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Research Article
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
Krista Rantanen, Juha-Pekka Pursiheimo, Heidi Högel, Petra Miikkulainen, Jari Sundström, Panu M. Jaakkola
Journal of Cell Science 2013 126: 1144-1154; doi: 10.1242/jcs.115667
Krista Rantanen
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Juha-Pekka Pursiheimo
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Heidi Högel
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Petra Miikkulainen
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
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Jari Sundström
2Department of Pathology, Turku University Hospital, Turku, Finland
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Panu M. Jaakkola
1Turku Centre for Biotechnology, Turku University and Åbo Akademi University, Turku, Finland
3Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland
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  • For correspondence: panjaa@utu.fi
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Keywords

  • Autophagy
  • Aggresome
  • HIF
  • Hypoxia
  • LC-3
  • LIR domain
  • NBR1
  • Prolyl hydroxylase
  • pVHL
  • Sequestosome1

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Research Article
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
Krista Rantanen, Juha-Pekka Pursiheimo, Heidi Högel, Petra Miikkulainen, Jari Sundström, Panu M. Jaakkola
Journal of Cell Science 2013 126: 1144-1154; doi: 10.1242/jcs.115667
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Research Article
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
Krista Rantanen, Juha-Pekka Pursiheimo, Heidi Högel, Petra Miikkulainen, Jari Sundström, Panu M. Jaakkola
Journal of Cell Science 2013 126: 1144-1154; doi: 10.1242/jcs.115667

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