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Research Article
IQGAP1 controls tight junction formation through differential regulation of claudin recruitment
Barbara E. Tanos, Andres E. Perez Bay, Susana Salvarezza, Igor Vivanco, Ingo Mellinghoff, Mahasin Osman, David B. Sacks, Enrique Rodriguez-Boulan
Journal of Cell Science 2015 128: 853-862; doi: 10.1242/jcs.118703
Barbara E. Tanos
1Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA
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  • For correspondence: Barbara.tanos@icr.ac.uk Boulan@med.cornell.edu
Andres E. Perez Bay
1Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA
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Susana Salvarezza
1Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA
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Igor Vivanco
2Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
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Ingo Mellinghoff
2Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
3Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA
4Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
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Mahasin Osman
5Department of Molecular Pharmacology, Physiology and Biotechnology, Division of Biology and Medicine, Alpert School of Medicine, Brown University, Providence, RI 02912, USA
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David B. Sacks
6Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892, USA
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Enrique Rodriguez-Boulan
1Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA
7Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA
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  • For correspondence: Barbara.tanos@icr.ac.uk Boulan@med.cornell.edu
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Article Information

vol. 128 no. 5, 853-862

DOI 
https://doi.org/10.1242/jcs.118703
PubMed 
25588839

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Received August 24, 2012
  • Accepted November 5, 2014
  • Published online February 27, 2015.
Posted online 
January 14, 2015
Copyright & Usage 
© 2015. Published by The Company of Biologists Ltd

Article Versions

  • Previous version (January 14, 2015 - 05:07).
  • You are viewing the most recent version of this article.

Author Information

  1. Barbara E. Tanos1,*,‡§,
  2. Andres E. Perez Bay1,‡,
  3. Susana Salvarezza1,
  4. Igor Vivanco2,*,
  5. Ingo Mellinghoff2,3,4,
  6. Mahasin Osman5,
  7. David B. Sacks6 and
  8. Enrique Rodriguez-Boulan1,7,§
  1. 1Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA
  2. 2Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA
  3. 3Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA
  4. 4Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
  5. 5Department of Molecular Pharmacology, Physiology and Biotechnology, Division of Biology and Medicine, Alpert School of Medicine, Brown University, Providence, RI 02912, USA
  6. 6Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892, USA
  7. 7Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA
  1. ↵§Authors for correspondence (Barbara.tanos{at}icr.ac.uk; Boulan{at}med.cornell.edu)

Article usage

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Usage statistics: January 2015 to January 2021

AbstractFullPdf
Jan 20153240133
Feb 20152631469
Mar 2015102477110
Apr 20152464241
May 20151192121
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Jul 20151041915
Aug 201562139
Sep 2015854328
Oct 2015223347
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Feb 201682919
Mar 2016254531
Apr 201682612
May 2016182623
Jun 2016183626
Jul 2016126230
Aug 2016223231
Sep 201674872
Oct 2016114150
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Jan 201715225
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Mar 201734419
Apr 20175349
May 2017103516
Jun 201732814
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Apr 20185299
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Jun 20182289
Jul 2018102913
Aug 201852713
Sep 201822218
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Total 201854316155
Jan 201922322
Feb 201962416
Mar 201923511
Apr 201911514
May 201971617
Jun 201911919
Jul 201921311
Aug 201911811
Sep 201931713
Oct 20192207
Nov 201952013
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Total 201939234162
Jan 202011418
Feb 202012514
Mar 20202176
Apr 202011412
May 202012013
Jun 202044116
Jul 202062312
Aug 202061316
Sep 202024412
Oct 202042613
Nov 202061813
Dec 202011013
Total 202035265158
Jan 202151312
Total 202151312
Total271020351609

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Keywords

  • Claudin
  • IQGAP1
  • Paracellular permeability
  • Polarized epithelium
  • Tight junction

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Research Article
IQGAP1 controls tight junction formation through differential regulation of claudin recruitment
Barbara E. Tanos, Andres E. Perez Bay, Susana Salvarezza, Igor Vivanco, Ingo Mellinghoff, Mahasin Osman, David B. Sacks, Enrique Rodriguez-Boulan
Journal of Cell Science 2015 128: 853-862; doi: 10.1242/jcs.118703
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Research Article
IQGAP1 controls tight junction formation through differential regulation of claudin recruitment
Barbara E. Tanos, Andres E. Perez Bay, Susana Salvarezza, Igor Vivanco, Ingo Mellinghoff, Mahasin Osman, David B. Sacks, Enrique Rodriguez-Boulan
Journal of Cell Science 2015 128: 853-862; doi: 10.1242/jcs.118703

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