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Phosphorylation Regulates Tau Interactions with Src Homology 3 Domains of Phosphatidylinositol 3-Kinase, Phospholipase C{gamma}1, Grb2, and Src Family Kinases
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K. Haberg, R. Lundmark, and S. R. Carlsson
SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking
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Nucleic Acids ResHome page
J. Guo, X. Wu, D.-Y. Zhang, and K. Lin
Genome-wide inference of protein interaction sites: lessons from the yeast high-quality negative protein-protein interaction dataset
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I. Y. Churbanova and I. F. Sevrioukova
Redox-dependent Changes in Molecular Properties of Mitochondrial Apoptosis-inducing Factor
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JCBHome page
P. M. Benz, C. Blume, J. Moebius, C. Oschatz, K. Schuh, A. Sickmann, U. Walter, S. M. Feller, and T. Renne
Cytoskeleton assembly at endothelial cell cell contacts is regulated by {alpha}II-spectrin VASP complexes
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Y. Zhou, W. Yang, M. M. Lurtz, Y. Ye, Y. Huang, H.-W. Lee, Y. Chen, C. F. Louis, and J. J. Yang
Identification of the Calmodulin Binding Domain of Connexin 43
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D. E. Shvartsman, J. C. Donaldson, B. Diaz, O. Gutman, G. S. Martin, and Y. I. Henis
Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets
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S. Z. Imam, F. E. Indig, W.-H. Cheng, S. P. Saxena, T. Stevnsner, D. Kufe, and V. A. Bohr
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase
Nucleic Acids Res., August 1, 2007; 35(15): 4941 - 4951.
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E. Ferraro, D. Peluso, A. Via, G. Ausiello, and M. Helmer-Citterich
SH3-Hunter: discovery of SH3 domain interaction sites in proteins
Nucleic Acids Res., July 13, 2007; 35(suppl_2): W451 - W454.
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GeneticsHome page
J. Haynes, B. Garcia, E. J. Stollar, A. Rath, B. J. Andrews, and A. R. Davidson
The Biologically Relevant Targets and Binding Affinity Requirements for the Function of the Yeast Actin-Binding Protein 1 Src-Homology 3 Domain Vary With Genetic Context
Genetics, May 1, 2007; 176(1): 193 - 208.
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K.-J. Hwang, F. Mahmoodian, J. A. Ferretti, E. D. Korn, and J. M. Gruschus
Intramolecular interaction in the tail of Acanthamoeba myosin IC between the SH3 domain and a putative pleckstrin homology domain
PNAS, January 16, 2007; 104(3): 784 - 789.
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G. Moncalian, N. Cardenes, Y. L. Deribe, M. Spinola-Amilibia, I. Dikic, and J. Bravo
Atypical Polyproline Recognition by the CMS N-terminal Src Homology 3 Domain
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FASEB J.Home page
L. Tian, L. Chen, H. McClafferty, C. A. Sailer, P. Ruth, H.-G. Knaus, and M. J. Shipston
A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin
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C. Mazzochi, D. J. Benos, and P. R. Smith
Interaction of epithelial ion channels with the actin-based cytoskeleton
Am J Physiol Renal Physiol, December 1, 2006; 291(6): F1113 - F1122.
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Eukaryot CellHome page
P. Knechtle, J. Wendland, and P. Philippsen
The SH3/PH Domain Protein AgBoi1/2 Collaborates with the Rho-Type GTPase AgRho3 To Prevent Nonpolar Growth at Hyphal Tips of Ashbya gossypii
Eukaryot. Cell, October 1, 2006; 5(10): 1635 - 1647.
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BioinformaticsHome page
E. Ferraro, A. Via, G. Ausiello, and M. Helmer-Citterich
A novel structure-based encoding for machine-learning applied to the inference of SH3 domain specificity
Bioinformatics, October 1, 2006; 22(19): 2333 - 2339.
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H. Konishi, K. Tashiro, Y. Murata, H. Nabeshi, E. Yamauchi, and H. Taniguchi
CFBP Is a Novel Tyrosine-phosphorylated Protein That Might Function as a Regulator of CIN85/CD2AP
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X. Li, Y. Chen, Y. Liu, J. Gao, F. Gao, M. Bartlam, J. Y. Wu, and Z. Rao
Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway
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J. Zhou, J. Fan, and J.-T. Hsieh
Inhibition of Mitogen-Elicited Signal Transduction and Growth in Prostate Cancer with a Small Peptide Derived from the Functional Domain of DOC-2/DAB2 Delivered by a Unique Vehicle.
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K. Ma, J. G. Forbes, G. Gutierrez-Cruz, and K. Wang
Titin as a Giant Scaffold for Integrating Stress and Src Homology Domain 3-mediated Signaling Pathways: THE CLUSTERING OF NOVEL OVERLAP LIGAND MOTIFS IN THE ELASTIC PEVK SEGMENT
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BioinformaticsHome page
J. L. Morrison, R. Breitling, D. J. Higham, and D. R. Gilbert
A lock-and-key model for protein-protein interactions
Bioinformatics, August 15, 2006; 22(16): 2012 - 2019.
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A High Efficiency Strategy for Binding Property Characterization of Peptide-binding Domains
Mol. Cell. Proteomics, August 1, 2006; 5(8): 1368 - 1381.
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M. R. Schiller, K. Chakrabarti, G. F. King, N. I. Schiller, B. A. Eipper, and M. W. Maciejewski
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An Integrated Machine Learning System to Computationally Screen Protein Databases for Protein Binding Peptide Ligands
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Regulation and Function of SKAP-55 Non-canonical Motif Binding to the SH3c Domain of Adhesion and Degranulation-promoting Adaptor Protein
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Y. Liang and B. Roizman
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J. Z. Lu, T. Fujiwara, H. Komatsuzawa, M. Sugai, and J. Sakon
Cell Wall-targeting Domain of Glycylglycine Endopeptidase Distinguishes among Peptidoglycan Cross-bridges
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Disease-related Modifications in Tau Affect the Interaction between Fyn and Tau
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C. M. Louie and J. G. Gleeson
Genetic basis of Joubert syndrome and related disorders of cerebellar development
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M. Ralser, U. Nonhoff, M. Albrecht, T. Lengauer, E. E. Wanker, H. Lehrach, and S. Krobitsch
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways
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Novel Src Homology 3 Domain-binding Motifs Identified from Proteomic Screen of a Pro-rich Region
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E. Solomaha, F. L. Szeto, M. A. Yousef, and H. C. Palfrey
Kinetics of Src Homology 3 Domain Association with the Proline-rich Domain of Dynamins: SPECIFICITY, OCCLUSION, AND THE EFFECTS OF PHOSPHORYLATION
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GeneticsHome page
H. Friesen, K. Colwill, K. Robertson, O. Schub, and B. Andrews
Interaction of the Saccharomyces cerevisiae Cortical Actin Patch Protein Rvs167p With Proteins Involved in ER to Golgi Vesicle Trafficking
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K. Okada, S. Kanaya, and K. Asai
Accurate extraction of functional associations between proteins based on common interaction partners and common domains
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E. J. Chenette, A. Abo, and C. J. Der
Critical and Distinct Roles of Amino- and Carboxyl-terminal Sequences in Regulation of the Biological Activity of the Chp Atypical Rho GTPase
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A. Macdonald, S. Mazaleyrat, C. McCormick, A. Street, N. J. Burgoyne, R. M. Jackson, V. Cazeaux, H. Shelton, K. Saksela, and M. Harris
Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling
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M. J. Winters and P. M. Pryciak
Interaction with the SH3 Domain Protein Bem1 Regulates Signaling by the Saccharomyces cerevisiae p21-Activated Kinase Ste20
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R.M. Touyz, G. Yao, M.T. Quinn, P.J. Pagano, and E.L. Schiffrin
p47phox Associates With the Cytoskeleton Through Cortactin in Human Vascular Smooth Muscle Cells: Role in NAD(P)H Oxidase Regulation by Angiotensin II
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S. Bouton, L. Viau, E. Lelievre, and A. M. Limami
A gene encoding a protein with a proline-rich domain (MtPPRD1), revealed by suppressive subtractive hybridization (SSH), is specifically expressed in the Medicago truncatula embryo axis during germination
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Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly
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Y. Li, P. Langlais, N. Gamper, F. Liu, and M. S. Shapiro
Dual Phosphorylations Underlie Modulation of Unitary KCNQ K+ Channels by Src Tyrosine Kinase
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J. C. Lougheed, R.-H. Chen, P. Mak, and T. J. Stout
Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1
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N. P.Y. Lee and C. Y. Cheng
Adaptors, Junction Dynamics, and Spermatogenesis
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B. Li, L. Zhuang, and B. Trueb
Zyxin Interacts with the SH3 Domains of the Cytoskeletal Proteins LIM-nebulette and Lasp-1
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GENES CELLSHome page
S. Yuzawa, N. N. Suzuki, Y. Fujioka, K. Ogura, H. Sumimoto, and F. Inagaki
A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase
Genes Cells, May 1, 2004; 9(5): 443 - 456.
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The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells
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A Novel Proteomic Screen for Peptide-Protein Interactions
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A. Macdonald, K. Crowder, A. Street, C. McCormick, and M. Harris
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
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Protein Eng Des SelHome page
B. Ravi Chandra, R. Gowthaman, R. Raj Akhouri, D. Gupta, and A. Sharma
Distribution of proline-rich (PxxP) motifs in distinct proteomes: functional and therapeutic implications for malaria and tuberculosis
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Akt2 Negatively Regulates Assembly of the POSH-MLK-JNK Signaling Complex
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Structural Insight into Modest Binding of a Non-PXXP Ligand to the Signal Transducing Adaptor Molecule-2 Src Homology 3 Domain
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R. Lundmark and S. R. Carlsson
Sorting Nexin 9 Participates in Clathrin-mediated Endocytosis through Interactions with the Core Components
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Y. Noda, M. Kohjima, T. Izaki, K. Ota, S. Yoshinaga, F. Inagaki, T. Ito, and H. Sumimoto
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K. Kowanetz, I. Szymkiewicz, K. Haglund, M. Kowanetz, K. Husnjak, J. D. Taylor, P. Soubeyran, U. Engstrom, J. E. Ladbury, and I. Dikic
Identification of a Novel Proline-Arginine Motif Involved in CIN85-dependent Clustering of Cbl and Down-regulation of Epidermal Growth Factor Receptors
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P. B. van Hennik, J. P. t. Klooster, J. R. Halstead, C. Voermans, E. C. Anthony, N. Divecha, and P. L. Hordijk
The C-terminal Domain of Rac1 Contains Two Motifs That Control Targeting and Signaling Specificity
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GeneticsHome page
K. Ohkuni, A. Okuda, and A. Kikuchi
Yeast Nap1-Binding Protein Nbp2p Is Required for Mitotic Growth at High Temperatures and for Cell Wall Integrity
Genetics, October 1, 2003; 165(2): 517 - 529.
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ScienceHome page
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Atypical Recognition Consensus of CIN85/SETA/Ruk SH3 Domains Revealed by Target-assisted Iterative Screening
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A Docking Site in MKK4 Mediates High Affinity Binding to JNK MAPKs and Competes with Similar Docking Sites in JNK Substrates
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I. R. Bates, J. M. Boggs, J. B. Feix, and G. Harauz
Membrane-anchoring and Charge Effects in the Interaction of Myelin Basic Protein with Lipid Bilayers Studied by Site-directed Spin Labeling
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Interaction of Guanylyl Cyclase C with SH3 Domain of Src Tyrosine Kinase: YET ANOTHER MECHANISM FOR DESENSITIZATION
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Linking the T Cell Surface Protein CD2 to the Actin-capping Protein CAPZ via CMS and CIN85
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The Direct Interaction of Phospholipase C-gamma 1 with Phospholipase D2 Is Important for Epidermal Growth Factor Signaling
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The Structure and Function of Proline Recognition Domains
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Cav1.3 Is Preferentially Coupled to Glucose-Stimulated Insulin Secretion in the Pancreatic beta -Cell Line INS-1
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M. Hiipakka and K. Saksela
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The Glc7p-Interacting Protein Bud14p Attenuates Polarized Growth, Pheromone Response, and Filamentous Growth in Saccharomyces cerevisiae
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