The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Chen, J.
	Articles by Hirokawa, N.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Chen, J.
	Articles by Hirokawa, N.


Social Bookmarking

	What's this?

Aizawa, H., Sekine, Y., Takemura, R., Zhang, Z., Nangaku, M. andHirokawa, N (1992). Kinesin family in murine central nervous system. J. Cell Biol 119, 1287-1296.[Abstract/Free Full Text]

Balin, J. B., Clark, E. A., Trojanowski, J. Q. and Lee, V. M.-Y (1991). Neurofilament reassembly in vitro: biochemical, morphological and immuno-electron microscopic studies employing monoclonal antibodies to defined epitopes. Brain Res 556, 181-195.[Medline]

Chin, S. S. M. and Liem, R. K. H (1989). Expression of rat neurofilament proteins NF-L and NF-M in transfected non-neuronal cells. Eur. J. Cell Biol 50, 475-490.[Medline]

Chin, S. S. M. and Liem, R. K. H (1990). Transfected rat high-molecularweight neurofilament (NF-H) coassembles with vimentin in a predominantly nonphosphorylated form. J. Neurosci 10, 3714-3726.[Abstract]

Ching, G. Y. and Liem, R. K. H (1993). Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments. J. Cell Biol 122, 1323-1335.[Abstract/Free Full Text]

de Waegh, S. M., Lee, V. M.-Y. and Brady, S. T (1992). Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell 68, 451-463.[Medline]

Elder, G. A., Friendrich, V. L. Jr., Bosco, P., Kang, C., Gourov, A., Tu, P-H., Lee, V. M.-Y. and Lazzarini, R. A (1998). Absence of the mid-sized neurofilament subunit decreases axonal calibers, levels of light neurofilament (NF-L), and neurofilament content. J. Cell Biol 141, 727-739.[Abstract/Free Full Text]

Elder, G. A., Friedrich, V. L., Kang, Jr., C., Bosco, P., Gourov, A., P-H. Zhang, Tu, B., Lee, V. M.-Y. and Lazzarini, R. A (1998). Requirement of heavy neurofilament subunit in the development of axons with large calibers. J. Cell Biol 143, 195-205.[Abstract/Free Full Text]

Eyer, J. and Peterson, A (1994). Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein. Neuron 12, 389-405.[Medline]

Friede, R. L. and Samorajski, T (1970). Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice. Anat. Rec 167, 379-388.[Medline]

Geisler, N. and Weber. K (1981). Self-assembly in vitro of the 68000 molecular weight component of the mammalian neurofilament triplet proteins into intermediate sized filaments. J. Mol. Biol 151, 565-571.[Medline]

Glicksman, M. A., Soppert, D. and Willard, M. B (1987). Posttranslational modification of neurofilament polypeptides in rabbit retina. J. Neurobiol 18, 167-196.[Medline]

Guidato, S., Tsai, L. H., Woodgett, J. and Miller, C. C (1996). Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5. J. Neurochem 66, 1698-1706.[Medline]

Hirokawa, N (1982). Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method. J. Cell Biol 94, 129-142.[Abstract/Free Full Text]

Hirokawa, N., Glicksman, M. A. and Willard, M. B (1984). Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton. J. Cell Biol 98, 1523-1536.[Abstract/Free Full Text]

Hirokawa, N. and Takeda, S (1998). Gene targeting studies begin to reveal the function of neurofilament proteins. J. Cell Biol 143, 1-4.[Free Full Text]

Hisanaga, S. and Hirokawa, N (1988). Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing. J. Mol. Biol 202, 297-305.[Medline]

Hisanaga, S., Yasugawa, S., Yamakawa, T., Miyamoto, E., Ikebe, M., Uchiyama, M. and Kishimoto, T (1993). Dephosphorylation of microtubule-binding sites at the neurofilament-H tail domain by alkaline, acid, and protein phosphatases. J. Biochem 113, 705-709.

Hoffman, P. N., Cleveland, D. W., Griffin, J. W., Landes, P. W., Cowan,N. J. and Price, D. L (1987). Neurofilament gene expression: a major determinant of axonal caliber. Proc. Natl. Acad. Sci. USA 84, 3472-3476.[Abstract/Free Full Text]

Lee, M. K. and Cleveland, D. W (1994). Neurofilaments function and dysfunction: involvement in axonal growth and neuronal disease. Curr. Opin. Cell Biol 6, 34-40.[Medline]

Lee, M. K. and Cleveland, D. W (1996). Neuronal intermediate filaments. Annu. Rev. Neurosci 19, 187-217.[Medline]

Lee, V. M. Y., Otvos, L. Carden, Jr., M. J., Hollosi, M., Dietzschold, B. and Lazzarini, R.A (1988). Identification of the major multiphosphorylation site in mammalian neurofilaments. Proc. Natl. Acad. Sci. USA 85, 1998-2002.[Abstract/Free Full Text]

Lee, M. K., Xu, Z., Wong, P. C. and Cleveland, D. W (1993). Neurofilaments are obligate heteropolymers in vivo. J. Cell Biol 122, 1337-1350.[Abstract/Free Full Text]

Levy, E., Liem, R. K. H., D'Eustachio, P. and Cowan, N. J (1987). Structure and revolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. Eur. J. Biochem 166, 71-77.[Medline]

Lew, J., Winkfein, R. J., Paudel, H. K. and Wang, J. H (1992). Brain proline-directed protein kinase is a neurofilament kinase which displays high sequence homology to p34cdc2. J. Biol. Chem 267, 25922-25926.[Abstract/Free Full Text]

Lewis, S.A. and Cowan, N. J (1986). Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum. Mol. Cell. Biol 6, 1529-1534.[Abstract/Free Full Text]

Liem, R. K. and Hutchison, S. B (1982). Purification of individual components of the neurofilament triplet: filament assembly from the 70 000-dalton subunit. Biochemistry 21, 3221-3226.[Medline]

Monterio, M. J. and Cleveland, D. W (1989). Expression of NF-L and MF-M in fibroblasts reveals coassembly of neurofilament and vimentin subunits. J. Cell Biol 108, 579-593.[Abstract/Free Full Text]

Monterio, M. J., Hoffman, P. N., Gearhart, J. D. and Cleveland, D. W (1990). Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axon without affecting caliber. J. Cell Biol 111, 1543-1557.[Abstract/Free Full Text]

Mulligan, L., Balin, B. J., Lee, V. M.-Y. and Ip, W (1991). Antibody labelling of bovine neurofilament: implications on the structure of neurofilament sidearms. J. Struct. Biol 106, 1445-1460.

Myers, M. W., Lazzarini, R. A., Schlalpfer, V. M. and Nelson, D. L (1987). The human mid-sized neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. EMBO J 6, 1617-1626.[Medline]

Nakagawa, T., Chen, J., Zhang, Z., Kanai, Y. and Hirokawa, N (1995). Two distinc functions of the carboxyl-terminal tail domain of NF-M upon neurofilament assembly: Cross-bridge formation and longitudinal elongation of filaments. J. Cell Biol 129, 411-429.[Abstract/Free Full Text]

Nixon, R. A., Paskevich, P .A., Sihag, R. K. and Thayer, C. Y (1994). Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber. J. Cell Biol 126, 1031-1046.[Abstract/Free Full Text]

Ohara, O., Gahara, Y., Miyake, T., Teraoka, H. and Itamura, T. K (1993). Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene. J. Cell Biol 121, 387-395.[Abstract/Free Full Text]

Rao, M. V., Houseweart, M. K., Williamson, T. L. Crawford, T. O., Folmer, J. and Cleveland, D. W (1998). Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments do not require the neurofilament heavy subunit (NF-H) or its phosphorylation. J. Cell Biol 143, 171-181.[Abstract/Free Full Text]

Steinert, P. M. and Roop, D. R (1988). Molecular and cellular biology of intermediate filaments. Annu. Rev. Biochem 57, 593-625.[Medline]

Sun, D., Leung, C. L. and Lirm, R. K. H (1996). Phosphorylation of the high molecular weight neurofilament protein (NF-H) by cdk5 and p35. J. Biol. Chem 271, 14245-14251.[Abstract/Free Full Text]

Veeranna, K., Shetty, T., Link, W. T., Jaffe, H., Wang, J. and Pant, H. C (1995). Neuronal cyclin-dependent kinase-5 phosphorylation sites in neurofilament protein (NF-H) are dephosphorylated by protein phosphatase 2A. J. Neurochem 64, 2681-2690.[Medline]

Veeranna, K., Shetty, T., Amin, N., Grant, P., Albers, R. W. and Pant, H. C (1996). Inhibition of neuronal cyclin-dependent kinase-5 by staurosporine and purine analogs is independent of activation by Munc-18. Neurochem. Res 21, 629-636.[Medline]

Wong, P. C., Marszalek, J., Crowford, T. O., Xu, Z., Hsieh, S.-T., Griffin, J. W. and Cleveland, D. W (1995). Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons. J. Cell Biol 130, 1413-1422.[Abstract/Free Full Text]

Xu, Z.-S., Cork, L., Griffin, J. W. and Cleveland, D. W (1993). Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73, 23-33.[Medline]

Yamasaki, H., Itakura, C. and Mizutani, M (1991). Hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the Japanese quail. Acta Neuropathol 82, 427-434.[Medline]

Zhu, Q., Couillard-Despres, S. and Julien, J.-P (1997). Delayed maturation of regeneration myelinated axons in mice lacking neurofilaments. Exp. Neurol 148, 299-316.[Medline]

Zhu, Q., Lindenbaum, M., Levavasseur, F., Jacomy, H. and Julien, J.-P (1998). Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile. J. Cell Biol 143, 183-193.[Abstract/Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

M. L. Garcia, M. V. Rao, J. Fujimoto, V. B. Garcia, S. B. Shah, J. Crum, T. Gotow, Y. Uchiyama, M. Ellisman, N. A. Calcutt, et al.
Phosphorylation of Highly Conserved Neurofilament Medium KSP Repeats Is Not Required for Myelin-Dependent Radial Axonal Growth
J. Neurosci., February 4, 2009; 29(5): 1277 - 1284.
[Abstract] [Full Text] [PDF]

B. T. Helfand, L. Chang, and R. D. Goldman
Intermediate filaments are dynamic and motile elements of cellular architecture
J. Cell Sci., January 15, 2004; 117(2): 133 - 141.
[Abstract] [Full Text] [PDF]

M. L. Garcia, C. S. Lobsiger, S. B. Shah, T. J. Deerinck, J. Crum, D. Young, C. M. Ward, T. O. Crawford, T. Gotow, Y. Uchiyama, et al.
NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth
J. Cell Biol., December 8, 2003; 163(5): 1011 - 1020.
[Abstract] [Full Text] [PDF]

M. V. Rao, J. Campbell, A. Yuan, A. Kumar, T. Gotow, Y. Uchiyama, and R. A. Nixon
The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate
J. Cell Biol., December 8, 2003; 163(5): 1021 - 1031.
[Abstract] [Full Text] [PDF]

B. T. Helfand, P. Loomis, M. Yoon, and R. D. Goldman
Rapid transport of neural intermediate filament protein
J. Cell Sci., June 1, 2003; 116(11): 2345 - 2359.
[Abstract] [Full Text] [PDF]

J. Brownlees, S. Ackerley, A. J. Grierson, N. J.O. Jacobsen, K. Shea, B. H. Anderton, P. N. Leigh, C. E. Shaw, and C. C.J. Miller
Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
Hum. Mol. Genet., November 1, 2002; 11(23): 2837 - 2844.
[Abstract] [Full Text] [PDF]

M. V. Rao, M. L. Garcia, Y. Miyazaki, T. Gotow, A. Yuan, S. Mattina, C. M. Ward, N. A. Calcutt, Y. Uchiyama, R. A. Nixon, et al.
Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport
J. Cell Biol., August 19, 2002; 158(4): 681 - 693.
[Abstract] [Full Text] [PDF]

D. I. Svergun, G. Zaccai, M. Malfois, R. H. Wade, M. H. J. Koch, and F. Kozielski
Conformation of the Drosophila Motor Protein Non-claret Disjunctional in Solution from X-ray and Neutron Scattering
J. Biol. Chem., June 29, 2001; 276(27): 24826 - 24832.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Chen, J.

Articles by Hirokawa, N.

Search for Related Content

PubMed

PubMed Citation

Articles by Chen, J.

Articles by Hirokawa, N.

Social Bookmarking

What's this?

				B. T. Helfand, L. Chang, and R. D. Goldman Intermediate filaments are dynamic and motile elements of cellular architecture J. Cell Sci., January 15, 2004; 117(2): 133 - 141. [Abstract] [Full Text] [PDF]

				M. L. Garcia, C. S. Lobsiger, S. B. Shah, T. J. Deerinck, J. Crum, D. Young, C. M. Ward, T. O. Crawford, T. Gotow, Y. Uchiyama, et al. NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth J. Cell Biol., December 8, 2003; 163(5): 1011 - 1020. [Abstract] [Full Text] [PDF]

				M. V. Rao, J. Campbell, A. Yuan, A. Kumar, T. Gotow, Y. Uchiyama, and R. A. Nixon The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate J. Cell Biol., December 8, 2003; 163(5): 1021 - 1031. [Abstract] [Full Text] [PDF]

				B. T. Helfand, P. Loomis, M. Yoon, and R. D. Goldman Rapid transport of neural intermediate filament protein J. Cell Sci., June 1, 2003; 116(11): 2345 - 2359. [Abstract] [Full Text] [PDF]

				J. Brownlees, S. Ackerley, A. J. Grierson, N. J.O. Jacobsen, K. Shea, B. H. Anderton, P. N. Leigh, C. E. Shaw, and C. C.J. Miller Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport Hum. Mol. Genet., November 1, 2002; 11(23): 2837 - 2844. [Abstract] [Full Text] [PDF]

				M. V. Rao, M. L. Garcia, Y. Miyazaki, T. Gotow, A. Yuan, S. Mattina, C. M. Ward, N. A. Calcutt, Y. Uchiyama, R. A. Nixon, et al. Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport J. Cell Biol., August 19, 2002; 158(4): 681 - 693. [Abstract] [Full Text] [PDF]

				D. I. Svergun, G. Zaccai, M. Malfois, R. H. Wade, M. H. J. Koch, and F. Kozielski Conformation of the Drosophila Motor Protein Non-claret Disjunctional in Solution from X-ray and Neutron Scattering J. Biol. Chem., June 29, 2001; 276(27): 24826 - 24832. [Abstract] [Full Text] [PDF]