Summary
Different motile blood cells behave differently on a glass surface. Macrophages go through all the stages of spreading described previously for fibroblasts; granulocytes become polarized after a short stage of radial spreading, while the polarization of lymphocytes takes place immediately upon attachment. The active centrioles of the cells we have studied orient their distal ends towards the upper cell surface. The centrioles in blood cells have a different location with respect to the nucleus and the leading edge of the cell: in macrophages the centrioles are situated mostly anterior to or at the side of the nucleus; in granulocytes they lie between the nuclear segments; and in lymphocytes they are positioned strictly posterior to the nucleus, in the uropod. In each case, however, the centrioles are localized in the central region of the cytoplasm. Their alignment does not appear to be related to the blood cells' random motion in vitro.
- © 1988 by Company of Biologists
Article navigation
Related articles
Cited by...
More in this TOC section
Similar articles
Other journals from The Company of Biologists
2020 at The Company of Biologists
Despite the challenges of 2020, we were able to bring a number of long-term projects and new ventures to fruition. While we look forward to a new year, join us as we reflect on the triumphs of the last 12 months.
Mole – The Corona Files
"This is not going to go away, 'like a miracle.' We have to do magic. And I know we can."
Mole continues to offer his wise words to researchers on how to manage during the COVID-19 pandemic.
Cell scientist to watch – Christine Faulkner
In an interview, Christine Faulkner talks about where her interest in plant science began, how she found the transition between Australia and the UK, and shares her thoughts on virtual conferences.
Read & Publish participation extends worldwide
“The clear advantages are rapid and efficient exposure and easy access to my article around the world. I believe it is great to have this publishing option in fast-growing fields in biomedical research.”
Dr Jaceques Behmoaras (Imperial College London) shares his experience of publishing Open Access as part of our growing Read & Publish initiative. We now have over 60 institutions in 12 countries taking part – find out more and view our full list of participating institutions.
JCS and COVID-19
For more information on measures Journal of Cell Science is taking to support the community during the COVID-19 pandemic, please see here.
If you have any questions or concerns, please do not hestiate to contact the Editorial Office.