Table 1.

Reported microfibril and elastic fibre associated molecules

MoleculeChromosomeLocationReferences
Fibrillin-115q21.1Microfibrils Pereira et al., 1993; Baldock et al., 2001
Fibrillin-25q23-q31Microfibrils Zhang et al., 1994
Fibrillin-319p? Microfibrils Nagase et al., 2001
MAGP-11pter — 1qterMicrofibrils Brown-Augsberger et al., 1996
MAGP-212p13.1-p12.3Some microfibrils Gibson et al., 1998
LTBP-12p12-q22Some microfibrils Miyazono et al., 1988; Sinha et al., 1998
LTBP-214q22-q33Microfibrils/elastic fibres Gibson et al., 1995; Bashir et al., 1996
LTBP-311q12? Yin et al., 1995
LTBP-419q13.1? Giltay et al., 1997
Decorin12q13.2Microfibrils Trask et al., 2000a
BiglycanXq28Elastic fibre core Reinboth et al., 2001
Versican5q12-q14Some microfibrils Isogai et al., 2002
MFAP-115q15-q21Some microfibrils Liu et al., 1997
MFAP-35q32-q32.2Some microfibrils Abrams et al., 1995
MFAP-4 (MAGP-36)17p11.2Some microfibrils Lausen et al., 1999; Hirano et al., 2002
Tropoelastin7q11.2Elastic fibre core Mecham and Davis, 1994
Lysyl oxidase (LOX)5q23.3-q31.2Microfibrils/tropoelastin Csiszar, 2001
LOXL8p21.3-p21.2? Borel et al., 2001
LOXL215q22? Csiszar, 2001
LOXL32p13? Csiszar, 2001
BigH3 (keratoepithelin)5q31Elastic fibre/collagen interface Gibson et al., 1997
Fibulin-122q13.3Elastic fibre core Kostka et al., 2001
Fibulin-23p24-25Elastin-microfibril interface Tsuda et al., 2001
Fibulin-514q32.1Elastic fibre—cell interface Nakamura et al., 2002; Yanagisawa et al., 2002
Emilin-12p23Elastin-microfibril interface Doliana et al., 1999
Emilin-218p11.3Elastin-microfibril interface Doliana et al., 2001
Elastin-binding protein3p21.33Newly secreted tropoelastin Prody et al., 1998
Vitronectin17q11Some microfibrils Dählback et al., 1990
AmyloidSome microfibrils Dählback et al., 1990
Collagen VIII [α1(VIII)]3q12-q13.1Some elastic fibres Sadawa and Konomi, 1991
Collagen XVI [α1(XVI)]1p34Dermal microfibrils Grässel et al., 1999
Endostatin [α1(XVIII)]21q22.3Vascular elastic fibres Miosge et al., 1999
Collagen VISome microfibrils Finnis and Gibson, 1997
[α1(VI) α2(VI)]21q22.3
[α3(VI)]2q37