Table 2.

Localization of calpains

Localization Isoform References
Adhesion comple xes Capn2 Beckerle et al., 1987
Caveolae Capn2 Kifor et al., 2003
Diffuse cytoplasmic Capn1, 2, 5, 7, 10, CSS1 Gafni et al., 2004; Gil-Parrado et al., 2003; Lane et al., 1992; Raynaud et al., 2004
Endoplasmic reticulum Capn1, 2, CSS1 Hood et al., 2004; Hood et al., 2003; Sakai et al., 1989
Extracellular Capn1, 2 Nishihara et al., 2001; Raynaud et al., 2004; Xu and Deng, 2004
Golgi Capn1, 2, CSS1 Hood et al., 2004; Hood et al., 2003
Lipid rafts Capn2 Morford et al., 2002; P. Nuzzi and A.H., unpublished data
Nuclear Capn1, 2, 5, 7, 10, CSS1 Gafni et al., 2004; Gil-Parrado et al., 2003; Mellgren and Lu, 1994; Raynaud et al., 2004; Tremper-Wells and Vallano, 2005
Plasma membrane Capn1, CSS1 Gil-Parrado et al., 2003; Lane et al., 1992; Sakai et al., 1989