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Boyce, B. F., Yoneda, T., Lowe, C., Soriano, P. and Mundy, G. R (1992). Requirement of pp60c-srcexpression for osteoclasts to form ruffled borders and resorb bone in mice. J. Clin. Invest 90, 1622-1627.

Bockholt, S. M. and Burrudge, K (1995). An examination of focal adhesion formation and tyrosine phosphorylation in fibroblasts isolated from src-, fyn-, and yes-mice. Cell Adhesion Commun 3, 91-100.[Medline]

Chambers, T. J. and Hall, T. J (1991). Cellular and molecular mechanisms in the regulation and function of osteoclasts. Vitam. Horm 46, 41-86.[Medline]

Davies, J., Warwick, J., Totty, N., Philp, R., Helfrich, M. and Horton, M (1989). The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor. J. Cell Biol 109, 1817-1826.[Abstract/Free Full Text]

Duong, L. T., Lakkakorpi, P. T., Nakamura, I., Machwate, M., Nagy, R. M. and Rodan, G. A (1998). PYK2 in osteoclasts is an adhesion kinase, localized in the sealing zone, activated by ligation ofv 3integrin, and phosphorylated by Src kinase. J. Clin. Invest 102, 881-892.[Medline]

Fincham, V. J. and Frame, M. C (1998). The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility. EMBO J 17, 81-92.[Medline]

Fuortes, M., Melchior, M., Han, H., Lyon, G. J. and Nathan, C (1999). Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. J. Clin. Invest 104, 327-335.[Medline]

Horne, W. C., Neff, L., Chatterjee, D., Lomri, A., Levy, J. B. and Baron, R (1992). Osteoclast express high levels of pp60c-srcin association with intracellular membranes. J.Cell Biol 119, 1003-1013.[Abstract/Free Full Text]

Ilic, D., Furuta, Y., Kanazawa, S., Takeda, N., Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., Yamamoto, T. and Aizawa, S (1995). Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377, 539-544.[Medline]

Insogna, K. L., Sahni, M., Grey, A. B., Tanaka, S., Horne, W. C., Neff, L., Mitnick, M., Levy, J. B. and Baron, R (1997). Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts. J. Clin. Invest 100, 2476-2485.[Medline]

Kaplan, K. B., Swedlow, J. R., Morgan, D. O. and Varmus, H. E (1995). c-Src enhances the spreading of src/ fibroblasts on fibronectin by a kinase-independent mechanism. Genes Dev 9, 1505-1517.[Abstract/Free Full Text]

Klinghoffer, R. A., Sachsenmaier, C., Cooper, J. A. and Soriano, P (1999). Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J 18, 2459-2471.[Medline]

Lakkakorpi, P. T. and V\212\212n\212nen, H. K (1991). Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro. J. Bone Miner. Res 6, 817-826.[Medline]

Lakkakorpi, P., Tuukkanen, J., Hentunen, T., J\212rvelin, K. and V\212\212n\212nen, K (1989). Organization of osteoclast microfilaments during the attachment to bone surface in vitro. J. Bone Miner. Res 4, 817-825.[Medline]

Lakkakorpi, P. T., Horton, M. A., Helfrich, M. H., Karhukorpi, E.-K. and V\212\212n\212nen, H. K (1991). Vitronectin receptor has a role in bone resorption but does not mediate tight sealing zone attachment of osteoclasts to the bone surface. J. Cell Biol 115, 1179-1186.[Abstract/Free Full Text]

Lakkakorpi, P. T., Nakamura, I., Nagy, R. M., Parsons, J. T., Rodan, G. A. and Duong, L. T (1999). Stable association of PYK2 and p130Casin osteoclasts and their co-localization in the sealing zone. J. Biol. Chem 274, 4900-4907.[Abstract/Free Full Text]

Lehenkari, P. P. and Horton, M. A (1999). Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy. Biochem. Biophys. Res. Commun 259, 645-650.[Medline]

Lowe, C., Yoneda, T., Boyce, B. F., Chen, H., Mundy, G. R. and Soriano, P (1993). Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts. Proc. Natl. Acad. Sci. USA 90, 4485-4489.[Abstract/Free Full Text]

Lowell, C. A., Niwa, M., Soriano, P. and Varmus, H. E (1996). Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis. Blood 87, 1780-1792.[Abstract/Free Full Text]

Marhaba, R., Mary, F., Pelassy, C., Stanescu, A. T., Aussel, C. and Breittmayer, J.-P (1996). Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells. J. Immunol 157, 1468-1473.[Abstract]

Masarachia, P., Yamamoto, M., Rodan, G. A. and Duong, L. T (1995). Co-localization of the vitronectin receptorv 3and echistatin in osteoclasts during bone resoption in vivo. J. Bone Miner. Res 10, 164-.[Medline]

McHugh, K. P., Hodivala-Dilke, K., Zheng, M.-H., Namba N., Lam, J., Novack, D., Feng, X., Ross, F. P., Hynes, R. O. and Teitelbaum, S. L (2000). Mice lacking3integrins are osteosclerotic because of dysfunctional osteoclasts. J. Clin. Invest 105, 433-440.[Medline]

Miyazaki, T., Takayanagi, H., Isshiki, M., Takahashi, T., Okada, M., Fukui, Y., Oda, H., Nakamura, K., Hirai, H., Kurokawa, T. and Tanaka, S (2000). In vitro and in vivo suppression of osteoclast function by adenovirus vector induced csk gene. J. Bone Miner. Res 15, 41-51.[Medline]

Nakamoto, T., Sakai, R., Honda, H., Ogawa, S., Ueno, H., Suzuki, T.,Aizawa, S.-I., Yazaki, Y. and Hirai, H (1997). Requirements for localization of p130casto focal adhesions. Mol. Cell. Biol 17, 3884-3897.[Abstract]

Nakamura, I., Jimi, E., Duong, L. T., Sasaki, T., Takahashi, N., Rodan, G. A. and Suda, T (1998). Tyrosine phosphorylation of p130Casis involved in actin ring organization in osteoclasts. J. Biol. Chem 273, 11144-11149.[Abstract/Free Full Text]

Nakamura, I., Pilkington, M. F., Lakkakorpi, P. T., Lipfert, L., Sims, S. M., Dixon, S. J., Rodan, G. A. and Duong, L. T (1999). Role ofv 3integrin in osteoclast migration and formation of the sealing zone. J. Cell Sci 112, 3985-3993.[Abstract]

Nesbitt, S. A. and Horton, M. A (1997). Trafficking of matrix collagens through bone-resorbing osteoclasts. Science 276, 266-269.[Abstract/Free Full Text]

Roodman, G. D (1999). Cell biology of the osteoclast. Exp. Hematol 27, 1229-1241.[Medline]

Salo, J., Lehenkari, P., Mulari, M., Metsikk\232, K. and V\212\212n\212nen, H. K (1997). Removal of osteoclast bone resorption products by transcytosis. Science 276, 270-273.[Abstract/Free Full Text]

Sato, M., Sardana, M. K., Grasser, W. A., Garsky, V. M., Murray, J. M. and Gould, R. J (1990). Echistatin is a potent inhibitor of bone resorption in culture. J. Cell Biol 111, 1713-1723.[Abstract/Free Full Text]

Schaller, M. D., Hildebrand, J. D. and Parsons, J. T (1999). Complexformation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases. Mol. Biol. Cell 10, 3489-3505.[Abstract/Free Full Text]

Schwartzberg, P. L., Xing, L., Hoffmann, O., Lowell, C. A., Garrett, L., Boyce, B. F. and Varmus, H. E (1997). Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src/ mutant mice. Genes Dev 11, 2835-2844.[Abstract/Free Full Text]

Soriano, P., Montgomery, C., Geske, R. and Bradley, A (1991). Targeted disruption of the c-src protooncogene leads to osteopetrosis in mice. Cell 64, 693-702.[Medline]

Suda, T., Nakamura, I., Jimi, E. and Takahashi, N (1997). Regulation of osteoclast function. J. Bone Miner. Res 12, 869-879.[Medline]

Tanaka, S., Takahashi, N., Udagawa, N., Sasaki, T., Fukui, Y., Kurokawa, T. and Suda, T (1992). Osteoclasts express high levels of p60c-src, preferentially on ruffled border membranes. FEBS Lett 313, 85-89.[Medline]

Tanaka, S., Amling, M., Neff, L., Peyman, A., Uhlman, E., Levy, J. B. and Baron, R (1996). c-Cbl is downstream of c-Src in a signaling pathway necessary for bone resorption. Nature 383, 528-531.[Medline]

Wesolowski, G., Duong, L. T., Lakkakorpi, P. T., Nagy, R. M., Tezuka, K., Tanaka, H., Rodan, G. A. and Rodan, S. B (1995). Isolation and characterization of highly enriched, prefusion mouse osteoclastic cells. Exp. Cell Res 219, 679-686.[Medline]


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