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Research Article
4-hydroxytamoxifen leads to PrPSc clearance by conveying both PrPC and PrPSc to lysosomes independently of autophagy
Ludovica Marzo, Zrinka Marijanovic, Duncan Browman, Zeina Chamoun, Anna Caputo, Chiara Zurzolo
Journal of Cell Science 2013 126: 1345-1354; doi: 10.1242/jcs.114801
Ludovica Marzo
1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
2Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli ‘Federico II’, Via Pansini 5, 80131 Napoli, Italy
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Zrinka Marijanovic
1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
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Duncan Browman
1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
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Zeina Chamoun
1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
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Anna Caputo
1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
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Chiara Zurzolo
1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
2Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli ‘Federico II’, Via Pansini 5, 80131 Napoli, Italy
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  • For correspondence: chiara.zurzolo@pasteur.fr
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Article Information

vol. 126 no. 6, 1345-1354

DOI 
https://doi.org/10.1242/jcs.114801
PubMed 
23418355

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Accepted January 2, 2013
  • Published online May 4, 2013.
Posted online 
February 15, 2013
Copyright & Usage 
© 2013. Published by The Company of Biologists Ltd

Article Versions

  • Previous version (February 15, 2013 - 05:56).
  • You are viewing the most recent version of this article.

Author Information

  1. Ludovica Marzo1,2,*,
  2. Zrinka Marijanovic1,*,
  3. Duncan Browman1,
  4. Zeina Chamoun1,
  5. Anna Caputo1 and
  6. Chiara Zurzolo1,2,‡
  1. 1Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25 rue du Docteur Roux, 75015 Paris, France
  2. 2Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli ‘Federico II’, Via Pansini 5, 80131 Napoli, Italy
  1. ↵‡Author for correspondence (chiara.zurzolo{at}pasteur.fr)
  1. ↵* These authors contributed equally to this work

Article usage

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Usage statistics: February 2013 to January 2021

AbstractFullPdf
Feb 2013226191
Mar 2013117038
Apr 201362062
May 20134121728
Jun 2013994039
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Aug 2013304430
Sep 2013272616
Oct 2013223227
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Jul 20142721617
Aug 2014317414
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Mar 201627011
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May 20163887
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Jul 201666144
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Mar 20171759
Apr 20170857
May 20174803
Jun 20171947
Jul 20171616
Aug 201765014
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Feb 20187288
Mar 201873111
Apr 20185321
May 20182476
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Aug 20181335
Sep 20185215
Oct 20185274
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Mar 20191139
Apr 20198195
May 20197217
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Feb 202072410
Mar 20203144
Apr 20201148
May 20205226
Jun 20206267
Jul 20205218
Aug 202031111
Sep 2020354
Oct 202054922
Nov 202021915
Dec 20202226
Total 202049240107
Jan 202111510
Total 202111510
Total188857341316

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Keywords

  • PrPSc
  • TAM
  • OHT
  • Autophagy
  • Lysosomal degradation
  • Cholesterol

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Research Article
4-hydroxytamoxifen leads to PrPSc clearance by conveying both PrPC and PrPSc to lysosomes independently of autophagy
Ludovica Marzo, Zrinka Marijanovic, Duncan Browman, Zeina Chamoun, Anna Caputo, Chiara Zurzolo
Journal of Cell Science 2013 126: 1345-1354; doi: 10.1242/jcs.114801
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Research Article
4-hydroxytamoxifen leads to PrPSc clearance by conveying both PrPC and PrPSc to lysosomes independently of autophagy
Ludovica Marzo, Zrinka Marijanovic, Duncan Browman, Zeina Chamoun, Anna Caputo, Chiara Zurzolo
Journal of Cell Science 2013 126: 1345-1354; doi: 10.1242/jcs.114801

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