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Journal Articles
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Review – Common signalling pathways in macrophage and osteoclast multinucleation
Macrophage cell fusion and multinucleation are fundamental, yet poorly understood, processes in the formation of multinucleated giant cells (MGC) that underlie various complex diseases. Here, Jacques Behmoaras and colleagues highlight the common pathways involved in osteoclast and MGC fusion.
Cell scientist to watch – Guangshuo Ou
“We should always remind ourselves to move out of our comfort zone and learn something new.”
Guangshuo Ou is a principal investigator of the Joint Center for Life Sciences at Tsinghua and Peking Universities, where his laboratory investigates the mechanisms regulating neural progenitors in C. elegans, using live-imaging, biochemical and genetic tools. Guangshuo became a Journal of Cell Science Editor in 2017. He shares his scientific journey, how to find inspiration in classical literature and why applying a little creativity can add spice to both research protocols and cooking.
We also caught up with early-career first authors María Gabriela Otero, Natalie Farrawell, Oddrun Elise Olsen and Frances Tilley in our First Person interview series.
Cell science at a glance – Plasmodesmata at a glance
This new poster and article from Ross E. Sager and Jung-Youn Lee summarises how plasmodesmata are dynamic and multifaceted nanochannels that bridge neighbouring plant cells.
Review – Integrin activity in neuronal connectivity
Johanna Lilja and Johanna Ivaska provide an overview of the known pathways that are regulated by integrin–ECM interaction in developing neurons and the adult brain. This new Review also describes recent advances in the identification of mechanisms that regulate integrin activity in neurons, and highlights the interesting emerging links between integrins and neurodevelopment.
JCS Meeting – Cell dynamics: organelle-cytoskeleton interface
The second in our series of cell dynamics meetings now turns to organelles. This May 2019 meeting in Lisbon, Portugal, aims to bring together scientists studying the interface between organelles and the cytoskeleton at different scales and perspectives using a range of model systems. Find out more and register your interest here.
preLights – Call for new preLighters
At the heart of preLights is the community of early-career researchers who select and highlight interesting preprints in various fields. We are now ready to grow our team of preLighters who are passionate about preprints and enjoy writing and communicating science. Find out more here and apply by 30 June 2018.
Articles of interest in our sister journals
PI(4,5)P2 forms dynamic cortical structures and directs actin distribution as well as polarity in Caenorhabditis elegans embryos
Melina J. Scholze, Kévin S. Barbieux, Alessandro De Simone, Mathilde Boumasmoud, Camille C. N. Süess, Ruijia Wang, Pierre Gönczy. Development 2018 145: dev164988
Transcriptional induction of cell wall remodelling genes is coupled to microtubule-driven growth isotropy at the shoot apex in Arabidopsis
Alessia Armezzani, Ursula Abad, Olivier Ali, Amélie Andres Robin, Laetitia Vachez, Antoine Larrieu, Ewa J. Mellerowicz, Ludivine Taconnat, Virginie Battu, Massimiliano Sassi et al. Development 2018 145: dev162255