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Cryo-electron tomography

  • SHORT REPORT
    Architecture of the caveolar coat complex
    Alexander Ludwig, Benjamin James Nichols, Sara Sandin
    J Cell Sci 2016 129: 3077-3083; doi: 10.1242/jcs.191262

    Highlighted Article: This paper reports the first structural analysis of the entire caveolar protein coat isolated intact from mammalian cells, and shows that the coat is composed of two morphologically distinct layers.

  • COMMENTARY
    Cellular structural biology as revealed by cryo-electron tomography
    Rossitza N. Irobalieva, Bruno Martins, Ohad Medalia
    J Cell Sci 2016 129: 469-476; doi: 10.1242/jcs.171967

    Summary: Visualization of macromolecules, organelles and cells by cryo-ET allows for structural analysis in a near-native environment. Recent technological advances have revealed unprecedented structural details.

  • RESEARCH ARTICLE
    The role of integrin-linked kinase in the molecular architecture of focal adhesions
    Nadav Elad, Tova Volberg, Israel Patla, Vera Hirschfeld-Warneken, Carsten Grashoff, Joachim P. Spatz, Reinhard Fässler, Benjamin Geiger, Ohad Medalia
    J Cell Sci 2013 126: 4099-4107; doi: 10.1242/jcs.120295

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