TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Han, Y. P.
	Articles by Garner, W. L.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Han, Y. P.
	Articles by Garner, W. L.

Arumugam, S., Jang, Y. C., Chen-Jensen, C., Gibran, N. S. and Isik, F. F (1999). Temporal activity of plasminogen activators and matrix metalloproteinases during cutaneous wound repair. Surgery 125, 587-593.[Medline]

Birkedal-Hansen, H (1995). Proteolytic remodeling of extracellular matrix. Curr. Opin. Cell Biol 7, 728-735.[Medline]

Birkedal-Hansen, H., Moore, W. G., Bodden, M. K., Windsor, L. J., Birkedal-Hansen, B., DeCarlo, A. and Engler, J. A (1993). Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med 4, 197-250.[Abstract/Free Full Text]

Bullen, E. C., Longaker, M. T., Updike, D. L., Benton, R., Ladin, D., Hou, Z. and Howard, E. W (1995). Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds. J. Invest. Dermatol 104, 236-240.[Medline]

Cooney, R., Iocono, J., Maish, G., Smith, J. S. and Ehrlich, P (1997). Tumor necrosis factor mediates impaired wound healing in chronic abdominal sepsis. J. Trauma 42, 415-420.[Medline]

Ehrlich, H. P. and Rajaratnam, J. B (1990). Cell locomotion forces versus cell contraction forces for collagen lattice contraction: an in vitro model of wound contraction. Tissue Cell 22, 407-417.[Medline]

Fajardo, L. F., Kwan, H. H., Kowalski, J., Prionas, S. D. and Allison, A. C. ( (1992). Dual role of tumor necrosis factor-alpha in angiogenesis. Am. J. Pathol 140, 539-544.[Abstract]

Forsyth, P. A., Wong, H., Laing, T. D., Rewcastle, N. B., Morris, D. G., Muzik, H., Leco, K. J., Johnston, R. N., Brasher, P. M., Sutherland, G. and Edwards, D. R (1999). Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br. J. Cancer 79, 1828-1835.[Medline]

Fortunato, S. J., Menon, R. and Lombardi, S. J (1998). The effect of transforming growth factor and interleukin-10 on interleukin-8 release by human amniochorion may regulate histologic chorioamnionitis. Am. J. Obstet. Gynecol 179, 794-799.[Medline]

Garner, W. L., Karmiol, S., Rodriguez, J. L., Smith, D. J. Jr. and Phan, S. H (1993). Phenotypic differences in cytokine responsiveness of hypertrophic scar versus normal dermal fibroblasts. J. Invest. Dermatol 101, 875-879.[Medline]

Ghosh, S., May, M. J. and Kopp, E. B (1998). NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol 16, 225-260.[Medline]

Haas, T. L., Davis, S. J. and Madri, J. A (1998). Three-dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells. J. Biol. Chem 273, 3604-3610.[Abstract/Free Full Text]

Haas, T. L., Stitelman, D., Davis, S. J., Apte, S. S. and Madri, J. A (1999). Egr-1 mediates extracellular matrix-driven transcription of membrane type 1 matrix metalloproteinase in endothelium. J. Biol. Chem 274, 22679-22685.[Abstract/Free Full Text]

Kahari, V. M. and Saarialho-Kere, U (1999). Matrix metalloproteinases and their inhibitors in tumour growth and invasion. Ann. Med 31, 34-45.[Medline]

Kitzis, V., Engrav, L. H. and Quinn, L. S (1999). Transient exposure to tumor necrosis factor-alpha inhibits collagen accumulation by cultured hypertrophic scar fibroblasts. J. Surg. Res 87, 134-141.[Medline]

Leibovich, S. J., Polverini, P. J., Shepard, H. M., Wiseman, D. M., Shively, V. and Nuseir, N (1987). Macrophage-induced angiogenesis is mediated by tumour necrosis factor-alpha. Nature 329, 630-632.[Medline]

Lin, Y. Z., Yao, S. Y., Veach, R. A., Torgerson, T. R. and Hawiger, J (1995). Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem 270, 14255-14258.[Abstract/Free Full Text]

Lohi, J., Lehti, K., Valtanen, H., Parks, W. C. and Keski-Oja, J (2000). Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene. Gene 242, 75-86.[Medline]

Madtes, D. K., Raines, E. W., Sakariassen, K. S., Assoian, R. K., Sporn,M. B., Bell, G. I. and Ross, R (1988). Induction of transforming growth factor-alpha in activated human alveolar macrophages. Cell 53, 285-293.[Medline]

Martin, P (1997). Wound healing \320 aiming for perfect skin regeneration. Science 276, 75-81.[Abstract/Free Full Text]

Mercurio, F. and Manning, A. M (1999). Multiple signals converging on NF-kappaB. Curr. Opin. Cell Biol 11, 226-232.[Medline]

Migita, K., Eguchi, K., Kawabe, Y., Ichinose, Y., Tsukada, T., Aoyagi, T., Nakamura, H. and Nagataki, S (1996). TNF-alpha-mediated expression of membrane-type matrix metalloproteinase in rheumatoid synovial fibroblasts. Immunology 89, 553-557.[Medline]

Mohan, R., Rinehart, W. B., Bargagna-Mohan, P. and Fini, M. E (1998). Gelatinase B/lacZ transgenic mice, a model for mapping gelatinase B expression during developmental and injury-related tissue remodeling. J. Biol. Chem 273, 25903-25914.[Abstract/Free Full Text]

Moses, M. A., Marikovsky, M., Harper, J. W., Vogt, P., Eriksson, E., Klagsbrun, M. and Langer, R (1996). Temporal study of the activity of matrix metalloproteinases and their endogenous inhibitors during wound healing. J. Cell Biochem 60, 379-386.[Medline]

Murphy, G., Stanton, H., Cowell, S., Butler, G., Knauper, V., Atkinson, S. and Gavrilovic, J (1999). Mechanisms for pro matrix metalloproteinase activation. APMIS 107, 38-44.[Medline]

Reno, C., Boykiw, R., Martinez, M. L. and Hart, D. A (1998). Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament. Biochem. Biophys. Res. Commun 252, 757-763.[Medline]

Salomon, G. D., Kasid, A., Cromack, D. T., Director, E., Talbot, T. L., Sank, A. and Norton, J. A (1991). The local effects of cachectin/tumor necrosis factor on wound healing. Ann. Surg 214, 175-180.[Medline]

Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E. and Seiki, M (1994). A matrix metalloproteinase expressed on the surface of invasive tumour cells [see comments]. Nature 370, 61-65.[Medline]

Sunderkotter, C., Steinbrink, K., Goebeler, M., Bhardwaj, R. and Sorg, C (1994). Macrophages and angiogenesis. J. Leuko. Biol 55, 410-422.[Abstract]

Thompson, E. W., Yu, M., Bueno, J., Jin, L., Maiti, S. N., Palao-Marco, F. L., Pulyaeva, H., Tamborlane, J. W., Tirgari, R., Wapnir, I. et al. ( (1994). Collagen induced MMP-2 activation in human breast cancer. Breast Cancer Res. Treat 31, 357-370.[Medline]

Tuan, T. L., Keller, L. C., Sun, D., Nimni, M. E. and Cheung, D (1994). Dermal fibroblasts activate keratinocyte outgrowth on collagen gels. J. Cell Sci 107, 2285-2289.[Abstract]

Werb, Z. and Chin, J. R (1998). Extracellular matrix remodeling during morphogenesis. Ann. NY Acad. Sci 857, 110-118.[Abstract/Free Full Text]

Wysocki, A. B., Staiano-Coico, L. and Grinnell, F (1993). Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J. Invest. Dermatol 101, 64-68.[Medline]

Xu, J., Zutter, M. M., Santoro, S. A. and Clark, R. A (1998). A three-dimensional collagen lattice activates NF-kappaB in human fibroblasts: role in integrin alpha2 gene expression and tissue remodeling. J. Cell Biol 140, 709-719.[Abstract/Free Full Text]

Yammamoto, H., Itoh, F., Adachi, Y., Fukushima, H., Itoh, H., Sasaki, S., Hinoda, Y. and Imai, K (1999). Messenger RNA expression of matrix metalloproteinase and tissue inhibitors of metalloproteinase in human hepatocellular carcinoma. Jpn J. Clin. Oncol 29, 58-62.[Abstract/Free Full Text]

Young, P. K. and Grinnell, F (1994). Metalloproteinase activation cascade after burn injury: a longitudinal analysis of the human wound environment. J. Invest. Dermatol 103, 660-664.[Medline]

This article has been cited by other articles:

E. K. Robinson, D. P. Kelly, D. W. Mercer, and R. A. Kozar
Differential Effects of Luminal Arginine and Glutamine on Metalloproteinase Production in the Postischemic Gut
JPEN J Parenter Enteral Nutr, July 1, 2008; 32(4): 433 - 438.
[Abstract] [Full Text] [PDF]

B. Annabi, S. Rojas-Sutterlin, C. Laflamme, M.-P. Lachambre, Y. Rolland, H. Sartelet, and R. Beliveau
Tumor Environment Dictates Medulloblastoma Cancer Stem Cell Expression and Invasive Phenotype
Mol. Cancer Res., June 1, 2008; 6(6): 907 - 916.
[Abstract] [Full Text] [PDF]

N. Pottier, C. Chupin, V. Defamie, B. Cardinaud, R. Sutherland, G. Rios, F. Gauthier, P. J. Wolters, Y. Berthiaume, P. Barbry, et al.
Relationships between Early Inflammatory Response to Bleomycin and Sensitivity to Lung Fibrosis: A Role for Dipeptidyl-Peptidase I and Tissue Inhibitor of Metalloproteinase-3?
Am. J. Respir. Crit. Care Med., December 1, 2007; 176(11): 1098 - 1107.
[Abstract] [Full Text] [PDF]

Y.-P. Han, C. Yan, L. Zhou, L. Qin, and H. Tsukamoto
A Matrix Metalloproteinase-9 Activation Cascade by Hepatic Stellate Cells in Trans-differentiation in the Three-dimensional Extracellular Matrix
J. Biol. Chem., April 27, 2007; 282(17): 12928 - 12939.
[Abstract] [Full Text] [PDF]

J.-M. Park, A. Kim, J.-H. Oh, and A.-S. Chung
Methylseleninic acid inhibits PMA-stimulated pro-MMP-2 activation mediated by MT1-MMP expression and further tumor invasion through suppression of NF-{kappa}B activation
Carcinogenesis, April 1, 2007; 28(4): 837 - 847.
[Abstract] [Full Text] [PDF]

L. Connelly, C. Robinson-Benion, M. Chont, L. Saint-Jean, H. Li, V. V. Polosukhin, T. S. Blackwell, and F. E. Yull
A Transgenic Model Reveals Important Roles for the NF-{kappa}B Alternative Pathway (p100/p52) in Mammary Development and Links to Tumorigenesis
J. Biol. Chem., March 30, 2007; 282(13): 10028 - 10035.
[Abstract] [Full Text] [PDF]

Y. Onai, J.-i. Suzuki, Y. Maejima, G. Haraguchi, S. Muto, A. Itai, and M. Isobe
Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction
Am J Physiol Heart Circ Physiol, January 1, 2007; 292(1): H530 - H538.
[Abstract] [Full Text] [PDF]

R. Sharony, G. Pintucci, P. C. Saunders, E. A. Grossi, F. G. Baumann, A. C. Galloway, and P. Mignatti
Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2
Am J Physiol Heart Circ Physiol, April 1, 2006; 290(4): H1651 - H1659.
[Abstract] [Full Text] [PDF]

A. M. Manso, L. Elsherif, S.-M. Kang, and R. S. Ross
Integrins, membrane-type matrix metalloproteinases and ADAMs: Potential implications for cardiac remodeling
Cardiovasc Res, February 15, 2006; 69(3): 574 - 584.
[Abstract] [Full Text] [PDF]

Y. Ben-Yosef, A. Miller, S. Shapiro, and N. Lahat
Hypoxia of endothelial cells leads to MMP-2-dependent survival and death
Am J Physiol Cell Physiol, November 1, 2005; 289(5): C1321 - C1331.
[Abstract] [Full Text] [PDF]

P. Gerke, L. Sellin, O. Kretz, D. Petraschka, H. Zentgraf, T. Benzing, and G. Walz
NEPH2 Is Located at the Glomerular Slit Diaphragm, Interacts with Nephrin and Is Cleaved from Podocytes by Metalloproteinases
J. Am. Soc. Nephrol., June 1, 2005; 16(6): 1693 - 1702.
[Abstract] [Full Text] [PDF]

S. Saika, T. Miyamoto, O. Yamanaka, T. Kato, Y. Ohnishi, K. C. Flanders, K. Ikeda, Y. Nakajima, W. W.-Y. Kao, M. Sato, et al.
Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-{kappa}B, in Treatment of Corneal Alkali Burns in Mice
Am. J. Pathol., May 1, 2005; 166(5): 1393 - 1403.
[Abstract] [Full Text] [PDF]

A. Mazzocca, S. C. Sciammetta, V. Carloni, L. Cosmi, F. Annunziato, T. Harada, S. Abrignani, and M. Pinzani
Binding of Hepatitis C Virus Envelope Protein E2 to CD81 Up-regulates Matrix Metalloproteinase-2 in Human Hepatic Stellate Cells
J. Biol. Chem., March 25, 2005; 280(12): 11329 - 11339.
[Abstract] [Full Text] [PDF]

R. Lobmann, G. Schultz, and H. Lehnert
Proteases and the Diabetic Foot Syndrome: Mechanisms and Therapeutic Implications
Diabetes Care, February 1, 2005; 28(2): 461 - 471.
[Full Text] [PDF]

S. G. Park, H. Shin, Y. K. Shin, Y. Lee, E.-C. Choi, B.-J. Park, and S. Kim
The Novel Cytokine p43 Stimulates Dermal Fibroblast Proliferation and Wound Repair
Am. J. Pathol., February 1, 2005; 166(2): 387 - 398.
[Abstract] [Full Text] [PDF]

S. Meiners, B. Hocher, A. Weller, M. Laule, V. Stangl, C. Guenther, M. Godes, A. Mrozikiewicz, G. Baumann, and K. Stangl
Downregulation of Matrix Metalloproteinases and Collagens and Suppression of Cardiac Fibrosis by Inhibition of the Proteasome
Hypertension, October 1, 2004; 44(4): 471 - 477.
[Abstract] [Full Text] [PDF]

Z. Xie, M. Singh, and K. Singh
Differential Regulation of Matrix Metalloproteinase-2 and -9 Expression and Activity in Adult Rat Cardiac Fibroblasts in Response to Interleukin-1{beta}
J. Biol. Chem., September 17, 2004; 279(38): 39513 - 39519.
[Abstract] [Full Text] [PDF]

A. Thathiah, M. Brayman, N. Dharmaraj, J. J. Julian, E. L. Lagow, and D. D. Carson
Tumor Necrosis Factor {alpha} Stimulates MUC1 Synthesis and Ectodomain Release in a Human Uterine Epithelial Cell Line
Endocrinology, September 1, 2004; 145(9): 4192 - 4203.
[Abstract] [Full Text] [PDF]

S. Amin, N. H. V. Chong, T. A. Bailey, J. Zhang, C. Knupp, M. E. Cheetham, J. Greenwood, and P. J. Luthert
Modulation of Sub-RPE Deposits In Vitro: A Potential Model for Age-Related Macular Degeneration
Invest. Ophthalmol. Vis. Sci., May 1, 2004; 45(5): 1281 - 1288.
[Abstract] [Full Text] [PDF]

I. A. Arenas, Y. Xu, P. Lopez-Jaramillo, and S. T. Davidge
Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-{alpha}
Am J Physiol Cell Physiol, April 1, 2004; 286(4): C779 - C784.
[Abstract] [Full Text] [PDF]

H. M. Wang, X. Zhang, D. Qian, H. Y. Lin, Q. L. Li, D. L. Liu, G. Y. Liu, X. D. Yu, and C. Zhu
Effect of Ubiquitin-Proteasome Pathway on Mouse Blastocyst Implantation and Expression of Matrix Metalloproteinases-2 and -9
Biol Reprod, February 1, 2004; 70(2): 481 - 487.
[Abstract] [Full Text] [PDF]

Z. Xie, M. Singh, D. A. Siwik, W. L. Joyner, and K. Singh
Osteopontin Inhibits Interleukin-1{beta}-stimulated Increases in Matrix Metalloproteinase Activity in Adult Rat Cardiac Fibroblasts: ROLE OF PROTEIN KINASE C-{zeta}
J. Biol. Chem., December 5, 2003; 278(49): 48546 - 48552.
[Abstract] [Full Text] [PDF]

W. Gu, D. Weihrauch, K. Tanaka, J. P. Tessmer, P. S. Pagel, J. R. Kersten, W. M. Chilian, and D. C. Warltier
Reactive oxygen species are critical mediators of coronary collateral development in a canine model
Am J Physiol Heart Circ Physiol, October 1, 2003; 285(4): H1582 - H1589.
[Abstract] [Full Text] [PDF]

B.-W. Wang, H. Chang, S. Lin, P. Kuan, and K.-G. Shyu
Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-{alpha} in cultured human umbilical vein endothelial cells
Cardiovasc Res, August 1, 2003; 59(2): 460 - 469.
[Abstract] [Full Text] [PDF]

X. Liao, J. B. Thrasher, J. Pelling, J. Holzbeierlein, Q.-X. A. Sang, and B. Li
Androgen Stimulates Matrix Metalloproteinase-2 Expression in Human Prostate Cancer
Endocrinology, May 1, 2003; 144(5): 1656 - 1663.
[Abstract] [Full Text] [PDF]

M. Hirata, T. Sato, M. Tsumagari, A. Shimada, H. Nakano, K. Hashizume, and A. Ito
Differential Regulation of the Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases by Cytokines and Growth Factors in Bovine Endometrial Stromal Cells and Trophoblast Cell Line BT-1 In Vitro
Biol Reprod, April 1, 2003; 68(4): 1276 - 1281.
[Abstract] [Full Text] [PDF]

V. Poulaki, C. S. Mitsiades, A. M. Joussen, A. Lappas, B. Kirchhof, and N. Mitsiades
Constitutive Nuclear Factor-{kappa}B Activity Is Crucial for Human Retinoblastoma Cell Viability
Am. J. Pathol., December 1, 2002; 161(6): 2229 - 2240.
[Abstract] [Full Text] [PDF]

A.-M. Khatib, L. Fallavollita, E. V. Wancewicz, B. P. Monia, and P. Brodt
Inhibition of Hepatic Endothelial E-Selectin Expression by C-raf Antisense Oligonucleotides Blocks Colorectal Carcinoma Liver Metastasis
Cancer Res., October 1, 2002; 62(19): 5393 - 5398.
[Abstract] [Full Text] [PDF]

P. O. Esteve, E. Chicoine, O. Robledo, F. Aoudjit, A. Descoteaux, E. F. Potworowski, and Y. St-Pierre
Protein Kinase C-zeta Regulates Transcription of the Matrix Metalloproteinase-9 Gene Induced by IL-1 and TNF-alpha in Glioma Cells via NF-kappa B
J. Biol. Chem., September 13, 2002; 277(38): 35150 - 35155.
[Abstract] [Full Text] [PDF]

Y.-P. Han, Y.-D. Nien, and W. L. Garner
Tumor Necrosis Factor-alpha -induced Proteolytic Activation of Pro-matrix Metalloproteinase-9 by Human Skin Is Controlled by Down-regulating Tissue Inhibitor of Metalloproteinase-1 and Mediated by Tissue-associated Chymotrypsin-like Proteinase
J. Biol. Chem., July 19, 2002; 277(30): 27319 - 27327.
[Abstract] [Full Text] [PDF]

N. Mitsiades, C. S. Mitsiades, V. Poulaki, D. Chauhan, P. G. Richardson, T. Hideshima, N. Munshi, S. P. Treon, and K. C. Anderson
Biologic sequelae of nuclear factor-kappa B blockade in multiple myeloma: therapeutic applications
Blood, May 13, 2002; 99(11): 4079 - 4086.
[Abstract] [Full Text] [PDF]

R. A. Collins and M. D. Grounds
The Role of Tumor Necrosis Factor-alpha (TNF-{alpha}) in Skeletal Muscle Regeneration: Studies in TNF-{alpha}(-/-) and TNF-{alpha}(-/-)/LT-{alpha}(-/-) Mice
J. Histochem. Cytochem., August 1, 2001; 49(8): 989 - 1002.
[Abstract] [Full Text] [PDF]

G. F. Pierce
Inflammation in Nonhealing Diabetic Wounds : The Space-Time Continuum Does Matter
Am. J. Pathol., August 1, 2001; 159(2): 399 - 403.
[Full Text]

Y.-P. Han, T.-L. Tuan, M. Hughes, H. Wu, and W. L. Garner
Transforming Growth Factor-beta - and Tumor Necrosis Factor-alpha -mediated Induction and Proteolytic Activation of MMP-9 in Human Skin
J. Biol. Chem., June 15, 2001; 276(25): 22341 - 22350.
[Abstract] [Full Text] [PDF]

M. Chen, F. K. Costa, C. R. Lindvay, Y.-P. Han, and D. T. Woodley
The Recombinant Expression of Full-length Type VII Collagen and Characterization of Molecular Mechanisms Underlying Dystrophic Epidermolysis Bullosa
J. Biol. Chem., January 11, 2002; 277(3): 2118 - 2124.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Han, Y. P.

Articles by Garner, W. L.

Search for Related Content

PubMed

PubMed Citation

Articles by Han, Y. P.

Articles by Garner, W. L.

				B. Annabi, S. Rojas-Sutterlin, C. Laflamme, M.-P. Lachambre, Y. Rolland, H. Sartelet, and R. Beliveau Tumor Environment Dictates Medulloblastoma Cancer Stem Cell Expression and Invasive Phenotype Mol. Cancer Res., June 1, 2008; 6(6): 907 - 916. [Abstract] [Full Text] [PDF]

				N. Pottier, C. Chupin, V. Defamie, B. Cardinaud, R. Sutherland, G. Rios, F. Gauthier, P. J. Wolters, Y. Berthiaume, P. Barbry, et al. Relationships between Early Inflammatory Response to Bleomycin and Sensitivity to Lung Fibrosis: A Role for Dipeptidyl-Peptidase I and Tissue Inhibitor of Metalloproteinase-3? Am. J. Respir. Crit. Care Med., December 1, 2007; 176(11): 1098 - 1107. [Abstract] [Full Text] [PDF]

				Y.-P. Han, C. Yan, L. Zhou, L. Qin, and H. Tsukamoto A Matrix Metalloproteinase-9 Activation Cascade by Hepatic Stellate Cells in Trans-differentiation in the Three-dimensional Extracellular Matrix J. Biol. Chem., April 27, 2007; 282(17): 12928 - 12939. [Abstract] [Full Text] [PDF]

				J.-M. Park, A. Kim, J.-H. Oh, and A.-S. Chung Methylseleninic acid inhibits PMA-stimulated pro-MMP-2 activation mediated by MT1-MMP expression and further tumor invasion through suppression of NF-{kappa}B activation Carcinogenesis, April 1, 2007; 28(4): 837 - 847. [Abstract] [Full Text] [PDF]

				L. Connelly, C. Robinson-Benion, M. Chont, L. Saint-Jean, H. Li, V. V. Polosukhin, T. S. Blackwell, and F. E. Yull A Transgenic Model Reveals Important Roles for the NF-{kappa}B Alternative Pathway (p100/p52) in Mammary Development and Links to Tumorigenesis J. Biol. Chem., March 30, 2007; 282(13): 10028 - 10035. [Abstract] [Full Text] [PDF]

				Y. Onai, J.-i. Suzuki, Y. Maejima, G. Haraguchi, S. Muto, A. Itai, and M. Isobe Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction Am J Physiol Heart Circ Physiol, January 1, 2007; 292(1): H530 - H538. [Abstract] [Full Text] [PDF]

				R. Sharony, G. Pintucci, P. C. Saunders, E. A. Grossi, F. G. Baumann, A. C. Galloway, and P. Mignatti Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2 Am J Physiol Heart Circ Physiol, April 1, 2006; 290(4): H1651 - H1659. [Abstract] [Full Text] [PDF]

				A. M. Manso, L. Elsherif, S.-M. Kang, and R. S. Ross Integrins, membrane-type matrix metalloproteinases and ADAMs: Potential implications for cardiac remodeling Cardiovasc Res, February 15, 2006; 69(3): 574 - 584. [Abstract] [Full Text] [PDF]

				Y. Ben-Yosef, A. Miller, S. Shapiro, and N. Lahat Hypoxia of endothelial cells leads to MMP-2-dependent survival and death Am J Physiol Cell Physiol, November 1, 2005; 289(5): C1321 - C1331. [Abstract] [Full Text] [PDF]

				P. Gerke, L. Sellin, O. Kretz, D. Petraschka, H. Zentgraf, T. Benzing, and G. Walz NEPH2 Is Located at the Glomerular Slit Diaphragm, Interacts with Nephrin and Is Cleaved from Podocytes by Metalloproteinases J. Am. Soc. Nephrol., June 1, 2005; 16(6): 1693 - 1702. [Abstract] [Full Text] [PDF]

				S. Saika, T. Miyamoto, O. Yamanaka, T. Kato, Y. Ohnishi, K. C. Flanders, K. Ikeda, Y. Nakajima, W. W.-Y. Kao, M. Sato, et al. Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-{kappa}B, in Treatment of Corneal Alkali Burns in Mice Am. J. Pathol., May 1, 2005; 166(5): 1393 - 1403. [Abstract] [Full Text] [PDF]

				A. Mazzocca, S. C. Sciammetta, V. Carloni, L. Cosmi, F. Annunziato, T. Harada, S. Abrignani, and M. Pinzani Binding of Hepatitis C Virus Envelope Protein E2 to CD81 Up-regulates Matrix Metalloproteinase-2 in Human Hepatic Stellate Cells J. Biol. Chem., March 25, 2005; 280(12): 11329 - 11339. [Abstract] [Full Text] [PDF]

				R. Lobmann, G. Schultz, and H. Lehnert Proteases and the Diabetic Foot Syndrome: Mechanisms and Therapeutic Implications Diabetes Care, February 1, 2005; 28(2): 461 - 471. [Full Text] [PDF]

				S. G. Park, H. Shin, Y. K. Shin, Y. Lee, E.-C. Choi, B.-J. Park, and S. Kim The Novel Cytokine p43 Stimulates Dermal Fibroblast Proliferation and Wound Repair Am. J. Pathol., February 1, 2005; 166(2): 387 - 398. [Abstract] [Full Text] [PDF]

				S. Meiners, B. Hocher, A. Weller, M. Laule, V. Stangl, C. Guenther, M. Godes, A. Mrozikiewicz, G. Baumann, and K. Stangl Downregulation of Matrix Metalloproteinases and Collagens and Suppression of Cardiac Fibrosis by Inhibition of the Proteasome Hypertension, October 1, 2004; 44(4): 471 - 477. [Abstract] [Full Text] [PDF]

				Z. Xie, M. Singh, and K. Singh Differential Regulation of Matrix Metalloproteinase-2 and -9 Expression and Activity in Adult Rat Cardiac Fibroblasts in Response to Interleukin-1{beta} J. Biol. Chem., September 17, 2004; 279(38): 39513 - 39519. [Abstract] [Full Text] [PDF]

				A. Thathiah, M. Brayman, N. Dharmaraj, J. J. Julian, E. L. Lagow, and D. D. Carson Tumor Necrosis Factor {alpha} Stimulates MUC1 Synthesis and Ectodomain Release in a Human Uterine Epithelial Cell Line Endocrinology, September 1, 2004; 145(9): 4192 - 4203. [Abstract] [Full Text] [PDF]

				S. Amin, N. H. V. Chong, T. A. Bailey, J. Zhang, C. Knupp, M. E. Cheetham, J. Greenwood, and P. J. Luthert Modulation of Sub-RPE Deposits In Vitro: A Potential Model for Age-Related Macular Degeneration Invest. Ophthalmol. Vis. Sci., May 1, 2004; 45(5): 1281 - 1288. [Abstract] [Full Text] [PDF]

				I. A. Arenas, Y. Xu, P. Lopez-Jaramillo, and S. T. Davidge Angiotensin II-induced MMP-2 release from endothelial cells is mediated by TNF-{alpha} Am J Physiol Cell Physiol, April 1, 2004; 286(4): C779 - C784. [Abstract] [Full Text] [PDF]

				H. M. Wang, X. Zhang, D. Qian, H. Y. Lin, Q. L. Li, D. L. Liu, G. Y. Liu, X. D. Yu, and C. Zhu Effect of Ubiquitin-Proteasome Pathway on Mouse Blastocyst Implantation and Expression of Matrix Metalloproteinases-2 and -9 Biol Reprod, February 1, 2004; 70(2): 481 - 487. [Abstract] [Full Text] [PDF]

				Z. Xie, M. Singh, D. A. Siwik, W. L. Joyner, and K. Singh Osteopontin Inhibits Interleukin-1{beta}-stimulated Increases in Matrix Metalloproteinase Activity in Adult Rat Cardiac Fibroblasts: ROLE OF PROTEIN KINASE C-{zeta} J. Biol. Chem., December 5, 2003; 278(49): 48546 - 48552. [Abstract] [Full Text] [PDF]

				W. Gu, D. Weihrauch, K. Tanaka, J. P. Tessmer, P. S. Pagel, J. R. Kersten, W. M. Chilian, and D. C. Warltier Reactive oxygen species are critical mediators of coronary collateral development in a canine model Am J Physiol Heart Circ Physiol, October 1, 2003; 285(4): H1582 - H1589. [Abstract] [Full Text] [PDF]

				B.-W. Wang, H. Chang, S. Lin, P. Kuan, and K.-G. Shyu Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-{alpha} in cultured human umbilical vein endothelial cells Cardiovasc Res, August 1, 2003; 59(2): 460 - 469. [Abstract] [Full Text] [PDF]

				X. Liao, J. B. Thrasher, J. Pelling, J. Holzbeierlein, Q.-X. A. Sang, and B. Li Androgen Stimulates Matrix Metalloproteinase-2 Expression in Human Prostate Cancer Endocrinology, May 1, 2003; 144(5): 1656 - 1663. [Abstract] [Full Text] [PDF]

				M. Hirata, T. Sato, M. Tsumagari, A. Shimada, H. Nakano, K. Hashizume, and A. Ito Differential Regulation of the Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases by Cytokines and Growth Factors in Bovine Endometrial Stromal Cells and Trophoblast Cell Line BT-1 In Vitro Biol Reprod, April 1, 2003; 68(4): 1276 - 1281. [Abstract] [Full Text] [PDF]

				V. Poulaki, C. S. Mitsiades, A. M. Joussen, A. Lappas, B. Kirchhof, and N. Mitsiades Constitutive Nuclear Factor-{kappa}B Activity Is Crucial for Human Retinoblastoma Cell Viability Am. J. Pathol., December 1, 2002; 161(6): 2229 - 2240. [Abstract] [Full Text] [PDF]

				A.-M. Khatib, L. Fallavollita, E. V. Wancewicz, B. P. Monia, and P. Brodt Inhibition of Hepatic Endothelial E-Selectin Expression by C-raf Antisense Oligonucleotides Blocks Colorectal Carcinoma Liver Metastasis Cancer Res., October 1, 2002; 62(19): 5393 - 5398. [Abstract] [Full Text] [PDF]

				P. O. Esteve, E. Chicoine, O. Robledo, F. Aoudjit, A. Descoteaux, E. F. Potworowski, and Y. St-Pierre Protein Kinase C-zeta Regulates Transcription of the Matrix Metalloproteinase-9 Gene Induced by IL-1 and TNF-alpha in Glioma Cells via NF-kappa B J. Biol. Chem., September 13, 2002; 277(38): 35150 - 35155. [Abstract] [Full Text] [PDF]

				Y.-P. Han, Y.-D. Nien, and W. L. Garner Tumor Necrosis Factor-alpha -induced Proteolytic Activation of Pro-matrix Metalloproteinase-9 by Human Skin Is Controlled by Down-regulating Tissue Inhibitor of Metalloproteinase-1 and Mediated by Tissue-associated Chymotrypsin-like Proteinase J. Biol. Chem., July 19, 2002; 277(30): 27319 - 27327. [Abstract] [Full Text] [PDF]

				N. Mitsiades, C. S. Mitsiades, V. Poulaki, D. Chauhan, P. G. Richardson, T. Hideshima, N. Munshi, S. P. Treon, and K. C. Anderson Biologic sequelae of nuclear factor-kappa B blockade in multiple myeloma: therapeutic applications Blood, May 13, 2002; 99(11): 4079 - 4086. [Abstract] [Full Text] [PDF]