In this issue

Rho proteins mind the GAPs
J Cell Sci 2008 121: e701. [Full Text] [PDF]  

First published online on March 19, 2008

DC maturation: no place for podosomes
J Cell Sci 2008 121: e702. [Full Text] [PDF]  

First published online on March 19, 2008

Telomerase goes mitochondrial
J Cell Sci 2008 121: e703. [Full Text] [PDF]  

First published online on March 19, 2008

The trials and tubulations of F-BAR proteins
J Cell Sci 2008 121: e704. [Full Text] [PDF]  

First published online on March 19, 2008

MECP2 and chromatin: loose associations
J Cell Sci 2008 121: e705. [Full Text] [PDF]  

First published online on March 19, 2008

Cell Science at a Glance

Cristina de Guzman Strong and Julia A. Segre

Navigating the genome
J Cell Sci 2008 121: 921-923. [Full Text] [Figures Only] [PDF]  

First published online on March 19, 2008 as 10.1242/jcs.022400

Commentary

Christopher Alan Maxwell, James McCarthy, and Eva Turley

Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions?
J Cell Sci 2008 121: 925-932. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on March 19, 2008 as 10.1242/jcs.022038

Short Report

Encarnación Lozano, Marieke A. M. Frasa, Katarzyna Smolarczyk, Ulla G. Knaus, and Vania M. M. Braga

PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac
J Cell Sci 2008 121: 933-938. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 4, 2008 as 10.1242/jcs.016121

Mirna Mourtada-Maarabouni, Vanessa L. Hedge, Lucy Kirkham, Farzin Farzaneh, and Gwyn T. Williams

Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5)
J Cell Sci 2008 121: 939-946. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on March 19, 2008 as 10.1242/jcs.024646

Research Articles

Henning Kessler, Angelika Herm-Götz, Stephan Hegge, Manuel Rauch, Dominique Soldati-Favre, Friedrich Frischknecht, and Markus Meissner

Microneme protein 8 – a new essential invasion factor in Toxoplasma gondii
J Cell Sci 2008 121: 947-956. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 4, 2008 as 10.1242/jcs.022350

Mark L. Cutress, Hayley C. Whitaker, Ian G. Mills, Murray Stewart, and David E. Neal

Structural basis for the nuclear import of the human androgen receptor
J Cell Sci 2008 121: 957-968. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 4, 2008 as 10.1242/jcs.022103

Hanna Sagelius, Ylva Rosengardten, Mubashir Hanif, Michael R. Erdos, Björn Rozell, Francis S. Collins, and Maria Eriksson

Targeted transgenic expression of the mutation causing Hutchinson-Gilford progeria syndrome leads to proliferative and degenerative epidermal disease
J Cell Sci 2008 121: 969-978. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.022913

Subbareddy Maddika, Sudharsana Rao Ande, Emilia Wiechec, Lise Lotte Hansen, Sebastian Wesselborg, and Marek Los

Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
J Cell Sci 2008 121: 979-988. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 19, 2008 as 10.1242/jcs.009530

Wonshill Koh, Rachel D. Mahan, and George E. Davis

Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling
J Cell Sci 2008 121: 989-1001. [Summary] [Full Text] [Figures Only] [PDF]  

First published online on March 4, 2008 as 10.1242/jcs.020693

Mari Inada, Antonia Follenzi, Kang Cheng, Manju Surana, Brigid Joseph, Daniel Benten, Sriram Bandi, Hong Qian, and Sanjeev Gupta

Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation
J Cell Sci 2008 121: 1002-1013. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 4, 2008 as 10.1242/jcs.019315

Chi W. Tang, Apolinar Maya-Mendoza, Catherine Martin, Kang Zeng, Songbi Chen, Dorota Feret, Stuart A. Wilson, and Dean A. Jackson

The integrity of a lamin-B1-dependent nucleoskeleton is a fundamental determinant of RNA synthesis in human cells
J Cell Sci 2008 121: 1014-1024. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.020982

Stephan Busche, Arnaud Descot, Sylvia Julien, Harald Genth, and Guido Posern

Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling
J Cell Sci 2008 121: 1025-1035. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.014456

John F. Alcorn, Amy S. Guala, Jos van der Velden, Brian McElhinney, Charles G. Irvin, Roger J. Davis, and Yvonne M. W. Janssen-Heininger

Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-β1
J Cell Sci 2008 121: 1036-1045. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.019455

Shaheda Ahmed, João F. Passos, Matthew J. Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A. Birch-Machin, Thomas von Zglinicki, and Gabriele Saretzki

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress
J Cell Sci 2008 121: 1046-1053. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.019372

Robert J. W. Heath and Robert H. Insall

Dictyostelium MEGAPs: F-BAR domain proteins that regulate motility and membrane tubulation in contractile vacuoles
J Cell Sci 2008 121: 1054-1064. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.021113

Michael Köhli, Sabrina Buck, and Hans-Peter Schmitz

The function of two closely related Rho proteins is determined by an atypical switch I region
J Cell Sci 2008 121: 1065-1075. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.015933

Ho-Chun Wei, Janet Rollins, Lacramioara Fabian, Madeline Hayes, Gordon Polevoy, Christopher Bazinet, and Julie A. Brill

Depletion of plasma membrane PtdIns(4,5)P₂ reveals essential roles for phosphoinositides in flagellar biogenesis
J Cell Sci 2008 121: 1076-1084. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.024927

Sarah Dunn, Ewan E. Morrison, Tanniemola B. Liverpool, Carmen Molina-París, Robert A. Cross, Maria C. Alonso, and Michelle Peckham

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells
J Cell Sci 2008 121: 1085-1095. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.026492

Suzanne F. G. van Helden, Machteld M. Oud, Ben Joosten, Niels Peterse, Carl G. Figdor, and Frank N. van Leeuwen

PGE₂-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA–Rho-kinase axis
J Cell Sci 2008 121: 1096-1106. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.020289

Yuu Kimata, Akihisa Matsuyama, Koji Nagao, Kanji Furuya, Chikashi Obuse, Minoru Yoshida, and Mitsuhiro Yanagida

Diminishing HDACs by drugs or mutations promotes normal or abnormal sister chromatid separation by affecting APC/C and adherin
J Cell Sci 2008 121: 1107-1118. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 19, 2008 as 10.1242/jcs.024224

Alena Rego, Paul B. Sinclair, Wei Tao, Igor Kireev, and Andrew S. Belmont

The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure
J Cell Sci 2008 121: 1119-1127. [Summary] [Full Text] [Figures Only] [PDF] [Supplementary Material]  

First published online on March 11, 2008 as 10.1242/jcs.026104

Articles of interest in other COB journals

From Development

Masahiro Yamaguchi, Noriko Fujimori-Tonou, Yukihiro Yoshimura, Tsutomu Kishi, Hitoshi Okamoto, and Ichiro Masai

Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53
[Full Text]  

Masayo Shindo, Housei Wada, Masako Kaido, Minoru Tateno, Toshiro Aigaki, Leo Tsuda, and Shigeo Hayashi

Dual function of Src in the maintenance of adherens junctions during tracheal epithelial morphogenesis
[Full Text]  

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