spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Klibanov, S. A.
Right arrow Articles by Ljungman, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Klibanov, S. A.
Right arrow Articles by Ljungman, M.
Ashcroft, M., Taya, Y. and Vousden, K. H (2000). Stress signals utilize multiple pathways to stabilize p53. Mol. Cell. Biol 20, 3224-3233.[Abstract/Free Full Text]

Blagosklonny, M. V., Wu, G. S., Omura, S. and El-Deiry, W. S (1996). Proteasome-dependent regulation of p21WAF1/CIP1 expression. Biochem. Biophys. Res. Commun 227, 564-569.[Medline]

Blaydes, J. P., Craig, A. L., Wallace, M., Ball, H. M., Traynor, N., Gibbs, J. N. K. and Hupp, T. R (2000). Synergistic activation of p53-dependent transcription by two cooperating damage recognition pathways. Oncogene 19, 3829-3839.[Medline]

Brasch, K (1990). Drug and metabolite-induced perturbations in nuclear structure and function: a review. Biochem. Cell Biol 68, 408-426.[Medline]

Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W. and Vogelstein, B (1998). Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282, 1497-1501.[Abstract/Free Full Text]

Chehab, N. H., Malikzay, A., Appel, M. and Halazonetis, T. D (2000). Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 14, 278-288.[Abstract/Free Full Text]

Chehab, N. H., Malikzay, A., Stavridi, E. S. and Halazonetis, T. D (1999). Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc. Natl. Acad. Sci. USA 96, 13777-13782.[Abstract/Free Full Text]

Chen, F., Chang, D., Goh, M., Klibanov, S. A. and Ljungman, M (2000). Role of p53 in cell cycle regulation and apoptosis following exposure to proteasome inhibitors. Cell Growth Differ 11, 239-246.[Abstract/Free Full Text]

Dulic, V., Kaufmann, W. K., Wilson, S. J., Tlsty, T. D., Lees, E., Harper, J. W., Elledge, S. J. and Reed, S. I (1994). p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76, 1013-1023.[Medline]

Dumaz, N. and Meek, D. W (1999). Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2. EMBO J 18, 7002-7010.[Medline]

Freedman, D. A., Wu, L. and Levine, A. J (1999). Functions of the MDM2 oncoprotein. Cell. Mol. Life Sci 55, 96-107.[Medline]

Fritsche, M., Haessler, C. and Brandner, G (1993). Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents. Oncogene 8, 307-318.[Medline]

Fuchs, S. Y., Adler, V., Buschmann, T., Yin, Z. M., Wu, X. W., Jones, S. N. and Ronai, Z (1998). JNK targets p53 ubiquitination and degradation in nonstressed cells. Genes Dev 12, 2658-2663.[Abstract/Free Full Text]

Giaccia, A. J. and Kastan, M. B (1998). The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev 12, 2973-2983.[Free Full Text]

Ginisty, H., Sicard, H., Roger, B. and Bouvet, P (1999). Structure and functions of nucleolin. J. Cell Sci 112, 761-772.[Abstract]

Haaf, T. and Ward, D. C (1996). Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains. Exp. Cell Res 224, 163-173.[Medline]

Haupt, Y., Maya, R., Kazaz, A. and Oren, M (1997). Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299.[Medline]

Hirao, A., Kong, Y. Y., Matsuoka, S., Wakeham, A., Ruland, J., Yoshida, H., Liu, D., Elledge, S. J. and Mak, T. W (2000). DNA damage-induced activation of p53 by the checkpoint kinase chk2. Science 287, 1824-1827.[Abstract/Free Full Text]

Hupp, T., Meek, D., Midgley, C. and Lane, D (1992). Regulation of the specific DNA binding function of p53. Cell 71, 875-886.[Medline]

Hwang, B. J., Ford, J. M., Hanawalt, P. C. and Chu, G (1999). Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc. Natl. Acad. Sci. USA 96, 424-428.[Abstract/Free Full Text]

Jayaraman, L. and Prives, C (1999). Covalent and noncovalent modifiers of the p53 protein. Cell. Mol. Life Sci 55, 76-87.[Medline]

Kubbutat, M. H. G., Jones, S. N. and Vousden, K. H (1997). Regulation of p53 stability by Mdm2. Nature 387, 299-303.[Medline]

Li, L., Ljungman, M. and Dixon, J. E (2000). The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53. J. Biol. Chem 275, 2410-2414.[Abstract/Free Full Text]

Liu, L., Scolnick, D. M. Trievel, R. C., Zhang, H. B., Marmorstein, R., Halazonetis, T. D. and Berger, S. L (1999). p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol. Cell. Biol 19, 1202-1209.[Abstract/Free Full Text]

Ljungman, M. and Zhang, F (1996). Blockage of RNA polymerase as a possible trigger for uv light-induced apoptosis. Oncogene 13, 823-831.[Medline]

Ljungman, M., Zhang, F. F., Chen, F., Rainbow, A. J. and McKay, B. C (1999). Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene 18, 583-592.[Medline]

Lu, X., Burbidge, S. A., Griffin, S. and Smith, H. M (1996). Discordance between accumulated p53 protein level and its transcriptional activity in response to uv radiation. Oncogene 13, 413-418.[Medline]

Lu, X. and Lane, D. P (1993). Differential induction of transcriptionally active p53 following UV or ionizing radiation- Defects in chromosome instability syndromes?. Cell 75, 765-778.[Medline]

Magae, J., Illenye, S., Tejima, T., Chang, Y. C., Mitsui, Y., Tanaka, K., Omura, S. and Heintz, N. H (1997). Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin. Oncogene 15, 759-769.[Medline]

Maki, C. G., Huibregtse, J. M. and Howley, P. M (1996). In vivo ubiquitination and proteasome-mediated degradation of p53. Cancer Res 56, 2649-2654.[Abstract/Free Full Text]

Maltzman, W. and Czyzyk, L (1984). UV irradiation stimulates levels of p53 cellular antigen in nontransformed mouse cells. Mol. Cell. Biol 4, 1689-1694.[Abstract/Free Full Text]

McKay, B. C., Ljungman, M. and Rainbow, A. J (1998). Persistent DNA damage induced by ultraviolet light inhibits p21(waf1) and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis. Oncogene 17, 545-555.[Medline]

Miyashita, T. and Reed, J. C (1995). Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.[Medline]

Perry, M., Piette, J., Zawadzki, J., Harvey, D. and Levine, A (1993). The mdm-2 gene is induced in response to UV light in a p53-dependent manner. Proc. Natl. Acad. Sci. USA 90, 11623-11627.[Abstract/Free Full Text]

Phair, R. and Misteli, T (2000). High mobility of proteins in the mammalian cell nucleus. Nature 404, 604-609.[Medline]

Reinke, V. and Lozano, G (1997). Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest. Radiat. Res 148, 115-122.[Medline]

Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T. and Levine, A. J (1998). Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J 17, 554-564.[Medline]

Rubbi, C. P. and Milner, J (2000). Non-activated p53 co-localizes with sites of transcription within both the nucleoplasm and the nucleolus. Oncogene 19, 85-96.[Medline]

Sakaguchi, K., Herrera, J. E., Saito, S., Miki, T., Bustin, M., Vassilev, A., Anderson, C. W. and Appella, E (1998). DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev 12, 2831-2841.[Abstract/Free Full Text]

Sakaguchi, K., Saito, S., Higashimoto, Y., Roy, S. C., Anderson, W. and Appella, E (2000). Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase- Effect on Mdm2 binding. J. Biol. Chem 275, 9278-9283.[Abstract/Free Full Text]

Shieh, S. Y., Ahn, J., Tamai, K., Taya, Y. and Prives, C (2000). The human homologs of checkpoint kinases chk1 and cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev 14, 289-300.[Abstract/Free Full Text]

Shieh, S. Y., Ikeda, M., Taya, Y. and Prives, C (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334.[Medline]

Siliciano, J. D., Canman, C. E., Taya, Y., Sakaguchi, K., Appella, E. and Kastan, M. B (1997). DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev 11, 3471-3481.[Abstract/Free Full Text]

Smith, M. L., Ford, J. M., Hollander, M. C., Bortnick, R. A., Amundson, S. A., Seo, Y. R., Deng, C. X., Hanawalt, P. C. and Fornace, A. J., Jr (2000). p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Mol. Cell. Biol 20, 3705-3714.[Abstract/Free Full Text]

Tao, W. K. and Levine,A. J (1999). Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proc. Natl. Acad. Sci. USA 96, 3077-3080.[Abstract/Free Full Text]

Unger, T., Juven-Gershon, T., Moallem, E., Berger, M., Sionov, R. V., Lozano, G., Oren, M. and Haupt, Y (1999). Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. EMBO J 18, 1805-1814.[Medline]

Wu, G. S., Burns, T. F., McDonald, E. R., Jiang, W., Meng, R., Krantz, I. D., Kao, G., Gan, D. D., Zhou, J. Y., Muschel, R. et al (1997). KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat. Genet 17, 141-143.[Medline]

Zimmermann, J., Erdmann, D., Lalande, I., Grossenbacher, R., Noorani, M. and Furst, P (2000). Proteasome inhibitor induced gene expression profiles reveal overexpression of transcriptional regulators ATF3, GADD153 and MAD1. Oncogene 19, 2913-2920.[Medline]




This article has been cited by other articles:


Home page
J. Biol. Chem.Home page
M. Xie, I. Kobayashi, T. Kiyoshima, H. Yamaza, J.-y. Honda, K. Takahashi, N. Enoki, A. Akamine, and H. Sakai
Functional Implication of Nucleolin in the Mouse First Molar Development
J. Biol. Chem., August 10, 2007; 282(32): 23275 - 23283.
[Abstract] [Full Text] [PDF]


Home page
Nucleic Acids ResHome page
K. M. Viiri, H. Korkeamaki, M. K. Kukkonen, L. K. Nieminen, K. Lindfors, P. Peterson, M. Maki, H. Kainulainen, and O. Lohi
SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus
Nucleic Acids Res., July 4, 2006; 34(11): 3288 - 3298.
[Abstract] [Full Text] [PDF]


Home page
Nucleic Acids ResHome page
T. Grimm, M. Holzel, M. Rohrmoser, T. Harasim, A. Malamoussi, A. Gruber-Eber, E. Kremmer, and D. Eick
Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex
Nucleic Acids Res., May 31, 2006; 34(10): 3030 - 3043.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
S. T. Al Rashid, G. Dellaire, A. Cuddihy, F. Jalali, M. Vaid, C. Coackley, M. Folkard, Y. Xu, B. P.C. Chen, D. J. Chen, et al.
Evidence for the Direct Binding of Phosphorylated p53 to Sites of DNA Breaks In vivo
Cancer Res., December 1, 2005; 65(23): 10810 - 10821.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
L. A. Stark and M. G. Dunlop
Nucleolar Sequestration of RelA (p65) Regulates NF-{kappa}B-Driven Transcription and Apoptosis
Mol. Cell. Biol., July 15, 2005; 25(14): 5985 - 6004.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
P.-O. Esteve, H. G. Chin, and S. Pradhan
Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters
PNAS, January 25, 2005; 102(4): 1000 - 1005.
[Abstract] [Full Text] [PDF]


Home page
Mol Biol EvolHome page
G. H.Y. He, C. C. Helbing, M. J. Wagner, C. W. Sensen, and K. Riabowol
Phylogenetic Analysis of the ING Family of PHD Finger Proteins
Mol. Biol. Evol., January 1, 2005; 22(1): 104 - 116.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
S. Kurki, L. Latonen, and M. Laiho
Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization
J. Cell Sci., October 1, 2003; 116(19): 3917 - 3925.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. K. Chatterjee and R. A. Fisher
Mild Heat and Proteotoxic Stress Promote Unique Subcellular Trafficking and Nucleolar Accumulation of RGS6 and Other RGS Proteins: ROLE OF THE RGS DOMAIN IN STRESS-INDUCED TRAFFICKING OF RGS PROTEINS
J. Biol. Chem., August 8, 2003; 278(32): 30272 - 30282.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
T. Hideshima, C. Mitsiades, M. Akiyama, T. Hayashi, D. Chauhan, P. Richardson, R. Schlossman, K. Podar, N. C. Munshi, N. Mitsiades, et al.
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
Blood, February 15, 2003; 101(4): 1530 - 1534.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
Y. H. Kwon, A. Jovanovic, M. S. Serfas, H. Kiyokawa, and A. L. Tyner
p21 Functions to Maintain Quiescence of p27-deficient Hepatocytes
J. Biol. Chem., October 25, 2002; 277(44): 41417 - 41422.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
G. Romeo, W.-H. Liu, V. Asnaghi, T. S. Kern, and M. Lorenzi
Activation of Nuclear Factor-{kappa}B Induced by Diabetes and High Glucose Regulates a Proapoptotic Program in Retinal Pericytes
Diabetes, July 1, 2002; 51(7): 2241 - 2248.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Klibanov, S. A.
Right arrow Articles by Ljungman, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Klibanov, S. A.
Right arrow Articles by Ljungman, M.