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A. Vararattanavech, X. Lin, J. Torres, and S.-M. Tan
Disruption of the Integrin {alpha}L{beta}2 Transmembrane Domain Interface by {beta}2 Thr-686 Mutation Activates {alpha}L{beta}2 and Promotes Micro-clustering of the {alpha}L Subunits
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N. Prevost, J. V. Mitsios, H. Kato, J. E. Burke, E. A. Dennis, T. Shimizu, and S. J. Shattil
Group IVA cytosolic phospholipase A2 (cPLA2{alpha}) and integrin {alpha}IIb{beta}3 reinforce each other's functions during {alpha}IIb{beta}3 signaling in platelets
Blood, January 8, 2009; 113(2): 447 - 457.
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D. A. Chudakova, Y. H. Zeidan, B. W. Wheeler, J. Yu, S. A. Novgorodov, M. S. Kindy, Y. A. Hannun, and T. I. Gudz
Integrin-associated Lyn Kinase Promotes Cell Survival by Suppressing Acid Sphingomyelinase Activity
J. Biol. Chem., October 24, 2008; 283(43): 28806 - 28816.
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N. Watanabe, L. Bodin, M. Pandey, M. Krause, S. Coughlin, V. A. Boussiotis, M. H. Ginsberg, and S. J. Shattil
Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin {alpha}IIb{beta}3
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The Talin Rod IBS2 {alpha}-Helix Interacts with the {beta}3 Integrin Cytoplasmic Tail Membrane-proximal Helix by Establishing Charge Complementary Salt Bridges
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H. Epple, V. Cremasco, K. Zhang, D. Mao, G. D. Longmore, and R. Faccio
Phospholipase C{gamma}2 Modulates Integrin Signaling in the Osteoclast by Affecting the Localization and Activation of Src Kinase
Mol. Cell. Biol., June 1, 2008; 28(11): 3610 - 3622.
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F. J. Conti, A. Felder, S. Monkley, M. Schwander, M. R. Wood, R. Lieber, D. Critchley, and U. Muller
Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle
Development, June 1, 2008; 135(11): 2043 - 2053.
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K. B. Reddy, D. M. Smith, and E. F. Plow
Analysis of Fyn function in hemostasis and {alpha}IIb{beta}3-integrin signaling
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M. Waldeck-Weiermair, C. Zoratti, K. Osibow, N. Balenga, E. Goessnitzer, M. Waldhoer, R. Malli, and W. F. Graier
Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression
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C. L. Oxley, N. J. Anthis, E. D. Lowe, I. Vakonakis, I. D. Campbell, and L. Wegener
An Integrin Phosphorylation Switch: THE EFFECT OF {beta}3 INTEGRIN TAIL PHOSPHORYLATION ON DOK1 AND TALIN BINDING
J. Biol. Chem., February 29, 2008; 283(9): 5420 - 5426.
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JEMHome page
N. A. Morin, P. W. Oakes, Y.-M. Hyun, D. Lee, Y. E. Chin, M. R. King, T. A. Springer, M. Shimaoka, J. X. Tang, J. S. Reichner, et al.
Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration
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T. Tran, K. Ens-Blackie, E. S. Rector, G. L. Stelmack, K. D. McNeill, G. Tarone, W. T. Gerthoffer, H. Unruh, and A. J. Halayko
Laminin-Binding Integrin {alpha}7 Is Required for Contractile Phenotype Expression by Human Airway Myocytes
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Anti-Inflammatory Effects of {alpha}v Integrin Antagonism in Acute Kidney Allograft Rejection
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G. W. Prager, C. C. Feral, C. Kim, J. Han, and M. H. Ginsberg
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X. Shi, Y.-Q. Ma, Y. Tu, K. Chen, S. Wu, K. Fukuda, J. Qin, E. F. Plow, and C. Wu
The MIG-2/Integrin Interaction Strengthens Cell-Matrix Adhesion and Modulates Cell Motility
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E. A. Evans and D. A. Calderwood
Forces and Bond Dynamics in Cell Adhesion
Science, May 25, 2007; 316(5828): 1148 - 1153.
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S. Stefansson, E. J. Su, S. Ishigami, J. M. Cale, Y. Gao, N. Gorlatova, and D. A. Lawrence
The Contributions of Integrin Affinity and Integrin-Cytoskeletal Engagement in Endothelial and Smooth Muscle Cell Adhesion to Vitronectin
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A. S. Yatsenko, E. E. Gray, H. R. Shcherbata, L. B. Patterson, V. D. Sood, M. M. Kucherenko, D. Baker, and H. Ruohola-Baker
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
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BloodHome page
Z. Zou, H. Chen, A. A. Schmaier, R. O. Hynes, and M. L. Kahn
Structure-function analysis reveals discrete {beta}3 integrin inside-out and outside-in signaling pathways in platelets
Blood, April 15, 2007; 109(8): 3284 - 3290.
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A. Cambi, B. Joosten, M. Koopman, F. de Lange, I. Beeren, R. Torensma, J. A. Fransen, M. Garcia-Parajo, F. N. van Leeuwen, and C. G. Figdor
Organization of the Integrin LFA-1 in Nanoclusters Regulates Its Activity
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A. P. Yamniuk, H. Ishida, and H. J. Vogel
The Interaction between Calcium- and Integrin-binding Protein 1 and the {alpha}IIb Integrin Cytoplasmic Domain Involves a Novel C-terminal Displacement Mechanism
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R. E. Conway, N. Petrovic, Z. Li, W. Heston, D. Wu, and L. H. Shapiro
Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction.
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E. Boulter, D. Grall, S. Cagnol, and E. Van Obberghen-Schilling
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B. P. Levi, A. S. Ghabrial, and M. A. Krasnow
Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization
Development, June 15, 2006; 133(12): 2383 - 2393.
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G. Tanentzapf, M. D. Martin-Bermudo, M. S. Hicks, and N. H. Brown
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E. G. Arias-Salgado, S. Lizano, S. J. Shattil, and M. H. Ginsberg
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A talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes
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D. Garcia-Bernal, N. Wright, E. Sotillo-Mallo, C. Nombela-Arrieta, J. V. Stein, X. R. Bustelo, and J. Teixido
Vav1 and Rac Control Chemokine-promoted T Lymphocyte Adhesion Mediated by the Integrin {alpha}4{beta}1
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S.J. Williams, B.G. White, and D.J. MacPhee
Expression of {alpha}5 Integrin (Itga5) Is Elevated in the Rat Myometrium During Late Pregnancy and Labor: Implications for Development of a Mechanical Syncytium
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C. Prunier and P. H. Howe
Disabled-2 (Dab2) Is Required for Transforming Growth Factor {beta}-induced Epithelial to Mesenchymal Transition (EMT)
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D. A. Solovjov, E. Pluskota, and E. F. Plow
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N. C. Henderson, E. A. Collis, A. C. Mackinnon, K. J. Simpson, C. Haslett, R. Zent, M. Ginsberg, and T. Sethi
CD98hc (SLC3A2) Interaction with {beta}1 Integrins Is Required for Transformation
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S. Pereira, H. Zhang, T. Takai, and C. A. Lowell
The Inhibitory Receptor PIR-B Negatively Regulates Neutrophil and Macrophage Integrin Signaling
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H. R. Kim, M. Hoque, and C.-M. Hai
Cholinergic receptor-mediated differential cytoskeletal recruitment of actin- and integrin-binding proteins in intact airway smooth muscle
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D. D. Mruk and C. Y. Cheng
Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis
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M. C. Brown and C. E. Turner
Paxillin: Adapting to Change
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NrCAM Coupling to the Cytoskeleton Depends on Multiple Protein Domains and Partitioning into Lipid Rafts
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V. Vouret-Craviari, E. Boulter, D. Grall, C. Matthews, and E. Van Obberghen-Schilling
ILK is required for the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells
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M. Puig-de-Morales, E. Millet, B. Fabry, D. Navajas, N. Wang, J. P. Butler, and J. J. Fredberg
Cytoskeletal mechanics in adherent human airway smooth muscle cells: probe specificity and scaling of protein-protein dynamics
Am J Physiol Cell Physiol, September 1, 2004; 287(3): C643 - C654.
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The Phosphorylation of Vinculin on Tyrosine Residues 100 and 1065, Mediated by Src Kinases, Affects Cell Spreading
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M. K.Y. Siu and C. Y. Cheng
Extracellular Matrix: Recent Advances on Its Role in Junction Dynamics in the Seminiferous Epithelium During Spermatogenesis
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A. L. Jannuzi, T. A. Bunch, R. F. West, and D. L. Brower
Identification of Integrin {beta} Subunit Mutations that Alter Heterodimer Function In Situ
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T. Samson, N. Smyth, S. Janetzky, O. Wendler, J. M. Muller, R. Schule, H. von der Mark, K. von der Mark, and V. Wixler
The LIM-only Proteins FHL2 and FHL3 Interact with {alpha}- and {beta}-Subunits of the Muscle {alpha}7{beta}1 Integrin Receptor
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H. Huang, R. D. Kamm, and R. T. Lee
Cell mechanics and mechanotransduction: pathways, probes, and physiology
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A. Gustavsson, M. Yuan, and M. Fallman
Temporal Dissection of {beta}1-Integrin Signaling Indicates a Role for p130Cas-Crk in Filopodia Formation
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Affixin interacts with {alpha}-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction
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L. Tremuth, S. Kreis, C. Melchior, J. Hoebeke, P. Ronde, S. Plancon, K. Takeda, and N. Kieffer
A Fluorescence Cell Biology Approach to Map the Second Integrin-binding Site of Talin to a 130-Amino Acid Sequence within the Rod Domain
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S. Denti, A. Sirri, A. Cheli, L. Rogge, G. Innamorati, S. Putignano, M. Fabbri, R. Pardi, and E. Bianchi
RanBPM Is a Phosphoprotein That Associates with the Plasma Membrane and Interacts with the Integrin LFA-1
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O. Vinogradova, J. Vaynberg, X. Kong, T. A. Haas, E. F. Plow, and J. Qin
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N. Hogg, M. Laschinger, K. Giles, and A. McDowall
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{beta}1 Integrin/Focal Adhesion Kinase-mediated Signaling Induces Intercellular Adhesion Molecule 1 and Receptor Activator of Nuclear Factor {kappa}B Ligand on Osteoblasts and Osteoclast Maturation
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G. Giannone, G. Jiang, D. H. Sutton, D. R. Critchley, and M. P. Sheetz
Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation
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E. J. Cram, S. G. Clark, and J. E. Schwarzbauer
Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans
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M. Kim, C. V. Carman, and T. A. Springer
Bidirectional Transmembrane Signaling by Cytoplasmic Domain Separation in Integrins
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Y.-M. Xiong, J. Chen, and L. Zhang
Modulation of CD11b/CD18 Adhesive Activity by Its Extracellular, Membrane-Proximal Regions
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Latent Transforming Growth Factor-{beta}-binding Protein 2 Is an Adhesion Protein for Melanoma Cells
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D. M. Rose, S. Liu, D. G. Woodside, J. Han, D. D. Schlaepfer, and M. H. Ginsberg
Paxillin Binding to the {alpha}4 Integrin Subunit Stimulates LFA-1 (Integrin {alpha}L{beta}2)-Dependent T Cell Migration by Augmenting the Activation of Focal Adhesion Kinase/Proline-Rich Tyrosine Kinase-2
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Neuregulin-1 Enhances Motility and Migration of Human Astrocytic Glioma Cells
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Specific beta 1 Integrin Site Selectively Regulates Akt/Protein Kinase B Signaling via Local Activation of Protein Phosphatase 2A
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BloodHome page
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Differential Role of Proline-Rich Tyrosine Kinase 2 and Focal Adhesion Kinase in Determining Glioblastoma Migration and Proliferation
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Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion
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