Expression and nuclear localization of BLM, a chromosome stability protein mutated in Bloom's syndrome, suggest a role in recombination during meiotic prophase

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Anderson, L. K., Reeves, A., Webb, L. M. and Ashley, T (1999). Distribution of crossing over on mouse synaptonemal complexes using immunofluorescent localization of MLH1 protein. Genetics 151, 1569-1579.[Abstract/Free Full Text]

Baker, S. M., Plug, A. W., Prolla, T. A., Bronner, C. E., Harris, A. C., Yao, X., Christie, D.-M., Monell, C., Arnheim, N., Bradley, A., Ashley, T. and Liskay, R. M (1996). Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nature Genet 13, 336-342.[Medline]

Barlow, A. L., Benson, F. E., West, S. C. and Hulten, M. A (1997). Distribution of the Rad51 recombinase in human and mouse spermatocytes. EMBO J 16, 5207-5215.[Medline]

Barlow, C., Liyanage, M., Moens, P. B., Deng, C. X., Reid, T. and Wynshaw-Boris, A (1997). Partial rescue of the prophase I defects of ATM -deficient mice by p53 and p21 null alleles. Nature Genet 17, 462-466.[Medline]

Baumann, P., Benson, F. E. and West, S. C (1996). Human Rad51 promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell 87, 757-.[Medline]

Bennet, R. J. and West, S. C (1995). RuvC protein resolved Holliday junctions via cleavage of the continuous (non crossover) strands. Proc. Natl. Acad. Sci. USA 92, 5639-.

Bernelot-Moens, C. and Moens, P. B (1986). Recombination nodules and chiasma localization in two Orthoptera. Chromosoma 93, 220-226.

Bishop, D. K (1994). RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis. Cell 79, 1081-1092.[Medline]

Chester, N., Kuo, F., Kozak, C., O'Hara, C. D. and Leder, P (1998). Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Genes Dev 12, 3382-3393.[Abstract/Free Full Text]

Davey, S., Han, C., Ramer, S., Klassen, J., Jacobson, A., Eisenber, A., Hopkins, K., Lieberman, H. and Freyer, G (1998). Fission yeast rad12+regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene. Mol. Cell. Biol 18, 2721-2728.[Abstract/Free Full Text]

Dobson, M. J., Pearlman, R. E., Karaiskakis, A., Spyropoulos, B. and Moens, P. B (1994). Synaptonemal complex proteins, occurrence, epitope mapping and chromosome disjunction. J. Cell Sci 107, 2749-2760.[Abstract]

Dresser, M. E., Ewing, D. J., Conrad, M. N., Dominguez, A. M., Barstead, R, Jiang, H. and Kodalek, T (1997). DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the Rad51 pathway. Genetics 147, 533-544.[Abstract]

Ellis, N. A., Groden, J., Ye, T.-Z., Straughen, J., Lennon, D. J., Ciocci, S., Proytcheva, M. and German, J (1995). The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83, 655-666.[Medline]

Freire, R., Margay, J. R., Tarsounas, M., Lowndes, N. A., Moens, P. B. and Jackson, S. P (1998). Human and mouse homologs of Schizosaccharomyces pombe rad1+and Saccharomyces cerevisiae RAD17, linkage to checkpoint control and mammalian meiosis. Genes Dev 12, 2560-2573.[Abstract/Free Full Text]

Gangloff, S., McDonald, J., Bendixen, C., Arthur, L. and Rothstein, R (1994). The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog, a potential eukaryotic reverse gyrase. Mol. Cell. Biol 14, 8391-8398.[Abstract/Free Full Text]

German, J (1993). Bloom Syndrome, a Mendelian prototype of somatic mutational disease. Medicine 71, 393-406.

Gray, M., Chen, J., Kamath-Loeb, A., Blank, A., Sopher, B., Martin, G., Oshima, J. and Loeb, L (1997). The Werner syndrome protein is a DNA helicase. Nature Genet 17, 100-103.[Medline]

Haber, J. E (1998). The many interfaces of Mre11. Cell 95, 583-586.[Medline]

Kaneko, H., Inoue, R., Fukao, T., Kasahara, K., Tashita, H., Teramoto, T. and Kondo, N (1997). Two Japanese siblings with Bloom syndrome gene mutation and B-cell lymphoma. Leuk. Lymphoma 27, 539-542.[Medline]

Karow, J., Chakraverty, R. and Hickson, I. D (1997). The Bloom's syndrome gene product is a 3-5 DNA helicase. J. Biol. Chem 272, 30611-30614.[Abstract/Free Full Text]

Keeney, S., Giroux, C. and Kleckner, N (1997). Meiosis-specific DNA double-strand breaks are catalysed by Spo11, a member of a widely conserved protein family. Cell 88, 375-.[Medline]

Kowalczykowski, S. C., Dixon, D. A., Eggleston, A. K., Lauder, S. D. and Rehrauer, W. M (1994). Biochemistry of homologous recombination in Escherichia coli. Microbiol. Rev 58, 401-465.[Abstract/Free Full Text]

Moens, P. B., Chen D. J., Shen, Z., Kolas, N., Tarsounas, M., Heng, H. H. Q. and Spyropoulos, B (1997). Rad51 immunocytology in rat and mouse spermatocytes and oocytes. Chromosoma 106, 207-215.[Medline]

Moens, P. B., Tarsounas, M., Morita, T., Habu, T., Rottinghaus, S. T., Freire, R., Jackson, S. P., Barlow, C. and Wynshaw-Boris, A (1999). The association of ATR protein with mouse meiotic chromosome cores. Chromosoma 108, 95-102.[Medline]

Roeder, G. S (1997). Meiotic chromosomes, it takes two to tango. Genes Dev 11, 2600-2620.[Free Full Text]

Seki, T., Wang, W.-S., Okumura, N., Seki, M., Katada, T. and Enomoto, T (1998). cDNA cloning of mouse BLM gene, the homologue to human Bloom's syndrome gene which is highly expressed in the testis at the mRNA level. Biochim. Biophys. Acta 1398, 377-381.[Medline]

Smith, K. N. and Nicolas, A (1998). Recombination at work for meiosis. Curr. Opin. Genet. Dev 8, 200-211.[Medline]

Soriano, P., Keitges, E. A., Schorderet, D. F., Harbers, K., Gartler, S. M. and Jaenisch, R (1987). High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis. Proc. Natl. Acad. Sci. USA 84, 7218-7220.[Abstract/Free Full Text]

Stahl, F (1996). Meiotic recombination in yeast. Coronation of the double-strand break repair model. Cell 87, 985-968.

Stewart, E., Chapman, C., Al-Khodairy, F., Carr, A. and Enoch, T (1997). rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest. EMBO J 16, 2682-2692.[Medline]

Tarsounas, M., Morita, T., Pearlman, R. E. and Moens, P. B (1999). RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes. J. Cell Biol 147, 207-220.[Abstract/Free Full Text]

Thacker, J (1999). A surfeit of RAD51 -like genes?. Trends Genet 15, 166-168.[Medline]

Walpita, D., Plug, A. W., Neff, N. A., German, J. and Ashley, T (1999). Bloom's syndrome protein, BLM, colocalizes with replication protein A in meiotic prophase nuclei of mammalian spermatocytes. Proc. Natl. Acad. Sci. USA 96, 5622-.[Abstract/Free Full Text]

Watt, P., Louis, E., Borts, R. and Hickson, I (1995). Sgs1, a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81, 253-260.[Medline]

Watt, P. M., Hickson, I. D., Borts, R. H. and Louis, E. J (1996). SGS1 , a homologue of the Bloom's and Werner's Syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144, 935-945.[Abstract]

Yamagata, K., Kato, J.-I., Shimamoto, A., Goto, M., Furuichi, Y. and Ikeda, H (1998). Bloom's and Werner's syndrome genes suppress hyper recombination in yeast sgs1 mutant, Implication for genomic instability in human diseases. Proc. Natl. Acad. Sci. USA 95, 8733-8738.[Abstract/Free Full Text]

Yu, C., Oshima, J., Fu, Y.-H., Wijsman, E., Hisama, F., Alisch, R., Matthews, S., Nakura, J., Miki, T., Ouais, S., Martin, G., Mulligan, J. and Schellenberg, G (1996). Positional cloning of the Werner's syndrome gene. Science 272, 258-262.[Abstract]

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				S.-l. Ding, J.-C. Yu, S.-T. Chen, G.-C. Hsu, S.-J. Kuo, Y. H. Lin, P.-E. Wu, and C.-Y. Shen Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility Carcinogenesis, January 1, 2009; 30(1): 43 - 49. [Abstract] [Full Text] [PDF]

				M. McVey, S. L. Andersen, Y. Broze, and J. Sekelsky Multiple Functions of Drosophila BLM Helicase in Maintenance of Genome Stability Genetics, August 1, 2007; 176(4): 1979 - 1992. [Abstract] [Full Text] [PDF]

				V. W. Choi, D. M. McCarty, and R. J. Samulski Host cell DNA repair pathways in adeno-associated viral genome processing. J. Virol., November 1, 2006; 80(21): 10346 - 10356. [Abstract] [Full Text] [PDF]

				P. E. Cohen, S. E. Pollack, and J. W. Pollard Genetic Analysis of Chromosome Pairing, Recombination, and Cell Cycle Control during First Meiotic Prophase in Mammals Endocr. Rev., June 1, 2006; 27(4): 398 - 426. [Abstract] [Full Text] [PDF]

				M. Barchi, S. Mahadevaiah, M. Di Giacomo, F. Baudat, D. G. de Rooij, P. S. Burgoyne, M. Jasin, and S. Keeney Surveillance of Different Recombination Defects in Mouse Spermatocytes Yields Distinct Responses despite Elimination at an Identical Developmental Stage Mol. Cell. Biol., August 15, 2005; 25(16): 7203 - 7215. [Abstract] [Full Text] [PDF]

				E. Sanchez-Moran, G. H. Jones, F. C. H. Franklin, and J. L. Santos A Puromycin-Sensitive Aminopeptidase Is Essential for Meiosis in Arabidopsis thaliana PLANT CELL, November 1, 2004; 16(11): 2895 - 2909. [Abstract] [Full Text] [PDF]

				X. Du, J. Shen, N. Kugan, E. E. Furth, D. B. Lombard, C. Cheung, S. Pak, G. Luo, R. J. Pignolo, R. A. DePinho, et al. Telomere Shortening Exposes Functions for the Mouse Werner and Bloom Syndrome Genes Mol. Cell. Biol., October 1, 2004; 24(19): 8437 - 8446. [Abstract] [Full Text] [PDF]

				R. Jiao, C. Z. Bachrati, G. Pedrazzi, P. Kuster, M. Petkovic, J.-L. Li, D. Egli, I. D. Hickson, and I. Stagljar Physical and Functional Interaction between the Bloom's Syndrome Gene Product and the Largest Subunit of Chromatin Assembly Factor 1 Mol. Cell. Biol., June 1, 2004; 24(11): 4710 - 4719. [Abstract] [Full Text] [PDF]

				C. Wicky, A. Alpi, M. Passannante, A. Rose, A. Gartner, and F. Muller Multiple Genetic Pathways Involving the Caenorhabditis elegans Bloom's Syndrome Genes him-6, rad-51, and top-3 Are Needed To Maintain Genome Stability in the Germ Line Mol. Cell. Biol., June 1, 2004; 24(11): 5016 - 5027. [Abstract] [Full Text] [PDF]

				D. Perera, L. Perez-Hidalgo, P. B. Moens, K. Reini, N. Lakin, J. E. Syvaoja, P. A. San-Segundo, and R. Freire TopBP1 and ATR Colocalization at Meiotic Chromosomes: Role of TopBP1/Cut5 in the Meiotic Recombination Checkpoint Mol. Biol. Cell, April 1, 2004; 15(4): 1568 - 1579. [Abstract] [Full Text] [PDF]

				H. Gao, X.-B. Chen, and C. H. McGowan Mus81 Endonuclease Localizes to Nucleoli and to Regions of DNA Damage in Human S-phase Cells Mol. Biol. Cell, December 1, 2003; 14(12): 4826 - 4834. [Abstract] [Full Text] [PDF]

				Y. T. Kwon, Z. Xia, J. Y. An, T. Tasaki, I. V. Davydov, J. W. Seo, J. Sheng, Y. Xie, and A. Varshavsky Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway Mol. Cell. Biol., November 15, 2003; 23(22): 8255 - 8271. [Abstract] [Full Text] [PDF]

				P. B. Moens, N. K. Kolas, M. Tarsounas, E. Marcon, P. E. Cohen, and B. Spyropoulos The time course and chromosomal localization of recombination-related proteins at meiosis in the mouse are compatible with models that can resolve the early DNA-DNA interactions without reciprocal recombination J. Cell Sci., April 15, 2002; 115(8): 1611 - 1622. [Abstract] [Full Text] [PDF]

				L. K. Anderson, K. D. Hooker, and S. M. Stack The Distribution of Early Recombination Nodules on Zygotene Bivalents From Plants Genetics, November 1, 2001; 159(3): 1259 - 1269. [Abstract] [Full Text] [PDF]

				R. Freire, F. d'Adda di Fagagna, L. Wu, G. Pedrazzi, I. Stagljar, I. D. Hickson, and S. P. Jackson Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase III{alpha} Nucleic Acids Res., August 1, 2001; 29(15): 3172 - 3180. [Abstract] [Full Text] [PDF]

				E. M. Taylor, J. S. Moghraby, J. H. Lees, B. Smit, P. B. Moens, and A. R. Lehmann Characterization of a Novel Human SMC Heterodimer Homologous to the Schizosaccharomyces pombe Rad18/Spr18 Complex Mol. Biol. Cell, June 1, 2001; 12(6): 1583 - 1594. [Abstract] [Full Text] [PDF]

				O. Bischof, S.-H. Kim, J. Irving, S. Beresten, N. A. Ellis, and J. Campisi Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage J. Cell Biol., April 16, 2001; 153(2): 367 - 380. [Abstract] [Full Text] [PDF]

				T. Hassold, S. Sherman, and P. Hunt Counting cross-overs: characterizing meiotic recombination in mammals Hum. Mol. Genet., October 1, 2000; 9(16): 2409 - 2419. [Abstract] [Full Text] [PDF]

				L. WU, S.L. DAVIES, and I.D. HICKSON Roles of RecQ Family Helicases in the Maintenance of Genome Stability Cold Spring Harb Symp Quant Biol, January 1, 2000; 65(0): 573 - 582. [Abstract] [PDF]

				O. Bischof, S. Galande, F. Farzaneh, T. Kohwi-Shigematsu, and J. Campisi Selective Cleavage of BLM, the Bloom Syndrome Protein, during Apoptotic Cell Death J. Biol. Chem., April 6, 2001; 276(15): 12068 - 12075. [Abstract] [Full Text] [PDF]