Cryo-electron tomography
- Architecture of the caveolar coat complex
Highlighted Article: This paper reports the first structural analysis of the entire caveolar protein coat isolated intact from mammalian cells, and shows that the coat is composed of two morphologically distinct layers.
- Cellular structural biology as revealed by cryo-electron tomography
Summary: Visualization of macromolecules, organelles and cells by cryo-ET allows for structural analysis in a near-native environment. Recent technological advances have revealed unprecedented structural details.