Cover: The centriolar satellite and centrosome protein CCDC66 directly binds to microtubules and changes their organization when overexpressed in cells. Both CCDC66 and CEP290 are mutated in retinal degeneration, and in cells overexpressing CCDC66 ( purple), CEP290 (cyan) is recruited to the microtubules. Nuclei were visualized using DAPI (yellow). See article by D. Conkar et al. (pp. 1450–1462).