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J. Pharmacol. Exp. Ther.Home page
N. A. Shahabi, K. McAllen, and B. M. Sharp
{delta} Opioid Receptors Stimulate Akt-Dependent Phosphorylation of c-jun in T Cells
J. Pharmacol. Exp. Ther., February 1, 2006; 316(2): 933 - 939.
[Abstract] [Full Text] [PDF]


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BloodHome page
A. Bilancio, K. Okkenhaug, M. Camps, J. L. Emery, T. Ruckle, C. Rommel, and B. Vanhaesebroeck
Key role of the p110{delta} isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110{delta} function in B cells
Blood, January 15, 2006; 107(2): 642 - 650.
[Abstract] [Full Text] [PDF]


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Mol. Cell. Biol.Home page
F. Fiory, A. T. Alberobello, C. Miele, F. Oriente, I. Esposito, V. Corbo, M. Ruvo, B. Tizzano, T. E. Rasmussen, S. Gammeltoft, et al.
Tyrosine Phosphorylation of Phosphoinositide-Dependent Kinase 1 by the Insulin Receptor Is Necessary for Insulin Metabolic Signaling
Mol. Cell. Biol., December 15, 2005; 25(24): 10803 - 10814.
[Abstract] [Full Text] [PDF]


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J. Cell Sci.Home page
J.-C. Liou, S.-Y. Ho, M.-R. Shen, Y.-P. Liao, W.-T. Chiu, and K.-H. Kang
A rapid, nongenomic pathway facilitates the synaptic transmission induced by retinoic acid at the developing synapse
J. Cell Sci., October 15, 2005; 118(20): 4721 - 4730.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
G. Waris and A. Siddiqui
Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication
J. Virol., August 1, 2005; 79(15): 9725 - 9734.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
M. K. Y. Siu, C.-h. Wong, W. M. Lee, and C. Y. Cheng
Sertoli-Germ Cell Anchoring Junction Dynamics in the Testis Are Regulated by an Interplay of Lipid and Protein Kinases
J. Biol. Chem., July 1, 2005; 280(26): 25029 - 25047.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
D. Humphrey, Z. Rajfur, M. E. Vazquez, D. Scheswohl, M. D. Schaller, K. Jacobson, and B. Imperiali
In Situ Photoactivation of a Caged Phosphotyrosine Peptide Derived from Focal Adhesion Kinase Temporarily Halts Lamellar Extension of Single Migrating Tumor Cells
J. Biol. Chem., June 10, 2005; 280(23): 22091 - 22101.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
S. Paruchuri, O. Broom, K. Dib, and A. Sjolander
The Pro-inflammatory Mediator Leukotriene D4 Induces Phosphatidylinositol 3-Kinase and Rac-dependent Migration of Intestinal Epithelial Cells
J. Biol. Chem., April 8, 2005; 280(14): 13538 - 13544.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
N. K. Prasad and S. J. Decker
SH2-containing 5'-Inositol Phosphatase, SHIP2, Regulates Cytoskeleton Organization and Ligand-dependent Down-regulation of the Epidermal Growth Factor Receptor
J. Biol. Chem., April 1, 2005; 280(13): 13129 - 13136.
[Abstract] [Full Text] [PDF]


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J. Immunol.Home page
S. D. Barbee and J. Alberola-Ila
Phosphatidylinositol 3-Kinase Regulates Thymic Exit
J. Immunol., February 1, 2005; 174(3): 1230 - 1238.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
E. Nagata, H. R. Luo, A. Saiardi, B.-I. Bae, N. Suzuki, and S. H. Snyder
Inositol Hexakisphosphate Kinase-2, a Physiologic Mediator of Cell Death
J. Biol. Chem., January 14, 2005; 280(2): 1634 - 1640.
[Abstract] [Full Text] [PDF]


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Mol Cancer ResHome page
K. N. Felekkis, R. P. Narsimhan, R. Near, A. F. Castro, Y. Zheng, L. A. Quilliam, and A. Lerner
AND-34 Activates Phosphatidylinositol 3-Kinase and Induces Anti-Estrogen Resistance in a SH2 and GDP Exchange Factor-Like Domain-Dependent Manner
Mol. Cancer Res., January 1, 2005; 3(1): 32 - 41.
[Abstract] [Full Text] [PDF]


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Mol. Biol. CellHome page
J. H. Seo, Y. Ahn, S.-R. Lee, C. Y. Yeo, and K. C. Hur
The Major Target of the Endogenously Generated Reactive Oxygen Species in Response to Insulin Stimulation Is Phosphatase and Tensin Homolog and Not Phosphoinositide-3 Kinase (PI-3 Kinase) in the PI-3 Kinase/Akt Pathway
Mol. Biol. Cell, January 1, 2005; 16(1): 348 - 357.
[Abstract] [Full Text] [PDF]


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J. Leukoc. Biol.Home page
J. A. Swanson and A. D. Hoppe
The coordination of signaling during Fc receptor-mediated phagocytosis
J. Leukoc. Biol., December 1, 2004; 76(6): 1093 - 1103.
[Abstract] [Full Text] [PDF]


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Am. J. Physiol. Gastrointest. Liver Physiol.Home page
L. Fischer, A. S. Gukovskaya, S. H. Young, I. Gukovsky, A. Lugea, P. Buechler, J. M. Penninger, H. Friess, and S. J. Pandol
Phosphatidylinositol 3-kinase regulates Ca2+ signaling in pancreatic acinar cells through inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase
Am J Physiol Gastrointest Liver Physiol, December 1, 2004; 287(6): G1200 - G1212.
[Abstract] [Full Text] [PDF]


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DevelopmentHome page
I. E. Sasson and M. J. Stern
FGF and PI3 kinase signaling pathways antagonistically modulate sex muscle differentiation in C. elegans
Development, November 1, 2004; 131(21): 5381 - 5392.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
T.-C. Meng, D. A. Buckley, S. Galic, T. Tiganis, and N. K. Tonks
Regulation of Insulin Signaling through Reversible Oxidation of the Protein-tyrosine Phosphatases TC45 and PTP1B
J. Biol. Chem., September 3, 2004; 279(36): 37716 - 37725.
[Abstract] [Full Text] [PDF]


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J. Dent. Res.Home page
G. Spagnuolo, K. Galler, G. Schmalz, C. Cosentino, S. Rengo, and H. Schweikl
Inhibition of Phosphatidylinositol 3-Kinase Amplifies TEGDMA-induced Apoptosis in Primary Human Pulp Cells
J. Dent. Res., September 1, 2004; 83(9): 703 - 707.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
L. S. Agapova, J. L. Volodina, P. M. Chumakov, and B. P. Kopnin
Activation of Ras-Ral Pathway Attenuates p53-independent DNA Damage G2 Checkpoint
J. Biol. Chem., August 27, 2004; 279(35): 36382 - 36389.
[Abstract] [Full Text] [PDF]


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J AndrolHome page
V. Nauc, E. De Lamirande, P. Leclerc, and C. Gagnon
Inhibitors of Phosphoinositide 3-Kinase, LY294002 and Wortmannin, Affect Sperm Capacitation and Associated Phosphorylation of Proteins Differently: Ca2+-Dependent Divergences
J Androl, July 1, 2004; 25(4): 573 - 585.
[Abstract] [Full Text] [PDF]


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J AndrolHome page
P. R. Somanath, S. L. Jack, and S. Vijayaraghavan
Changes in Sperm Glycogen Synthase Kinase-3 Serine Phosphorylation and Activity Accompany Motility Initiation and Stimulation
J Androl, July 1, 2004; 25(4): 605 - 617.
[Abstract] [Full Text] [PDF]


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J. Gen. Virol.Home page
S. Cooray
The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival
J. Gen. Virol., May 1, 2004; 85(5): 1065 - 1076.
[Abstract] [Full Text] [PDF]


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J. Cell Sci.Home page
D. M. Brantley-Sieders, J. Caughron, D. Hicks, A. Pozzi, J. C. Ruiz, and J. Chen
EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation
J. Cell Sci., April 15, 2004; 117(10): 2037 - 2049.
[Abstract] [Full Text] [PDF]


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HypertensionHome page
C. A. Northcott, J. S. Hayflick, and S. W. Watts
PI3-Kinase Upregulation and Involvement in Spontaneous Tone in Arteries From DOCA-Salt Rats: Is p110{delta} the Culprit?
Hypertension, April 1, 2004; 43(4): 885 - 890.
[Abstract] [Full Text] [PDF]


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FASEB J.Home page
Y. KAM and J. H. EXTON
Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid
FASEB J, February 1, 2004; 18(2): 311 - 319.
[Abstract] [Full Text] [PDF]


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J. Neurosci.Home page
M. Tan, M. Groszer, A. M. Tan, A. Pandya, X. Liu, and C.-W. Xie
Phosphoinositide 3-Kinase Cascade Facilitates {micro}-Opioid Desensitization in Sensory Neurons by Altering G-Protein-Effector Interactions
J. Neurosci., November 12, 2003; 23(32): 10292 - 10301.
[Abstract] [Full Text] [PDF]


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Infect. Immun.Home page
S. S. Purushothaman, B. Wang, and P. P. Cleary
M1 Protein Triggers a Phosphoinositide Cascade for Group A Streptococcus Invasion of Epithelial Cells
Infect. Immun., October 1, 2003; 71(10): 5823 - 5830.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
H. R. Luo, H. Hattori, M. A. Hossain, L. Hester, Y. Huang, W. Lee-Kwon, M. Donowitz, E. Nagata, and S. H. Snyder
Akt as a mediator of cell death
PNAS, September 30, 2003; 100(20): 11712 - 11717.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
A. A. Sablina, P. M. Chumakov, and B. P. Kopnin
Tumor Suppressor p53 and Its Homologue p73{alpha} Affect Cell Migration
J. Biol. Chem., July 18, 2003; 278(30): 27362 - 27371.
[Abstract] [Full Text] [PDF]


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Clin. Cancer Res.Home page
W. Wang, J. Hayashi, W. E. Kim, and G. Serrero
PC Cell-derived Growth Factor (Granulin Precursor) Expression and Action in Human Multiple Myeloma
Clin. Cancer Res., June 1, 2003; 9(6): 2221 - 2228.
[Abstract] [Full Text] [PDF]


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J. Neurosci.Home page
P. Opazo, A. M. Watabe, S. G. N. Grant, and T. J. O'Dell
Phosphatidylinositol 3-Kinase Regulates the Induction of Long-Term Potentiation through Extracellular Signal-Related Kinase-Independent Mechanisms
J. Neurosci., May 1, 2003; 23(9): 3679 - 3688.
[Abstract] [Full Text] [PDF]