4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death

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				A. T. Jacobs and L. J. Marnett HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins J. Biol. Chem., April 3, 2009; 284(14): 9176 - 9183. [Abstract] [Full Text] [PDF]

				S. Nakamura, M. Shibuya, H. Nakashima, R. Hisamura, N. Masuda, T. Imagawa, M. Uehara, and K. Tsubota Involvement of Oxidative Stress on Corneal Epithelial Alterations in a Blink-Suppressed Dry Eye Invest. Ophthalmol. Vis. Sci., April 1, 2007; 48(4): 1552 - 1558. [Abstract] [Full Text] [PDF]

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				I. Rahman and I. M. Adcock Oxidative stress and redox regulation of lung inflammation in COPD. Eur. Respir. J., July 1, 2006; 28(1): 219 - 242. [Abstract] [Full Text] [PDF]

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				J. D. West, C. Ji, and L. J. Marnett Modulation of DNA Fragmentation Factor 40 Nuclease Activity by Poly(ADP-ribose) Polymerase-1 J. Biol. Chem., April 15, 2005; 280(15): 15141 - 15147. [Abstract] [Full Text] [PDF]

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				T. Ikeda, M. Sporn, T. Honda, G. W. Gribble, and D. Kufe The Novel Triterpenoid CDDO and its Derivatives Induce Apoptosis by Disruption of Intracellular Redox Balance Cancer Res., September 1, 2003; 63(17): 5551 - 5558. [Abstract] [Full Text] [PDF]

				A. Chauhan, J. Turchan, C. Pocernich, A. Bruce-Keller, S. Roth, D. A. Butterfield, E. O. Major, and A. Nath Intracellular Human Immunodeficiency Virus Tat Expression in Astrocytes Promotes Astrocyte Survival but Induces Potent Neurotoxicity at Distant Sites via Axonal Transport J. Biol. Chem., April 4, 2003; 278(15): 13512 - 13519. [Abstract] [Full Text] [PDF]

				T. MIYATA, K. KUROKAWA, and C. VAN YPERSELE DE STRIHOU Advanced Glycation and Lipoxidation End Products: Role of Reactive Carbonyl Compounds Generated during Carbohydrate and Lipid Metabolism J. Am. Soc. Nephrol., September 1, 2000; 11(9): 1744 - 1752. [Full Text]

				Y. Yang, J.-Z. Cheng, S. S. Singhal, M. Saini, U. Pandya, S. Awasthi, and Y. C. Awasthi Role of Glutathione S-Transferases in Protection against Lipid Peroxidation. OVEREXPRESSION OF hGSTA2-2 IN K562 CELLS PROTECTS AGAINST HYDROGEN PEROXIDE-INDUCED APOPTOSIS AND INHIBITS JNK AND CASPASE 3 ACTIVATION J. Biol. Chem., May 25, 2001; 276(22): 19220 - 19230. [Abstract] [Full Text] [PDF]

				C. Ji, K. R. Kozak, and L. J. Marnett Ikappa B Kinase, a Molecular Target for Inhibition by 4-Hydroxy-2-nonenal J. Biol. Chem., May 18, 2001; 276(21): 18223 - 18228. [Abstract] [Full Text] [PDF]

				J.-Z. Cheng, R. Sharma, Y. Yang, S. S. Singhal, A. Sharma, M. K. Saini, S. V. Singh, P. Zimniak, S. Awasthi, and Y. C. Awasthi Accelerated Metabolism and Exclusion of 4-Hydroxynonenal through Induction of RLIP76 and hGST5.8 Is an Early Adaptive Response of Cells to Heat and Oxidative Stress J. Biol. Chem., October 26, 2001; 276(44): 41213 - 41223. [Abstract] [Full Text] [PDF]