In This Issue
Cell Science at a Glance
Research Articles
This issue
Other journals from The Company of Biologists
JCS Prize 2018 Winner: Samantha Stehbens
We are pleased to announce that the winner of the 2018 JCS Prize is Samantha Stehbens for her paper entitled ‘FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer’. The $1000 prize is awarded annually to the first author of the paper that is judged to be the best by the Editors and Editorial Board.
Review - CORVET, CHEVI and HOPS – multisubunit tethers of the endo-lysosomal system in health and disease 
CORVET, CHEVI and HOPS are multisubunit tethering complexes that regulate the major membrane flows required for endocytosis, lysosome biogenesis, autophagy and phagocytosis. Judith Klumperman and colleagues provide an integrated overview on the cellular functions of these proteins and pathological defects associated with them.
Review - Regulation of Cdc42 and its effectors in epithelial morphogenesis
The small Rho GTPase family member Cdc42 regulates cell polarity across organisms. Franck Pichaud, Rhian Walther and Francisca Nunes de Almeida review how the spatial regulation of Cdc42 promotes polarity and polarized morphogenesis of the plasma membrane, with a focus on the epithelial cell type.
Mole - The gift
“If someone shares an idea with you, they are sharing something they created, or if not, something they obtained and feel has value.”
Mole explains why we should receive ideas as gifts.
First Person interviews
Have you seen our First Person interviews with the early-career first authors of our papers? The authors talk about their work in and out of the lab, the journeys that led them to where they are now and the scientists who inspired them along the way. Recently, we caught up with first authors Samantha Salvage, Yasuha Kinugasa and Abhishek Chadha.
Journal of Cell Science (JCS), Journal of Cell Biology (JCB) and Molecular Biology of the Cell (MBoC) announce a new manuscript transfer option that will empower authors whose manuscripts have been declined to seamlessly transfer their manuscripts and associated peer review reports between the journals.
Travelling Fellowships – Expanded understanding of leukaemia treatment
We offer Travelling Fellowships of up to £2,500 to graduate students and post-doctoral researchers wishing to make collaborative visits to other laboratories. The next deadline to apply is 31 May 2019.
Alexander García Ponce used a Travelling Fellowship to go to the Sanquin Blood Bank in The Netherlands. There he investigated how hematopoietic stem cells cross the vascular wall and reach the bone marrow for his PhD project.
Journal of Cell Science is pleased to welcome submissions for an upcoming special issue on 'Cell Biology of the Immune System' edited by Ana-Maria Lennon-Duménil. We invite you to showcase your breakthrough research on all aspects of cell biology as it relates to the immune system. The articles within this issue will receive extensive exposure to a broad audience of cell biologists and immunologists. Submission deadline: 30 June 2019.
preLights - Actin chromobody imaging reveals sub-organellar actin dynamics
Mariana De Niz highlights a preprint from Uri Manor and colleagues who use nanobody technology for live imaging of sub-organellar actin dynamics at previously unachieved temporal and spatial resolution, and explore its relevance for organelle fission.
Catch up with other recent preLights selected for the cell science community.
Articles of interest in our sister journals
A single KH domain in Bicaudal-C links mRNA binding and translational repression functions to maternal development
Megan E. Dowdle, Sookhee Park, Susanne Blaser Imboden, Catherine A. Fox, Douglas W. Houston, Michael D. Sheets
Development 2019 146: dev172486
Primary wall cellulose synthase regulates shoot apical meristem mechanics and growth
Arun Sampathkumar, Alexis Peaucelle, Miki Fujita, Christoph Schuster, Staffan Persson, Geoffrey O. Wasteneys, Elliot M. Meyerowitz
Development 2019 146: dev179036