTPase resides on a vesicular compartment connected to lysosomes. J. Cell Sci 108, 3349-3358.[Abstract]

Mills, I. G., Jones, A. T. and Clague, M. J (1999). Regulation of endosome fusion. Mol. Membr. Biol 16, 73-79.[Medline]

Mohrmann, K. and van der Sluijs, P (1999). Regulation of membrane transport through the endocytic pathway by rabGTPases. Mol. Membr. Biol 16, 81-87.[Medline]

Novick, P. and Zerial, M (1997). The diversity of Rab proteins in vesicle transport. Curr. Opin. Cell Biol 9, 496-504.[Medline]

Pitt, A., Mayorga, L. S., Stahl, P. D. and Schwartz, A. L (1992). Alterations in the protein composition of maturing phagosomes. J. Clin. Invest 90, 1978-1983.

Pizarro-Cerd\210, J., Moreno, E., Desjardins, M. and Gorvel, J. P (1997). When intracellular pathogens invade the frontiers of cell biology and immunology. Histol. Histopathol 12, 1027-1038.[Medline]

Rabilloud, T., Kieffer, S., Procaccio, V., Louwagie, M., Courchesne, P. L., Patterson, S. D., Martinez, P., Garin, J. and Lunardi, J (1998). Two-dimensional electrophoresis of human placental mitochondria and protein identification by mass spectrometry: toward a human mitochondrial proteome. Electrophoresis 19, 1006-1014.[Medline]

Rabinowitz, S., Horstmann, H., Gordon, S. and Griffiths, G (1992). Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages. J. Cell Biol 116, 95-112.[Abstract/Free Full Text]

Rauma, T., Tuukkanen, J., Bergelson, J. M., Denning, G. and Hautala, T (1999). Rab5 GTPase regulates adenovirus endocytosis. J. Virol 73, 9664-9668.[Abstract/Free Full Text]

Rees, S., Coote, J., Stables, J., Goodson, S., Harris, S. and Lee, M. G (1996). Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotics-resistant cells to express recombinant protein. BioTechniques 20, 102-110.

Roberts, R. L., Barbieri, M. A., Pryse, K. M., Chua, M., Morisaki, J. H. and Stahl, P. D (1999). Endosome fusion in living cells overexpressing GFP-rab5. J. Cell Sci 112, 3667-3675.[Abstract]

Rybin, V., Ullrich, O., Rubino, M., Alexandrov, K., Simon, I., Seabra, C., Goody, R. and Zerial, M (1996). GTPase activity of Rab5 acts as a timer for endocytic membrane fusion. Nature 383, 266-269.[Medline]

St-Denis, A., Caouras, V., Gervais, F. and Descoteaux, A (1999). Role of protein kinase C-in the control of infection by intracellular pathogens in macrophages. J. Immunol 163, 5505-5511.[Abstract/Free Full Text]

Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J. M., Brech, A., Callaghan, J., Toh, B. H., Murphy, C., Zerial, M. and Stenmark, H (1998). EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature 394, 494-498.[Medline]

Sinai, A. P. and Joiner, K. A (1997). Safe haven: the cell biology of nonfusogenic pathogen vacuoles. Annu. Rev. Microbiol 51, 415-462.[Medline]

Sonnichsen, B., De Renzis, S., Nielsen, E., Rietdorf, J. and Zerial, M (2000). Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11. J. Cell Biol 149, 901-914.[Abstract/Free Full Text]

Stacey, K. J., Ross, I. L. and Hume, D. A (1993). Electroporation and DNA-dependent cell death in murine macrophages. Immunol. Cell Biol 71, 75-85.

Stenmark, H., Parton, R. G., Steele-Mortimer, O., Lutcke, A., Gruenberg, J. and Zerial, M (1994). Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. EMBO J 13, 1287-1296.[Medline]

Stenmark, H., Vitale, G., Ullrich, O. and Zerial, M (1995). Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion. Cell 83, 423-432.[Medline]

Storrie, B. and Desjardins, M (1996). The biogenesis of lysosomes: Is it a kiss and run, continuous fusion and fission process?. BioEssays 18, 895-903.[Medline]

Sturgill-Koszycki, S., Schlesinger, P. H., Chakraborty, P., Haddix, P. L., Collins, H. L., Fok, A. K., Allen, R. D., Gluck, S. L., Heuser, J. and Russell, D. G (1994). Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263, 678-681.[Abstract/Free Full Text]

Ullrich, H. J., Beatty, W. L. and Russell, D. G (1999). Direct delivery of procathepsin D to phagosomes: implications for phagosome biogenesis and parasitism by Mycobacterium. Eur. J. Cell Biol 78, 739-748.[Medline]

van Deurs, B., Holm, P. K. and Sandvig, K (1996). Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells. Eur. J. Cell Biol 69, 343-350.[Medline]

van Weert, A. W., Dunn, K. W., Gueze, H. J., Maxfield, F. R. and Stoorvogel, W (1995). Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J. Cell Biol 130, 821-834.[Abstract/Free Full Text]

Veras, P. S., de Chastellier, C. and Rabinovitch, M (1992). Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis. J. Exp. Med 176, 639-646.[Abstract/Free Full Text]

Veras, P. S., de Chastellier, C., Moreau, M. F., Villiers, V., Thibon, M., Mattei, D. and Rabinovitch, M (1994). Fusion between large phagocytic vesicles: targeting of yeast and other particulates to phagolysosomes that shelter the bacterium Coxiella burnetii or the protozoan Leishmania amazonensis in Chinese hamster ovary cells. J. Cell Sci 107, 3065-3076.[Abstract]

Via, L. E., Deretic, D., Ulmer, R. J., Hibler, N. S., Huber, L. A. and Deretic, V (1997). Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7. J. Biol. Chem 272, 13326-13331.[Abstract/Free Full Text]

Vitelli, R., Santillo, M., Lattero, D., Chiariello, M., Bifulco, M., Bruni, C. B. and Bucci, C (1997). Role of the small GTPase Rab7 in the late endocytic pathway. J. Biol. Chem 272, 4391-4397.[Abstract/Free Full Text]

Wang, Y. L. and Goren, M. B (1987). Differential and sequential delivery of fluorescent lysosomal probes into phagosomes in mouse peritoneal macrophages. J. Cell Biol 104, 1749-1754.[Abstract/Free Full Text]

Warren, G. and Mellman, I (1999). Bulk flow redux?. Cell 98, 125-127.[Medline]

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