|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
About the Cover
Cover: Co-transfected plasmids that express different plasmid genes form adjacent transcription domains in the nucleus. Here, plasmids expressing the human 
2-globin gene (red) have been transiently transfected with plasmids expressing the human 
-globin gene (green). The HeLa cell DNA is counterstained with DAPI (blue) and the nascent plasmid RNAs have been labelled by RNA in situ hybridisation using probes to the 2-globin and -globin introns. This effect is only observed when the co-transfected plasmids contain non-homologous gene sequences; plasmids that contain more than 500 bp of homologous gene sequence form shared transcription domains. See article by Binnie et al. (pp._3876-3887).
[Table of Contents]