- Kon-tiki enhances PS2 integrin adhesion and localizes its ligand, Thrombospondin, in the myotendinous junction
Summary: The Drosophila proteoglycan Kon-tiki/Perdido enhances αPS2βPS integrin adhesion and localizes its ligand, Thrombospondin. This would lead to increased integrin adhesion to the ECM, and consolidation of the muscle–tendon junction.
- The NF-κB-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes
Summary: miR-195 and miR-497 are negatively regulated by the myogenic factor NF-κB, and they could inhibit myoblast proliferation through targeting the Igf1r, Insr and cyclin genes.