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February, 2014; 127 (3)

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Cover: Chains of postnatal mouse neuroblasts extend out of rostral migratory stream explants embedded in Matrigel. Cells are immunostained for the neuroblast marker βIII tubulin (red). F-actin is visualized by fluorescent phalloidin (green) and nuclei by Hoechst 33342 (blue). The polarized migration of stem-cell-derived neuroblasts is a fundamental aspect in postnatal neurogenesis, influencing the final differentiation of these cells into mature neurons. The small Ras-like GTPase RalA regulates neuroblast morphology and polarity in vivo by promoting a direct interaction between Exo84, a subunit of the exocyst, and Par6, a component of the Par complex. See article by A. Das et al. (pp. 686–699).

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Journal of Cell Science: 127 (3)
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