Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Cell Scientists to Watch
    • First Person
    • Sign up for alerts
  • About us
    • About JCS
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Fast-track manuscripts
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • JCS Prize
    • Manuscript transfer network
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contacts
    • Contact JCS
    • Subscriptions
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Journal of Cell Science
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Journal of Cell Science

  • Log in
Advanced search

RSS   Twitter  Facebook   YouTube  

  • Home
  • Articles
    • Accepted manuscripts
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Special issues
    • Subject collections
    • Cell Scientists to Watch
    • First Person
    • Sign up for alerts
  • About us
    • About JCS
    • Editors and Board
    • Editor biographies
    • Travelling Fellowships
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Fast-track manuscripts
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • JCS Prize
    • Manuscript transfer network
    • Biology Open transfer
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contacts
    • Contact JCS
    • Subscriptions
    • Advertising
    • Feedback
Research Article
Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction
Wenshu Lu, Qiongyu Chen, Songmin Ying, Xiaobing Xia, Zhanru Yu, Yuan Lui, George Tranter, Boquan Jin, Chaojun Song, Leonard W. Seymour, Shisong Jiang
Journal of Cell Science 2016 129: 108-120; doi: 10.1242/jcs.175463
Wenshu Lu
1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Qiongyu Chen
1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Songmin Ying
1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiaobing Xia
1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Zhanru Yu
2MRC Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington OX3 9DS, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yuan Lui
2MRC Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington OX3 9DS, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
George Tranter
3Chiralabs Limited, Begbroke Science Park, Woodstock Road, Begbroke, Oxfordshire OX5 1PF, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Boquan Jin
4Department of Immunology, Fourth Military Medical University, Xi'an City 710032, Shaanxi Province, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chaojun Song
4Department of Immunology, Fourth Military Medical University, Xi'an City 710032, Shaanxi Province, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Leonard W. Seymour
1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: len.seymour@oncology.ox.ac.uk shisong.jiang@oncology.ox.ac.uk
Shisong Jiang
1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: len.seymour@oncology.ox.ac.uk shisong.jiang@oncology.ox.ac.uk
  • Article
  • Figures & tables
  • Supp info
  • Info & metrics
  • PDF + SI
  • PDF
Loading

Article Information

vol. 129 no. 1, 108-120

DOI 
https://doi.org/10.1242/jcs.175463
PubMed 
26729029

Published By 
The Company of Biologists Ltd
Print ISSN 
0021-9533
Online ISSN 
1477-9137
History 
  • Received June 11, 2015
  • Accepted November 10, 2015
  • Published online January 4, 2016.
Copyright & Usage 
© 2016. Published by The Company of Biologists Ltd


Author Information

  1. Wenshu Lu1,*,
  2. Qiongyu Chen1,*,
  3. Songmin Ying1,
  4. Xiaobing Xia1,
  5. Zhanru Yu2,
  6. Yuan Lui2,
  7. George Tranter3,
  8. Boquan Jin4,
  9. Chaojun Song4,
  10. Leonard W. Seymour1,‡ and
  11. Shisong Jiang1,‡
  1. 1Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK
  2. 2MRC Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington OX3 9DS, UK
  3. 3Chiralabs Limited, Begbroke Science Park, Woodstock Road, Begbroke, Oxfordshire OX5 1PF, UK
  4. 4Department of Immunology, Fourth Military Medical University, Xi'an City 710032, Shaanxi Province, China
  1. ↵‡Authors for correspondence (len.seymour{at}oncology.ox.ac.uk; shisong.jiang{at}oncology.ox.ac.uk)
  1. ↵* These authors contributed equally to this work

View Abstract

Article usage

Usage statistics are calculated at the beginning of each month for the previous month.

Usage statistics: December 2015 to December 2020

AbstractFullPdf
Dec 2015100
Total 2015100
Jan 20163594140
Feb 20161181617
Mar 20165483
Apr 20169131
May 201615344
Jun 201610275
Jul 2016194016
Aug 2016232910
Sep 2016114017
Oct 2016115330
Nov 201654423
Dec 201654427
Total 2016951329193
Jan 201765023
Feb 201754728
Mar 201724925
Apr 201744617
May 201764226
Jun 201702012
Jul 201713028
Aug 201712326
Sep 201722326
Oct 201734236
Nov 201714420
Dec 201714011
Total 201732456278
Jan 201804524
Feb 201802410
Mar 201803519
Apr 201805718
May 201805931
Jun 20180455
Jul 20181267
Aug 20180626
Sep 201806612
Oct 201836223
Nov 201808737
Dec 201816426
Total 20185632218
Jan 201924810
Feb 201913413
Mar 201923618
Apr 201917314
May 201911918
Jun 20192228
Jul 201912813
Aug 201912223
Sep 2019061436
Oct 201963218
Nov 201922313
Dec 201903317
Total 201919431601
Jan 202032222
Feb 202032514
Mar 202021516
Apr 202002326
May 2020212724
Jun 202032320
Jul 202021413
Aug 202001515
Sep 202042016
Oct 202022225
Nov 202032423
Dec 202082120
Total 202032351234
Total104021991524

Statistics from Altmetric.com

Previous ArticleNext Article
Back to top
Previous ArticleNext Article

This Issue

Keywords

  • TNF
  • NF-κB
  • Apoptosis
  • Necrosis
  • Evolution
  • Overlapping peptides

 Download PDF

Email

Thank you for your interest in spreading the word on Journal of Cell Science.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction
(Your Name) has sent you a message from Journal of Cell Science
(Your Name) thought you would like to see the Journal of Cell Science web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Research Article
Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction
Wenshu Lu, Qiongyu Chen, Songmin Ying, Xiaobing Xia, Zhanru Yu, Yuan Lui, George Tranter, Boquan Jin, Chaojun Song, Leonard W. Seymour, Shisong Jiang
Journal of Cell Science 2016 129: 108-120; doi: 10.1242/jcs.175463
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Research Article
Evolutionarily conserved primary TNF sequences relate to its primitive functions in cell death induction
Wenshu Lu, Qiongyu Chen, Songmin Ying, Xiaobing Xia, Zhanru Yu, Yuan Lui, George Tranter, Boquan Jin, Chaojun Song, Leonard W. Seymour, Shisong Jiang
Journal of Cell Science 2016 129: 108-120; doi: 10.1242/jcs.175463

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Alerts

Please log in to add an alert for this article.

Sign in to email alerts with your email address

Article navigation

  • Top
  • Article
    • ABSTRACT
    • INTRODUCTION
    • RESULTS
    • DISCUSSION
    • MATERIALS AND METHODS
    • Acknowledgements
    • Footnotes
    • References
  • Figures & tables
  • Supp info
  • Info & metrics
  • PDF + SI
  • PDF

Related articles

Cited by...

More in this TOC section

  • Histone chaperone APLF level dictates the implantation of mouse embryos
  • Switching between blebbing and lamellipodia depends on the degree of non-muscle myosin II activity
  • Kindlin-2 promotes rear focal adhesion disassembly and directional persistence during cell migration
Show more RESEARCH ARTICLE

Similar articles

Other journals from The Company of Biologists

Development

Journal of Experimental Biology

Disease Models & Mechanisms

Biology Open

Advertisement

2020 at The Company of Biologists

Despite the challenges of 2020, we were able to bring a number of long-term projects and new ventures to fruition. While we look forward to a new year, join us as we reflect on the triumphs of the last 12 months.


Mole – The Corona Files

"This is not going to go away, 'like a miracle.' We have to do magic. And I know we can."

Mole continues to offer his wise words to researchers on how to manage during the COVID-19 pandemic.


Cell scientist to watch – Christine Faulkner

In an interview, Christine Faulkner talks about where her interest in plant science began, how she found the transition between Australia and the UK, and shares her thoughts on virtual conferences.


Read & Publish participation extends worldwide

“The clear advantages are rapid and efficient exposure and easy access to my article around the world. I believe it is great to have this publishing option in fast-growing fields in biomedical research.”

Dr Jaceques Behmoaras (Imperial College London) shares his experience of publishing Open Access as part of our growing Read & Publish initiative. We now have over 60 institutions in 12 countries taking part – find out more and view our full list of participating institutions.


JCS and COVID-19

For more information on measures Journal of Cell Science is taking to support the community during the COVID-19 pandemic, please see here.

If you have any questions or concerns, please do not hestiate to contact the Editorial Office.

Articles

  • Accepted manuscripts
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Special issues
  • Subject collections
  • Interviews
  • Sign up for alerts

About us

  • About Journal of Cell Science
  • Editors and Board
  • Editor biographies
  • Travelling Fellowships
  • Grants and funding
  • Journal Meetings
  • Workshops
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Fast-track manuscripts
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • JCS Prize
  • Manuscript transfer network
  • Biology Open transfer

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contacts

  • Contact JCS
  • Subscriptions
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2021   The Company of Biologists Ltd   Registered Charity 277992