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OPINION
Decoding the stem cell quiescence cycle – lessons from yeast for regenerative biology
Jyotsna Dhawan, Sunil Laxman
Journal of Cell Science 2015 128: 4467-4474; doi: 10.1242/jcs.177758
Jyotsna Dhawan
1Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India
2CSIR Center for Cellular and Molecular Biology, Hyderabad, India
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  • For correspondence: jdhawan@instem.res.in sunil@instem.res.in
Sunil Laxman
1Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India
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  • For correspondence: jdhawan@instem.res.in sunil@instem.res.in
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Article Information

vol. 128 no. 24, 4467-4474

DOI 
https://doi.org/10.1242/jcs.177758
PubMed 
26672015

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Published online December 15, 2015.
Copyright & Usage 
© 2015. Published by The Company of Biologists Ltd


Author Information

  1. Jyotsna Dhawan1,2,* and
  2. Sunil Laxman1,*
  1. 1Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India
  2. 2CSIR Center for Cellular and Molecular Biology, Hyderabad, India
  1. ↵*Authors for correspondence (jdhawan{at}instem.res.in; sunil{at}instem.res.in)
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Total167341111674

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Keywords

  • Quiescence
  • Metabolism
  • Yeast
  • Adult stem cell
  • Signaling pathways
  • Regeneration

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OPINION
Decoding the stem cell quiescence cycle – lessons from yeast for regenerative biology
Jyotsna Dhawan, Sunil Laxman
Journal of Cell Science 2015 128: 4467-4474; doi: 10.1242/jcs.177758
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OPINION
Decoding the stem cell quiescence cycle – lessons from yeast for regenerative biology
Jyotsna Dhawan, Sunil Laxman
Journal of Cell Science 2015 128: 4467-4474; doi: 10.1242/jcs.177758

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Article navigation

  • Top
  • Article
    • ABSTRACT
    • Introduction
    • The concept of a ‘quiescence cycle’
    • Distinct states of quiescence exist
    • Metabolic states, heterogeneity and quiescence
    • Signaling pathways in quiescence – from yeast to stem cells
    • Stages of awakening of quiescent cells
    • Circulating factors and stem cell dormancy – the hope of rejuvenation
    • Therapeutic opportunities – identifying candidates to control stem cell function using yeast
    • Perspectives – yeast biology and regenerative medicine
    • Acknowledgements
    • Footnotes
    • References
  • Figures & tables
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  • PDF

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