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Research Article
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
Krista Rantanen, Juha-Pekka Pursiheimo, Heidi Högel, Petra Miikkulainen, Jari Sundström, Panu M. Jaakkola
Journal of Cell Science 2013 126: 1144-1154; doi: 10.1242/jcs.115667
Krista Rantanen
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Juha-Pekka Pursiheimo
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Heidi Högel
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Petra Miikkulainen
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Jari Sundström
2Department of Pathology, Turku University Hospital, Turku, Finland
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Panu M. Jaakkola
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
3Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland
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  • For correspondence: panjaa@utu.fi
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Article Information

vol. 126 no. 5, 1144-1154

DOI 
https://doi.org/10.1242/jcs.115667
PubMed 
23345396

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Accepted December 14, 2012
  • Published online April 25, 2013.
Posted online 
January 23, 2013
Copyright & Usage 
© 2013. Published by The Company of Biologists Ltd

Article Versions

  • Previous version (January 23, 2013 - 06:46).
  • You are viewing the most recent version of this article.

Author Information

  1. Krista Rantanen1,*,
  2. Juha-Pekka Pursiheimo1,*,
  3. Heidi Högel1,
  4. Petra Miikkulainen1,
  5. Jari Sundström2 and
  6. Panu M. Jaakkola1,3,‡
  1. 1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
  2. 2Department of Pathology, Turku University Hospital, Turku, Finland
  3. 3Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland
  1. ↵‡Author for correspondence (panjaa{at}utu.fi)
  1. ↵* These authors contributed equally to this work

Article usage

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Sep 202051811
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Total 202040230199
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Feb 202163417
Total 2021135944
Total227726103812

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Keywords

  • Autophagy
  • Aggresome
  • HIF
  • Hypoxia
  • LC-3
  • LIR domain
  • NBR1
  • Prolyl hydroxylase
  • pVHL
  • Sequestosome1

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Research Article
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
Krista Rantanen, Juha-Pekka Pursiheimo, Heidi Högel, Petra Miikkulainen, Jari Sundström, Panu M. Jaakkola
Journal of Cell Science 2013 126: 1144-1154; doi: 10.1242/jcs.115667
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Research Article
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
Krista Rantanen, Juha-Pekka Pursiheimo, Heidi Högel, Petra Miikkulainen, Jari Sundström, Panu M. Jaakkola
Journal of Cell Science 2013 126: 1144-1154; doi: 10.1242/jcs.115667

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