Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

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				M. P. Iwanicki, T. Vomastek, R. W. Tilghman, K. H. Martin, J. Banerjee, P. B. Wedegaertner, and J. T. Parsons FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts J. Cell Sci., March 15, 2008; 121(6): 895 - 905. [Abstract] [Full Text] [PDF]

				M. Kabir-Salmani, M. N. Fukuda, M. Kanai-Azuma, N. Ahmed, S. Shiokawa, Y. Akimoto, K. Sakai, S. Nagamori, Y. Kanai, K. Sugihara, et al. The Membrane-Spanning Domain of CD98 Heavy Chain Promotes {alpha}v{beta}3 Integrin Signals in Human Extravillous Trophoblasts Mol. Endocrinol., March 1, 2008; 22(3): 707 - 715. [Abstract] [Full Text] [PDF]

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				B. K. Wacker, S. K. Alford, E. A. Scott, M. Das Thakur, G. D. Longmore, and D. L. Elbert Endothelial Cell Migration on RGD-Peptide-Containing PEG Hydrogels in the Presence of Sphingosine 1-Phosphate Biophys. J., January 1, 2008; 94(1): 273 - 285. [Abstract] [Full Text] [PDF]

				K. Tabu, Y. Ohba, T. Suzuki, Y. Makino, T. Kimura, A. Ohnishi, M. Sakai, T. Watanabe, S. Tanaka, and H. Sawa Oligodendrocyte Lineage Transcription Factor 2 Inhibits the Motility of a Human Glial Tumor Cell Line by Activating RhoA Mol. Cancer Res., October 1, 2007; 5(10): 1099 - 1109. [Abstract] [Full Text] [PDF]

				L. P. Desai, S. E. Sinclair, K. E. Chapman, A. Hassid, and C. M. Waters High tidal volume mechanical ventilation with hyperoxia alters alveolar type II cell adhesion Am J Physiol Lung Cell Mol Physiol, September 1, 2007; 293(3): L769 - L778. [Abstract] [Full Text] [PDF]

				W. F. Liu, C. M. Nelson, J. L. Tan, and C. S. Chen Cadherins, RhoA, and Rac1 Are Differentially Required for Stretch-Mediated Proliferation in Endothelial Versus Smooth Muscle Cells Circ. Res., August 31, 2007; 101(5): e44 - e52. [Abstract] [Full Text] [PDF]

				A. Grande-Garcia, A. Echarri, J. de Rooij, N. B. Alderson, C. M. Waterman-Storer, J. M. Valdivielso, and M. A. del Pozo Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases J. Cell Biol., May 21, 2007; 177(4): 683 - 694. [Abstract] [Full Text] [PDF]

				L. Jin, M. J. Kern, C. A. Otey, B. R. Wamhoff, and A. V. Somlyo Angiotensin II, Focal Adhesion Kinase, and PRX1 Enhance Smooth Muscle Expression of Lipoma Preferred Partner and its Newly Identified Binding Partner Palladin to Promote Cell Migration Circ. Res., March 30, 2007; 100(6): 817 - 825. [Abstract] [Full Text] [PDF]

				M. Schober, S. Raghavan, M. Nikolova, L. Polak, H. A. Pasolli, H. E. Beggs, L. F. Reichardt, and E. Fuchs Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics J. Cell Biol., February 26, 2007; 176(5): 667 - 680. [Abstract] [Full Text] [PDF]

				A. Mammoto, S. Huang, and D. E. Ingber Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts J. Cell Sci., February 1, 2007; 120(3): 456 - 467. [Abstract] [Full Text] [PDF]

				R. Zaidel-Bar, R. Milo, Z. Kam, and B. Geiger A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions J. Cell Sci., January 1, 2007; 120(1): 137 - 148. [Abstract] [Full Text] [PDF]

				F. Chang, C. A. Lemmon, D. Park, and L. H. Romer FAK Potentiates Rac1 Activation and Localization to Matrix Adhesion Sites: A Role for betaPIX Mol. Biol. Cell, January 1, 2007; 18(1): 253 - 264. [Abstract] [Full Text] [PDF]

				K. Szczur, H. Xu, S. Atkinson, Y. Zheng, and M.-D. Filippi Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils Blood, December 15, 2006; 108(13): 4205 - 4213. [Abstract] [Full Text] [PDF]

				D. M. Pirone, W. F. Liu, S. A. Ruiz, L. Gao, S. Raghavan, C. A. Lemmon, L. H. Romer, and C. S. Chen An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling J. Cell Biol., July 17, 2006; 174(2): 277 - 288. [Abstract] [Full Text] [PDF]

				D. M. Cohen, B. Kutscher, H. Chen, D. B. Murphy, and S. W. Craig A Conformational Switch in Vinculin Drives Formation and Dynamics of a Talin-Vinculin Complex at Focal Adhesions J. Biol. Chem., June 9, 2006; 281(23): 16006 - 16015. [Abstract] [Full Text] [PDF]

				Z. Li, C. Wang, X. Jiao, Y. Lu, M. Fu, A. A. Quong, C. Dye, J. Yang, M. Dai, X. Ju, et al. Cyclin D1 Regulates Cellular Migration through the Inhibition of Thrombospondin 1 and ROCK Signaling. Mol. Cell. Biol., June 1, 2006; 26(11): 4240 - 4256. [Abstract] [Full Text] [PDF]

				P. M.F. Siesser and S. K. Hanks The Signaling and Biological Implications of FAK Overexpression in Cancer. Clin. Cancer Res., June 1, 2006; 12(11): 3233 - 3237. [Full Text] [PDF]

				A. Nayal, D. J. Webb, C. M. Brown, E. M. Schaefer, M. Vicente-Manzanares, and A. R. Horwitz Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics J. Cell Biol., May 22, 2006; 173(4): 587 - 589. [Abstract] [Full Text] [PDF]

				L. H. Romer, K. G. Birukov, and J. G.N. Garcia Focal Adhesions: Paradigm for a Signaling Nexus Circ. Res., March 17, 2006; 98(5): 606 - 616. [Abstract] [Full Text] [PDF]

				D. Dadke, M. Jarnik, E. N. Pugacheva, M. K. Singh, and E. A. Golemis Deregulation of HEF1 Impairs M-Phase Progression by Disrupting the RhoA Activation Cycle Mol. Biol. Cell, March 1, 2006; 17(3): 1204 - 1217. [Abstract] [Full Text] [PDF]

				I. Gorenne, L. Jin, T. Yoshida, J.M. Sanders, I.J. Sarembock, G.K. Owens, A.P. Somlyo, and A.V. Somlyo LPP Expression During In Vitro Smooth Muscle Differentiation and Stent-Induced Vascular Injury Circ. Res., February 17, 2006; 98(3): 378 - 385. [Abstract] [Full Text] [PDF]

				E. Tzima Role of Small GTPases in Endothelial Cytoskeletal Dynamics and the Shear Stress Response Circ. Res., February 3, 2006; 98(2): 176 - 185. [Abstract] [Full Text] [PDF]

				M. Holinstat, N. Knezevic, M. Broman, A. M. Samarel, A. B. Malik, and D. Mehta Suppression of RhoA Activity by Focal Adhesion Kinase-induced Activation of p190RhoGAP: ROLE IN REGULATION OF ENDOTHELIAL PERMEABILITY J. Biol. Chem., January 27, 2006; 281(4): 2296 - 2305. [Abstract] [Full Text] [PDF]

				D. Barberis, A. Casazza, R. Sordella, S. Corso, S. Artigiani, J. Settleman, P. M. Comoglio, and L. Tamagnone p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling J. Cell Sci., October 15, 2005; 118(20): 4689 - 4700. [Abstract] [Full Text] [PDF]

				R. Wang, R. A. F. Clark, D. F. Mosher, and X.-D. Ren Fibronectin's Central Cell-binding Domain Supports Focal Adhesion Formation and Rho Signal Transduction J. Biol. Chem., August 5, 2005; 280(31): 28803 - 28810. [Abstract] [Full Text] [PDF]

				E. T. Barfod, A. L. Moore, R. F. Melnick, and S. D. Lidofsky Src Regulates Distinct Pathways for Cell Volume Control through Vav and Phospholipase C{gamma} J. Biol. Chem., July 8, 2005; 280(27): 25548 - 25557. [Abstract] [Full Text] [PDF]

				A. Pullikuth, E. McKinnon, H.-J. Schaeffer, and A. D. Catling The MEK1 Scaffolding Protein MP1 Regulates Cell Spreading by Integrating PAK1 and Rho Signals Mol. Cell. Biol., June 15, 2005; 25(12): 5119 - 5133. [Abstract] [Full Text] [PDF]

				R. W. Tilghman, J. K. Slack-Davis, N. Sergina, K. H. Martin, M. Iwanicki, E. D. Hershey, H. E. Beggs, L. F. Reichardt, and J. T. Parsons Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells J. Cell Sci., June 15, 2005; 118(12): 2613 - 2623. [Abstract] [Full Text] [PDF]