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Commentary
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
Ciaran Richardson, Dario R. Alessi
Journal of Cell Science 2008 121: 3293-3304; doi: 10.1242/jcs.029223
Ciaran Richardson
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Dario R. Alessi
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Article Information

vol. 121 no. 20, 3293-3304

DOI 
https://doi.org/10.1242/jcs.029223
PubMed 
18843116

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Accepted August 19, 2008
  • Published online October 8, 2008.
Copyright & Usage 
© The Company of Biologists Limited 2008


Author Information

  1. Ciaran Richardson
  1. MRC Protein Phosphorylation Unit, Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
  1. Dario R. Alessi
  1. MRC Protein Phosphorylation Unit, Sir James Black Centre, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
  1. e-mail: c.j.z.richardson{at}dundee.ac.uk
  2. e-mail: d.r.alessi{at}dundee.ac.uk

Article usage

Usage statistics are calculated at the beginning of each month for the previous month.

Usage statistics: October 2008 to March 2021

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Mar 2009326254
Apr 2009189878
May 20091410887
Jun 20091010883
Jul 2009128167
Aug 2009167563
Sep 2009188275
Oct 200918117101
Nov 20092413174
Dec 2009197563
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Feb 2010307057
Mar 2010218663
Apr 20102410460
May 2010508151
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Jul 2010337842
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Feb 2011126647
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Apr 2011107245
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Jul 2011455940
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Total350294405296

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Commentary
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
Ciaran Richardson, Dario R. Alessi
Journal of Cell Science 2008 121: 3293-3304; doi: 10.1242/jcs.029223
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Commentary
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
Ciaran Richardson, Dario R. Alessi
Journal of Cell Science 2008 121: 3293-3304; doi: 10.1242/jcs.029223

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Article navigation

  • Top
  • Article
    • Summary
    • Introduction
    • Key features of WNK isoforms
    • Regulation of WNK isoforms
    • The interaction of SPAK and OSR1 with WNK isoforms
    • Regulation of SLC12 family members by WNK-SPAK/OSR1 signalling
    • Genetic analysis of the WNK signalling pathway
    • SPAK and OSR1 – new drug targets for the treatment of hypertension?
    • Other WNK-regulated pathways
    • Conclusions and perspectives
    • Acknowledgements
    • References
  • Figures & tables
  • Info & metrics
  • PDF

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