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Ruhee Dere and team have produced an image-based screen using a dual labeling strategy which identifies bexarotene, a rexinoid, as a novel modulator of the primary cilium in VHL-deficient cells. This Research Highlight summarises their Research Article.
Biological experimentation and modeling have advanced our understanding of various cell behaviors. In this review Amy Shaub Maddox and colleagues provide a primer for biologists on several modeling strategies and highlight how modeling has revealed cytokinetic mechanisms.
Glycosphingolipids are emerging as powerful determinants in differentiation events. Here, Domenico Russo and team review the existing literature on the role of glycosphingolipids in cell fate determination.
Have you seen our First Person interviews with the early-career first authors of our papers? The authors talk about their work in and out of the lab, the journeys that led them to where they are now and the scientists who inspired them along the way. Recently, we caught up with first authors Lingling Zhao, Sonam Gurung, Kamil Król and Tomoaki Nagai.
Journal news - New manuscript transfer option
Journal of Cell Science, Journal of Cell Biology and Molecular Biology of the Cell have announced a new manuscript transfer option, which will be available in the first quarter of 2019. It will empower authors whose manuscripts have been declined to seamlessly transfer their manuscripts and associated peer review reports between the journals.
Journal news – New fast-track decision process
Do you have a paper with reviews from another journal that you’d like to submit to Journal of Cell Science? We will fast-track your paper and give you an initial decision within a week. Find out more here.
Maiko Kitaoka highlights a preprint from Peter Lennart and colleagues, which shows F-actin spikes push against the nuclear envelope during cell division in starfish oocyctes to separate nuclear pores and lead to nuclear envelope breakdown.
Catch up with recent preLights selected for the cell science community in our latest Table of Contents.
Articles of interest in our sister journals
The polarity protein VANG-1 antagonizes Wnt signaling by facilitating Frizzled endocytosis
Chun-Wei He, Chien-Po Liao, Chung-Kuan Chen, Jérôme Teulière, Chun-Hao Chen, Chun-Liang Pan
Development 2018 145: dev168666
Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation
Huili Li, Jing Zhang, Lee Niswander
Development 2018 145: dev169797