Cover image

Cover: 3D representation of spreading NIH3T3 cells with or without knockdown of Crk-family proteins. Shown are images of a wild-type NIH3T3 cell (left) and of one that expressed shRNA targeting all Crk family proteins (right). Cells were immunostained using antibody against vinculin (green), and F-actin was visualized with Texas-Red-conjugated phalloidin (red) (top and middle, respectively). The merged image is shown at the bottom. Red and green rectangular sub-panels represent x-z and y-z axes of the cell images. See article by S. Antoku et al. (p. 3071).