Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Rhind, N.
	Articles by Russell, P.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Rhind, N.
	Articles by Russell, P.

Allen, J. B., Zhou, Z., Siede, W., Friedberg, E. C. and Elledge, S. J (1994). The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes Dev 8, 2401-2415.[Abstract/Free Full Text]

Baber-Furnari, B. A., Rhind, N., Boddy, M. N., Shanahan, P., Lopez-Girona, A. and Russell, P (2000). Regulation of mitotic inhibitor mik1 helps to enforce the DNA damage checkpoint. Mol. Biol. Cell 11, 1-11.[Abstract/Free Full Text]

Barbet, N. C. and Carr, A. M (1993). Fission yeast wee1 protein kinase is not required for DNA damage-dependent mitotic arrest. Nature 364, 824-827.[Medline]

Baum, B., Wuarin, J. and Nurse, P (1997). Control of S-phase periodic transcription in the fission yeast mitotic cycle. EMBO J 16, 4676-4688.[Medline]

Bell, D. W., Varley, J. M., Szydlo, T. E., Kang, D. H., Wahrer, D. C., Shannon, K. E., Lubratovich, M., Verselis, S. J., Isselbacher, K. J., Fraumeni, J. F. et al (1999). Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 286, 2528-2531.[Abstract/Free Full Text]

Bentley, N. J., Holtzman, D. A., Flaggs, G., Keegan, K. S., DeMaggio, A., Ford, J. C., Hoekstra, M. and Carr, A. M (1996). The Schizosaccharomyces pombe Rad3 checkpoint gene. EMBO J 15, 6641-6651.[Medline]

Blasina, A., de Weyer, I. V., Laus, M. C., Luyten, W. H., Parker, A. E. and McGowan, C. H (1999). A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase. Curr. Biol 9, 1-10.[Medline]

Blasina, A., Paegle, E. S. and McGowan, C. H (1997). The role of inhibitory phosphorylation of Cdc2 following DNA replication block and radiation-induced damage in human cells. Mol. Biol. Cell 8, 1013-1023.[Abstract]

Boddy, M. N., Furnari, B., Mondesert, O. and Russell, P (1998). Replication checkpoint enforced by kinases Cds1 and Chk1. Science 280, 909-912.[Abstract/Free Full Text]

Brondello, J. M., Boddy, M. N., Furnari, B. and Russell, P (1999). Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases. Mol. Cell Biol 19, 4262-42629.[Abstract/Free Full Text]

Brown, A. L., Lee, C. H., Schwarz, J. K., Mitiku, N., Piwnica-Worms, H. and Chung, J. H (1999). A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc. Natl. Acad. Sci. USA 96, 3745-3750.[Abstract/Free Full Text]

Brown, E. J. and Baltimore, D (2000). ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev 14, 397-402.[Abstract/Free Full Text]

Busby, E. C., Leistritz, D. F., Abraham, R. T., Karnitz, L. M. and Sarkaria, J. N (2000). The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. Cancer Res 60, 2108-21012.[Abstract/Free Full Text]

Charles, J. F., Jaspersen, S. L., Tinker-Kulberg, R. L., Hwang, L., Szidon, A. and Morgan, D. O (1998). The Polo-related kinase Cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae. Curr. Biol 8, 497-507.[Medline]

Chaturvedi, P., Eng, W. K., Zhu, Y., Mattern, M. R., Mishra, R., Hurle, M. R., Zhang, X., Annan, R. S., Lu, Q., Faucette, L. F. et al. ( (1999). Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 18, 4047-4054.[Medline]

Chehab, N. H., Malikzay, A., Appel, M. and Halazonetis, T. D (2000). Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 14, 278-288.[Abstract/Free Full Text]

Chen, P., Luo, C., Deng, Y., Ryan, K., Register, J., Margosiak, S., Tempczyk-Russell, A., Nguyen, B., Myers, P., Lundgren, K. et al. ( (2000). The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation. Cell 100, 681-692.[Medline]

Christensen, P. U., Bentley, N. J., Martinho, R. G., Nielsen, O. and Carr, A. M (2000). Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis. Proc. Natl. Acad. Sci. USA 97, 2579-25684.[Abstract/Free Full Text]

Clarke, D. J., Segal, M., Mondesert, G. and Reed, S. I (1999). The Pds1 anaphase inhibitor and Mec1 kinase define distinct checkpoints coupling S phase with mitosis in budding yeast. Curr. Biol 9, 365-368.[Medline]

Cohen-Fix, O. and Koshland, D (1997). The anaphase inhibitor of Saccharomyces cerevisiae Pds1 is a target of the DNA damage checkpoint pathway. Proc. Natl. Acad. Sci. USA 94, 14361-14366.[Abstract/Free Full Text]

Coleman, T. R. and Dunphy, W. G (1994). Cdc2 regulatory factors. Curr. Opin. Cell Biol 6, 877-882.[Medline]

Corellou, F., Bisgrove, S. R., Kropf, D. L., Meijer, L., Kloareg, B. and Bouget, F (2000). A S/M DNA replication checkpoint prevents nuclear and cytoplasmic events of cell division including centrosomal axis alignment and inhibits activation of cyclin-dependent kinase-like proteins in fucoid zygotes. Development 127, 1651-1660.[Abstract]

Dasika, G. K., Lin, S. C., Zhao, S., Sung, P., Tomkinson, A. and Lee, E. Y (1999). DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene 18, 7883-7899.[Medline]

Desany, B. A., Alcasabas, A. A., Bachant, J. B. and Elledge, S. J (1998). Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev 12, 2956-2970.[Abstract/Free Full Text]

Durocher, D., Henckel, J., Fersht, A. R. and Jackson, S. P (1999). The FHA domain is a modular phosphopeptide recognition motif. Mol. Cell 4, 387-394.

Elledge, S. J (1996). Cell cycle checkpoints: preventing an identity crisis. Science 274, 1664-1672.[Abstract/Free Full Text]

Fogarty, P., Campbell, S. D., Abu-Shumays, R., Phalle, B. S., Yu, K. R., Uy, G. L., Goldberg, M. L. and Sullivan, W (1997). The Drosophila grapes gene is related to checkpoint gene Chk1/rad27 and is required for late syncytial division fidelity. Curr. Biol 7, 418-426.[Medline]

Furnari, B., Blasina, A., Boddy, M. N., McGowan, C. H. and Russell, P (1999). Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1. Mol. Biol. Cell 10, 833-845.[Abstract/Free Full Text]

Furnari, B., Rhind, N. and Russell, P (1997). Cdc25 mitotic inducer targeted by Chk1 DNA damage checkpoint kinase. Science 277, 1495-1497.[Abstract/Free Full Text]

Garcia, V., Salanoubat, M., Choisne, N. and Tissier, A (2000). An ATM homologue from arabidopsis thaliana: complete genomic organisation and expression analysis. Nucl. Acids Res 28, 1692-1699.[Abstract/Free Full Text]

Gardner, R., Putnam, C. W. and Weinert, T (1999). RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast. EMBO J 18, 3173-3185.[Medline]

Graves, P. R., Yu, L., Schwarz, J. K., Gales, J., Sausville, E. A., O'Connor, P. M. and Piwnica-Worms, H (2000). The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J. Biol. Chem 275, 5600-5605.[Abstract/Free Full Text]

Guo, Z. and Dunphy, W. G (2000). Response of Xenopus cds1 in cell-free extracts to DNA templates with double-stranded ends. Mol. Biol. Cell 11, 1535-1546.[Abstract/Free Full Text]

Hari, K. L., Santerre, A., Sekelsky, J. J., McKim, K. S., Boyd, J. B. and Hawley, R. S (1995). The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell 82, 815-821.[Medline]

Hartley, K. O., Gell, D., Smith, G. C., Zhang, H., Divecha, N., Connelly, M. A., Admon, A., Lees-Miller, S. P., Anderson, C. W. and Jackson, S. P (1995). DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 82, 849-856.[Medline]

Hartwell, L. H. and Weinert, T. A (1989). Checkpoints: controls that ensure the order of cell cycle events. Science 246, 629-634.[Abstract/Free Full Text]

Hirao, A., Kong, Y. Y., Matsuoka, S., Wakeham, A., Ruland, J., Yoshida, H., Liu, D., Elledge, S. J. and Mak, T. W (2000). DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 287, 1824-1827.[Abstract/Free Full Text]

Hofmann, K. and Bucher, P (1995). The FHA domain: a putative nuclear signaling domain found in protein kinases and transcription factors. Trends Biochem. Sci 20, 347-349.[Medline]

Huang, M., Zhou, Z. and Elledge, S. J (1998). The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell 94, 595-605.[Medline]

Jackson, J. R., Gilmartin, A., Imburgia, C., Winkler, J. D., Marshall, L. A. and Roshak, A (2000). An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage. Cancer Res 60, 566-572.[Abstract/Free Full Text]

Kastan, M. B., Zhan, Q., el-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B. and Fornace, A. J., Jr (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71, 587-597.[Medline]

Kumagai, A., Guo, Z., Emami, K. H., Wang, S. X. and Dunphy, W. G (1998). The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts. J. Cell Biol 142, 1559-1569.[Abstract/Free Full Text]

Lee, J. S., Collins, K. M., Brown, A. L., Lee, C. H. and Chung, J. H (2000). hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 404, 201-204.[Medline]

Lew, D. J. and Reed, S. I (1995). A cell cycle checkpoint monitors cell morphogenesis in budding yeast. J. Cell Biol 129, 739-749.[Abstract/Free Full Text]

Li, X. and Cai, M (1997). Inactivation of the cyclin-dependent kinase Cdc28 abrogates cell cycle arrest induced by DNA damage and disassembly of mitotic spindles in Saccharomyces cerevisiae. Mol. Cell Biol 17, 2723-2734.[Abstract]

Lim, H. H., Goh, P. Y. and Surana, U (1996). Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28. Mol. Cell Biol 16, 6385-6397.[Abstract]

Lindsay, H. D., Griffiths, D. J., Edwards, R. J., Christensen, P. U., Murray, J. M., Osman, F., Walworth, N. and Carr, A. M (1998). S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev 12, 382-395.[Abstract/Free Full Text]

Liu, Q., Guntuku, S., Cui, X. S., Matsuoka, S., Cortez, D., Tamai, K., Luo, G., Carattini-Rivera, S., DeMayo, F., Bradley, A. et al. ( (2000). Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev 14, 1448-1459.[Abstract/Free Full Text]

Liu, Y., Vidanes, G., Lin, Y. C., Mori, S. and Siede, W (2000). Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest. Mol. Gen. Genet 262, 1132-1146.[Medline]

Longhese, M. P., Foiani, M., Muzi-Falconi, M., Lucchini, G. and Plevani, P (1998). DNA damage checkpoint in budding yeast. EMBO J 17, 5525-5528.[Medline]

Lopez-Girona, A., Furnari, B., Mondesert, O. and Russell, P (1999). Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein. Nature 397, 172-175.[Medline]

Mailand, N., Falck, J., Lukas, C., Syljuasen, R. G., Welcker, M., Bartek, J. and Lukas, J (2000). Rapid destruction of human Cdc25A in response to DNA damage. Science 288, 1425-1429.[Abstract/Free Full Text]

Matsuoka, S., Huang, M. and Elledge, S. J (1998). Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282, 1893-1897.[Abstract/Free Full Text]

Minshull, J., Straight, A., Rudner, A. D., Dernburg, A. F., Belmont, A. and Murray, A. W (1996). Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr. Biol 6, 1609-1620.[Medline]

Murakami, H. and Okayama, H (1995). A kinase from fission yeast responsible for blocking mitosis in S phase. Nature 374, 817-819.[Medline]

Nishijima, H., Nishitani, H., Seki, T. and Nishimoto, T (1997). A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(Cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea. J. Cell Biol 138, 1105-1116.[Abstract/Free Full Text]

O'Connell, M. J., Raleigh, J. M., Verkade, H. M. and Nurse, P (1997). Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting Cdc2 by Y15 phosphorylation. EMBO J 16, 545-154.[Medline]

Ogg, S., Gabrielli, B. and Piwnica-Worms, H (1994). Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216. J. Biol. Chem 269, 30461-30469.[Abstract/Free Full Text]

Pati, D., Keller, C., Groudine, M. and Plon, S. E (1997). Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. Mol. Cell Biol 17, 3037-3046.[Abstract]

Pellicioli, A., Lucca, C., Liberi, G., Marini, F., Lopes, M., Plevani, P., Romano, A., Di Fiore, P. P. and Foiani, M (1999). Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J 18, 6561-6572.[Medline]

Peng, C. Y., Graves, P. R., Ogg, S., Thoma, R. S., Byrnes, M. J., 3rd, Wu,Z., Stephenson, M. T. and Piwnica-Worms, H (1998). C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. Cell Growth Differ 9, 197-208.[Abstract]

Peng, C. Y., Graves, P. R., Thoma, R. S., Wu, Z., Shaw, A. S. and Piwnica-Worms, H (1997). Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277, 1501-1505.[Abstract/Free Full Text]

Price, D., Rabinovitch, S., O'Farrell, P. H. and Campbell, S. D (2000). Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis. Genetics 155, 159-166.[Abstract/Free Full Text]

Raleigh, J. M. and O'Connell, M. J (2000). The G2 DNA damage checkpoint targets both Wee1 and Cdc25. J. Cell Sci 113, 1727-1736.[Abstract]

Rhind, N., Furnari, B. and Russell, P (1997). Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes Dev 11, 504-511.[Abstract/Free Full Text]

Rhind, N. and Russell, P (1998). Mitotic DNA damage and replication checkpoints in yeast. Curr. Opin. Cell Biol 10, 749-58.[Medline]

Rhind, N. and Russell, P (1998). Tyrosine phosphorylation of Cdc2 is required for the replication checkpoint in Schizosaccharomyces pombe. Mol. Cell Biol 18, 3782-3787.[Abstract/Free Full Text]

Sanchez, Y., Bachant, J., Wang, H., Hu, F., Liu, D., Tetzlaff, M. and Elledge, S. J (1999). Control of the DNA damage checkpoint by Chk1 and rad53 protein kinases through distinct mechanisms. Science 286, 1166-1171.[Abstract/Free Full Text]

Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H. and Elledge, S. J (1997). Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277, 1497-1501.[Abstract/Free Full Text]

Santocanale, C. and Diffley, J. F (1998). A Mec1-and Rad53-dependent checkpoint controls late-firing origins of DNA replication. Nature 395, 615-618.[Medline]

Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S. et al. ( (1995). A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268, 1749-1753.[Abstract/Free Full Text]

Shieh, S. Y., Ahn, J., Tamai, K., Taya, Y. and Prives, C (2000). The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev 14, 289-300.[Abstract/Free Full Text]

Shirahige, K., Hori, Y., Shiraishi, K., Yamashita, M., Takahashi, K., Obuse, C., Tsurimoto, T. and Yoshikawa, H (1998). Regulation of DNA-replication origins during cell-cycle progression. Nature 395, 618-621.[Medline]

Sibon, O. C., Laurencon, A., Hawley, R. and Theurkauf, W. E (1999). The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition. Curr. Biol 9, 302-312.[Medline]

Sibon, O. C., Stevenson, V. A. and Theurkauf, W. E (1997). DNA-replication checkpoint control at the Drosophila midblastula transition. Nature 388, 93-97.[Medline]

Sidorova, J. M. and Breeden, L. L (1997). Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae. Genes Dev 11, 3032-3045.[Abstract/Free Full Text]

Siede, W., Friedberg, A. S., Dianova, I. and Friedberg, E. C (1994). Characterization of G1 checkpoint control in the yeast Saccharomycescerevisiae following exposure to DNA-damaging agents. Genetics 138, 271-281.[Abstract]

Su, T. T., Campbell, S. D. and O'Farrell, P. H (1999). Drosophila grapes/Chk1 mutants are defective in cyclin proteolysis and coordination of mitotic events. Curr. Biol 9, 919-922.[Medline]

Sun, Z., Hsiao, J., Fay, D. S. and Stern, D. F (1998). Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 281, 272-274.[Abstract/Free Full Text]

Takai, H., Tominaga, K., Motoyama, N., Minamishima, Y. A., Nagahama, H., Tsukiyama, T., Ikeda, K., Nakayama, K., Nakanishi, M. and Nakayama, K (2000). Aberrant cell cycle checkpoint function and early embryonic death in Chk1(/ ) mice. Genes Dev 14, 1439-1447.[Abstract/Free Full Text]

Toczyski, D. P., Galgoczy, D. J. and Hartwell, L. H (1997). CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 90, 1097-1106.[Medline]

Tominaga, K., Morisaki, H., Kaneko, Y., Fujimoto, A., Tanaka, T., Ohtsubo, M., Hirai, M., Okayama, H., Ikeda, K. and Nakanishi, M (1999). Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53. J. Biol. Chem 274, 31463-31467.[Abstract/Free Full Text]

Wahl, G. M., Linke, S. P., Paulson, T. G. and Huang, L. C (1997). Maintaining genetic stability through TP53 mediated checkpoint control. Cancer Surv 29, 183-219.[Medline]

Walworth, N., Davey, S. and Beach, D (1993). Fission yeast Chk1 protein kinase links the rad checkpoint pathway to Cdc2. Nature 363, 368-371.[Medline]

Walworth, N. C. and Bernards, R (1996). rad -dependent response of the Chk1 -encoded protein kinase at the DNA damage checkpoint. Science 271, 353-356.[Abstract]

Weinert, T (1997). A DNA damage checkpoint meets the cell cycle engine. Science 277, 1450-1451.[Free Full Text]

Weinert, T. A., Kiser, G. L. and Hartwell, L. H (1994). Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8, 652-665.[Abstract/Free Full Text]

Westphal, C. H (1997). Cell-cycle signaling: Atm displays its many talents. Curr. Biol 7, 789-792.

Wright, J. A., Keegan, K. S., Herendeen, D. R., Bentley, N. J., Carr, A. M., Hoekstra, M. F. and Concannon, P (1998). Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc. Natl. Acad. Sci. USA 95, 7445-7450.[Abstract/Free Full Text]

Yamamoto, A., Guacci, V. and Koshland, D (1996). Pds1, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J. Cell Biol 133, 99-110.[Abstract/Free Full Text]

Zakian, V. A (1995). ATM -Related Genes: What Do They Tell Us about Functions of the Human Gene?. Cell 82, 685-687.[Medline]

Zeng, Y., Forbes, K. C., Wu, Z., Moreno, S., Piwnica-Worms, H. and Enoch, T (1998). Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature 395, 507-510.[Medline]

Zeng, Y. and Piwnica-Worms, H (1999). DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding. Mol. Cell Biol 19, 7410-7419.[Abstract/Free Full Text]

Zhou, Z. and Elledge, S. J (1993). DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell 75, 1119-1127.[Medline]

This article has been cited by other articles:

R. A. M. de Bruin, T. I. Kalashnikova, A. Aslanian, J. Wohlschlegel, C. Chahwan, J. R. Yates III, P. Russell, and C. Wittenberg
DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1
PNAS, August 12, 2008; 105(32): 11230 - 11235.
[Abstract] [Full Text] [PDF]

M. Segurado and J. F.X. Diffley
Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks
Genes & Dev., July 1, 2008; 22(13): 1816 - 1827.
[Abstract] [Full Text] [PDF]

A. B. Ansbach, C. Noguchi, I. W. Klansek, M. Heidlebaugh, T. M. Nakamura, and E. Noguchi
RFCCtf18 and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion in Schizosaccharomyces pombe
Mol. Biol. Cell, February 1, 2008; 19(2): 595 - 607.
[Abstract] [Full Text] [PDF]

M. Shikata, F. Ishikawa, and J. Kanoh
Tel2 Is Required for Activation of the Mrc1-mediated Replication Checkpoint
J. Biol. Chem., February 23, 2007; 282(8): 5346 - 5355.
[Abstract] [Full Text] [PDF]

C. Noguchi and E. Noguchi
Sap1 Promotes the Association of the Replication Fork Protection Complex With Chromatin and Is Involved in the Replication Checkpoint in Schizosaccharomyces pombe
Genetics, February 1, 2007; 175(2): 553 - 566.
[Abstract] [Full Text] [PDF]

T. Shiromizu, H. Goto, Y. Tomono, J. Bartek, G. Totsukawa, A. Inoko, M. Nakanishi, F. Matsumura, and M. Inagaki
Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1).
Genes Cells, May 1, 2006; 11(5): 477 - 485.
[Abstract] [Full Text] [PDF]

S. Pebernard, J. Wohlschlegel, W. H. McDonald, J. R. Yates III, and M. N. Boddy
The nse5-nse6 dimer mediates DNA repair roles of the smc5-smc6 complex.
Mol. Cell. Biol., March 1, 2006; 26(5): 1617 - 1630.
[Abstract] [Full Text] [PDF]

Y. Lubelsky, N. Reuven, and Y. Shaul
Autorepression of Rfx1 Gene Expression: Functional Conservation from Yeast to Humans in Response to DNA Replication Arrest
Mol. Cell. Biol., December 1, 2005; 25(23): 10665 - 10673.
[Abstract] [Full Text] [PDF]

A. Purdy, L. Uyetake, M. G. Cordeiro, and T. T. Su
Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of Grapes (Drosophila Chk1)
J. Cell Sci., August 1, 2005; 118(15): 3305 - 3315.
[Abstract] [Full Text] [PDF]

H. I. de Vries, L. Uyetake, W. Lemstra, J. F. Brunsting, T. T. Su, H. H. Kampinga, and O. C. M. Sibon
Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable
J. Cell Sci., May 1, 2005; 118(9): 1833 - 1842.
[Abstract] [Full Text] [PDF]

E. Sommariva, T. K. Pellny, N. Karahan, S. Kumar, J. A. Huberman, and J. Z. Dalgaard
Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 Are Components of a Novel S-Phase Response Pathway to Alkylation Damage
Mol. Cell. Biol., April 1, 2005; 25(7): 2770 - 2784.
[Abstract] [Full Text] [PDF]

A. Bimbo, Y. Jia, S. L. Poh, R. K. M. Karuturi, N. den Elzen, X. Peng, L. Zheng, M. O'Connell, E. T. Liu, M. K. Balasubramanian, et al.
Systematic Deletion Analysis of Fission Yeast Protein Kinases
Eukaryot. Cell, April 1, 2005; 4(4): 799 - 813.
[Abstract] [Full Text] [PDF]

Y.-H. Ou, P.-H. Chung, T.-P. Sun, and S.-Y. Shieh
p53 C-Terminal Phosphorylation by CHK1 and CHK2 Participates in the Regulation of DNA-Damage-induced C-Terminal Acetylation
Mol. Biol. Cell, April 1, 2005; 16(4): 1684 - 1695.
[Abstract] [Full Text] [PDF]

G. Zachos, M. D. Rainey, and D. A. F. Gillespie
Chk1-Dependent S-M Checkpoint Delay in Vertebrate Cells Is Linked to Maintenance of Viable Replication Structures
Mol. Cell. Biol., January 15, 2005; 25(2): 563 - 574.
[Abstract] [Full Text] [PDF]

E. B. Gomez, V. T. Angeles, and S. L. Forsburg
A Screen for Schizosaccharomyces pombe Mutants Defective in Rereplication Identifies New Alleles of rad4+, cut9+ and psf2+
Genetics, January 1, 2005; 169(1): 77 - 89.
[Abstract] [Full Text] [PDF]

J. Karagiannis, A. Bimbo, S. Rajagopalan, J. Liu, and M. K. Balasubramanian
The Nuclear Kinase Lsk1p Positively Regulates the Septation Initiation Network and Promotes the Successful Completion of Cytokinesis in Response to Perturbation of the Actomyosin Ring in Schizosaccharomyces pombe
Mol. Biol. Cell, January 1, 2005; 16(1): 358 - 371.
[Abstract] [Full Text] [PDF]

H. Zhao and P. Russell
DNA Binding Domain in the Replication Checkpoint Protein Mrc1 of Schizosaccharomyces pombe
J. Biol. Chem., December 17, 2004; 279(51): 53023 - 53027.
[Abstract] [Full Text] [PDF]

T. D. McSherry and P. R. Mueller
Xenopus Cds1 Is Regulated by DNA-Dependent Protein Kinase and ATR during the Cell Cycle Checkpoint Response to Double-Stranded DNA Ends
Mol. Cell. Biol., November 15, 2004; 24(22): 9968 - 9985.
[Abstract] [Full Text] [PDF]

S. Pebernard, W. H. McDonald, Y. Pavlova, J. R. Yates III, and M. N. Boddy
Nse1, Nse2, and a Novel Subunit of the Smc5-Smc6 Complex, Nse3, Play a Crucial Role in Meiosis
Mol. Biol. Cell, November 1, 2004; 15(11): 4866 - 4876.
[Abstract] [Full Text] [PDF]

S. Caporali, S. Falcinelli, G. Starace, M. T. Russo, E. Bonmassar, J. Jiricny, and S. D'Atri
DNA Damage Induced by Temozolomide Signals to both ATM and ATR: Role of the Mismatch Repair System
Mol. Pharmacol., September 1, 2004; 66(3): 478 - 491.
[Abstract] [Full Text] [PDF]

K. Tanaka and P. Russell
Cds1 Phosphorylation by Rad3-Rad26 Kinase Is Mediated by Forkhead-associated Domain Interaction with Mrc1
J. Biol. Chem., July 30, 2004; 279(31): 32079 - 32086.
[Abstract] [Full Text] [PDF]

A. Lehmann, S. Katayama, C. Harrison, S. Dhut, K. Kitamura, N. McDonald, and T. Toda
Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint
Genes Cells, May 1, 2004; 9(5): 367 - 382.
[Abstract] [Full Text] [PDF]

D. Loegering, S. J. H. Arlander, J. Hackbarth, B. T. Vroman, P. Roos-Mattjus, K. M. Hopkins, H. B. Lieberman, L. M. Karnitz, and S. H. Kaufmann
Rad9 Protects Cells from Topoisomerase Poison-induced Cell Death
J. Biol. Chem., April 30, 2004; 279(18): 18641 - 18647.
[Abstract] [Full Text] [PDF]

Y. Katsuragi and N. Sagata
Regulation of Chk1 Kinase by Autoinhibition and ATR-mediated Phosphorylation
Mol. Biol. Cell, April 1, 2004; 15(4): 1680 - 1689.
[Abstract] [Full Text] [PDF]

R. T. Blankley and D. Lydall
A domain of Rad9 specifically required for activation of Chk1 in budding yeast
J. Cell Sci., February 1, 2004; 117(4): 601 - 608.
[Abstract] [Full Text] [PDF]

S. J. H. Arlander, A. K. Eapen, B. T. Vroman, R. J. McDonald, D. O. Toft, and L. M. Karnitz
Hsp90 Inhibition Depletes Chk1 and Sensitizes Tumor Cells to Replication Stress
J. Biol. Chem., December 26, 2003; 278(52): 52572 - 52577.
[Abstract] [Full Text] [PDF]

S. Gonzalez, C. Prives, and C. Cordon-Cardo
p73{alpha} Regulation by Chk1 in Response to DNA Damage
Mol. Cell. Biol., November 15, 2003; 23(22): 8161 - 8171.
[Abstract] [Full Text] [PDF]

T. Bondar, E. V. Mirkin, D. S. Ucker, W. E. Walden, S. M. Mirkin, and P. Raychaudhuri
Schizosaccharomyces pombe Ddb1 Is functionally Linked to the Replication Checkpoint Pathway
J. Biol. Chem., September 26, 2003; 278(39): 37006 - 37014.
[Abstract] [Full Text] [PDF]

C. Chahwan, T. M. Nakamura, S. Sivakumar, P. Russell, and N. Rhind
The Fission Yeast Rad32 (Mre11)-Rad50-Nbs1 Complex Is Required for the S-Phase DNA Damage Checkpoint
Mol. Cell. Biol., September 15, 2003; 23(18): 6564 - 6573.
[Abstract] [Full Text] [PDF]

M. N. Boddy, P. Shanahan, W. H. McDonald, A. Lopez-Girona, E. Noguchi, J. R. Yates III, and P. Russell
Replication Checkpoint Kinase Cds1 Regulates Recombinational Repair Protein Rad60
Mol. Cell. Biol., August 15, 2003; 23(16): 5939 - 5946.
[Abstract] [Full Text] [PDF]

S. Lambert, S. J. Mason, L. J. Barber, J. A. Hartley, J. A. Pearce, A. M. Carr, and P. J. McHugh
Schizosaccharomyces pombe Checkpoint Response to DNA Interstrand Cross-Links
Mol. Cell. Biol., July 1, 2003; 23(13): 4728 - 4737.
[Abstract] [Full Text] [PDF]

P. Roos-Mattjus, K. M. Hopkins, A. J. Oestreich, B. T. Vroman, K. L. Johnson, S. Naylor, H. B. Lieberman, and L. M. Karnitz
Phosphorylation of Human Rad9 Is Required for Genotoxin-activated Checkpoint Signaling
J. Biol. Chem., June 27, 2003; 278(27): 24428 - 24437.
[Abstract] [Full Text] [PDF]

Y. Ishimi, Y. Komamura-Kohno, H.-J. Kwon, K. Yamada, and M. Nakanishi
Identification of MCM4 as a Target of the DNA Replication Block Checkpoint System
J. Biol. Chem., June 27, 2003; 278(27): 24644 - 24650.
[Abstract] [Full Text] [PDF]

L. Perez-Hidalgo, S. Moreno, and P. A. San-Segundo
Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast
J. Cell Sci., January 15, 2003; 116(2): 259 - 271.
[Abstract] [Full Text] [PDF]

M. Kai and T. S.-F. Wang
Checkpoint activation regulates mutagenic translesion synthesis
Genes & Dev., January 1, 2003; 17(1): 64 - 76.
[Abstract] [Full Text] [PDF]

K. Shimada, P. Pasero, and S. M. Gasser
ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase
Genes & Dev., December 15, 2002; 16(24): 3236 - 3252.
[Abstract] [Full Text] [PDF]

P. Roos-Mattjus, B. T. Vroman, M. A. Burtelow, M. Rauen, A. K. Eapen, and L. M. Karnitz
Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) Chromatin Association Is an Early Checkpoint Signaling Event
J. Biol. Chem., November 8, 2002; 277(46): 43809 - 43812.
[Abstract] [Full Text] [PDF]

D. R. Williams and J. R. McIntosh
mcl1+, the Schizosaccharomyces pombe Homologue of CTF4, Is Important for Chromosome Replication, Cohesion, and Segregation
Eukaryot. Cell, October 1, 2002; 1(5): 758 - 773.
[Abstract] [Full Text] [PDF]

M. Peters, C. DeLuca, A. Hirao, V. Stambolic, J. Potter, L. Zhou, J. Liepa, B. Snow, S. Arya, J. Wong, et al.
Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila
PNAS, August 20, 2002; 99(17): 11305 - 11310.
[Abstract] [Full Text] [PDF]

E. A. Kohn, N. D. Ruth, M. K. Brown, M. Livingstone, and A. Eastman
Abrogation of the S Phase DNA Damage Checkpoint Results in S Phase Progression or Premature Mitosis Depending on the Concentration of 7-Hydroxystaurosporine and the Kinetics of Cdc25C Activation
J. Biol. Chem., July 12, 2002; 277(29): 26553 - 26564.
[Abstract] [Full Text] [PDF]

M. A. Marchetti, S. Kumar, E. Hartsuiker, M. Maftahi, A. M. Carr, G. A. Freyer, W. C. Burhans, and J. A. Huberman
A single unbranched S-phase DNA damage and replication fork blockage checkpoint pathway
PNAS, May 28, 2002; 99(11): 7472 - 7477.
[Abstract] [Full Text] [PDF]

T. O'Neill, L. Giarratani, P. Chen, L. Iyer, C.-H. Lee, M. Bobiak, F. Kanai, B.-B. Zhou, J. H. Chung, and G. A. Rathbun
Determination of Substrate Motifs for Human Chk1 and hCds1/Chk2 by the Oriented Peptide Library Approach
J. Biol. Chem., May 3, 2002; 277(18): 16102 - 16115.
[Abstract] [Full Text] [PDF]

S. Katayama, K. Kitamura, A. Lehmann, O. Nikaido, and T. Toda
Fission Yeast F-box Protein Pof3 Is Required for Genome Integrity and Telomere Function
Mol. Biol. Cell, January 1, 2002; 13(1): 211 - 224.
[Abstract] [Full Text] [PDF]

				M. Segurado and J. F.X. Diffley Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks Genes & Dev., July 1, 2008; 22(13): 1816 - 1827. [Abstract] [Full Text] [PDF]

				A. B. Ansbach, C. Noguchi, I. W. Klansek, M. Heidlebaugh, T. M. Nakamura, and E. Noguchi RFCCtf18 and the Swi1-Swi3 Complex Function in Separate and Redundant Pathways Required for the Stabilization of Replication Forks to Facilitate Sister Chromatid Cohesion in Schizosaccharomyces pombe Mol. Biol. Cell, February 1, 2008; 19(2): 595 - 607. [Abstract] [Full Text] [PDF]

				M. Shikata, F. Ishikawa, and J. Kanoh Tel2 Is Required for Activation of the Mrc1-mediated Replication Checkpoint J. Biol. Chem., February 23, 2007; 282(8): 5346 - 5355. [Abstract] [Full Text] [PDF]

				C. Noguchi and E. Noguchi Sap1 Promotes the Association of the Replication Fork Protection Complex With Chromatin and Is Involved in the Replication Checkpoint in Schizosaccharomyces pombe Genetics, February 1, 2007; 175(2): 553 - 566. [Abstract] [Full Text] [PDF]

				T. Shiromizu, H. Goto, Y. Tomono, J. Bartek, G. Totsukawa, A. Inoko, M. Nakanishi, F. Matsumura, and M. Inagaki Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1). Genes Cells, May 1, 2006; 11(5): 477 - 485. [Abstract] [Full Text] [PDF]

				S. Pebernard, J. Wohlschlegel, W. H. McDonald, J. R. Yates III, and M. N. Boddy The nse5-nse6 dimer mediates DNA repair roles of the smc5-smc6 complex. Mol. Cell. Biol., March 1, 2006; 26(5): 1617 - 1630. [Abstract] [Full Text] [PDF]

				Y. Lubelsky, N. Reuven, and Y. Shaul Autorepression of Rfx1 Gene Expression: Functional Conservation from Yeast to Humans in Response to DNA Replication Arrest Mol. Cell. Biol., December 1, 2005; 25(23): 10665 - 10673. [Abstract] [Full Text] [PDF]

				A. Purdy, L. Uyetake, M. G. Cordeiro, and T. T. Su Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of Grapes (Drosophila Chk1) J. Cell Sci., August 1, 2005; 118(15): 3305 - 3315. [Abstract] [Full Text] [PDF]

				H. I. de Vries, L. Uyetake, W. Lemstra, J. F. Brunsting, T. T. Su, H. H. Kampinga, and O. C. M. Sibon Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable J. Cell Sci., May 1, 2005; 118(9): 1833 - 1842. [Abstract] [Full Text] [PDF]

				E. Sommariva, T. K. Pellny, N. Karahan, S. Kumar, J. A. Huberman, and J. Z. Dalgaard Schizosaccharomyces pombe Swi1, Swi3, and Hsk1 Are Components of a Novel S-Phase Response Pathway to Alkylation Damage Mol. Cell. Biol., April 1, 2005; 25(7): 2770 - 2784. [Abstract] [Full Text] [PDF]

				A. Bimbo, Y. Jia, S. L. Poh, R. K. M. Karuturi, N. den Elzen, X. Peng, L. Zheng, M. O'Connell, E. T. Liu, M. K. Balasubramanian, et al. Systematic Deletion Analysis of Fission Yeast Protein Kinases Eukaryot. Cell, April 1, 2005; 4(4): 799 - 813. [Abstract] [Full Text] [PDF]

				Y.-H. Ou, P.-H. Chung, T.-P. Sun, and S.-Y. Shieh p53 C-Terminal Phosphorylation by CHK1 and CHK2 Participates in the Regulation of DNA-Damage-induced C-Terminal Acetylation Mol. Biol. Cell, April 1, 2005; 16(4): 1684 - 1695. [Abstract] [Full Text] [PDF]

				G. Zachos, M. D. Rainey, and D. A. F. Gillespie Chk1-Dependent S-M Checkpoint Delay in Vertebrate Cells Is Linked to Maintenance of Viable Replication Structures Mol. Cell. Biol., January 15, 2005; 25(2): 563 - 574. [Abstract] [Full Text] [PDF]

				E. B. Gomez, V. T. Angeles, and S. L. Forsburg A Screen for Schizosaccharomyces pombe Mutants Defective in Rereplication Identifies New Alleles of rad4+, cut9+ and psf2+ Genetics, January 1, 2005; 169(1): 77 - 89. [Abstract] [Full Text] [PDF]

				J. Karagiannis, A. Bimbo, S. Rajagopalan, J. Liu, and M. K. Balasubramanian The Nuclear Kinase Lsk1p Positively Regulates the Septation Initiation Network and Promotes the Successful Completion of Cytokinesis in Response to Perturbation of the Actomyosin Ring in Schizosaccharomyces pombe Mol. Biol. Cell, January 1, 2005; 16(1): 358 - 371. [Abstract] [Full Text] [PDF]

				H. Zhao and P. Russell DNA Binding Domain in the Replication Checkpoint Protein Mrc1 of Schizosaccharomyces pombe J. Biol. Chem., December 17, 2004; 279(51): 53023 - 53027. [Abstract] [Full Text] [PDF]

				T. D. McSherry and P. R. Mueller Xenopus Cds1 Is Regulated by DNA-Dependent Protein Kinase and ATR during the Cell Cycle Checkpoint Response to Double-Stranded DNA Ends Mol. Cell. Biol., November 15, 2004; 24(22): 9968 - 9985. [Abstract] [Full Text] [PDF]

				S. Pebernard, W. H. McDonald, Y. Pavlova, J. R. Yates III, and M. N. Boddy Nse1, Nse2, and a Novel Subunit of the Smc5-Smc6 Complex, Nse3, Play a Crucial Role in Meiosis Mol. Biol. Cell, November 1, 2004; 15(11): 4866 - 4876. [Abstract] [Full Text] [PDF]

				S. Caporali, S. Falcinelli, G. Starace, M. T. Russo, E. Bonmassar, J. Jiricny, and S. D'Atri DNA Damage Induced by Temozolomide Signals to both ATM and ATR: Role of the Mismatch Repair System Mol. Pharmacol., September 1, 2004; 66(3): 478 - 491. [Abstract] [Full Text] [PDF]

				K. Tanaka and P. Russell Cds1 Phosphorylation by Rad3-Rad26 Kinase Is Mediated by Forkhead-associated Domain Interaction with Mrc1 J. Biol. Chem., July 30, 2004; 279(31): 32079 - 32086. [Abstract] [Full Text] [PDF]

				A. Lehmann, S. Katayama, C. Harrison, S. Dhut, K. Kitamura, N. McDonald, and T. Toda Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint Genes Cells, May 1, 2004; 9(5): 367 - 382. [Abstract] [Full Text] [PDF]

				D. Loegering, S. J. H. Arlander, J. Hackbarth, B. T. Vroman, P. Roos-Mattjus, K. M. Hopkins, H. B. Lieberman, L. M. Karnitz, and S. H. Kaufmann Rad9 Protects Cells from Topoisomerase Poison-induced Cell Death J. Biol. Chem., April 30, 2004; 279(18): 18641 - 18647. [Abstract] [Full Text] [PDF]

				Y. Katsuragi and N. Sagata Regulation of Chk1 Kinase by Autoinhibition and ATR-mediated Phosphorylation Mol. Biol. Cell, April 1, 2004; 15(4): 1680 - 1689. [Abstract] [Full Text] [PDF]

				R. T. Blankley and D. Lydall A domain of Rad9 specifically required for activation of Chk1 in budding yeast J. Cell Sci., February 1, 2004; 117(4): 601 - 608. [Abstract] [Full Text] [PDF]

				S. J. H. Arlander, A. K. Eapen, B. T. Vroman, R. J. McDonald, D. O. Toft, and L. M. Karnitz Hsp90 Inhibition Depletes Chk1 and Sensitizes Tumor Cells to Replication Stress J. Biol. Chem., December 26, 2003; 278(52): 52572 - 52577. [Abstract] [Full Text] [PDF]

				S. Gonzalez, C. Prives, and C. Cordon-Cardo p73{alpha} Regulation by Chk1 in Response to DNA Damage Mol. Cell. Biol., November 15, 2003; 23(22): 8161 - 8171. [Abstract] [Full Text] [PDF]

				T. Bondar, E. V. Mirkin, D. S. Ucker, W. E. Walden, S. M. Mirkin, and P. Raychaudhuri Schizosaccharomyces pombe Ddb1 Is functionally Linked to the Replication Checkpoint Pathway J. Biol. Chem., September 26, 2003; 278(39): 37006 - 37014. [Abstract] [Full Text] [PDF]

				C. Chahwan, T. M. Nakamura, S. Sivakumar, P. Russell, and N. Rhind The Fission Yeast Rad32 (Mre11)-Rad50-Nbs1 Complex Is Required for the S-Phase DNA Damage Checkpoint Mol. Cell. Biol., September 15, 2003; 23(18): 6564 - 6573. [Abstract] [Full Text] [PDF]

				M. N. Boddy, P. Shanahan, W. H. McDonald, A. Lopez-Girona, E. Noguchi, J. R. Yates III, and P. Russell Replication Checkpoint Kinase Cds1 Regulates Recombinational Repair Protein Rad60 Mol. Cell. Biol., August 15, 2003; 23(16): 5939 - 5946. [Abstract] [Full Text] [PDF]

				S. Lambert, S. J. Mason, L. J. Barber, J. A. Hartley, J. A. Pearce, A. M. Carr, and P. J. McHugh Schizosaccharomyces pombe Checkpoint Response to DNA Interstrand Cross-Links Mol. Cell. Biol., July 1, 2003; 23(13): 4728 - 4737. [Abstract] [Full Text] [PDF]