Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways

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al-Alawi, N., Rose, D. W., Buckmaster, C., Ahn, N., Rapp, U., Meinkoth, J. and Feramisco, J. R (1995). Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade. Mol. Cell. Biol 15, 1162-1168.[Abstract]

Arnould, T., Kim, E., Tsiokas, L., Jochimsen, F., Gruning, W., Chang, J. D. and Walz, G (1998). The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1. J. Biol. Chem 273, 6013-6018.[Abstract/Free Full Text]

Bassa, B. V., Roh, D. D., Vaziri, N. D., Kirschenbaum, M. A. and Kamanna, V. S (1999). Effect of inhibition of cholesterol synthetic pathway on the activation of Ras and MAP kinase in mesangial cells. Biochim. Biophys. Acta 1449, 137-149.[Medline]

Bond, M., Fabunmi, R. P., Baker, A. H. and Newby, A. C (1998). Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B. FEBS Lett 435, 435-.

Brenner, D. A., O'Hara, M., Angel, P., Chojkier, M. and Karin, M (1989). Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha. Nature 337, 661-663.[Medline]

Fabunmi, R. P., Baker, A. H., Murray, E. J., Booth, R. F. and Newby, A. C (1996). Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1,-2, and-3 in rabbit aortic smooth muscle cells. Biochem. J 315, 335-342.

Ferrari, R (1999). The role of TNF in cardiovascular disease. Pharmacol. Res 40, 97-105.[Medline]

Fisher, C., Gilbertson-Beadling, S., Powers, E. A., Petzold, G., Poorman, R. and Mitchell, M. A (1994). Interstitial collagenase is required for angiogenesis in vitro. Dev. Biol 162, 499-510.[Medline]

Goebeler, M., Kilian, K., Gillitzer, R., Kunz, M., Yoshimura, T., Brocker, E. B., Rapp, U. R. and Ludwig, S (1999). The MKK6/p38 stress kinase cascade is critical for tumor necrosis factor-alpha-induced expression of monocyte-chemoattractant protein-1 in endothelial cells. Blood 93, 857-865.[Abstract/Free Full Text]

Gum, R., Lengyel, E., Juarez, J., Chen, J. H., Sato, H., Seiki, M. and Boyd, D (1996). Stimulation of 92-kDa gelatinase B promoter activity by ras is mitogen-activated protein kinase kinase 1-independent and requires multiple transcription factor binding sites including closely spaced PEA3/ets and AP-1 sequences. J. Biol. Chem 271, 10672-10680.[Abstract/Free Full Text]

Gum, R., Wang, H., Lengyel, E., Juarez, J. and Boyd, D (1997). Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase-and the extracellular signal-regulated kinase-dependent signaling cascades. Oncogene 14, 1481-1493.[Medline]

Haller, H., Rieger, M., Lindschau, C., Kuhlmann, M., Philipp, S. and Luft, F. C (1994). LDL increases (CA++)i in human endothelial cells and augments thrombin-induced cell signalling. J. Lab. Clin. Med 124, 708-714.[Medline]

Haller, H., Ziegler, W., Lindschau, C. and Luft, F. C (1996). Endothelial cell tyrosine kinase receptor and G protein-coupled receptor activation involves distinct protein kinase C isoforms. Arterioscler. Thromb. Vasc. Biol 16, 678-686.[Abstract/Free Full Text]

Hanemaaijer, R., Koolwijk, P., le Clercq, L., de Vree, W. J. and van Hinsbergh, V. W (1993). Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester. Biochem. J 296, 803-809.

Hibbs, M. S., Hasty, K. A., Seyer, J. M., Kang, A. H. and Mainardi, C. L (1985). Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase. J. Biol. Chem 260, 2493-2500.[Abstract/Free Full Text]

Introna, M. and Mantovani, A (1997). Early activation signals in endothelial cells. Stimulation by cytokines. Arterioscler. Thromb. Vasc. Biol 17, 423-428.[Abstract/Free Full Text]

Jonat, C., Rahmsdorf, H. J., Park, K. K., Cato, A. C., Gebel, S., Ponta, H. and Herrlich, P (1990). Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62, 1189-1204.[Medline]

Kitabayashi, I., Kawakami, Z., Chiu, R., Ozawa, K., Matsuoka, T., Toyoshima, S., Umesono, K., Evans, R. M., Gachelin, G. and Yokoyama, K (1992). Transcriptional regulation of the c-jun gene by retinoic acid and E1A during differentiation of F9 cells. EMBO J 11, 167-175.[Medline]

Kr\212ling, B. M., Wiederschain, D. G., Boehm, T., Rehn, M., Mulliken, J. B. and Moses, M. A (1999). The role of matrix metalloproteinase activity in the maturation of human capillary endothelial cells in vitro. J. Cell Sci 112, 1599-1609.[Abstract]

Kurogi, T., Nabeshima, K., Kataoka, H., Okada, Y. and Koono-M (1996). Stimulation of gelatinase B and tissue inhibitors of metalloproteinase (TIMP) production in co-culture of human osteosarcoma cells and human fibroblasts: gelatinase B production was stimulated via up-regulation of fibroblast growth factor (FGF) receptor. Int. J. Cancer 66, 82-90.[Medline]

Lamoreaux, W. J., Fitzgerald, M. E., Reiner, A., Hasty, K. A. and Charles, S. T (1998). Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro. Microvasc. Res 55, 29-42.[Medline]

Laufs, U. and Liao, J. K (1998). Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J. Biol. Chem 273, 24266-24271.[Abstract/Free Full Text]

Ludwig, S., Engel, K., Hoffmeyer, A., Sithanandam, G., Neufeld, B., Palm, D., Gaestel, M. and Rapp, U. R (1996). 3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Mol. Cell Biol 16, 6687-6697.[Abstract]

Mackay, A. R., Ballin, M., Pelina, M. D., Farina, A. R., Nason, A. M., Hartzler, J. L. and Thorgeirsson, U. P (1992). Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines. Inv. Metast 12, 168-184.[Medline]

MacNaul, K. L., Chartrain, N., Lark, M., Tocci, M. J. and Hutchinson, N. I (1990). Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression. J. Biol. Chem 265, 17238-17245.[Abstract/Free Full Text]

Makela, M., Salo, T. and Larjava, H (1998). MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?. Biochem. Biophys. Res. Commun 253, 325-335.[Medline]

McCawley, L. J., O'Brien, P. and Hudson, L. G (1998). Epidermal growth factor (EGF)-and scatter factor/hepatocyte growth factor (SF/HGF)-mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9. J. Cell. Physiol 176, 255-265.[Medline]

McCawley, L. J., Li, S., Wattenberg, E. V. and Hudson, L. G (1999). Sustained activation of the mitogen-activated protein kinase pathway. A mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase-9 induction and cell migration. J. Biol. Chem 274, 4347-4353.[Abstract/Free Full Text]

Modur, V., Zimmermann, G. A., Prescott, S. M. and McIntyre, T. M (1996). Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent andindependent mitogen-activated protein kinase cascades. J. Biol. Chem 271, 13094-13102.[Abstract/Free Full Text]

Montesano, R. and Orci, L (1985). Tumor-promoting phorbol esters induce angiogenesis in vitro. Cell 42, 469-477.[Medline]

Montesano, R. and Orci, L (1987). Phorbol esters induce angiogenesis in vitro from large-vessel endothelial cells. J. Cell. Physiol 130, 284-291.[Medline]

Murphy, G., Stanton, H., Cowell, S., Butler, G., Knauper, V., Atkinson, S. and Gavrilovic, J (1999). Mechanisms for pro matrix metalloproteinase activation. APMIS 107, 38-44.[Medline]

Negre-Aminou, P., van Vliet, A. K., van Erck, M., van Thiel, G. C., van Leeuwen, R. E. and Cohen, L. H (1997). Inhibition of proliferation of human smooth muscle cells by various HMG-CoA reductase inhibitors; comparison with other human cell types. Biochim. Biophys. Acta 1345, 259-268.[Medline]

Nelimarkka, L. O., Nikkari, S. T., Ravanti, L. S., Kahari, V. M. and Jarvelainen, H. T (1998). Collagenase-1, stromelysin-1 and 92 kDa gelatinase are associated with tumor necrosis factor-alpha induced morphological change of human endothelial cells in vitro. Matrix Biol 17, 293-304.[Medline]

Osborn, M. T., Berry, A., Ruberu, M. S., Ning, B., Bell, L. M. and Chambers, T. C (1999). Phorbol ester induced MDR1 expression in K562 cells occurs independently of mitogen-activated protein kinase signaling pathways. Oncogene 18, 5756-5764.[Medline]

Puyraimond, A., Weitzman, J. B., Babiole, E. and Menashi, S (1999). Examining the relationship between the gelatinolytic balance and the invasive capacity of endothelial cells. J. Cell Sci 112, 1283-1290.[Abstract]

Qian, X., Wang, T. N., Rothman, V. L., Nicosia, R. F. and Tuszynski, G. P (1997). Thrombospondin-1 modulates angiogenesis in vitro by up-regulation of matrix metalloproteinase-9 in endothelial cells. Exp. Cell Res 235, 403-412.[Medline]

Reunanen, N., Westermarck, J., Hakkinen, L., Holmstrom, T. H., Elo, I., Eriksson, J. E. and Kahari, V. M (1998). Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. J. Biol. Chem 273, 5137-5145.[Abstract/Free Full Text]

Robbins, J. R., McGuire, P. G., Wehrle-Haller, B. and Rogers, S. L (1999). Diminished matrix metalloproteinase 2 (MMP-2) in ectomesenchyme-derived tissues of the Patch mutant mouse: regulation of MMP-2 by PDGF and effects on mesenchymal cell migration. Dev. Biol 212, 255-263.[Medline]

Robinson, M. J. and Cobb, M. H (1997). Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol 9, 180-186.[Medline]

Sato, H., Kita, M. and Seiki, M (1993). v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines. Abdom. Imaging 268, 23460-23468.

Sato, H. and Seiki, M (1993). Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8, 395-405.[Medline]

Schnaper, H. W., Grant, D. S., Stetler-Stevenson, W. G., Fridman, R., D'Orazi, G., Murphy, A. N., Bird, R. E., Hoythya, M., Fuerst, T. R., French, D. L. et al. ( (1993). Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro. J. Cell. Physiol 156, 235-246.[Medline]

Schultz, H., Engel, K. and Gaestel, M (1997). PMA-induced activation of the p42/44ERK-and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype. J. Cell. Physiol 173, 310-318.[Medline]

Simon, C., Goepfert, H. and Boyd, D (1998). Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. Cancer Res 58, 1135-1139.[Abstract/Free Full Text]

Singer, C. F., Marbaix, E., Lemoine, P., Courtoy, P. J. and Eeckhout, Y (1999). Local cytokines induce differential expression of matrix metalloproteinases but not their tissue inhibitors in human endometrial fibroblasts. Eur. J. Biochem 259, 40-45.[Medline]

Smith, C. L. and Hager, G. L (1997). Transcriptional regulation of mammalian genes in vivo. J. Biol. Chem 272, 27493-27496.[Free Full Text]

Sozeri, O., Vollmer, K., Liyanage, M., Frith, D., Kour, G., Mark, G. E. and Stabel, S (1992). Activation of the c-Raf protein kinase by protein kinase C phosphorylation. Oncogene 7, 2259-2262.[Medline]

Spiegel, S., Cuvillier, O., Edsall, L. C., Kohama, T., Menzeleev, R., Olah, Z., Olivera, A., Pirianov, G., Thomas, D. M., Tu, Z. et al. ( (1998). Sphingosine-1-phosphate in cell growth and cell death. Ann. NY Acad. Sci 845, 11-18.[Abstract/Free Full Text]

Spiegel, S. and Merrill, A. H. J (1996). Sphingolipid metabolism and cell growth regulation. FASEB J 10, 1388-1397.[Abstract]

Takahashi, K., Sawasaki, Y., Hata, J., Mukai, K. and Goto, T (1990). Spontaneous transformation and immortalization of human endothelial cells. In Vitro Cell Dev. Biol 26, 265-274.[Medline]

Takeuchi, S., Kawashima, S., Rikitake, Y., Ueyama, T., Inoue, N., Hirata, K. and Yokoyama, M (2000). Cerivastatin suppresses lipopolysaccharide-induced ICAM-1 expression through inhibition of Rho GTPase in BAEC. Biochem. Biophys. Res. Commun 269, 97-102.[Medline]

Ueda, Y., Hirai, S., Osada, S., Suzuki, A., Mizuno, K. and Ohno, S (1996). Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J. Biol. Chem 271, 23512-23519.[Abstract/Free Full Text]

Vu, T. H., Shipley, J. M., Bergers, G., Berger, J. E., Helms, J. A., Hanahan, D., Shapiro, S. D., Senior, R. M. and Werb, Z (1998). MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93, 411-422.[Medline]

Xia, P. G., J. R., Rye, K.-A., Wang, L., Hii, C. S. T., Cockerill, P., Khew.Goodall, Y., Bert, A. G., Barter, P. J. and Vadas, M. A (1998). Tumor necrosis factor-induces adhesion molecule expression through the sphingosine kinase pathway. Proc. Nat. Acad. Sci.USA 95, 14196-14201.[Abstract/Free Full Text]

Zedlacher, M., Schmoll, M., Zimmermann, K., Horstkorte, O. and Nischt, R (1999). Differential regulation of the human nidogen gene promoter region by a novel cell-type-specific silencer element. Biochem. J 338, 343-350.

Zeigler, M. E., Chi, Y., Schmidt, T. and Varani, J (1999). Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes. J. Cell. Physiol 180, 271-284.[Medline]

Zou, Y., Komuro, I., Yamazaki, T., Aikawa, R., Kudoh, S., Shiojima, I., Hiroi, Y., Mizuno, T. and Yazaki, Y (1996). Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes. J. Biol. Chem 271, 33592-33597.[Abstract/Free Full Text]

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				K. E. Porter, N. A. Turner, D. J. O'Regan, and S. G. Ball Tumor necrosis factor {alpha} induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: inhibition by simvastatin Cardiovasc Res, December 1, 2004; 64(3): 507 - 515. [Abstract] [Full Text] [PDF]

				Q Qiu, M Yang, B K Tsang, and A Gruslin EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signalling pathways Reproduction, September 1, 2004; 128(3): 355 - 363. [Abstract] [Full Text] [PDF]

				W.-N. U. Chen, R. L. Woodbury, L. E. Kathmann, L. K. Opresko, R. C. Zangar, H. S. Wiley, and B. D. Thrall Induced Autocrine Signaling through the Epidermal Growth Factor Receptor Contributes to the Response of Mammary Epithelial Cells to Tumor Necrosis Factor {alpha} J. Biol. Chem., April 30, 2004; 279(18): 18488 - 18496. [Abstract] [Full Text] [PDF]

				M. Marcet-Palacios, K. Graham, C. Cass, A. D. Befus, I. Mayers, and M. W. Radomski Nitric Oxide and Cyclic GMP Increase the Expression of Matrix Metalloproteinase-9 in Vascular Smooth Muscle J. Pharmacol. Exp. Ther., October 1, 2003; 307(1): 429 - 436. [Abstract] [Full Text] [PDF]

				K. S. Song, J.-K. Seong, K. C. Chung, W.-J. Lee, C.-H. Kim, K. N. Cho, C.-D. Kang, J. S. Koo, and J.-H. Yoon Induction of MUC8 Gene Expression by Interleukin-1{beta} Is Mediated by a Sequential ERK MAPK/RSK1/CREB Cascade Pathway in Human Airway Epithelial Cells J. Biol. Chem., September 12, 2003; 278(37): 34890 - 34896. [Abstract] [Full Text] [PDF]

				R. W. Saeed, T. Peng, and C. N. Metz Ascorbic Acid Blocks the Growth Inhibitory Effect of Tumor Necrosis Factor-{alpha} on Endothelial Cells Experimental Biology and Medicine, July 1, 2003; 228(7): 855 - 865. [Abstract] [Full Text] [PDF]

				N. Chandrasekar, S. Mohanam, S. S. Lakka, D. H. Dinh, W. C. Olivero, M. Gujrati, and Jasti. S. Rao Glial Cell-induced Endothelial Morphogenesis Is Inhibited by Interfering with Extracellular Signal-regulated Kinase Signaling Clin. Cancer Res., June 1, 2003; 9(6): 2342 - 2349. [Abstract] [Full Text] [PDF]

				M. Ferletta, Y. Kikkawa, H. Yu, J. F. Talts, M. Durbeej, A. Sonnenberg, R. Timpl, K. P. Campbell, P. Ekblom, and E. Genersch Opposing Roles of Integrin {alpha}6A{beta}1 and Dystroglycan in Laminin-mediated Extracellular Signal-regulated Kinase Activation Mol. Biol. Cell, May 1, 2003; 14(5): 2088 - 2103. [Abstract] [Full Text] [PDF]

				D. L. Allen, D. H. Teitelbaum, and K. Kurachi Growth factor stimulation of matrix metalloproteinase expression and myoblast migration and invasion in vitro Am J Physiol Cell Physiol, April 1, 2003; 284(4): C805 - C815. [Abstract] [Full Text] [PDF]

				A. Siflinger-Birnboim and A. Johnson Protein kinase C modulates pulmonary endothelial permeability: a paradigm for acute lung injury Am J Physiol Lung Cell Mol Physiol, March 1, 2003; 284(3): L435 - L451. [Abstract] [Full Text] [PDF]

				J. P. Alexander and T. S. Acott Involvement of the Erk-MAP Kinase Pathway in TNF{alpha} Regulation of Trabecular Matrix Metalloproteinases and TIMPs Invest. Ophthalmol. Vis. Sci., January 1, 2003; 44(1): 164 - 169. [Abstract] [Full Text] [PDF]

				S. G. Park, Y.-S. Kang, Y. H. Ahn, S. H. Lee, K.-R. Kim, K.-W. Kim, G. Y. Koh, Y.-G. Ko, and S. Kim Dose-dependent Biphasic Activity of tRNA Synthetase-associating Factor, p43, in Angiogenesis J. Biol. Chem., November 15, 2002; 277(47): 45243 - 45248. [Abstract] [Full Text] [PDF]

				M. Werle, U. Schmal, K. Hanna, and J. Kreuzer MCP-1 induces activation of MAP-kinases ERK, JNK and p38 MAPK in human endothelial cells Cardiovasc Res, November 1, 2002; 56(2): 284 - 292. [Abstract] [Full Text] [PDF]

				C. Zaragoza, E. Soria, E. Lopez, D. Browning, M. Balbin, C. Lopez-Otin, and S. Lamas Activation of the Mitogen Activated Protein Kinase Extracellular Signal-Regulated Kinase 1 and 2 by the Nitric Oxide-cGMP-cGMP-Dependent Protein Kinase Axis Regulates the Expression of Matrix Metalloproteinase 13 in Vascular Endothelial Cells Mol. Pharmacol., October 1, 2002; 62(4): 927 - 935. [Abstract] [Full Text] [PDF]

				J.-i. Okano and A. K. Rustgi Paclitaxel Induces Prolonged Activation of the Ras/MEK/ERK Pathway Independently of Activating the Programmed Cell Death Machinery J. Biol. Chem., May 25, 2001; 276(22): 19555 - 19564. [Abstract] [Full Text] [PDF]