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Commentary
GSK-3 – at the crossroads of cell death and survival
Ulrich Maurer, Florian Preiss, Prisca Brauns-Schubert, Lisa Schlicher, Céline Charvet
Journal of Cell Science 2014 127: 1369-1378; doi: 10.1242/jcs.138057
Ulrich Maurer
Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Stefan Meier Strasse 17, 79104 Freiburg, GermanySpemann Graduate School for Biology and Medicine (SGBM), Albert-Ludwigs-University Freiburg, Albertstrasse 19a, 79104 Freiburg, GermanyBIOSS, Centre for Biological Signaling Studies, Hebelstrasse 2, 79104 Freiburg, Germany
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  • For correspondence: ulrich.maurer@mol-med.uni-freiburg.de
Florian Preiss
Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Stefan Meier Strasse 17, 79104 Freiburg, GermanySpemann Graduate School for Biology and Medicine (SGBM), Albert-Ludwigs-University Freiburg, Albertstrasse 19a, 79104 Freiburg, GermanyFaculty of Biology, Albert-Ludwigs-University Freiburg, Schänzlestrasse 1, Freiburg, Germany
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Prisca Brauns-Schubert
Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Stefan Meier Strasse 17, 79104 Freiburg, GermanySpemann Graduate School for Biology and Medicine (SGBM), Albert-Ludwigs-University Freiburg, Albertstrasse 19a, 79104 Freiburg, GermanyFaculty of Biology, Albert-Ludwigs-University Freiburg, Schänzlestrasse 1, Freiburg, Germany
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Lisa Schlicher
Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Stefan Meier Strasse 17, 79104 Freiburg, GermanySpemann Graduate School for Biology and Medicine (SGBM), Albert-Ludwigs-University Freiburg, Albertstrasse 19a, 79104 Freiburg, GermanyBIOSS, Centre for Biological Signaling Studies, Hebelstrasse 2, 79104 Freiburg, GermanyFaculty of Biology, Albert-Ludwigs-University Freiburg, Schänzlestrasse 1, Freiburg, Germany
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Céline Charvet
Inserm, U1016, Institut Cochin, Paris, FranceCNRS, UMR8104, Paris, FranceUniv Paris Descartes, Paris, France
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Article Information

vol. 127 no. 7, 1369-1378

DOI 
https://doi.org/10.1242/jcs.138057
PubMed 
24687186

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Received November 6, 2013
  • Accepted February 13, 2014
  • Published online March 31, 2014.
Copyright & Usage 
© 2014. Published by The Company of Biologists Ltd


Author Information

  1. Ulrich Maurer1,2,3,*,
  2. Florian Preiss1,2,4,
  3. Prisca Brauns-Schubert1,2,4,
  4. Lisa Schlicher1,2,3,4 and
  5. Céline Charvet5,6,7
  1. 1Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Stefan Meier Strasse 17, 79104 Freiburg, Germany
  2. 2Spemann Graduate School for Biology and Medicine (SGBM), Albert-Ludwigs-University Freiburg, Albertstrasse 19a, 79104 Freiburg, Germany
  3. 3BIOSS, Centre for Biological Signaling Studies, Hebelstrasse 2, 79104 Freiburg, Germany
  4. 4Faculty of Biology, Albert-Ludwigs-University Freiburg, Schänzlestrasse 1, Freiburg, Germany
  5. 5Inserm, U1016, Institut Cochin, Paris, France
  6. 6CNRS, UMR8104, Paris, France
  7. 7Univ Paris Descartes, Paris, France
  1. ↵*Author for correspondence (ulrich.maurer{at}mol-med.uni-freiburg.de)
View Abstract

Article usage

Usage statistics are calculated at the beginning of each month for the previous month.

Usage statistics: March 2014 to November 2019

AbstractFullPdf
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Total 20191242706618
Total241582642961

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Keywords

  • Glycogen synthase kinase 3
  • GSK-3
  • Phosphoinositide 3-kinase
  • PI3K
  • Apoptosis

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Commentary
GSK-3 – at the crossroads of cell death and survival
Ulrich Maurer, Florian Preiss, Prisca Brauns-Schubert, Lisa Schlicher, Céline Charvet
Journal of Cell Science 2014 127: 1369-1378; doi: 10.1242/jcs.138057
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Commentary
GSK-3 – at the crossroads of cell death and survival
Ulrich Maurer, Florian Preiss, Prisca Brauns-Schubert, Lisa Schlicher, Céline Charvet
Journal of Cell Science 2014 127: 1369-1378; doi: 10.1242/jcs.138057

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  • Top
  • Article
    • ABSTRACT
    • Introduction
    • GSK-3 is inactivated by kinase signaling pathways
    • Inactivation of GSK-3 in protein complexes
    • GSK-3 and the regulation of cell death
    • GSK-3 controls the activity of Bcl-2 family proteins
    • GSK-3 promotes p53-mediated apoptosis
    • GSK-3 as a mediator of cell survival
    • Conclusions
    • Footnotes
    • References
  • Figures & tables
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