Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Interviews
    • Sign up for alerts
  • About us
    • About JCS
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Fast-track manuscripts
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • JCS Prize
    • Manuscript transfer network
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact the journal
    • Subscriptions
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Journal of Cell Science
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Journal of Cell Science

  • Log in
Advanced search

RSS   Twitter  Facebook   YouTube  

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Interviews
    • Sign up for alerts
  • About us
    • About JCS
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Fast-track manuscripts
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • JCS Prize
    • Manuscript transfer network
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact the journal
    • Subscriptions
    • Advertising
    • Feedback
Research Article
Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death
Kuei-Hua Chang, Fabien Vincent, Kavita Shah
Journal of Cell Science 2012 125: 5124-5137; doi: 10.1242/jcs.108183
Kuei-Hua Chang
Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fabien Vincent
Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kavita Shah
Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: shah23@purdue.edu
  • Article
  • Figures & tables
  • Info & metrics
  • PDF
Loading

Article Information

vol. 125 no. 21, 5124-5137

DOI 
https://doi.org/10.1242/jcs.108183
PubMed 
22899714

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Accepted July 5, 2012
  • Published online December 31, 2012.
Posted online 
August 16, 2012
Copyright & Usage 
© 2012. Published by The Company of Biologists Ltd

Article Versions

  • Previous version (August 16, 2012 - 01:09).
  • You are viewing the most recent version of this article.

Author Information

  1. Kuei-Hua Chang,
  2. Fabien Vincent and
  3. Kavita Shah*
  1. Department of Chemistry and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA
  1. ↵*Author for correspondence (shah23{at}purdue.edu)
View Abstract

Article usage

Usage statistics are calculated at the beginning of each month for the previous month.

Usage statistics: August 2012 to November 2019

AbstractFullPdf
Aug 2012322085
Sep 2012101071
Oct 201236035
Nov 201234030
Dec 201278017
Total 20125710238
Jan 20138353454
Feb 20131111820
Mar 2013521522
Apr 2013731518
May 2013364134
Jun 2013293024
Jul 2013343023
Aug 2013183125
Sep 2013126029
Oct 2013182535
Nov 2013223524
Dec 2013492322
Total 20131289357330
Jan 2014292517
Feb 2014182016
Mar 2014252523
Apr 2014191028
May 2014364043
Jun 2014132619
Jul 2014202124
Aug 201491436
Sep 2014162029
Oct 2014133223
Nov 2014142325
Dec 2014172528
Total 2014229281311
Jan 2015121117
Feb 2015211215
Mar 201592621
Apr 201591752
May 2015151425
Jun 201512199
Jul 201581722
Aug 2015101116
Sep 2015162940
Oct 201581826
Nov 201561644
Dec 201552513
Total 2015131215300
Jan 2016233527
Feb 20161034159
Mar 2016205934
Apr 201692819
May 2016133435
Jun 2016142435
Jul 201694719
Aug 201662916
Sep 201672520
Oct 201673623
Nov 201642617
Dec 201654016
Total 2016127417420
Jan 201722017
Feb 201733326
Mar 201743123
Apr 201702418
May 201722437
Jun 201713516
Jul 201731817
Aug 201701829
Sep 201722636
Oct 201712119
Nov 201702520
Dec 20171218
Total 201719296266
Jan 20180296
Feb 201812216
Mar 201813722
Apr 201803419
May 20182268
Jun 20181174
Jul 20182189
Aug 20180155
Sep 20181247
Oct 20183209
Nov 201801915
Dec 20181149
Total 201812275129
Jan 201911815
Feb 201931612
Mar 201932617
Apr 201921515
May 201921412
Jun 201901311
Jul 201911110
Aug 201911310
Sep 2019186
Oct 201916014
Nov 20191158
Total 201916209130
Total239420502124

Statistics from Altmetric.com

Previous ArticleNext Article
Back to top
Previous ArticleNext Article

This Issue

Keywords

  • Chemical genetic screen
  • Cdk5
  • cdc25
  • Alzheimer’s disease

 Download PDF

Email

Thank you for your interest in spreading the word on Journal of Cell Science.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death
(Your Name) has sent you a message from Journal of Cell Science
(Your Name) thought you would like to see the Journal of Cell Science web site.
Share
Research Article
Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death
Kuei-Hua Chang, Fabien Vincent, Kavita Shah
Journal of Cell Science 2012 125: 5124-5137; doi: 10.1242/jcs.108183
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Research Article
Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death
Kuei-Hua Chang, Fabien Vincent, Kavita Shah
Journal of Cell Science 2012 125: 5124-5137; doi: 10.1242/jcs.108183

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Alerts

Please log in to add an alert for this article.

Sign in to email alerts with your email address

Article navigation

  • Top
  • Article
    • Summary
    • Introduction
    • Results
    • Discussion
    • Materials and Methods
    • Footnotes
    • References
  • Figures & tables
  • Info & metrics
  • PDF

Related articles

Cited by...

More in this TOC section

  • Epidermal growth factor receptor signaling suppresses αvβ6 integrin and promotes periodontal inflammation and bone loss
  • IL-15Rα membrane anchorage in either cis or trans is required for stabilization of IL-15 and optimal signaling
  • A novel interplay between GEFs orchestrates Cdc42 activity during cell polarity and cytokinesis in fission yeast
Show more RESEARCH ARTICLE

Similar articles

Other journals from The Company of Biologists

Development

Journal of Experimental Biology

Disease Models & Mechanisms

Biology Open

Advertisement

First Person interviews

Photo collage of Chen Yu, Sushmita Chatterjee, Ruiqi Wang and Lotte Vanheer.

Have you seen our First Person interviews with the early-career first authors of our papers? The authors talk about their work in and out of the lab, the journeys that led them to where they are now and the scientists who inspired them along the way. Recently, we caught up with first authors Maitreyi Rathod, Sushmita Chatterjee, Lotte Vanheer, Rachel Furlong, Pamela Adami, Ruiqi Wang and Chen Yu.


Travelling Fellowship – New imaging approach unveils a bigger picture

Highlights from Travelling Fellowship trips

Find out how Pamela Imperadore’s Travelling Fellowship grant from The Company of Biologists took her to Germany, where she used new imaging techniques to investigate the cellular machinery underlying octopus arm regeneration. Don’t miss the next application deadline for 2020 travel, coming up on 29 November. Where will your research take you?


preLights – Meet the preLighters: an interview with Maiko Kitaoka

Maiko Kitaoka

Maiko Kitaoka is a graduate student in the lab of Rebecca Heald at the University of California, Berkeley. Here she studies the cause of chromosome mis-segregation defects in Xenopus hybrids. We caught up with Maiko to discuss her research, science communication, ballet, preprints and more.


Journal Meeting – Cell Dynamics: Host-Pathogen Interface

Registration is now open for the third instalment of the highly successful Cellular Dynamics Meeting Series, and will focus on ‘Host-Pathogen Interface’. The meeting will take place 17-20 May 2020, and further information is available here.


Cell Science at a Glance – Adaptor protein complexes and disease at a glance

A new poster from the Robinson lab summarises what is known about the five adaptor protein complexes and discuss how this helps to explain the clinical features of different genetic disorders.


JCS joins the Review Commons initiative

Journal of Cell Science is pleased to be a part of the new and exciting Review Commons initiative, launched by EMBO and ASAPbio. Streamlining the publishing process, Review Commons enables high-quality peer review to take place before journal submission. Papers submitted to Review Commons will be assessed independently of any journal, focusing solely on the paper’s scientific rigor and merit.


Articles of interest in our sister journals

Casein kinase 1α decreases β-catenin levels at adherens junctions to facilitate wound closure in Drosophila larvae
Chang-Ru Tsai, Michael J. Galko
Development

Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis
Elizabeth Vargas, Karen P. McNally, Daniel B. Cortes, Michelle T. Panzica, Brennan M. Danlasky, Qianyan Li, Amy Shaub Maddox, Francis J. McNally
Development

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Special issues
  • Subject collections
  • Interviews
  • Sign up for alerts

About us

  • About Journal of Cell Science
  • Editors and Board
  • Editor biographies
  • Travelling Fellowships
  • Grants and funding
  • Journal Meetings
  • Workshops
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Fast-track manuscripts
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • JCS Prize
  • Manuscript transfer network
  • Biology Open transfer

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact Journal of Cell Science
  • Subscriptions
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2019   The Company of Biologists Ltd   Registered Charity 277992