Table 1.

Effect of phospholipase A2 neurotoxin intoxication on the twitch of mouse phrenic-nerve hemidiaphragm preparations

Concentration Maximum facilitation (% ctr)* Duration of facilitation (minutes) Paralysis time (minutes)
β-BTx 3 μg ml-1 140.7±7 17±2.6 148±6.1
Taipoxin 1 μg ml-1 138.8±9 19.5±1.3 56.4±6.7
Notexin 1 μg ml-1 ND ND 42±2.8
Textilotoxin 1 μg ml-1 127±6.2 24.3±5.1 76.7±5.7
  • Data are means of three different experiments; ND, not determined.

  • * Percentage with respect to the control twitch (i.e. before adding tonin)