PT  - JOURNAL ARTICLE
ED  - , 
TI  - Cell scientist to watch – Hayley Sharpe
AID  - 10.1242/jcs.255869
DP  - 2020 Nov 15
TA  - Journal of Cell Science
PG  - jcs255869
VI  - 133
IP  - 22
4099  - http://jcs.biologists.org/content/133/22/jcs255869.short
4100  - http://jcs.biologists.org/content/133/22/jcs255869.full
SO  - J. Cell Sci.2020 Nov 15; 133
AB  - Hayley Sharpe graduated from the University of Bath, UK, with a degree in biochemistry. She then joined the laboratory of Sean Munro for her PhD in cell and molecular biology at the Medical Research Council Laboratory of Molecular Biology (MRC-LMB) in Cambridge, UK. There, she investigated the properties of protein transmembrane domains embedded within the organelle membranes of the secretory pathway. She next moved to San Francisco, USA, for postdoctoral work at Genentech, where she studied clinical resistance mechanisms to a Hedgehog pathway inhibitor in skin cancer. In 2016, Hayley returned to the UK to establish her own research group at the Cambridge Institute for Medical Research, and in 2019, she moved to the Babraham Institute, also in Cambridge. Her laboratory works on understanding how protein tyrosine phosphatases function in signalling and cell–cell communication, with a particular focus on a family of cell surface receptors. Hayley became part of the EMBO Young Investigator Programme in 2019 and was awarded the Lister Institute Research Prize in 2020.