Endothelial cell retraction is induced by PAK2 monophosphorylation of myosin II

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				D. A. Buchner, F. Su, J. S. Yamaoka, M. Kamei, J. A. Shavit, L. K. Barthel, B. McGee, J. D. Amigo, S. Kim, A. W. Hanosh, et al. From the Cover: pak2a mutations cause cerebral hemorrhage in redhead zebrafish PNAS, August 28, 2007; 104(35): 13996 - 14001. [Abstract] [Full Text] [PDF]

				R. Stockton, J. Reutershan, D. Scott, J. Sanders, K. Ley, and M. A. Schwartz Induction of Vascular Permeability: betaPIX and GIT1 Scaffold the Activation of Extracellular Signal-regulated Kinase by PAK Mol. Biol. Cell, June 1, 2007; 18(6): 2346 - 2355. [Abstract] [Full Text] [PDF]

				D. Mehta and A. B. Malik Signaling Mechanisms Regulating Endothelial Permeability Physiol Rev, January 1, 2006; 86(1): 279 - 367. [Abstract] [Full Text] [PDF]

				S. Jeyaraj, D. Dakhlallah, S. R. Hill, and B. S. Lee HuR Stabilizes Vacuolar H+-translocating ATPase mRNA during Cellular Energy Depletion J. Biol. Chem., November 11, 2005; 280(45): 37957 - 37964. [Abstract] [Full Text] [PDF]

				B. A. Webb, R. Eves, S. W. Crawley, S. Zhou, G. P. Cote, and A. S. Mak PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner Am J Physiol Cell Physiol, October 1, 2005; 289(4): C898 - C907. [Abstract] [Full Text] [PDF]

				Y. Takahashi, L. Li, M. Kamiryo, T. Asteriou, A. Moustakas, H. Yamashita, and P. Heldin Hyaluronan Fragments Induce Endothelial Cell Differentiation in a CD44- and CXCL1/GRO1-dependent Manner J. Biol. Chem., June 24, 2005; 280(25): 24195 - 24204. [Abstract] [Full Text] [PDF]

				A. D. Doyle and J. Lee Cyclic changes in keratocyte speed and traction stress arise from Ca2+-dependent regulation of cell adhesiveness J. Cell Sci., January 15, 2005; 118(2): 369 - 379. [Abstract] [Full Text] [PDF]

				R. A. Stockton, E. Schaefer, and M. A. Schwartz p21-activated Kinase Regulates Endothelial Permeability through Modulation of Contractility J. Biol. Chem., November 5, 2004; 279(45): 46621 - 46630. [Abstract] [Full Text] [PDF]

				P. C. Chu, J. Wu, X. C. Liao, J. Pardo, H. Zhao, C. Li, M. K. Mendenhall, E. Pali, M. Shen, S. Yu, et al. A Novel Role for p21-Activated Protein Kinase 2 in T Cell Activation J. Immunol., June 15, 2004; 172(12): 7324 - 7334. [Abstract] [Full Text] [PDF]

				A. Doyle, W. Marganski, and J. Lee Calcium transients induce spatially coordinated increases in traction force during the movement of fish keratocytes J. Cell Sci., May 1, 2004; 117(11): 2203 - 2214. [Abstract] [Full Text] [PDF]

				M. L. Vitale and M. E. Carbajal Involvement of Myosin II in Dopamine-induced Reorganization of the Lactotroph Cell's Actin Cytoskeleton J. Histochem. Cytochem., April 1, 2004; 52(4): 517 - 527. [Abstract] [Full Text] [PDF]

				D. A. Emmert, J. A. Fee, Z. M. Goeckeler, J. M. Grojean, T. Wakatsuki, E. L. Elson, B. P. Herring, P. J. Gallagher, and R. B. Wysolmerski Rho-kinase-mediated Ca2+-independent contraction in rat embryo fibroblasts Am J Physiol Cell Physiol, January 1, 2004; 286(1): C8 - C21. [Abstract] [Full Text] [PDF]

				A. P. SOMLYO and A. V. SOMLYO Ca2+ Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase Physiol Rev, October 1, 2003; 83(4): 1325 - 1358. [Abstract] [Full Text] [PDF]

				L. Koivisto, K. Alavian, L. Hakkinen, S. Pelech, C. A. McCulloch, and H. Larjava Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes J. Cell Sci., September 15, 2003; 116(18): 3749 - 3760. [Abstract] [Full Text] [PDF]

				B. R. Alevriadou CAMs and Rho small GTPases: gatekeepers for leukocyte transendothelial migration. Focus on "VCAM-1-mediated Rac signaling controls endothelial cell-cell contacts and leukocyte transmigration" Am J Physiol Cell Physiol, August 1, 2003; 285(2): C250 - C252. [Full Text] [PDF]

				P. K. McFawn, L. Shen, S. G. Vincent, A. Mak, J. E. Van Eyk, and J. T. Fisher Calcium-independent contraction and sensitization of airway smooth muscle by p21-activated protein kinase Am J Physiol Lung Cell Mol Physiol, May 1, 2003; 284(5): L863 - L870. [Abstract] [Full Text] [PDF]

				S. Yamashiro, G. Totsukawa, Y. Yamakita, Y. Sasaki, P. Madaule, T. Ishizaki, S. Narumiya, and F. Matsumura Citron Kinase, a Rho-dependent Kinase, Induces Di-phosphorylation of Regulatory Light Chain of Myosin II Mol. Biol. Cell, May 1, 2003; 14(5): 1745 - 1756. [Abstract] [Full Text] [PDF]

				P. H. Ratz and A. S. Miner Length-dependent regulation of basal myosin phosphorylation and force in detrusor smooth muscle Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2003; 284(4): R1063 - R1070. [Abstract] [Full Text] [PDF]

				M. I. Garcia Arguinzonis, A. B. Galler, U. Walter, M. Reinhard, and A. Simm Increased Spreading, Rac/p21-activated Kinase (PAK) Activity, and Compromised Cell Motility in Cells Deficient in Vasodilator-stimulated Phosphoprotein (VASP) J. Biol. Chem., November 15, 2002; 277(47): 45604 - 45610. [Abstract] [Full Text] [PDF]

				C. M. Wells, A. Abo, and A. J. Ridley PAK4 is activated via PI3K in HGF-stimulated epithelial cells J. Cell Sci., October 15, 2002; 115(20): 3947 - 3956. [Abstract] [Full Text] [PDF]

				T.-L. Chew, W. A. Wolf, P. J. Gallagher, F. Matsumura, and R. L. Chisholm A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows J. Cell Biol., February 4, 2002; 156(3): 543 - 553. [Abstract] [Full Text] [PDF]

				S. M. Dudek and J. G. N. Garcia Cytoskeletal regulation of pulmonary vascular permeability J Appl Physiol, October 1, 2001; 91(4): 1487 - 1500. [Abstract] [Full Text] [PDF]

				I. U. Schraufstatter, J. Chung, and M. Burger IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways Am J Physiol Lung Cell Mol Physiol, June 1, 2001; 280(6): L1094 - L1103. [Abstract] [Full Text] [PDF]

				J. Qu, M. S. Cammarano, Q. Shi, K. C. Ha, P. de Lanerolle, and A. Minden Activated PAK4 Regulates Cell Adhesion and Anchorage-Independent Growth Mol. Cell. Biol., May 15, 2001; 21(10): 3523 - 3533. [Abstract] [Full Text]

				M. A. Sells, A. Pfaff, and J. Chernoff Temporal and Spatial Distribution of Activated Pak1 in Fibroblasts J. Cell Biol., December 27, 2000; 151(7): 1449 - 1458. [Abstract] [Full Text] [PDF]

				M Rathman, P de Lanerolle, H Ohayon, P Gounon, and P Sansonetti Myosin light chain kinase plays an essential role in S. flexneri dissemination J. Cell Sci., January 10, 2000; 113(19): 3375 - 3386. [Abstract] [PDF]

				Z. M. Goeckeler, R. A. Masaracchia, Q. Zeng, T.-L. Chew, P. Gallagher, and R. B. Wysolmerski Phosphorylation of Myosin Light Chain Kinase by p21-activated Kinase PAK2 J. Biol. Chem., June 9, 2000; 275(24): 18366 - 18374. [Abstract] [Full Text] [PDF]

				C. Chong, L. Tan, L. Lim, and E. Manser The Mechanism of PAK Activation. AUTOPHOSPHORYLATION EVENTS IN BOTH REGULATORY AND KINASE DOMAINS CONTROL ACTIVITY J. Biol. Chem., May 11, 2001; 276(20): 17347 - 17353. [Abstract] [Full Text] [PDF]

				N. Gnesutta, J. Qu, and A. Minden The Serine/Threonine Kinase PAK4 Prevents Caspase Activation and Protects Cells from Apoptosis J. Biol. Chem., April 20, 2001; 276(17): 14414 - 14419. [Abstract] [Full Text] [PDF]

				C. Dan, A. Kelly, O. Bernard, and A. Minden Cytoskeletal Changes Regulated by the PAK4 Serine/Threonine Kinase Are Mediated by LIM Kinase 1 and Cofilin J. Biol. Chem., August 17, 2001; 276(34): 32115 - 32121. [Abstract] [Full Text] [PDF]