In this issue

HIF hydroxylases - enzymes for oxygen
J Cell Sci 2003 116: e1501. [Full Text] [PDF]  

A new raft tool
J Cell Sci 2003 116: e1502. [Full Text] [PDF]  

Interferon goes nuclear
J Cell Sci 2003 116: e1503. [Full Text] [PDF]  

Clusterin - an apoptotic puzzle
J Cell Sci 2003 116: e1504. [Full Text] [PDF]  

PI 3-kinases at a glance
J Cell Sci 2003 116: e1505. [Full Text] [PDF]  

Cell Science at a Glance

Fiona M. Foster, Colin J. Traer, Siemon M. Abraham, and Michael J. Fry

The phosphoinositide (PI) 3-kinase family
J Cell Sci 2003 116: 3037-3040. [Full Text] [Figures Only] [PDF]  

Commentaries

Norma Masson and Peter J. Ratcliffe

HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O₂ levels
J Cell Sci 2003 116: 3041-3049. [Summary] [Full Text] [Figures Only] [PDF]  

Giovanni Maga and Ulrich Hübscher

Proliferating cell nuclear antigen (PCNA): a dancer with many partners
J Cell Sci 2003 116: 3051-3060. [Summary] [Full Text] [Figures Only] [PDF]  

Graeme R. Guy, Esther S. M. Wong, Permeen Yusoff, Sumana Chandramouli, Ting Ling Lo, Jormay Lim, and Chee Wai Fong

Sprouty: how does the branch manager work?
J Cell Sci 2003 116: 3061-3068. [Summary] [Full Text] [Figures Only] [PDF]  

Research Articles

Janet K. Jang, Dalia E. Sherizen, Rajal Bhagat, Elizabeth A. Manheim, and Kim S. McKim

Relationship of DNA double-strand breaks to synapsis in Drosophila
J Cell Sci 2003 116: 3069-3077. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00614

Edward T. Parkin, Fulong Tan, Randal A. Skidgel, Anthony J. Turner, and Nigel M. Hooper

The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts
J Cell Sci 2003 116: 3079-3087. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00626

C. M. Iqbal Ahmed, Marjorie A. Burkhart, Mustafa G. Mujtaba, Prem S. Subramaniam, and Howard M. Johnson

The role of IFN nuclear localization sequence in intracellular function
J Cell Sci 2003 116: 3089-3098. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00528

Mónica Álvarez, Xavier Estivill, and Susana de la Luna

DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly
J Cell Sci 2003 116: 3099-3107. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00618

Laure Debure, Jean-Luc Vayssière, Vincent Rincheval, Fabien Loison, Yves Le Dréan, and Denis Michel

Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration
J Cell Sci 2003 116: 3109-3121. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00619

Andrew Smith, Madelon Bracke, Birgit Leitinger, Joanna C. Porter, and Nancy Hogg

LFA-1-induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment
J Cell Sci 2003 116: 3123-3133. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Data]  

First published online on 10 June 2003 as 10.1242/jcs.00606

Ruth Gordon-Weeks, Yiping Tong, T. G. Emyr Davies, and Georg Leggewie

Restricted spatial expression of a high-affinity phosphate transporter in potato roots
J Cell Sci 2003 116: 3135-3144. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00615

Takahisa Takino, Masahito Tamura, Hisashi Miyamori, Masaru Araki, Kazue Matsumoto, Hiroshi Sato, and Kenneth M. Yamada

Tyrosine phosphorylation of the CrkII adaptor protein modulates cell migration
J Cell Sci 2003 116: 3145-3155. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00632

Atsuko Ishizuya-Oka, Katsuhiko Shimizu, Shin-ichi Sakakibara, Hideyuki Okano, and Shuichi Ueda

Thyroid hormone-upregulated expression of Musashi-1 is specific for progenitor cells of the adult epithelium during amphibian gastrointestinal remodeling
J Cell Sci 2003 116: 3157-3164. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00616

Sandra Jurado, José Sánchez-Prieto, and Magdalena Torres

Differential expression of NO-sensitive guanylyl cyclase subunits during the development of rat cerebellar granule cells: regulation via N-methyl-D-aspartate receptors
J Cell Sci 2003 116: 3165-3175. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on 10 June 2003 as 10.1242/jcs.00620

Arun Gidwani, H. Alex Brown, David Holowka, and Barbara Baird

Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FcRI
J Cell Sci 2003 116: 3177-3187. [Summary] [Full Text] [Figures Only] [PDF]  

Valérie Lagrée, Karin Brunschwig, Patricia Lopez, Norton B. Gilula, Gabriele Richard, and Matthias M. Falk

Specific amino-acid residues in the N-terminus and TM3 implicated in channel function and oligomerization compatibility of connexin43
J Cell Sci 2003 116: 3189-3201. [Summary] [Full Text] [Figures Only] [PDF]  

Gertrude-E. Costin, Julio C. Valencia, Wilfred D. Vieira, M. Lynn Lamoreux, and Vincent J. Hearing

Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4
J Cell Sci 2003 116: 3203-3212. [Summary] [Full Text] [Figures Only] [PDF]  

Karen S. Christopherson, Neal T. Sweeney, Sarah E. Craven, Rujun Kang, Alaa El-Din El-Husseini, and David S. Bredt

Lipid- and protein-mediated multimerization of PSD-95: implications for receptor clustering and assembly of synaptic protein networks
J Cell Sci 2003 116: 3213-3219. [Summary] [Full Text] [Figures Only] [PDF]  

Jennifer L. Bankers-Fulbright, Gerald J. Gleich, Gail M. Kephart, Hirohito Kita, and Scott M. O'Grady

Regulation of eosinophil membrane depolarization during NADPH oxidase activation
J Cell Sci 2003 116: 3221-3226. [Summary] [Full Text] [Figures Only] [PDF]  

Ingo Haase, Richard Evans, Ruth Pofahl, and Fiona M. Watt

Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways
J Cell Sci 2003 116: 3227-3238. [Summary] [Full Text] [Figures Only] [PDF]  

Betty C. Gallagher, Kimberly A. Parrott, Gabor Szabo, and Angela de S. Otero

Receptor activation regulates cortical, but not vesicular localization of NDP kinase
J Cell Sci 2003 116: 3239-3250. [Summary] [Full Text] [Figures Only] [PDF]  

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