Flagellum attachment zone
- Flagellar pocket restructuring through the Leishmania life cycle involves a discrete flagellum attachment zone
Summary: Leishmania parasites have a highly structured flagellar pocket, including a structure homologous to the Trypanosoma brucei flagellum attachment zone, which undergoes structural adaptations in different life cycle stages.
- Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions
Summary: Trypanosoma brucei FLAM3 is a flagellar FAZ protein. Its depletion leads to a reduction in FAZ length, which has different consequences depending on the life cycle stage of the parasite.
- Assembly and maintenance of the flagellum attachment zone filament in Trypanosoma brucei
Highlighted Article: Three new T. brucei flagellum attachment zone filament proteins are identified, and it is shown that assembly of the filament occurs at the proximal base and is essential for filament protein stability.